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Mastiff puppies and dogs in Worcester, Massachusetts

Looking for a Mastiff puppy or dog in Worcester, Massachusetts? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Worcester, Massachusetts Other pups in Worcester, Massachusetts Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Worcester, Massachusetts Mastiff shelters and rescues in Worcester, Massachusetts Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Worcester, Massachusetts

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Worcester, Massachusetts

These Mastiffs are available for adoption close to Worcester, Massachusetts.
We'll also keep you updated on Bruno PPJ's adoption status with email updates.
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Bruno PPJ

Mastiff

Male, Young
Union transport, CT
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website.Thank you for checking out our wonderful orphans. If you would like to find out more please email or call Diane at...diane@ulpr.org or 870-577-3744.   Please email us at  diane@ulpr.org  and request an application.Visit this organization's web site to see any additional information available about this pet.December 11, 2025, 3:57 pm

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We'll also keep you updated on Bruno PPJ's adoption status with email updates.
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Bruno PPJ

Mastiff

Male, Young
Rockingham transport, NH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website.Thank you for checking out our wonderful orphans. If you would like to find out more please email or call Diane at...diane@ulpr.org or 870-577-3744.   Please email us at  diane@ulpr.org  and request an application.Visit this organization's web site to see any additional information available about this pet.December 11, 2025, 3:57 pm

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We'll also keep you updated on Yeager's adoption status with email updates.
Photo of Yeager

Yeager

Mastiff American Pit Bull Terrier

Male, 7 yrs
Amherst, MA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Yeager! A devoted six-and-a-half-year-old Mastiff, American Pitbull Terrier, and Great Pyrenees mix currently living in Bethlehem, CT, whose heart is as big as his 70-pound frame. With a brindled fawn-colored coat that gleams in the sunlight and a soul that craves connection, Yeager is a lovable blend of strength, sweetness, and sensitivity. Yeager is the ultimate running partner and sunbathing enthusiast. Whether he's bounding beside you on a trail or sprawled out in a sunbeam with his paws in the air, he’s happiest just being near his people! Around kids, he shines—gentle and obedient, especially during mealtime when he’ll sit patiently with drool dripping in anticipation until he hears the magic word: “free!” He’s also crate-trained and house-trained, and though he does require a sturdy, escape-proof crate, he often chooses to snuggle up in it all on his own—it’s his safe little haven. Yeager’s heart is warm and full of affection, but it’s also a bit tender. After a traumatic veterinary experience a couple of years ago, he’s become more cautious around unfamiliar people. While he has never bitten anyone, he may growl or snap at the air when he feels unsafe. He’s working on his trust-building journey with the help of medication and positive reinforcement, but his next family should be patient and understanding—someone who will give him the calm, loving space he needs to settle in and thrive. He gets along famously with other dogs, having a blast with his canine cousins, and he’s an affectionate cuddle-bug to his human family! However, a home without cats or one experienced with slow introductions would be best due to his excitable play style. He’s also terrified of thunderstorms and fireworks, so a peaceful setting and a patient caregiver during loud events will help him feel secure. Yeager’s story is one of resilience, loyalty, and deep love. Are you the kind soul who can offer this beautiful boy the safety, companionship, and calm environment he needs to flourish in his next chapter? To learn more or welcome Yeager into your life, please reach out to adopt@joyfulpets.com!

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We'll also keep you updated on ALEX's adoption status with email updates.
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ALEX

Mastiff Chow Chow

Male, 2 yrs 7 mos
Boston, MA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
Meet Alex a lively, lovable pup with a big personality and an even bigger heart. Alex is currently on the road to recovery after TPLO surgery and is recovering from heartworm treatment. While he is on activity restriction for now, do not let that fool you, this boy has energy to spare and a playful spirit thats just waiting to shine once he has healed.Because of his high energy and temporary limitations, Alex will need a patient and experienced home that can help him channel that zest for life into brain games, enrichment activities, and plenty of mental stimulation. He is working hard on being a good boy during recovery, and he is making great progress with structure and support.When he has had his fill of mental fun and the zoomies are out of his system, Alex melts into a total cuddle bug. If you`re looking for a smart, spirited companion and you`re ready to help guide him through his healing journey, this squishy guy just might be your perfect match.

