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Great Dane puppies and dogs in Harrisburg, Pennsylvania

Looking for a Great Dane puppy or dog in Harrisburg, Pennsylvania? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you Great Dane in cities near Harrisburg, Pennsylvania Other pups in Harrisburg, Pennsylvania Search for a Great Dane puppy or dog near you Browse Great Dane puppies and dogs in nearby cities Browse related breeds in Harrisburg, Pennsylvania Great Dane shelters and rescues in Harrisburg, Pennsylvania Learn more about adopting a Great Dane puppy or dog

Adopt a Great Dane near you in Harrisburg, Pennsylvania

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near Harrisburg, Pennsylvania

These Great Danes are available for adoption close to Harrisburg, Pennsylvania.
We'll also keep you updated on Dino's adoption status with email updates.
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Dino

Great Dane

Male, Adult
Pine Grove, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
Loves getting to know other dogs and people. Needs room to run since he gets the zoomies here and there, once he’s done he can be asleep all day. Does not bark at other dogs or people or noises but he can when told to “speak” and he knows finger guns and plays dead, he knows how to sit and lay down. Dino is bilingual in English and Spanish so if he isn’t listening in English maybe try Spanish. His big ears need to be cleaned often or they will be prone to infection and become sensitive. Dino is very sweet and has never bit anyone or anything, he’s a gentle giant.

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We'll also keep you updated on Dolly's adoption status with email updates.
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Dolly

Great Dane Labrador Retriever

Female, Adult
Westminster, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website.All of the animals posted on our site have been temperament tested. While not all are in the immediate area, once we have processed and approved your application, we will move the dog to our adoptive area for you to meet, greet and hopefully adopt. Sometimes we will have more than one application on a dog. That does not mean it automatically goes to another family but you should be aware of the fact that until you are approved and set up for the meet/greet.. the dog could get adopted by another applicant.Dolly has large Great Dane genes grafted onto a somewhat smaller body. Not that anyone would ever call her small, but you would say she's a manageable size, which is perfect. If you love the Dane look, but aren't sure you could handle a full size model, we have Dolly waiting for you. She is currently only 60 lbs., but that is a bit deceiving, as she is very underweight. We would like to see at least 15 lbs. more on her ribs and we are working on it. She is now getting top quality groceries, something she has never had before. Still a young dog, at only about 2 years old, she is in the process of learning about how to deal with the world around her and she is learning fast. Her foster has some comments to help you understand this 'dog-in-progress. 'She’s nervous around new people and things. She does warm up after a bit. Her initial reaction to people that she doesn’t know is to low growl. She is trying to tell everyone to give her a moment to process the new information. I don’t recommend a house with cats or small animals. She’ tries to chase down all the birds,  and squirrels when we’re outside. I’m fairly confident her life prior to rescue wasn’t a good one. It's heartbreaking seeing a good dog trying to cope with a world she was never shown. UPDATE:I have had her for a month now, and she is learning! I took her to the vet today, and while she was nervous, she did not growl. So there has been improvement on that aspect. She wasn’t super outgoing and wanting everyone’s attention, so definitely stand by the slower to warm up to strangers. I highly suspect she’s been abused. She is highly intelligent and learns new things really fast.  She really has the potential to be an excellent dog, and wants to be loved and please her person. MORE UPDATE: Since being here at my house over a month now I have some new insights into her. She is not dog friendly with all dogs.  She's OK with my male dog, but not so happy with my female.  I've been working on getting her to ignore people on walks and she's doing better. She doesn't like it if strangers get to close when we are out.  In the yard. she's definitely going to need at least a 6 foot fence to keep her safely secured.  I will say, she is house trained and does let you know when she needs to go out. She also does very well in her kennel. She is very smart, and can learn things pretty quickly. She has all her shots and is ready and waiting for the person or family who like bigger dogs, but aren't ready for an actual Goliath. Dolly is a good girl! She is hoping you will want to help her be a good dog and come for her soon.   If you are interested in Dolly, please fill out an application at: https://reachoutrescue.rescuegroups.org/forms/form?formid=4588    Or contact: rorrcanine@gmail.com   *** Click here to sponsor this dog! ***Visit this organization's web site to see any additional information available about this pet.April 17, 2026, 4:04 pm

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We'll also keep you updated on Harriet's adoption status with email updates.
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Harriet

