Adopt
Rehome
Menu Hamburger Icon

Great Dane puppies and dogs in Mesa, Arizona

Looking for a Great Dane puppy or dog in Mesa, Arizona? Adopt a Pet can help you find an adorable Great Dane near you.

Picture of Great Dane

Learn More:

Adopt a Great Dane near you Great Dane in cities near Mesa, Arizona Other pups in Mesa, Arizona Search for a Great Dane puppy or dog near you Browse Great Dane puppies and dogs in nearby cities Browse related breeds in Mesa, Arizona Great Dane shelters and rescues in Mesa, Arizona Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Mesa, Arizona

These Great Danes are available in Mesa, Arizona.
Photo of Basil

Basil

Great Dane

Male, Adult
Mesa, AZ
Size
(when grown) -
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Basil is a six-year-old Great Dane with a sweet personality, a goofy streak, and plenty of love to give. He came into the care of Big Hearts for Big Breeds after his owner was no longer able to provide the care he needed, and his foster family is already discovering just how special this handsome boy is. Basil is wonderful in the house. He has had no potty accidents, isn't destructive, and listens beautifully to his foster family. He loves a good stuffy and enjoys playing fetch—although he's still working on that whole “bring it back” part! He is also completely fascinated by anything shiny, especially flashlights and other little flashes of light. His foster family says Basil seems to absolutely adore kids, and he has shown no interest in chasing lizards, rabbits, or other dogs. His compatibility with cats and small dogs is still being evaluated. Basil is doing well on his journey toward becoming an even more polished companion. He's okay on leash and shows plenty of potential to improve with continued practice. We're not yet sure how he does with extended crate time—he hasn't spent much time in one, although he hasn't seemed bothered by being crated for shorter periods. Basil is looking for a family who will appreciate his goofy charm, curious nature, and wonderfully good house manners. He's a big-hearted Great Dane who is ready for a fresh start and a forever home where he can be loved, included, and occasionally trusted to supervise the neighborhood.

Learn More

Small right facing arrow
Photo of Yuma

Yuma

Great Dane

Male, Adult
Mesa, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Yuma is a handsome 5-year-old Great Dane in the care of Big Hearts for Big Breeds, and he’s the kind of gentle soul who quietly wins your heart. Neutered, potty trained, and kennel trained, Yuma is a well-mannered boy who does well with other dogs and children. Yuma can be a bit shy at first, preferring to observe and take things in until he knows he’s safe. Once that trust is built, his sweetness shines through — a calm, affectionate Great Dane who simply wants a soft place to land and a family who will offer patience, kindness, and consistency. Yuma is ready for a loving home where he can finally relax and be cherished for the wonderful dog he is.

Learn More

Small right facing arrow
Photo of Cliff

Cliff

Great Dane

Male, Young
Mesa, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Cliff is a handsome 1½-year-old fawn Great Dane who recently joined the Big Hearts for Big Breeds family in our New Mexico foster program. This sweet young boy is settling in beautifully and is ready to find a forever home where he can continue to thrive. Like many young Danes, Cliff is still growing into his giant frame and doesn't always realize just how big he is! Because of his enthusiastic nature, he would do best with children ages 8 and up who can comfortably enjoy life with a lovable oversized companion. Cliff is potty trained, kennel trained, and has excellent house manners. He gets along well with other dogs and seems to especially enjoy the company of female dogs. He's also cat-friendly, making him a wonderful candidate for many multi-pet households. With his affectionate personality, handsome good looks, and sweet disposition, Cliff is everything people love about young Great Danes. He's looking for a family ready to embrace the fun, loyalty, and occasional goofy moments that come with sharing life with a gentle giant. If you're searching for a well-mannered young Great Dane who's already off to a fantastic start, Cliff may be the perfect addition to your family. Big Hearts for Big Breeds can't wait to help this wonderful boy find the forever home he deserves.

Learn More

Small right facing arrow
Photo of Hazel

Hazel

Great Dane

Female, Senior
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Hazel is an approximately 9–10-year-old spayed female Great Dane who has officially earned the right to take life at her own pace. Hazel came into rescue alongside Granite after their owner passed away. Now in the care of Big Hearts for Big Breeds, this sweet senior girl is looking for a comfortable forever home where she can soak up the sunshine, enjoy her people, and simply be loved. Hazel is wonderful with people and kids, and if you ask her, the perfect day involves finding the sunniest spot in the yard and settling in for a good, long nap. She has a wonderfully easygoing personality and isn't looking for a busy schedule—just a soft place to rest and people who appreciate a laid-back Great Dane. Hazel was previously described as not being good with other dogs, but her history tells us there may be more to the story. She lived contentedly with another male Great Dane in her previous home and has already had successful, slow introductions with a foster dog in rescue. We believe Hazel may simply need thoughtful introductions and the companionship of calm, appropriately matched large dogs. As always, we'll continue to learn more about her and set her up for success. At this stage in life, Hazel deserves a home that understands that senior dogs have a special kind of magic. She has so much love left to give and would be perfectly happy spending her golden years lounging in the sunshine and keeping her favorite people company. If you're looking for a sweet, sun-loving Great Dane who has mastered the art of relaxing, Hazel might be your perfect match. Big Hearts for Big Breeds can't wait to help this beautiful girl find the peaceful, loving forever home she deserves.

