Great Dane puppies and dogs in Mechanicsburg, Pennsylvania

PLEASE NOTE! Unless stated otherwise, our dogs and puppies are located in Arkansas, and transported to the north/northeast once adopted. We do occasionally have dogs/puppies placed in foster homes in the north/northeast. In the cases where the pet is somewhere other than Arkansas, it will be noted beside the name of the pet.12/5/25 Adoption fee waived! Needs a home or new foster! In Arkansas, but can transport to New England area. Tango is a big, young Great Dane mix. He is a wonderful dog with a gentle demeanor. He is amazing with kids, as well as other dogs. He was adopted from us as a young puppy, and his family absolutely adored him. His family, which included a little boy around 4-5 years old, did a fantastic job raising him. They trained him and gave him everything he needed to be the best boy. Sadly, the little boy and the dad of the family developed a severe allergy to dogs. It was so bad that dad ended up in the hospital. So they had to surrender Tango back to us. Since then he has been in a foster home. He's OK, but hes confused and sad and is experiencing some anxiety, understandably. He just wants to be with people, but in his current foster situation he has to be crated a lot of the time. This is hard on him because he did not have to be crated in his former home. He isn't destructive and is honestly just such a good dog. But due to other dogs in the foster home, this is the best we can do. Tango really needs a home of his own where he can devote himself to truly loving his people again, and can be part of the family. He is 2 years old and weighs about 95 lbs. But he has been taught from early on to be gentle. His favorite person in the world was his 'little brother' and he was so good with him. His heart is broken right now because he doesn't understand why he's not with his family any more. Please help us heal his heart. He needs a new foster home where he can be allowed more freedom in the home, or he needs an adopter who will love him and help him heal from this heart break. We will waive his adoption fee for the right home. Please share. Located in Arkansas. He can be adopted locally, but transport is available to the New England area as well. Adopter must be able to pick up or arrange for someone to pick up for them in PA, NY, or CT on Saturdays. To apply to adopt Tango, please click the link. https://form.jotform.com/212690945239059 email apps.aasr@gmail.com with any questions. Visit this organization's web site to see any additional information available about this pet.Our typical adoption fee for puppies younger than 6 months old is $400, and for older puppies and adults, the usual fee is $350. This includes microchip, spay/neuter,  up to date on age appropriate vaccinations, dewormings, flea/tick treatment, and heartworm test (if over 6 months old) as well as heartworm treatment if they test positive. There is a transport fee of $150 per dog, depending on the transporter. We use Pack Leaders Rescue Dog Transport most often, but also use Hearts Transport as well on occasion. Please visit our Facebook page too! https://www.facebook.com/adoptastrayrescueorg For more info regarding adopting, email apps.aasr@gmail.com Thank you for considering one of our rescue babies!December 6, 2025, 4:51 am

