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Great Dane puppies and dogs in Holly Springs, North Carolina

Looking for a Great Dane puppy or dog in Holly Springs, North Carolina? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Holly Springs, North Carolina

These Great Danes are available in Holly Springs, North Carolina.
Photo of Kane (Courtesy)

Kane (Courtesy)

Great Dane

Male, Adult
Holly Springs, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website. Online Adoption Application › KaneGreensboro, NC 16 monthsGreat Dane 90 poundsneuteredUp to date on shots? Yes Did you get the dog as a puppy or adult? Puppy (4 months) Has the dog had any formal training with a trainer? No Good with kids? Yes but wouldn’t recommend him in a home with one Good with strangers? No Good with chickens/ farm animals? UnsureGood with dogs of all sizes and gender? YesGood with cats? UnsureWhat does the dog enjoy? Loves running, playing ball, defluffing toys, attention What does the dog dislike? Strangers, sudden movements, car rides, feet being touchedCrate trained, house trained, leash trained? Yes, allDoes the dog know specific commands? Yes: Sit, down, stay, wait, knows not to go out of a door unless I say “let’s go”. Does the dog have any issues with health? NoAre vet records available? YesIs there agression? YesWhat are the triggers? Getting too hyper, Him doing something wrong and fearing discipline, Unknown situations, strangers (especially men) Food aggression? NoGuard toys? Sometimes (over other dogs)Has the dog been socialized in public? YesFood Allergies? ChickenEnvironmental Allergies? NoDoes the dog enjoy car rides? NoIs there any anxiety? SometimesWhat causes the anxiety? When he’s left aloneWhere does the dog normally sleep? CrateHow long does the dog go between potty breaks? Whenever he needs to go out or 8 hours during a work day (crated). Walk the dog to pottyDo you have steps and can the dog maneuver them? YesAny other issues the dog has that we need to monitor? NoWhy is the dog being rehomed? I can’t meet his needs. I am unsure of how to care properly for an aggressive dog. What do you feel would be a perfect home for the dog? Large fenced in backyard or someone who doesn’t mind taking him somewhere he can get out energy and run. This boy loves to run. No small kids but I think older kids would be fine (as long as the family knows the risks). Had the resources to get him the training he deserves, someone that is patient and kind and loving to him and willing to put in the work to understand his triggers. Could do well as an only dog but has always had doggie siblings.Visit this organization's web site to see any additional information available about this pet.March 7, 2026, 6:01 pm

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Photo of Nala

Nala

Pit Bull Terrier Great Dane

Female, Young
Holly Springs, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website. Online Adoption Application › Nala | 6 months | 47lbs | approx 90lbs fully grown | Good with Dogs | Good with Kids  Hi I'm Nala, I was originally adopted when I was 2 months old, but sadly, my family couldn't keep me because they didn't have enough time to help me get all my wiggles out. Pawfect match rescued me so now i'm ready for my forever home! Like any puppy, I have a lot of energy that comes in spurts, and then I'm content to nap a couple of hours, preferably as close to you as possible. I would love to be your new lap dog-- I have no idea how big I am or how much bigger I'm going to be when I grow up, thanks to my Great Dane genes.  Take a look at my paws.  They are bigger than my new buddy Bella's paws who is 80 lbs (Shepherd in pics). Goofball is my middle name. I love to play with my foster family's dogs, and I'm doing my best to convince the little dog that I'm a friendly giant, play bowing as low as I possibly can, and kissing her chin, but until she agrees to play with me, I'm content to run around and play with the bigger dogs. My ideal home will be with someone who can be with me most of the time, and is willing to continue to train me well so I grow up with good manners. Most of all, I'm a huge lovebug and I just want to love you. For more photos: https://www.pawfectmatch.org/animals/detail?AnimalID=22483021 The adoption fee is $400, which covers vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet. All dogs receive a wellness visit and are up to date on shots appropriate for age. Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an application! Visit this organization's web site to see any additional information available about this pet.June 17, 2026, 9:15 am

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Or, how about these Great Danes in cities near Holly Springs, North Carolina

These Great Danes are available for adoption close to Holly Springs, North Carolina.
Photo of Kane (Courtesy)

Kane (Courtesy)