Great Dane

Female, 1 mo
Sinking Spring, PA
Size
(when grown) -
Details
Good with dogs, Good with cats,
Story
💕Meet Harriet!!!💕 This irresistibly adorable Great Dane puppy is on the hunt for her forever home. Harriet was born in our care after her Mama (Harley) was surrendered by a commercial breeder. Harriet is the sweetest puppy you will meet. At 6 weeks old and almost 16 lbs., she is going to be anything but little. Harriet is a typical puppy… sleeping, eating, playing, pooping and repeat. She is very sweet and loving but also already in the ankle biting stage with her little shark teeth🦈. She is super curious about her surroundings and enjoys exploring. She loves to steal slippers and pretty much anything else she can get her little chompers on. She has been doing well with redirection to an appropriate item to carry around and chew on. She enjoys playing with toys of all sorts of textures. She gets along great with the other dogs in her foster home, both bigger and smaller than her. She enjoys tumbling around with the other dogs or just curling up with them for a nap. Harriet also loves to be held and will snuggle into you before falling asleep for a little nap. 😴 She has been around cats and has shown no interest in them currently. She has only been around older teenaged children. She is currently being kept in an open xpen at night or when her foster mom is not home. She does vocalize that she is not happy about being in her pen in a room away from all the action but does settle down after a little while. She is being spoiled with the “alexa” always playing something for her, from white noise and classical music to todays top hits. And a little treat always helps to make things a little better when its quite time. Which Harriet is VERY food motivated. She is a little piggy when it is time to eat, she would try to steal her mama’s dry kibble. Harriet is currently on a mixture of wet food and large breed puppy kibble and loving every bite. Harriet is already microchipped and has her first round of age-appropriate vaccinations. Based on when she is adopted will determine if she will receive another round of vaccinations while still in foster care or if her forever home will need to finish her vaccines that will be spread out over the coming months. Harriet is way to young to be fixed and will be adopted out on a spay contract. The spay contract comes with an additional fee on top of the adoption fee and states that at the age of one year old Harriet will need to be spayed and have gastropexy surgery, this is nonnegotiable. The additional fee will be refunded once the surgeries are completed per the contract. Harriet’s ideal forever home will have large breed experiences and the understanding of what it costs to keep and properly care for a dog of this breed and size. No apartments for this sweet girl, she will need a home with plenty of room for her to spread out. A fence is not required but always appreciated. And the same goes for another dog, it’s always nice to have a playmate but not a deal breaker. 🐾If you think this adorable “little” girl would make the perfect addition to your family apply today!!!!🐾 🚨🚨🚨🚨🚨Harriet will not be adopted out until she is at least 8 weeks old. We are opening applications at this time in hopes to have her forever family lined up for when she is old enough to go to her new home. 🚨🚨🚨🚨🚨 Meet and greets will take place in Berks County and all family members including current residential dogs will need to attend. We will only consider adopters within a 2 hour radius. www.zoeshouserescue.com Zoe’s House Kennel #9117 Sinking Spring, PA 19608

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We'll also keep you updated on Jade's adoption status with email updates.
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Jade

Great Dane

Female 6 yrs 5 mos
Sinking Spring, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
Jade is a stunning blue 6 year old Great Dane with soulful eyes, the softest heart, and the best floppy ears you’ve ever seen. On the petite side for a Dane at about 100 pounds, she’s basically the perfect “lap dog”… if your lap happens to be the size of a couch. After spending her early life being used for breeding, Jade was rescued and is now fully embracing the freedom and love she always deserved. Watching her discover the joys of being someone’s loved pet instead of a breeder has been nothing short of beautiful. Jade is the sweetest, most cuddly girl. If you love big pup snuggles, warm leaning hugs, and a constant companion who thinks personal space is overrated, she is absolutely your girl. Her ideal family won’t mind sharing the couch… or the bed… or both. Like many Great Danes, Jade can be a little nervous when meeting new people or navigating new environments. She just needs a moment to take it all in. Once she realizes she’s safe, she warms up quickly and becomes your loyal shadow. She is: *Great with other dogs *Good with kids *Likely fine with cats (though she hasn’t met one yet) *Potty trained (though some regression can happen during transitions) *Crate trained and comfortable in a gated room when left alone *A dream on leash and loves her walks Jade did have surgeries to remove benign growths on both front feet, but she has healed beautifully and is ready to move forward without looking back. Her ideal home would include a fenced yard, as she appreciates having a secure space and privacy when she does her business. More than anything, she’s looking for a calm, loving home that understands she’s had a big life before this and deserves nothing but softness from here on out. Jade is spayed and up to date on all core vaccinations and preventatives. Adopters must live within 2-3 hours of Reading, PA and be willing to travel there for a meet and greet if selected. Kennel license #9117 Reading, PA 19608

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These pups are in Harrisburg, Pennsylvania too!