You can fill out an adoption application online on our official website. Fill out an Adoption Application Since coming to MTM, Rajah has been adopted twice, and returned within a month each time. Why? She’s a big, strong, and playful girl, who came into rescue because her owner died, and her owner’s next of kin kept her outside for 2 years before surrendering her to rescue in January 2021. In those 2 years, she had minimal training and human interaction, and she became infected with heartworm. MTM provided heartworm treatment and she is now negative. Rajah’s previous adopters expected too much, too soon. The first adopters allowed their cat in immediate proximity within the first hour, and Rajah chased. Days later, it wasn’t any better. The second adopter had no other pets, and no children at home. Rajah was adjusting well to the routine and the long walks and all the attention. But, when an adult child and dog visited, Rajah got protective, so she was returned. Her perfect home would have a confident and patient owner, no children, no other animals, and a yard that is fenced in with a physical fence.  Rajah could potentially have a K9 brother or sister as long as his/her demeanor was calm and not overly exuberant or aggressive and they were introduced properly, with decompression techniques used. Rajah needs time and consistency to learn her people are trustworthy. She doesn’t have good social skills with dogs. She chases cats and other small animals. She has been with the same fosterer since April 2021. Her fosterer has other dogs, and goats. Rajah is kept separated from the other animals, and her fosterer feels Rajah doesn’t get enough time with her. Her fosterer describes Rajah as a loving, bouncy Great Dane, a "picture-perfect dog that is just beyond beautiful. Her soul and spirit are truly a rare blessing." She deserves a home where she can enjoy her own space and her own people. Rajah knows basic obedience, just needs to be reminded. She pulls at times but also knows how to walk at a heel position. She loves her zoomies but then will get excited and will jump up to face greet. Putting her in a sit and giving a calm chest rub will calm her back down. Rajah is located in Knoxville, MD. She rides great in the car. She has no issues with people approaching, but she will bark at other dogs. Going to the vet hasn’t been an issue. Grooming; she is fine with nails trims, brushing, etc. She is fine by herself, so she can be left alone while someone works. Likes: Rajah loves having her face petted and leaning in for a Dane hug. She is so attentive and eager to please. She does well in a crate, but she will sing to you if she needs a potty break, a hug or attention. Dislikes: Strangers, dogs barking at her, unpredictable people or activity Personality: Rajah is playful and loving. Her facial expression is so soft. She just wants to get and give love. Energy level: Rajah is able to be calm in a crate, but when loose she is high energy. She loves her zoomies so would do best in a fenced yard. She runs the fence barking at the goats, and the other dogs. Favorite activities: Zoomies and hugs. Good with: Calm, confident and predictable adult humans, and positive training. She likes to please. Not good with: Energetic or loud dogs or cats. She is insecure, so is not trustworthy with children. Housetrained: Yes. Crate trained: Yes. Challenges: Rajah will need to have her obedience training refreshed. She is calmest in a home with a confident owner or she will take control. She does not have good dog-to-dog social skills and she chases cats, so would do best in a home with no other pets. She has done well with calm K9's, so that is a possibility and can be explored in discussion with her current foster. Any Medical issues? Rajah is now heartworm negative! Rajah would thrive in an experienced Great Dane home that understands the importance of ongoing training to build Rajah's confidence. Being an only dog would give her the attention and the time she wants and needs to become a happy-go-lucky Dane. A fenced yard would give her the thrill of the zoomies that she so loves. Rajah may be seven years old, but she isn’t ready to slow down. A typical Dane, she will enjoy going for a walk just as much as a nap. Meeting this girl will bring a joy to your life that only a Great Dane can bring.Click here to watch a video of Rajah.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. &#226&#128&#139Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   August 24, 2025, 11:31 am

You can fill out an adoption application online on our official website. Fill out an Adoption Application Are you old enough to remember Mr. Ed the talking horse? Finley isn’t fluent in English like Mr. Ed, but he is a talker. His greeting isn’t just a happy face and wagging tail, it’s also a “wooooo” that is sure to make you smile. HISTORY: Finley was dumped at an overcrowded shelter in Kentucky and put into a crate too small for him to stand up in. A local foster-based rescue pulled him. He spent two months with his foster family while they got to know him and to put on some needed weight then they contacted Mastiffs to Mutts Rescue to find him the perfect home. Finley is a one-year-old male Great Dane mix. Due to his age, he is not neutered and will not be for another six months, minimum. PERSONALITY: Finley is at the most wonderful age; old enough to be potty trained and young enough to be a puppy. A 115-pound puppy. He is happy, calm, friendly, playful and cuddly. He easily goes into his crate to eat and sleep but prefers to be with his housemates, both canine and human. His eyes are expressive, and his “wooooo” will clear up any confusion on how he is feeling. You’ll smile every time you hear it which will make his tail way even harder. FAVORITE ACTIVITIES: Finley enjoys playing with his Great Dane foster sister followed by a relaxing antler gnawing session or a nap. He really enjoys people and is very curious about anything that’s happening around him. Butt scratches, ear rubs and chilling with his family are also highlights of his day. MEDICAL ISSUES: Finley will need to be neutered at 18 months or after. WHAT WOULD BE THE BEST KIND OF HOME: Finley looks like an adult, but he is a puppy and needs to be treated and trained as a puppy. He does not have social graces around other animals, so any animals already in the house will need to be comfortable with a large puppy. As for Finley, he loves to meet new dogs and will immediately ask them to play. Because of his calm, friendly nature Finley would be good for a family new to having a giant breed dog in their home. He’d love to have children or dogs to play with, but he’d be just as happy with adults.Click here to watch a video of Finley.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. &#226&#128&#139Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   December 6, 2025, 12:39 pm

