Adopt

Great Dane puppies and dogs in York, Pennsylvania

Looking for a Great Dane puppy or dog in York, Pennsylvania? Adopt a Pet can help you find an adorable Great Dane near you.

Picture of Great Dane

Adopt a Great Dane near you in York, Pennsylvania

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near York, Pennsylvania

These Great Danes are available for adoption close to York, Pennsylvania.
Photo of Odette

Odette

Great Dane

Female, 2 yrs
Lancaster, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Here is Odette! This younger gal is here as a stray and ready for her next adventure! She is a very large and enthusiastically energetic pup with lots to say. She would thrive in an active household and would benefit from some basic obedience training. She doesn`t like to be left alone and would not be happy with someone who works a 9-5. At the very least she needs an adopter who can help her work through her separation anxiety. She also can get overwhelmed with the hustle and bustle of city apartment living and would prefer a quieter suburban or rural setting. She is open to living with children who can handle her energetic nature. She could potentially get along with another dog as long as they are tolerant of her playfulness. We are not aware of how she will do around cats. We understand she has a number of stipulations but we want her to thrive in her ideal furever home. And she is so worth it for all the smiles, love, and companionship she will share. If you have space in your home and are ready for an adventure come meet Odette!---If you are interested in adopting, please come prepared --bring a photo ID, proof of address, and everyone in the home including resident dogs with vaccination history. We are open daily 12-6pm.---The Pennsylvania SPCA - Lancaster Center848 S. Prince St. Lancaster PA 17603Kennel #16516717-917-6979lancaster@pspca.org
Photo of Sol

Sol

Great Dane

Male, Puppy
Spring Grove, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Shots are up-to-date,
Story
The story of Sol. He is about one year old. He has been very loved, trained and has grown up with his bother Manny. Our daughter rescued these boys from an unwanted situation. Unfortunately our daughter has become ill and unable to give them the quality of life they deserve. We are currently fostering them however we have 3 doodles and retired and unable to give them the attention they deserve. His has a lovely personality. Calm, cool and collected! Doppy , funny, snuggly, obedient and quite lazy. We would love the boys to be placed together but we understand that may not be the case. I’m sure Sol would be a wonderful addition for a right family.
Photo of Manny

Manny

Great Dane

Male, Puppy
Spring Grove, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Shots are up-to-date,
Story
The story of Manny. He is one year old and raised with his brother Sol. He was rescued by my daughter from an unwanted home. She has become very ill and unable to care for Manny and his brother. We are currently fostering them til they are placed with a proper pet parent. Manny is trained, sweet, personable, obedient, compassionate, affectionate, and definitely a team player. we would prefer the boys be adopted together, but we know the likelihood of that may not be possible. Manny would make a great addition to the right family.
Photo of Celeste

Celeste

Great Dane Catahoula Leopard Dog

Female, Adult
Harrisburg, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE NOTE! Unless stated otherwise, our dogs and puppies are located in Arkansas, and transported to the north/northeast once adopted. We do occasionally have dogs/puppies placed in foster homes in the north/northeast. In the cases where the pet is somewhere other than Arkansas, it will be noted beside the name of the pet.9/20 Still in need!!  9/4/26 WAIVED ADOPTION FEE!! Celeste cant stay in rescue forever, she really needs to find her forever home! Shes holding up a spot for others in need, plus she deserves a home of her own. PLEASE SHARE!!She needs to be the only dog in the home. She can go for walks and such and pass by other dogs, but cant live with other dogs. It is VERY hard to find homes for dogs who need to be the only pet in the home. She loves people!! She is all the things. A stunning beauty, heartwarmingly affectionate, and playfully mischievous in the most innocent way. She follows some basic commands such as sit, is house trained, and very food motivated. We do not know her breed. We only have her looks/size to go by. Great Dane, Catahoula, Lab? We dont know for sure but we do know shes a beauty!Shes about 80 pounds, one and a half years old. We have so many more pictures and videos but can only put 4 on this website. Please email us or visit our Facebook to see more pics and videos. Link to our facebook:https://www.facebook.com/adoptastrayrescueorg?mibextid=wwXIfr&mibextid=wwXIfrShe is spayed, vaccinated, microchipped, and is current on flea/tick/heartworm prevention. Located in New England.  To apply, please fill out the adoption app: https://form.jotform.com/212690945239059email apps.aasr@gmail.com with any questions.Visit this organization's web site to see any additional information available about this pet.Our typical adoption fee for puppies younger than 6 months old is $400, and for older puppies and adults, the usual fee is $350. This includes microchip, spay/neuter,  up to date on age appropriate vaccinations, dewormings, flea/tick treatment, and heartworm test (if over 6 months old) as well as heartworm treatment if they test positive. There is a transport fee of $150 per dog, depending on the transporter. We use Pack Leaders Rescue Dog Transport most often, but also use Hearts Transport as well on occasion. Please visit our Facebook page too! https://www.facebook.com/adoptastrayrescueorg For more info regarding adopting, email apps.aasr@gmail.com Thank you for considering one of our rescue babies!September 21, 2026, 7:47 am
Photo of Gelo

