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Great Dane puppies and dogs in Fuquay Varina, North Carolina

Looking for a Great Dane puppy or dog in Fuquay Varina, North Carolina? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Fuquay Varina, North Carolina

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Or, how about these Great Danes in cities near Fuquay Varina, North Carolina

These Great Danes are available for adoption close to Fuquay Varina, North Carolina.
We'll also keep you updated on Kane (Courtesy)'s adoption status with email updates.
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Kane (Courtesy)

Great Dane

Male, Adult
Holly Springs, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website. Online Adoption Application › KaneGreensboro, NC 16 monthsGreat Dane 90 poundsneuteredUp to date on shots? Yes Did you get the dog as a puppy or adult? Puppy (4 months) Has the dog had any formal training with a trainer? No Good with kids? Yes but wouldn’t recommend him in a home with one Good with strangers? No Good with chickens/ farm animals? UnsureGood with dogs of all sizes and gender? YesGood with cats? UnsureWhat does the dog enjoy? Loves running, playing ball, defluffing toys, attention What does the dog dislike? Strangers, sudden movements, car rides, feet being touchedCrate trained, house trained, leash trained? Yes, allDoes the dog know specific commands? Yes: Sit, down, stay, wait, knows not to go out of a door unless I say “let’s go”. Does the dog have any issues with health? NoAre vet records available? YesIs there agression? YesWhat are the triggers? Getting too hyper, Him doing something wrong and fearing discipline, Unknown situations, strangers (especially men) Food aggression? NoGuard toys? Sometimes (over other dogs)Has the dog been socialized in public? YesFood Allergies? ChickenEnvironmental Allergies? NoDoes the dog enjoy car rides? NoIs there any anxiety? SometimesWhat causes the anxiety? When he’s left aloneWhere does the dog normally sleep? CrateHow long does the dog go between potty breaks? Whenever he needs to go out or 8 hours during a work day (crated). Walk the dog to pottyDo you have steps and can the dog maneuver them? YesAny other issues the dog has that we need to monitor? NoWhy is the dog being rehomed? I can’t meet his needs. I am unsure of how to care properly for an aggressive dog. What do you feel would be a perfect home for the dog? Large fenced in backyard or someone who doesn’t mind taking him somewhere he can get out energy and run. This boy loves to run. No small kids but I think older kids would be fine (as long as the family knows the risks). Had the resources to get him the training he deserves, someone that is patient and kind and loving to him and willing to put in the work to understand his triggers. Could do well as an only dog but has always had doggie siblings.Visit this organization's web site to see any additional information available about this pet.January 6, 2026, 11:42 am

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We'll also keep you updated on Enid's adoption status with email updates.
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Enid

Great Dane Greater Swiss Mountain Dog

Female, 7 mos
Garner, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Shots are up-to-date,
Story
Welcome Wednesday and Enid to the ranch!!!Available for foster or forever now!  GORGEOUS 6 month lab mix puppies Up-to-date and microchipped Good with dogs, cats and kids In Foster with master certified dog trainer Ready to go home now!!!!Statesville, NC  Let's share them everywhere and get them home!!! ##2565560##

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We'll also keep you updated on Wednesday's adoption status with email updates.
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Wednesday

Great Dane

Female, 7 mos
Garner, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Shots are up-to-date,
Story
Welcome Wednesday and Enid to the ranch!!!Available for foster or forever now!  GORGEOUS 6 month lab mix puppies Up-to-date and microchipped Good with dogs, cats and kids In Foster with master certified dog trainer Ready to go home now!!!!Statesville, NC  Let's share them everywhere and get them home!!! ##2565558##

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We'll also keep you updated on Misty (bonded w/ Penny)'s adoption status with email updates.
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Misty (bonded w/ Penny)

Great Dane Mastiff

Female, 3 yrs
Wendell, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Misty! Misty and her sister Penny are looking for their forever home together. These girls are littermates and have spent their whole lives together. House broken, dog friendly, and fully vetted, they're hoping to find a home that loves them both! These gentle giants (and big lap puppies!) Would fit in most homes, but we would advise no small animals or small children due to their size.  ##2649812##

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We'll also keep you updated on Penny (bonded w/ Misty!)'s adoption status with email updates.
Photo of Penny (bonded w/ Misty!)

Penny (bonded w/ Misty!)

Great Dane Mastiff

Female, 3 yrs
Wendell, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Penny! Penny and her sister Misty are 3 year old great dane × mastiffs who are looking for their forever home. Their owners surrendered them due to no fault of their own.  Together their entire lives, these girls need to stay together. They are good with other dogs, house broken, and fully vetted. These gentle giants are sweet and need someone to love them! We wouldn't recommend them for small animals, or small children just due to their size.  ##2649811##

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We'll also keep you updated on Mouse's adoption status with email updates.
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Mouse

Great Dane Mixed Breed (Medium)

Female, 4 yrs 1 mo
Durham, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
Mouse is a gentle 4-year-old Great Dane. True to her breed, she’s not a high-energy dog—she’s happiest with a nice walk, some thoughtful training time and play, and plenty of cozy moments on the couch. Once she trusts you, she loves to cuddle and will happily wag her little tail with just words of affirmation. Mouse finds confidence through structure and positive reinforcement. She likes playing with other dogs, though—as with many Great Danes—she needs thoughtful boundaries to avoid over-exercising and to support her long-term health. Her ideal home will understand the importance of moderation and ongoing care that helps giant breeds thrive. When Mouse first came into our care, she was very fearful of the world around her. Through patience and consistent support, she’s blossomed into a loving, affectionate companion. She’s still a cautious girl—very gentle, but sensitive—and will need continued, proper socialization to help her flourish. Mouse would do best with adopters who are committed to her long-term physical and emotional well-being. In return, she offers quiet devotion, a loving presence, and the kind of bond that feels incredibly special because you earned it. Mouse is house trained, can walk on leash, knows some basic commands, and is doing well building recall so far. Due to her size, we recommend a home without small children. If you’re looking for a sweet, tender giant who just wants to feel safe and loved, Mouse might be your girl. 💛

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Great Dane shelters & rescues in Fuquay Varina, North Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Fuquay Varina, North Carolina. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

3.3 miles

Pawfect Match Rescue and Rehabilitation

Holly Springs, NC 27540

Pet Types: dogs

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Rescue

11.7 miles

Rustys Rescue Ranch

267 Timber Dr. #1895, Garner, NC 27529

Pet Types: cats, dogs

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Rescue

26.2 miles

Carolina Animal Network

Wendell, NC 27591

Pet Types: cats, dogs

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Rescue

30.5 miles

Hope Animal Rescue

Durham, NC 27704

Pet Types: dogs

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If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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