Learn More

Small right facing arrow
Special Needs
Photo of Reef

Reef

Great Dane

Male, Adult
Mesa, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with cats, Needs special attention, House-trained, Spayed or Neutered,
Story
Reef is a three-year-old neutered male Great Dane with a striking merle coat and a handsome presence to match. Now in the care of Big Hearts for Big Breeds, this boy is looking for a forever home that understands his needs and can provide the right environment for him to thrive. Reef is kennel trained, potty trained, and leash trained, and he rides well in the car. He has a wonderful foundation of good manners and is ready for a family that will continue to provide consistency, structure, and plenty of love. Reef is looking for a very specific canine setup. He is not a match for cats, small dogs, or male dogs. He would be perfectly happy as the only dog in the home, or he may do well with one large-breed female dog with a thoughtful introduction and appropriate supervision. He would also do best with older children, ages 14 and up. Finding the right match is especially important for Reef, and we believe there is a family out there who will appreciate exactly what makes him special. If you're an experienced large-breed home looking for a handsome Great Dane companion, Reef may be the boy you've been waiting for. Big Hearts for Big Breeds is excited to help him find the forever home that's just right for him.

Learn More

Small right facing arrow
Photo of Granite

Granite

Great Dane

Male, Adult
Mesa, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Granite is a handsome four-year-old neutered male Great Dane with a striking merle coat and a heart as impressive as his size. Now in the care of Big Hearts for Big Breeds, Granite is looking for a forever home after experiencing the heartbreaking loss of his owner. Granite came into rescue alongside Hazel after their owner passed away. While losing the person they knew and loved has been a major change, both dogs are now safe, supported, and getting the chance to begin a new chapter. Granite is ready to find a family who will give him the stability, love, and companionship he deserves. This sweet boy is wonderful with people, great with kids, and gets along well with other dogs. He is kennel trained and comes with an especially impressive training foundation—Granite is also trained to an e-collar/beeper collar. He's a smart boy who has already learned valuable skills and is ready for a family that will continue to build on that foundation. Granite is the kind of Great Dane who has so much to offer: handsome, loving, social, and ready to be someone's loyal companion. After losing his family through no fault of his own, he's hoping his next chapter will be the one that lasts forever. If you're looking for a well-trained, affectionate Great Dane with a wonderful foundation and a big heart, Granite may be the perfect match. Big Hearts for Big Breeds can't wait to help this deserving boy find the loving forever home he deserves.

Learn More

Small right facing arrow

Or, how about these Great Danes in cities near Mesa, Arizona

These Great Danes are available for adoption close to Mesa, Arizona.
Photo of Basil

Basil

Great Dane

Male, Adult
Mesa, AZ
Size
(when grown) -
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Basil is a six-year-old Great Dane with a sweet personality, a goofy streak, and plenty of love to give. He came into the care of Big Hearts for Big Breeds after his owner was no longer able to provide the care he needed, and his foster family is already discovering just how special this handsome boy is. Basil is wonderful in the house. He has had no potty accidents, isn't destructive, and listens beautifully to his foster family. He loves a good stuffy and enjoys playing fetch—although he's still working on that whole “bring it back” part! He is also completely fascinated by anything shiny, especially flashlights and other little flashes of light. His foster family says Basil seems to absolutely adore kids, and he has shown no interest in chasing lizards, rabbits, or other dogs. His compatibility with cats and small dogs is still being evaluated. Basil is doing well on his journey toward becoming an even more polished companion. He's okay on leash and shows plenty of potential to improve with continued practice. We're not yet sure how he does with extended crate time—he hasn't spent much time in one, although he hasn't seemed bothered by being crated for shorter periods. Basil is looking for a family who will appreciate his goofy charm, curious nature, and wonderfully good house manners. He's a big-hearted Great Dane who is ready for a fresh start and a forever home where he can be loved, included, and occasionally trusted to supervise the neighborhood.