Gelo

Great Dane

Male, Young
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Certified good boy in training, professional smuggle seeker. Meet Mr. New-Kid-On-The-Block Gelo! He's sweet, loves people, and is still figuring out this whole "pet life" thing. Big wins so far: Kid approved ✅ Great with kids Road trip buddy ✅ Rode in the truck like a gentleman, chilling in the back with my daughter. Dog-friendly-ish ✅ Says hi politely to most pups. Got a little side eye for a recently neutered Great Pyrenees that stopped by, but who can blame him? Gelo is still working on his leash skills because squirrel! and learning that sidewalks aren't a buffet of smells. Kennel manners? Leveling up fast. He’s using the dog door like a pro. Medically? Gelo is all good. He just finished his antibiotics, so he's fresh, healthy, and ready to roll. Above all, this dude is a total love bug. Pets, scratches, attention -- Gelo's here for all of it. Gelo is new, so we're still. unlocking new levels of his personality, but early reviews say: 5 stars, would snuggle again. Looking for a sweet, goofy co-pilot who's ready to learn and love? Gelo's your guy. Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   September 22, 2026, 10:43 pm
Photo of Journey

Journey

Great Dane

Female, Adult
Mechanicsburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Good with dogs, Not good with cats, Spayed or Neutered,
Story
Journey's UPDATE 9/12/26:  Journey is a BIG Happy, Lovable and Goofy Great Dane. She is affectionate, playful and as it turns out GREAT with other dogs! (was not when arrived at MP)  She is younger than initially felt to be, now best guess is 1 1/2 - 2 years. She has gained all her needed weight and her skin sores have healed. She has made a FULL recovery.  This special gal is happy and energetic loving life. How about it, ready for a new best friend? Journey wants to continue her Journey with you!  See her full story since arrival to MP below.  Journey's story didn't start out easy. Found as a stray in the South, she ended up in a high-kill shelter. She was heartbreakingly thin, covered in open wounds, and had clearly been through more than any dog should. Believed to be around 3 years old—or perhaps even younger—Journey desperately needed someone to give her a chance. That chance came when Molly's Place stepped in. They brought her to Pennsylvania and began the journey that inspired her name. With patience, expert care, and lots of love, Journey has made an incredible transformation. Today, Journey is the stunning 108# Great Dane she was always meant to be! The days of being skin and bones are behind her. After a month of healing, her wounds have completely recovered, she's filled out beautifully, and her joyful spirit shines brighter every day. Journey is a happy, HAPPY, energetic, and affectionate girl who is ready to find the loving family she's been waiting for. She gets along well with adults and no kids due to her enthusiastic Great Dane body and tail has a mind of its own!  She is wanting all your love and attention, so she does have to be the only animal in the home as well. Her house-training status is currently unknown. Since found as a stray, a 6 ft fenced yard is required.  Journey has overcome so much and is more than ready for the next chapter of her life. Could that chapter be with you? Applications are now being accepted, so don't wait too long. Journey is ready to leap into your heart—and maybe even your lap—and finally find the forever home she deserves. Kennel License #7198 To submit an adoption application, visit mollysplacerescue.org. Fill the form out completely, print, scan and email back to mollysplace@verizon.net. You must obtain pre-approval prior to visiting the dog or cat. Adoptions fees include the following:    spay/neuter surgery,  microchip and registration,  age appropriate vaccinations,  initial dewormings,  Activyl for fleas,  tested for FeLV and FIV (cats only),  bubble bath prior to going home (dogs only) WE do not "HOLD" animals without an approved application and a non-refundable/non-transferable paid adoption fee.  Adoptions are on a first come, first serve basis.  We can not send extra pictures.  WE do not ship, you must pick up the pet.  Kitties must be transported in a secure cat carrier.   Pooches require a "martingale" collar and a non-retractable leash. Visit this organization's web site to see any additional information available about this pet.September 23, 2026, 4:28 pm

These pups are in York, Pennsylvania too!

Below are our newest added Great Danes available for adoption in York, Pennsylvania. To see more adoptable Great Danes in York, Pennsylvania, use the search tool below to enter specific criteria!
Photo of Jackson *Adoption Pending*

