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Mastiff puppies and dogs in Worcester, Massachusetts

Looking for a Mastiff puppy or dog in Worcester, Massachusetts? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Worcester, Massachusetts Other pups in Worcester, Massachusetts Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Worcester, Massachusetts Mastiff shelters and rescues in Worcester, Massachusetts Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Worcester, Massachusetts

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Worcester, Massachusetts

These Mastiffs are available for adoption close to Worcester, Massachusetts.
Photo of Silvio

Silvio

Mastiff Great Pyrenees

Male, Young
Shrewsbury, MA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
Silvio is the best boy. He is so loving, loves cuddles... and any kind of attention. He thinks hes small - still has puppy energy. He turned 3 in January 2026. I have no complaints with him whatsoever... rehoming him breaks our hearts, but he deserves better than the circumstances were facing. He needs room to stretch his legs and exercise on a regular basis. He loves playing in snow, he is so funny when he gets the zoomies lol. He is just the best!! He does so well at dogs parks, we take him almost every day. Gentle giant but protective over his family. He's not the biggest fan of strangers getting too close to us or our home but once they let him sniff & say hi its fine. I would love to be able to visit him occasionally. But he does need more than I can provide at this point so this must be done. You will love every second with him. He keeps life interesting thats for sure. He needs someone with time & energy.

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Photo of Hank

Hank

Mastiff Labrador Retriever

Male, Adult
Enfield, CT
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
To adopt please fill out an adoption application. Be sure to watch his video!  Hank is an 18 month old lab/mastiff mix who was rescued as a stray from the streets of Memphis.  Friendly, well socialized, never meets a stranger!  Good with other dogs, not cat tested.  Hank is very strong and active so he’s recommended for children 6 years and older. Very active outside, but he settles down quickly in the house. Crate trained and housebroken. Hank has a very distinctive “look” and is described by his foster mom as “a big goofball” and everyone who meets him just falls in love with him. Loves to be with his people.  Fair on the leash, we’re working on it. Rides great in the car.  Estimated DOB is 1-1-25.  Hank has a small cherry eye in his right eye and that will be repaired prior to adoption. Healthy and fully vetted, current on shots, neutered, weighs about 75 pounds.  AWESOME young lab/mastiff mix will make a wonderful companion (and jogging partner)  for an active family.. To adopt please fill out an adoption application.Contact us at reply@gooddogrescue.com  visit us at Good Dog RescueOctober 25, 2026, 11:45 am

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Photo of Mark

Mark

Mastiff Mixed Breed (Medium)

Male, 2 yrs 7 mos
Salem, NH
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
Hello there, I'm Mark! I may be young, but I've got a heart full of love to give. Every morning, I wake up excited for the day ahead. I love playing with my favorite chew toy, but what I really crave is a good game of fetch with a human friend. I'm a quick learner, too! I've already mastered 'sit' and 'stay', and I'm eager to learn more. I promise to be your loyal companion, always ready for an adventure or a cozy nap on the couch. I'm not just looking for a home, I'm looking for a family. Adopt me and let's create a lifetime of wonderful memories together.

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Photo of Alamo

Alamo

Mastiff Mixed Breed (Medium)

Male, 5 yrs 2 mos
Salem, NH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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Photo of Augustus

Augustus

American Staffordshire Terrier Mastiff

Male, 1 yr
Cumberland, RI
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Augustus, an 11-month-old brindle American Staffordshire Terrier mix with a touch of Mastiff — and ready to roll into his forever home! At 60 pounds, Augustus is a strapping young guy with a friendly spirit and loyal heart that's just waiting to bond with his forever family. He's got so much life ahead of him, and is eager to be your devoted companion through all of it. Come meet Augustus, he promises you won't regret making him part of your pack! Augustus comes to us from a shelter in Georgia. He is fully vetted and is here at The Hotel. Breeds are best guess. If you would like to meet/adopt this pup, please complete an application on our website: www.HotelforHomelessDogs.com Adoption Fee: $675.00

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Photo of Batman

Batman

American Staffordshire Terrier Mastiff

Male, 3 yrs
Cumberland, RI
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Batman, a 3-year-old black American Staffordshire Terrier mix with a little Mastiff in him, and he's a strapping 62-pound boy ready for his forever home! Batman is looking for someone who appreciates a gentle soul with a sweet nature. At his size, Batman is a magnificent companion for the right family who wants a loyal friend by their side. Come visit and see if you're a perfect match. Batman comes to us from a shelter in South Carolina. He is fully vetted and is here at The Hotel. Breeds are best guess. If you would like to meet/adopt this pup, please complete an application on our website: www.HotelforHomelessDogs.com Adoption Fee: $625.00

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Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Attleboro, MA Mastiff in Boston, MA Mastiff in Central Falls, RI Mastiff in Fitchburg, MA Mastiff in Franklin, MA Mastiff in Gardner, MA Mastiff in Leominster, MA Mastiff in Marlborough, MA Mastiff in Newton, MA Mastiff in Pawtucket, RI Mastiff in Providence, RI Mastiff in Waltham, MA Mastiff in Watertown, MA Mastiff in Woonsocket, RI

Related breeds in Worcester, Massachusetts

Bullmastiffs in Worcester, Massachusetts Neapolitan Mastiffs in Worcester, Massachusetts Saint Bernards in Worcester, Massachusetts

Mastiff shelters & rescues in Worcester, Massachusetts

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Worcester, Massachusetts. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

43.4 miles

Good Dog Rescue

Enfield, CT 06082

Pet Types: dogs

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Rescue

47.3 miles

Lucky's Legacy Rescue - NH Transport Stop

Salem, NH 03079

Pet Types: cats, dogs, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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