Current Location: Parsonsburg, MD Hello! My name is Black Beauty! I'm coming to OPH on 12/10. Please check back soon for updates on my personality, and to see adorable new photos. I’m looking for my forever family! Is that with you? If so please click “apply for adoption” or submit an application through the Adopt tab. Let’s get our family started!

You can fill out an adoption application online on our official website.All of the animals posted on our site have been temperament tested. While not all are in the immediate area, once we have processed and approved your application, we will move the dog to our adoptive area for you to meet, greet and hopefully adopt. Sometimes we will have more than one application on a dog. That does not mean it automatically goes to another family but you should be aware of the fact that until you are approved and set up for the meet/greet.. the dog could get adopted by another applicant.Dolly has large Great Dane genes grafted onto a somewhat smaller body. Not that anyone would ever call her small, but you would say she's a manageable size, which is perfect. If you love the Dane look, but aren't sure you could handle a full size model, we have Dolly waiting for you. She is currently only 60 lbs., but that is a bit deceiving, as she is very underweight. We would like to see at least 15 lbs. more on her ribs and we are working on it. She is now getting top quality groceries, something she has never had before. Still a young dog, at only about 2 years old, she is in the process of learning about how to deal with the world around her and she is learning fast. Her foster has some comments to help you understand this 'dog-in-progress. 'She’s nervous around new people and things. She does warm up after a bit. Her initial reaction to people that she doesn’t know is to low growl. She is trying to tell everyone to give her a moment to process the new information. I don’t recommend a house with cats or small animals. She’ tries to chase down all the birds,  and squirrels when we’re outside. I’m fairly confident her life prior to rescue wasn’t a good one. It's heartbreaking seeing a good dog trying to cope with a world she was never shown. UPDATE:I have had her for a month now, and she is learning! I took her to the vet today, and while she was nervous, she did not growl. So there has been improvement on that aspect. She wasn’t super outgoing and wanting everyone’s attention, so definitely stand by the slower to warm up to strangers. I highly suspect she’s been abused. She is highly intelligent and learns new things really fast.  She really has the potential to be an excellent dog, and wants to be loved and please her person. MORE UPDATE: Since being here at my house over a month now I have some new insights into her. She is not dog friendly with all dogs.  She's OK with my male dog, but not so happy with my female.  I've been working on getting her to ignore people on walks and she's doing better. She doesn't like it if strangers get to close when we are out.  In the yard. she's definitely going to need at least a 6 foot fence to keep her safely secured.  I will say, she is house trained and does let you know when she needs to go out. She also does very well in her kennel. She is very smart, and can learn things pretty quickly. She has all her shots and is ready and waiting for the person or family who like bigger dogs, but aren't ready for an actual Goliath. Dolly is a good girl! She is hoping you will want to help her be a good dog and come for her soon.   If you are interested in Dolly, please fill out an application at: https://reachoutrescue.rescuegroups.org/forms/form?formid=4588    Or contact: rorrcanine@gmail.com   *** Click here to sponsor this dog! ***Visit this organization's web site to see any additional information available about this pet.December 8, 2025, 10:33 pm