Great Dane

Male, Adult
Holly Springs, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website. Online Adoption Application › KaneGreensboro, NC 16 monthsGreat Dane 90 poundsneuteredUp to date on shots? Yes Did you get the dog as a puppy or adult? Puppy (4 months) Has the dog had any formal training with a trainer? No Good with kids? Yes but wouldn’t recommend him in a home with one Good with strangers? No Good with chickens/ farm animals? UnsureGood with dogs of all sizes and gender? YesGood with cats? UnsureWhat does the dog enjoy? Loves running, playing ball, defluffing toys, attention What does the dog dislike? Strangers, sudden movements, car rides, feet being touchedCrate trained, house trained, leash trained? Yes, allDoes the dog know specific commands? Yes: Sit, down, stay, wait, knows not to go out of a door unless I say “let’s go”. Does the dog have any issues with health? NoAre vet records available? YesIs there agression? YesWhat are the triggers? Getting too hyper, Him doing something wrong and fearing discipline, Unknown situations, strangers (especially men) Food aggression? NoGuard toys? Sometimes (over other dogs)Has the dog been socialized in public? YesFood Allergies? ChickenEnvironmental Allergies? NoDoes the dog enjoy car rides? NoIs there any anxiety? SometimesWhat causes the anxiety? When he’s left aloneWhere does the dog normally sleep? CrateHow long does the dog go between potty breaks? Whenever he needs to go out or 8 hours during a work day (crated). Walk the dog to pottyDo you have steps and can the dog maneuver them? YesAny other issues the dog has that we need to monitor? NoWhy is the dog being rehomed? I can’t meet his needs. I am unsure of how to care properly for an aggressive dog. What do you feel would be a perfect home for the dog? Large fenced in backyard or someone who doesn’t mind taking him somewhere he can get out energy and run. This boy loves to run. No small kids but I think older kids would be fine (as long as the family knows the risks). Had the resources to get him the training he deserves, someone that is patient and kind and loving to him and willing to put in the work to understand his triggers. Could do well as an only dog but has always had doggie siblings.Visit this organization's web site to see any additional information available about this pet.March 7, 2026, 6:01 pm

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Banjo

Great Dane Mixed Breed (Large)

Male, 2 yrs 4 mos
FUQUAY VARINA, NC
Size
(when grown) -
Details
Spayed or Neutered,
Story
Have you ever wanted to cuddle a pony? Meet BANJO Well, Banjo is as close as it gets. At 123lbs, he has nothing but giant snuggles to give. Banjo is 3/4 Great Dane and 1/4 Great Pyrenees, and 100% wonderful. If you are familiar with a giant breed, he has all of the attributes, including the slobber. Good with cats, dogs, and grown-ups but nervous around tiny humans who don’t yet understand dog boundaries. He lived with children prior to coming to the US Dog Coalition and Rescue and would do great with children out of the toddler stage. He walks like a dream on a leash and is a very good boy in the car. He’s happiest with his people and gets a little anxious in his kennel when left alone, but he is working hard on that and is making great strides with the help of our trainer. He’s working on getting more confident and would do well with someone who understands his giant-baby needs, but will make someone the very best friend. If you would like to meet Banjo please fill out an adoption application here: www.usdogcoalition.org/adoptions

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Photo of Hamlet

Hamlet

Great Dane

Male, Young
Raleigh, NC
Size
(when grown) -
Details
Spayed or Neutered,
Story
Hamlet may only be 8 months old, but he's already mastered many of the skills that make for an ideal work-from-home companion. He's often found quietly resting in his kennel, patiently waiting for visitors to stop by. Hamlet knows sit, takes treats gently, doesn't beg, appears potty trained, and walks beautifully on leash. While you finish conference calls and answer emails, he'll happily relax nearby. Like many adolescent dogs, Hamlet is still polishing his social skills with other dogs. With appropriate guidance and confident canine friends, his playful, fun-loving personality quickly shines through, making him an engaging companion both at home and out exploring.He is up to date on vaccinations, flea/tick and heartworm prevention, is microchipped, and will be neutered prior to going home. If you have dogs or cats, we recommend slow introductions over time. If you have children in your home, we recommend supervision between animals and children at all times.If you're interested in learning more about him, please reach out to our volunteer matchmakers at wcac.matchmaker@gmail.com with the subject line "Hamlet, 268734". Primary Color: Yellow Gold Weight: 85 Age: 0yrs 9mths 0wks

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Photo of Coffee

Coffee

Great Dane

Male, 3 mos
Raleigh, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs,
Story
With his gorgeous silver face, striking hazel eyes, and sweet personality, Coffee is ready to brew up some love in his forever home! Coffee is a gorgeous Dane mix puppy who is as affectionate as they come. He loves to snuggle, enjoys being close to his people, and has the sweetest, most gentle nature. He's also a smart little guy who is eager to learn. Because he's highly food motivated, training is progressing quickly, and he's already showing just how clever he is. Coffee loves other dogs and would be happy in a home with canine companions or as the center of attention. He has a healthy curiosity about the world around him and a moderate energy level—playful enough for adventures, but happy to curl up for cuddles when the day is done. Like any young puppy, Coffee's future family should be prepared to continue basic puppy training and help him build on the great foundation he's already started. The good news is that he's catching on quickly! He is doing very well with potty training so far and is eager to learn when treats and praise are involved. While his mom is a large Dane mix, dad is unknown. Based on Coffee's current size and weight, we expect him to grow into a medium-to-large-sized dog rather than a giant breed. Coffee is a healthy, happy baby boy with a heart full of love and so much potential. If you're looking for a loyal companion, a snuggle buddy, and a best friend all wrapped up in one adorable puppy package, Coffee may be your perfect match.