Learn More

Small right facing arrow
Photo of Yuma

Yuma

Great Dane

Male, Adult
Mesa, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Yuma is a handsome 5-year-old Great Dane in the care of Big Hearts for Big Breeds, and he’s the kind of gentle soul who quietly wins your heart. Neutered, potty trained, and kennel trained, Yuma is a well-mannered boy who does well with other dogs and children. Yuma can be a bit shy at first, preferring to observe and take things in until he knows he’s safe. Once that trust is built, his sweetness shines through — a calm, affectionate Great Dane who simply wants a soft place to land and a family who will offer patience, kindness, and consistency. Yuma is ready for a loving home where he can finally relax and be cherished for the wonderful dog he is.

Learn More

Small right facing arrow
Photo of Cliff

Cliff

Great Dane

Male, Young
Mesa, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Cliff is a handsome 1½-year-old fawn Great Dane who recently joined the Big Hearts for Big Breeds family in our New Mexico foster program. This sweet young boy is settling in beautifully and is ready to find a forever home where he can continue to thrive. Like many young Danes, Cliff is still growing into his giant frame and doesn't always realize just how big he is! Because of his enthusiastic nature, he would do best with children ages 8 and up who can comfortably enjoy life with a lovable oversized companion. Cliff is potty trained, kennel trained, and has excellent house manners. He gets along well with other dogs and seems to especially enjoy the company of female dogs. He's also cat-friendly, making him a wonderful candidate for many multi-pet households. With his affectionate personality, handsome good looks, and sweet disposition, Cliff is everything people love about young Great Danes. He's looking for a family ready to embrace the fun, loyalty, and occasional goofy moments that come with sharing life with a gentle giant. If you're searching for a well-mannered young Great Dane who's already off to a fantastic start, Cliff may be the perfect addition to your family. Big Hearts for Big Breeds can't wait to help this wonderful boy find the forever home he deserves.

Learn More

Small right facing arrow
Photo of Hazel

Hazel

Great Dane

Female, Senior
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Hazel is an approximately 9–10-year-old spayed female Great Dane who has officially earned the right to take life at her own pace. Hazel came into rescue alongside Granite after their owner passed away. Now in the care of Big Hearts for Big Breeds, this sweet senior girl is looking for a comfortable forever home where she can soak up the sunshine, enjoy her people, and simply be loved. Hazel is wonderful with people and kids, and if you ask her, the perfect day involves finding the sunniest spot in the yard and settling in for a good, long nap. She has a wonderfully easygoing personality and isn't looking for a busy schedule—just a soft place to rest and people who appreciate a laid-back Great Dane. Hazel was previously described as not being good with other dogs, but her history tells us there may be more to the story. She lived contentedly with another male Great Dane in her previous home and has already had successful, slow introductions with a foster dog in rescue. We believe Hazel may simply need thoughtful introductions and the companionship of calm, appropriately matched large dogs. As always, we'll continue to learn more about her and set her up for success. At this stage in life, Hazel deserves a home that understands that senior dogs have a special kind of magic. She has so much love left to give and would be perfectly happy spending her golden years lounging in the sunshine and keeping her favorite people company. If you're looking for a sweet, sun-loving Great Dane who has mastered the art of relaxing, Hazel might be your perfect match. Big Hearts for Big Breeds can't wait to help this beautiful girl find the peaceful, loving forever home she deserves.

Learn More

Small right facing arrow
Special Needs
Photo of Reef

Reef

Great Dane

Male, Adult
Mesa, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with cats, Needs special attention, House-trained, Spayed or Neutered,
Story
Reef is a three-year-old neutered male Great Dane with a striking merle coat and a handsome presence to match. Now in the care of Big Hearts for Big Breeds, this boy is looking for a forever home that understands his needs and can provide the right environment for him to thrive. Reef is kennel trained, potty trained, and leash trained, and he rides well in the car. He has a wonderful foundation of good manners and is ready for a family that will continue to provide consistency, structure, and plenty of love. Reef is looking for a very specific canine setup. He is not a match for cats, small dogs, or male dogs. He would be perfectly happy as the only dog in the home, or he may do well with one large-breed female dog with a thoughtful introduction and appropriate supervision. He would also do best with older children, ages 14 and up. Finding the right match is especially important for Reef, and we believe there is a family out there who will appreciate exactly what makes him special. If you're an experienced large-breed home looking for a handsome Great Dane companion, Reef may be the boy you've been waiting for. Big Hearts for Big Breeds is excited to help him find the forever home that's just right for him.

