Adopt

Great Dane puppies and dogs in Sanford, North Carolina

Looking for a Great Dane puppy or dog in Sanford, North Carolina? Adopt a Pet can help you find an adorable Great Dane near you.

Picture of Great Dane

Adopt a Great Dane near you in Sanford, North Carolina

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Sanford, North Carolina

These Great Danes are available for adoption close to Sanford, North Carolina.
Photo of Kane (Courtesy)

Kane (Courtesy)

Great Dane

Male, Adult
Holly Springs, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website. Online Adoption Application › KaneGreensboro, NC 16 monthsGreat Dane 90 poundsneuteredUp to date on shots? Yes Did you get the dog as a puppy or adult? Puppy (4 months) Has the dog had any formal training with a trainer? No Good with kids? Yes but wouldn’t recommend him in a home with one Good with strangers? No Good with chickens/ farm animals? UnsureGood with dogs of all sizes and gender? YesGood with cats? UnsureWhat does the dog enjoy? Loves running, playing ball, defluffing toys, attention What does the dog dislike? Strangers, sudden movements, car rides, feet being touchedCrate trained, house trained, leash trained? Yes, allDoes the dog know specific commands? Yes: Sit, down, stay, wait, knows not to go out of a door unless I say “let’s go”. Does the dog have any issues with health? NoAre vet records available? YesIs there agression? YesWhat are the triggers? Getting too hyper, Him doing something wrong and fearing discipline, Unknown situations, strangers (especially men) Food aggression? NoGuard toys? Sometimes (over other dogs)Has the dog been socialized in public? YesFood Allergies? ChickenEnvironmental Allergies? NoDoes the dog enjoy car rides? NoIs there any anxiety? SometimesWhat causes the anxiety? When he’s left aloneWhere does the dog normally sleep? CrateHow long does the dog go between potty breaks? Whenever he needs to go out or 8 hours during a work day (crated). Walk the dog to pottyDo you have steps and can the dog maneuver them? YesAny other issues the dog has that we need to monitor? NoWhy is the dog being rehomed? I can’t meet his needs. I am unsure of how to care properly for an aggressive dog. What do you feel would be a perfect home for the dog? Large fenced in backyard or someone who doesn’t mind taking him somewhere he can get out energy and run. This boy loves to run. No small kids but I think older kids would be fine (as long as the family knows the risks). Had the resources to get him the training he deserves, someone that is patient and kind and loving to him and willing to put in the work to understand his triggers. Could do well as an only dog but has always had doggie siblings.Visit this organization's web site to see any additional information available about this pet.March 7, 2026, 6:01 pm
Photo of Banjo

Banjo

Great Dane Mixed Breed (Large)

Male, 2 yrs 3 mos
FUQUAY VARINA, NC
Size
(when grown) -
Details
Spayed or Neutered,
Story
Have you ever wanted to cuddle a pony? Meet BANJO Well, Banjo is as close as it gets. At 123lbs, he has nothing but giant snuggles to give. Banjo is 3/4 Great Dane and 1/4 Great Pyrenees, and 100% wonderful. If you are familiar with a giant breed, he has all of the attributes, including the slobber. Good with cats, dogs, and grown-ups but nervous around tiny humans who don’t yet understand dog boundaries. He lived with children prior to coming to the US Dog Coalition and Rescue and would do great with children out of the toddler stage. He walks like a dream on a leash and is a very good boy in the car. He’s happiest with his people and gets a little anxious in his kennel when left alone, but he is working hard on that and is making great strides with the help of our trainer. He’s working on getting more confident and would do well with someone who understands his giant-baby needs, but will make someone the very best friend. If you would like to meet Banjo please fill out an adoption application here: www.usdogcoalition.org/adoptions
Photo of Nyx & Remy

Nyx & Remy

Great Dane

Female, Young
Raeford, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
This post is for two dogs. Would prefer to keep them together. They are sisters, age 15 months. Need to rehome due to me and my husband having to go back on the road as truck drivers. They are house trained and crate trained but still have some accidents. They have not been spayed as we were waiting on their first heat cycle. One is currently in heat, the other still has not had a cycle.
Photo of Nova

Nova

Great Dane Labrador Retriever

Female, Adult
Fayetteville, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Loves cats and other dogs, very loving and cuddly, protective of house and home members. The reason she needs rehome is that she has a ton of energy and me and my pregnant wife can’t get her the exercise she needs, because of this she frequently tears things up and has been knocking my wife to the ground for the past few weeks out of excitement and just pure goofiness, which was cute before my wife got pregnant now it’s a huge safety concern for my wife and my child as nova has shown no sign of calming down and I can’t be home constantly to calm her or be her outlet. She is a sweet dog and hasn’t done anything wrong or bad she just doesn’t understand she can’t knock my wife into things and the ground and tear everything up just cause we can’t take her for 2-3 walks everyday anymore. She wasn’t this energy filled when we first got her but now she’s running rampant through the house with playful energy and it is just not a good fit for a pregnant small woman and other small animals.
Photo of Hamlet

Hamlet

Great Dane

Male, Young
Raleigh, NC
Size
(when grown) -
Details
-
Story
Primary Color: Yellow Gold Weight: 83 Age: 0yrs 8mths 1wks
Photo of Misty (bonded w/ Penny)

Misty (bonded w/ Penny)

Great Dane Mastiff

Female, 3 yrs 3 mos
Wendell, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Misty! Misty and her sister Penny are looking for their forever home together. These girls are littermates and have spent their whole lives together. House broken, dog friendly, and fully vetted, they're hoping to find a home that loves them both! These gentle giants (and big lap puppies!) Would fit in most homes, but we would advise no small animals or small children due to their size.  ##2649812##

Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Sanford, North Carolina.

Great Dane puppies and dogs in nearby cities

Related breeds in Sanford, North Carolina

Great Dane shelters & rescues in Sanford, North Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Sanford, North Carolina. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

22.2 miles

Pawfect Match Rescue and Rehabilitation

Holly Springs, NC 27540

Pet Types: dogs

More an arrow icon

Rescue

24 miles

US Dog Coalition and Rescue

FUQUAY VARINA, NC 27526

Pet Types: dogs

More an arrow icon

Shelter

39.4 miles

Wake County Animal Center

820 Beacon Lake Drive, Raleigh, NC 27610

Pet Types: cats, birds, dogs, rabbits, small animals

More an arrow icon

Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

magnifying glass with cat and dog

Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

clipboard with list

Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

Learn More an arrow icon