Great Dane Adoption in Mebane, NC: Great Dane Puppies for Sale in Mebane, NC

Adopt a Great Dane near you in Mebane, North Carolina

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Mebane, North Carolina

These Great Danes are available for adoption close to Mebane, North Carolina.

Mouse

Great Dane Mixed Breed (Medium)

Female, 4 yrs 1 mo

Durham, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

Mouse is a gentle 4-year-old Great Dane. True to her breed, she’s not a high-energy dog—she’s happiest with a nice walk, some thoughtful training time and play, and plenty of cozy moments on the couch. Once she trusts you, she loves to cuddle and will happily wag her little tail with just words of affirmation. Mouse finds confidence through structure and positive reinforcement. She likes playing with other dogs, though—as with many Great Danes—she needs thoughtful boundaries to avoid over-exercising and to support her long-term health. Her ideal home will understand the importance of moderation and ongoing care that helps giant breeds thrive. When Mouse first came into our care, she was very fearful of the world around her. Through patience and consistent support, she’s blossomed into a loving, affectionate companion. She’s still a cautious girl—very gentle, but sensitive—and will need continued, proper socialization to help her flourish. Mouse would do best with adopters who are committed to her long-term physical and emotional well-being. In return, she offers quiet devotion, a loving presence, and the kind of bond that feels incredibly special because you earned it. Mouse is house trained, can walk on leash, knows some basic commands, and is doing well building recall so far. Due to her size, we recommend a home without small children. If you’re looking for a sweet, tender giant who just wants to feel safe and loved, Mouse might be your girl. 💛

Learn More

Tito

Great Dane

Male, 4 yrs 7 mos

Stokesdale, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Not good with kids, Not good with dogs, Not good with cats,

Story

Are you ready to be captured by the charm of a huge dog? Look no further, this is Tito. Tito is a 3-year-old Great Dane looking for his forever home when his previous home did not work out for him. This boy is already housebroken, crate trained and gets along great with other dogs. We are looking for a home for this small horse (approximately 110 lbs.) that has previous giant breed experience and does not have young children in the home. Tito loves car rides, attention and enjoying the finer things in life like a comfortable afternoon nap. If your home is looking for a handsome addition look no further and visit us at reddogfarm.com to fill out an application.

Learn More

Kane (Courtesy)

Great Dane

Male, Adult

Holly Springs, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Not good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

You can fill out an adoption application online on our official website. Online Adoption Application › KaneGreensboro, NC 16 monthsGreat Dane 90 poundsneuteredUp to date on shots? Yes Did you get the dog as a puppy or adult? Puppy (4 months) Has the dog had any formal training with a trainer? No Good with kids? Yes but wouldn’t recommend him in a home with one Good with strangers? No Good with chickens/ farm animals? UnsureGood with dogs of all sizes and gender? YesGood with cats? UnsureWhat does the dog enjoy? Loves running, playing ball, defluffing toys, attention What does the dog dislike? Strangers, sudden movements, car rides, feet being touchedCrate trained, house trained, leash trained? Yes, allDoes the dog know specific commands? Yes: Sit, down, stay, wait, knows not to go out of a door unless I say “let’s go”. Does the dog have any issues with health? NoAre vet records available? YesIs there agression? YesWhat are the triggers? Getting too hyper, Him doing something wrong and fearing discipline, Unknown situations, strangers (especially men) Food aggression? NoGuard toys? Sometimes (over other dogs)Has the dog been socialized in public? YesFood Allergies? ChickenEnvironmental Allergies? NoDoes the dog enjoy car rides? NoIs there any anxiety? SometimesWhat causes the anxiety? When he’s left aloneWhere does the dog normally sleep? CrateHow long does the dog go between potty breaks? Whenever he needs to go out or 8 hours during a work day (crated). Walk the dog to pottyDo you have steps and can the dog maneuver them? YesAny other issues the dog has that we need to monitor? NoWhy is the dog being rehomed? I can’t meet his needs. I am unsure of how to care properly for an aggressive dog. What do you feel would be a perfect home for the dog? Large fenced in backyard or someone who doesn’t mind taking him somewhere he can get out energy and run. This boy loves to run. No small kids but I think older kids would be fine (as long as the family knows the risks). Had the resources to get him the training he deserves, someone that is patient and kind and loving to him and willing to put in the work to understand his triggers. Could do well as an only dog but has always had doggie siblings.Visit this organization's web site to see any additional information available about this pet.January 6, 2026, 11:42 am

Learn More

Steve Harrington

Great Dane

Male, 3 mos

Raleigh, NC

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs, House-trained,

Story

✨ Meet Steve Harrington ✨ Yes, that Steve Harrington, because much like the Stranger Things icon, this guy is impossibly handsome, wildly lovable, and rocking the most perfect floppy ears you’ve ever seen. Steve was found wandering downtown alone about two weeks ago, all skin and bones, trying to figure life out way too young. A friend scooped him up, and he’s been crashing with us ever since. While most rescues are full and the local shelter is closed for repairs (it’s rough out there for a homeless pup), we’re covering his care ourselves until we can find him what he really needs: a forever home. Steve is around 12 weeks old and already 25 pounds, so let’s be clear ... this is not a purse dog. The vet and I both suspect he’s a Great Dane mix, which means he’s on track to be a 100+ lb gentle giant. Big dog people, this is your moment. Despite his size, Steve is pure sunshine. He’s incredibly smart, crate trained, sleeping through the night, and hasn’t had an accident indoors in over a week (honestly, he’s showing off). He loves going for walks, sunbathing in the yard, chewing on sticks like it’s his job, and occasionally unleashing some truly impressive puppy zoomies. He plays beautifully with our two large dogs and can absolutely hold his own. Most importantly: Steve loves people. Like, deeply. Everyone he meets is immediately his best friend, and he’s generous with kisses. Consider yourself warned!

Learn More

Xerxes

Great Dane

Male, Puppy

Raleigh, NC

Size

(when grown) -

Details

Story

Primary Color: Black Weight: 18.5 Age: 0yrs 3mths 0wks

Learn More

Enid

Great Dane

Female, 7 mos

Garner, NC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, Shots are up-to-date,

Story

Welcome Wednesday and Enid to the ranch!!!Available for foster or forever now! GORGEOUS 6 month lab mix puppies Up-to-date and microchipped Good with dogs, cats and kids In Foster with master certified dog trainer Ready to go home now!!!!Statesville, NC Let's share them everywhere and get them home!!! ##2565560##

Learn More

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Mebane, North Carolina.

Great Dane puppies and dogs in Mebane, North Carolina

Learn More:

Adopt a Great Dane near you in Mebane, North Carolina

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Mebane, North Carolina

These Great Danes are available for adoption close to Mebane, North Carolina.

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in nearby cities

Related breeds in Mebane, North Carolina

Great Dane shelters & rescues in Mebane, North Carolina

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog?

Great Dane basics

Great Dane basics

Home

Adopt a Dog

Adopt a Great Dane

North Carolina

Mebane

Great Dane puppies and dogs in Mebane, North Carolina

Learn More:

Adopt a Great Dane near you in Mebane, North Carolina

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Mebane, North Carolina

These Great Danes are available for adoption close to Mebane, North Carolina.

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in nearby cities

Related breeds in Mebane, North Carolina

Great Dane shelters & rescues in Mebane, North Carolina

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog?

Great Dane basics

Great Dane basics