Below are our newest added Great Danes available for adoption in Harrisburg, Pennsylvania. To see more adoptable Great Danes in Harrisburg, Pennsylvania, use the search tool below to enter specific criteria!
We'll also keep you updated on Peg & Bud (bonded mother & son)'s adoption status with email updates.
Photo of Peg & Bud (bonded mother & son)

Peg & Bud (bonded mother & son)

Anatolian Shepherd

Male, Adult
Harrisburg, PA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE NOTE! Unless stated otherwise, our dogs and puppies are located in Arkansas, and transported to the north/northeast once adopted. We do occasionally have dogs/puppies placed in foster homes in the north/northeast. In the cases where the pet is somewhere other than Arkansas, it will be noted beside the name of the pet.3/29/26 Meet Peg and Bud, a mother-and-son duo who have a very special bond and are looking for their forever home together! This affectionate and loyal pair will bring nothing but love and joy to your life. Peg, the gentle and smart mother, is a calm presence with a quiet nature. She is always up for a good cuddle and will be by your side through thick and thin. Bud, her playful and curious son, is full of beans and ready for any adventure. He loves to explore and is always eager to learn new things. Together, they are the perfect balance of energy and tranquility. With their loving and friendly personalities, Peg and Bud are a dream team. They are loyal to the core and will be your faithful companions. Their playful and gentle natures make them a joy to be around, and they are sure to fit right into your family. This dynamic duo is ready to find their forever home, and they can't wait to share their love and companionship with you. Could you be the one they've been waiting for? They are sure to capture your heart! Located in Arkansas and he can be adopted locally, but transport is available to the New England area as well. Adopter must be able to pick up or arrange for someone to pick up for them in PA, NY, or CT on Saturdays. To apply, please fill out the adoption app: https://form.jotform.com/212690945239059 email apps.aasr@gmail.com with any questions.Visit this organization's web site to see any additional information available about this pet.Our typical adoption fee for puppies younger than 6 months old is $400, and for older puppies and adults, the usual fee is $350. This includes microchip, spay/neuter,  up to date on age appropriate vaccinations, dewormings, flea/tick treatment, and heartworm test (if over 6 months old) as well as heartworm treatment if they test positive. There is a transport fee of $150 per dog, depending on the transporter. We use Pack Leaders Rescue Dog Transport most often, but also use Hearts Transport as well on occasion. Please visit our Facebook page too! https://www.facebook.com/adoptastrayrescueorg For more info regarding adopting, email apps.aasr@gmail.com Thank you for considering one of our rescue babies!April 15, 2026, 5:58 pm

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We'll also keep you updated on Peg & Bud (bonded mother & son)'s adoption status with email updates.
Photo of Peg & Bud (bonded mother & son)

Peg & Bud (bonded mother & son)

Anatolian Shepherd

Female, Adult
Harrisburg, PA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE NOTE! Unless stated otherwise, our dogs and puppies are located in Arkansas, and transported to the north/northeast once adopted. We do occasionally have dogs/puppies placed in foster homes in the north/northeast. In the cases where the pet is somewhere other than Arkansas, it will be noted beside the name of the pet.3/29/26 Meet Peg and Bud, a mother-and-son duo who have a very special bond and are looking for their forever home together! This affectionate and loyal pair will bring nothing but love and joy to your life. Peg, the gentle and smart mother, is a calm presence with a quiet nature. She is always up for a good cuddle and will be by your side through thick and thin. Bud, her playful and curious son, is full of beans and ready for any adventure. He loves to explore and is always eager to learn new things. Together, they are the perfect balance of energy and tranquility. With their loving and friendly personalities, Peg and Bud are a dream team. They are loyal to the core and will be your faithful companions. Their playful and gentle natures make them a joy to be around, and they are sure to fit right into your family. This dynamic duo is ready to find their forever home, and they can't wait to share their love and companionship with you. Could you be the one they've been waiting for? They are sure to capture your heart! Located in Arkansas and he can be adopted locally, but transport is available to the New England area as well. Adopter must be able to pick up or arrange for someone to pick up for them in PA, NY, or CT on Saturdays. To apply, please fill out the adoption app: https://form.jotform.com/212690945239059 email apps.aasr@gmail.com with any questions.Visit this organization's web site to see any additional information available about this pet.Our typical adoption fee for puppies younger than 6 months old is $400, and for older puppies and adults, the usual fee is $350. This includes microchip, spay/neuter,  up to date on age appropriate vaccinations, dewormings, flea/tick treatment, and heartworm test (if over 6 months old) as well as heartworm treatment if they test positive. There is a transport fee of $150 per dog, depending on the transporter. We use Pack Leaders Rescue Dog Transport most often, but also use Hearts Transport as well on occasion. Please visit our Facebook page too! https://www.facebook.com/adoptastrayrescueorg For more info regarding adopting, email apps.aasr@gmail.com Thank you for considering one of our rescue babies!April 15, 2026, 5:58 pm

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Great Dane shelters & rescues in Harrisburg, Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Harrisburg, Pennsylvania. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

44.1 miles

Reach Out Rescue & Resources

P. O. Box 542, Westminster, MD 21158

Pet Types: cats, dogs

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Rescue

45 miles

Zoe's House Rescue

P.O Box 2372, Sinking Spring, PA 19608

Pet Types: dogs

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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