Jackson *Adoption Pending*

Bullmastiff Boxer

Male, 2 yrs 5 mos
York, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
Currently fostered in: Brooklyn Park, MD 💙Meet Jackson!💙 Some dogs are content with minimal human interaction. Some dogs enjoy their personal space. Jackson? He has never heard of either of those things. This big, goofy teddy bear adores people, has personality for days, and has one of the sweetest hearts you'll ever meet! At 2.5 years old and about 70 pounds, Jackson firmly believes he is the perfect size to be your personal shadow, weighted blanket, emotional support buddy, and full-time best friend. He takes the title 'sidekick' very seriously. Privacy? Never met her. Getting up to grab a snack? He's coming with you (and wants one too) Going to run errands? He's by his leash ready to go! Need to use the bathroom? Well... Jackson believes that's a team activity too. This all means one thing: Once Jackson bonds with you- you've got the most loyal best friend for life. 💙ENERGY AND PERSONALITY💙 Jackson is everything people love about big dogs— equal parts sweetheart and goofball! He will make you laugh with his oversized puppy antics and his determination to convince you that he is lap-dog sized. He adores meeting new people, listens well, and has a happy-go-lucky outlook on life that makes everyone fall in love with him. Jackson also loves toys, bones, car rides, naps in his humans bed, and is 100% convinced that every snack in your hand was probably meant for him. (Honestly...he makes a really compelling argument.) Jackson has a medium/balanced energy level and is happy to lounge around OR go on an adventure. He doesn't care where you're going- he's just so grateful he gets to go with you! 💙SOCIAL LIFE💙 Jackson is known to quickly wins hearts whereever he goes. He gets along very well with other dogs, though his play style is best described as "VERY enthusiastic." He'd love a larger canine friend who enjoys roughhousing as much as he does or one who doesn't mind his goofy antics. He'd also be perfectly happy soaking up all of your attention as an only dog. 💙IDEAL HOME ENVIRONMENT💙 Like many rescue dogs, Jackson is still learning that being alone isn't so scary and that his humans will always be back for him. He would do best in a home where someone is home often, or where they can make arrangements for him to spend the day with someone while they are at work (i.e: doggie daycare, hanging out with a family member/friend/sitter, etc.) After spending so much of his life without a family of his own, Jackson's hoping for a home that understands he's still healing from his rough start, will be patient as he continues to build confidence, and won't mind having a devoted sidekick who thinks life is better together. Jackson has brought so much joy to his foster home, so we know he will bring a ton of joy to your home too! At the end of the day, Jackson is just a big sweet softie that has waited far too long for a furever family that shows him endless love and safety. Jackson has spent long enough wondering when it will finally be his turn. If you're looking for a dog who will love you with his whole entire heart every single day for the rest of his life... Jackson has been waiting his whole life for you. 💙INCLUDED VETERINARY CARE💙 Jackson is up to date on vaccinations, neutered, microchipped, and receiving heartworm, flea, and tick preventatives along with routine parasite treatments and yearly routine heartworm/lyme testing.
Photo of Maggie

Maggie

Anatolian Shepherd Mixed Breed (Medium)

Female, 3 yrs 4 mos
York, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered,
Story
Location: Parkville, MD Maggie is an incredibly smart, lively girl who is always ready for her next adventure. She loves people and thrives on human companionship. While she may take a few minutes to warm up to someone new, once she does, she’s all about snuggles, pets, and plenty of sweet kisses. This girl is eager to learn, making her a great candidate for continued training. She is already crate trained, potty trained, and walks well on a leash, giving her a strong foundation for success in her forever home. She is great with other dogs after a short introduction! Maggie loves to run, play, and stay active. Whether she’s zooming around the yard, exploring on walks, or engaging her brain with training and enrichment activities, she’s happiest when she has an outlet for her energy and intelligence. On the other hand, she also loves to lay at your feet and relax while you watch a movie with the family! Maggie could excel as a working dog, farm dog, or active companion for someone looking for a partner in adventure. After a few weeks, she could even settle into a typical 9-5 routine. She loves her crate and is extremely quiet, too, making her the ideal candidate for any type of abode! If you’re looking for a smart, fun, and loving dog to share life’s adventures with, Maggie may be the perfect match!

Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in York, Pennsylvania.

Great Dane puppies and dogs in nearby cities

Related breeds in York, Pennsylvania

Great Dane shelters & rescues in York, Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in York, Pennsylvania. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Shelter

13 miles

The Pennsylvania SPCA - Lancaster

848 S Prince Street, Lancaster, PA 17603

Pet Types: cats, dogs

More an arrow icon

Rescue

22.3 miles

Adopt A Stray - PA transport

Harrisburg, PA 17105

Pet Types: dogs

More an arrow icon

Rescue

22.4 miles

Mastiffs To Mutts - Central PA

Harrisburg, PA 17109

Pet Types: dogs

More an arrow icon

Rescue

25.3 miles

Mollys Place Rescue

PO Box 328, Mechanicsburg, PA 17055

Pet Types: cats, dogs

More an arrow icon

Rescue

34.9 miles

Reach Out Rescue & Resources

P. O. Box 542, Westminster, MD 21158

Pet Types: cats, dogs

More an arrow icon

Rescue

39.5 miles

New Beginnings Animal Rescue - Carisle, PA Transport

CARISLE, PA 17013

Pet Types: cats, dogs

More an arrow icon

Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

magnifying glass with cat and dog

Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

clipboard with list

Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

Learn More an arrow icon