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Photo of Bowie

Bowie

Great Dane

Female, 3 mos
Raleigh, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Gorgeous, cool, and cuddly - say hello to Bowie. Like a true Pisces, she can go with the flow and is up for any adventure but is also happy with a snuggly night in. Named after the infamous David Bowie, she too has a natural flare. I mean, how many pups do you know that have a paw with rotating black & white toenails? This great dane beauty has been working on all her puppy skills - she's doing great with her crate training, leash work, and sitting for treats. She's no rebel rebel but she is a puppy and will continue to need your support with all of these skills. Bowie has been a rockstar at meeting humans and pups alike. Just think, with her you could be heros every day. Local and out of state applications will be considered.

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Photo of Freddie

Freddie

Great Dane

Male, 3 mos
Raleigh, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Do you like a guy with deep brown eyes who likes long walks just as much as he likes to cuddle? Well, Freddie is your guy. This Pisces pup is here for all your feels. Named after the legend, Freddie Mercury, he too is bigger than life - because, to start, he's a great dane. Freddie brings the style with a fancy freckled foot and he brings the talent - he is doing great with his crate training, leash work, and sits for treats. He has been enjoying meeting all his fans - human and pup - but he's a puppy and will continue to need support. He has all the makings of a best friend.

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These pups are in Holly Springs, North Carolina too!

Below are our newest added Great Danes available for adoption in Holly Springs, North Carolina. To see more adoptable Great Danes in Holly Springs, North Carolina, use the search tool below to enter specific criteria!
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Sadie Mae

American Staffordshire Terrier Bullmastiff

Female, Adult
Holly Springs, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website. Online Adoption Application › We pulled Sadie Mae from Rowan County animal shelter hours from euthanasia! She is completely house trained and walks extremely well on leash, no pulling at all! She does not need a kennel but will use one. She adores all people, but is at her happiest around kiddos! Sadie Mae needs a home without any other dogs, She does not like to share her people! However, Sadie does join us at our adoption events and she does well with the dogs when they are passing by and as long as they mind her space! She does not want or snap, she just doesn’t like other doggies in her face, understandable! Sadie is so so sweet and everybody loves her so much, she would be the perfect dog for a family!  The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet.  All dogs receive a wellness visit and are up to date on shots appropriate for age.  Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an applicationVisit this organization's web site to see any additional information available about this pet.June 17, 2026, 9:15 am

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Photo of ANNIE aka Mocha

ANNIE aka Mocha

American Staffordshire Terrier Bullmastiff

Female, Adult
Holly Springs, NC
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Not good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. Online Adoption Application › Annie, affectionately known as Mocha, is a sweet, smart and loving 16 month old American Staffordshire Terrrier mix.  She is eager to please and thrives on one on one attention, making her the perfect companion for anyone that does not have other pets.    She is house and crate trained, will sit, wait to be given the take command to take a treat,  come when called and understands ‘go lay down’ and ‘crate’.  She lives to go on walks and likes car rides. .    She is smart and a quick learner.  She loves her bones and toys but does think pillows fall into that category as she loves to liberate the fluff in dog toys.  She is very gentle and will let you take food or toys away with no trouble.    She is very affectionate with people and will alert you to people near the house but does not get along with other dogs.  Mocha would be the perfect addition to a family that is looking for a sweet loyal companion that can show her love and attention but have no other pets.The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet.  All dogs receive a wellness visit and are up to date on shots appropriate for age.  Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an applicationVisit this organization's web site to see any additional information available about this pet.June 17, 2026, 9:15 am

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Holly Springs, North Carolina.

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Great Dane shelters & rescues in Holly Springs, North Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Holly Springs, North Carolina. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

0 miles

Pawfect Match Rescue and Rehabilitation

Holly Springs, NC 27540

Pet Types: dogs

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Rescue

3.3 miles

US Dog Coalition and Rescue

FUQUAY VARINA, NC 27526

Pet Types: dogs

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Shelter

17.2 miles

Wake County Animal Center

820 Beacon Lake Drive, Raleigh, NC 27610

Pet Types: cats, birds, dogs, rabbits, small animals

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Rescue

24.2 miles

Freedom Ride Rescue - Raleigh, NC

Raleigh, NC 27604

Pet Types: dogs

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Rescue

27.9 miles

Carolina Animal Network

Wendell, NC 27591

Pet Types: cats, dogs

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Rescue

30.1 miles

Saving Grace Animals for Adoption

PO Box 1649, Wake Forest, NC 27588

Pet Types: dogs, farm animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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