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We'll also keep you updated on Ardis's adoption status with email updates.
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Ardis

Mastiff

Female, Puppy
Boston, MA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered, Shots are up-to-date,
Story
**EVENT DEPOSIT PENDING**Adoptable in: MA, RI, NH, CT, and VTGood with dogs: YesGood with cats: YesGood with kids: Yes, dog savvy childrenCrate trained: YesHouse Trained: Mostly Ardis is a happy, sweet and good girl. She has the cutest little wrinkles next to her mouth when she smiles and her tongue is usually lolling. She has a medium energy level and would love a family who will share their adventures with her.Ardis is very excited when she meets other dogs and can’t wait to play with them. She would do best with other dogs who are as enthusiastic as she is about playtime! She has met a cat and backed away when it hissed at her, so would most likely coexist just fine with a cat sibling. Ardis has been around young kids and did well, but she is still perfecting her manners, so dog savvy kids would be best. She likes to play tug-of-war and wrestle with other dogs.Ardis will go in her crate happily and settles straight away. She is mostly house trained so long as her cues are not missed. She is learning basic commands and how to walk on a leash.Ardis is a playful girl with lots of love to give her new family! Is yours the one she’s been waiting for? Please Note: All dogs are posted on our website until they are officially adopted. This dog may have other interested adopters in line. If you are interested in adopting, please fill out an application on our website at www.lasthopek9.org. Last Hope K9 Rescue is licensed with the Massachusetts Department of Agricultural Resources (#0151).December 14, 2025, 12:53 am

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We'll also keep you updated on Ranger's adoption status with email updates.
Photo of Ranger

Ranger

Mastiff American Pit Bull Terrier

Male, Puppy
Chicopee, MA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Not good with kids, Not good with cats, Shots are up-to-date,
Story
Ranger is a 4 month old mixed breed pup. We have had him since he was 8 weeks old and are devastated that we are unable to keep him in our family. We have 2 young children, and are expecting another baby. Ranger is a very energetic puppy who loves attention. He is very mouthy and despite our best efforts we have not been able to curb this. It has become an issue with our kids and both of them are afraid of him because of the constant biting. Ranger is happy and friendly and not intentionally hurting, but it seems like he would be better suited for a home without small children. We are asking a rehoming fee of $200 to ensure Ranger is going to a suitable home where he will be well cared for. He is up to date on all shots. His last round of shots is due within the next few, and we will get these taken care of if he is still with us.

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Worcester, Massachusetts.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Worcester, Massachusetts

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Mastiff shelters & rescues in Worcester, Massachusetts

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Worcester, Massachusetts. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

30.4 miles

Pitter Pat Junction, CT transport

Union transport, CT 06076

Pet Types: dogs

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Rescue

33.5 miles

Pitter Pat Junction, NH transport

Rockingham transport, NH 03033

Pet Types: dogs

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Rescue

33.9 miles

Joyful Pets Rescue

Private Foster Homes, Amherst, MA 01002

Pet Types: cats, dogs, rabbits, small animals

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Shelter

34.3 miles

MSPCA - Boston Adoption Center

350 South Huntington Avenue, Boston, MA 02130

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

38.8 miles

Last Hope K9 Rescue

71 Commercial St, #184, Boston, MA 02113

Pet Types: dogs

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Rescue

47.3 miles

Lucky's Legacy Rescue - NH Transport Stop

Salem, MD 03079

Pet Types: cats, dogs, small animals

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Rescue

47.3 miles

Lucky Tails Rescue - VT transport

Salem, NH 03079

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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