Learn More

Small right facing arrow
Photo of Granite

Granite

Great Dane

Male, Adult
Mesa, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Granite is a handsome four-year-old neutered male Great Dane with a striking merle coat and a heart as impressive as his size. Now in the care of Big Hearts for Big Breeds, Granite is looking for a forever home after experiencing the heartbreaking loss of his owner. Granite came into rescue alongside Hazel after their owner passed away. While losing the person they knew and loved has been a major change, both dogs are now safe, supported, and getting the chance to begin a new chapter. Granite is ready to find a family who will give him the stability, love, and companionship he deserves. This sweet boy is wonderful with people, great with kids, and gets along well with other dogs. He is kennel trained and comes with an especially impressive training foundation—Granite is also trained to an e-collar/beeper collar. He's a smart boy who has already learned valuable skills and is ready for a family that will continue to build on that foundation. Granite is the kind of Great Dane who has so much to offer: handsome, loving, social, and ready to be someone's loyal companion. After losing his family through no fault of his own, he's hoping his next chapter will be the one that lasts forever. If you're looking for a well-trained, affectionate Great Dane with a wonderful foundation and a big heart, Granite may be the perfect match. Big Hearts for Big Breeds can't wait to help this deserving boy find the loving forever home he deserves.

Learn More

Small right facing arrow

These pups are in Mesa, Arizona too!

Below are our newest added Great Danes available for adoption in Mesa, Arizona. To see more adoptable Great Danes in Mesa, Arizona, use the search tool below to enter specific criteria!
Photo of SPYRO

SPYRO

Anatolian Shepherd Husky

Male, 2 yrs 3 mos
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-

Learn More

Small right facing arrow
Photo of CAPONE

CAPONE

Anatolian Shepherd

Male, 3 yrs 8 mos
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-

Learn More

Small right facing arrow
Photo of Ocean

Ocean

Bullmastiff

Female, Adult
Mesa, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered,
Story
Ocean is a beautiful four-year-old brindle Bullmastiff mix with a big heart and a loyal spirit. Now in the care of Big Hearts for Big Breeds, this lovely girl is looking for a forever home that understands her protective nature and will appreciate all the love she has to give. Ocean is wonderful with both big and little dogs and enjoys having canine companions around. Her compatibility with cats is currently unknown. She doesn't need a kennel and has done well without one, making her a great fit for a home where she can simply be part of the family. Ocean can be protective of her home when strangers arrive, so she will do best with an experienced large-breed adopter who understands the importance of structure, confidence, and thoughtful introductions. She would also be happiest with older children, ages 14 and up. Once Ocean knows you're her person, you'll have a devoted companion who is ready to be by your side. She's looking for a family who will respect her protective instincts, give her clear guidance, and allow her the time she needs to feel comfortable with new people. If you're an experienced large-breed home looking for a loyal, beautiful Bullmastiff mix with a heart of gold, Ocean may be your girl. Big Hearts for Big Breeds can't wait to help her find the forever home where she can feel safe, loved, and truly belong.

Learn More

Small right facing arrow

Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Mesa, Arizona.

    an arrow icon
  • Ashburn, VA
  • Ashburn, VA

Sorry, we can’t find that location! Please try again.

    Age
    an arrow icon

Great Dane puppies and dogs in nearby cities

Great Dane Puppies near me Great Dane in Apache Junction, AZ Great Dane in Avondale, AZ Great Dane in Cave Creek, AZ Great Dane in Chandler, AZ Great Dane in El Mirage, AZ Great Dane in Fountain Hills, AZ Great Dane in Gilbert, AZ Great Dane in Glendale, AZ Great Dane in Goodyear, AZ Great Dane in Guadalupe, AZ Great Dane in Litchfield Park, AZ Great Dane in Maricopa, AZ Great Dane in Paradise Valley, AZ Great Dane in Peoria, AZ Great Dane in Phoenix, AZ Great Dane in Queen Creek, AZ Great Dane in Scottsdale, AZ Great Dane in Surprise, AZ Great Dane in Tempe, AZ Great Dane in Tolleson, AZ

Related breeds in Mesa, Arizona

Anatolian Shepherds in Mesa, Arizona Bullmastiffs in Mesa, Arizona Irish Wolfhounds in Mesa, Arizona

Great Dane shelters & rescues in Mesa, Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Mesa, Arizona. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

3.6 miles

Big Hearts for Big Breeds

Mesa, AZ 85202

Pet Types: dogs

More an arrow icon

Rescue

12 miles

Bug to the Rescue

Scottsdale, AZ 85260

Pet Types: dogs

More an arrow icon

Rescue

24.4 miles

Regal Dane Rescue

4410 W UNION HILLS DR STE 7-187, GLENDALE, AZ 85308

Pet Types: dogs

More an arrow icon

Shelter

26.3 miles

Barbs Dog Rescue

8028 W Thunderbird, Peoria, AZ 85381

Pet Types: dogs

More an arrow icon

Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

magnifying glass with cat and dog

Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

clipboard with list

Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

Learn More an arrow icon