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Great Dane puppies and dogs in Harrisburg, Pennsylvania

Looking for a Great Dane puppy or dog in Harrisburg, Pennsylvania? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Harrisburg, Pennsylvania

These Great Danes are available in Harrisburg, Pennsylvania.
We'll also keep you updated on Waylon's adoption status with email updates.
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Waylon

Great Dane

Male, Adult
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE NOTE! Unless stated otherwise, our dogs and puppies are located in Arkansas, and transported to the north/northeast once adopted. We do occasionally have dogs/puppies placed in foster homes in the north/northeast. In the cases where the pet is somewhere other than Arkansas, it will be noted beside the name of the pet.Arkansas or nearby! Waylon is a 2 yr old Great Dane who came into rescue after he was found as a stray. He was in horrific shape and barely survived the level of starvation he endured. But he did survive and he is thriving now! Waylon is still slowly gaining weight, and has almost reached his ideal weight. He is VERY tall. He is so sweet and loving. He want to sit in your lap and cuddle with you, as if he is a 10lb lap dog rather than 120 lb Dane. While in his foster home, he has done well with most other dogs, but it is very structured and his time with other dogs is limited. He does seem to have a jealoys streak and is possessive of his people. He does great in a doggy daycare setting and has spent lots of time in daycare, doing very well with most dogs there. I think this is a lot different than how he will behave in a home setting with other dogs sharing his humans attention. For this reason, we would love to see him adopted into a home where he can be the only dog. He is not a candidate for a home with young kids. He is just too big and clumsy, and he really wants all the attention. I feel the he may become jealous of little kids and view them as competition. We just really want to set him up for success. He's been through enough in his short life amd we want it to be easy from here on our. Waylon holds a very special place in my heart. Hes been in my home through it all- recovering from starvation, happy tail and subsequent tail amputation, heartworm treatment. The odds were stacked against him, but he made it and now he's ready to find his own home. Waylon is located in Alexander, AR. We would prefer a local adopter, within driving distance. I think that transport would be really hard on him. For more info, email apps.aasr@gmail.com or message us privately.  To apply to adopt, You can find my form 'ADOPT A STRAY RESCUE' at: https://form.jotform.com/212690945239059Visit this organization's web site to see any additional information available about this pet.Our typical adoption fee for puppies younger than 6 months old is $400, and for older puppies and adults, the usual fee is $350. This includes microchip, spay/neuter,  up to date on age appropriate vaccinations, dewormings, flea/tick treatment, and heartworm test (if over 6 months old) as well as heartworm treatment if they test positive. There is a transport fee of $150 per dog, depending on the transporter. We use Pack Leaders Rescue Dog Transport most often, but also use Hearts Transport as well on occasion. Please visit our Facebook page too! https://www.facebook.com/adoptastrayrescueorg For more info regarding adopting, email apps.aasr@gmail.com Thank you for considering one of our rescue babies!January 11, 2026, 8:24 am

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We'll also keep you updated on Big Tex's adoption status with email updates.
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Big Tex

Great Dane

Male, 3 yrs 2 mos
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Meet BIG Tex– The Handsome 180 pound 3 year old Boy from Waller, TXHe was found wandering in Waller, Texas, and while we don’t know her past, we are determined to give him the beautiful future he deserves. He is ready to find a forever home where he can feel safe, loved, and cherished.He walks well on his leash and is crate trained. He gets along well with the other dogs he is housed with. He enjoys companionship and would love a family that gives him patience, comfort, and a place to settle in.All he wants is a home where he can finally relax, feel secure, and be part of someone’s life forever. ?Located in Houston, TXTransport available to most states for a $300 fee.

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Or, how about these Great Danes in cities near Harrisburg, Pennsylvania

These Great Danes are available for adoption close to Harrisburg, Pennsylvania.
We'll also keep you updated on Waylon's adoption status with email updates.
Photo of Waylon

Waylon

Great Dane

Male, Adult
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Not good with cats, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE NOTE! Unless stated otherwise, our dogs and puppies are located in Arkansas, and transported to the north/northeast once adopted. We do occasionally have dogs/puppies placed in foster homes in the north/northeast. In the cases where the pet is somewhere other than Arkansas, it will be noted beside the name of the pet.Arkansas or nearby! Waylon is a 2 yr old Great Dane who came into rescue after he was found as a stray. He was in horrific shape and barely survived the level of starvation he endured. But he did survive and he is thriving now! Waylon is still slowly gaining weight, and has almost reached his ideal weight. He is VERY tall. He is so sweet and loving. He want to sit in your lap and cuddle with you, as if he is a 10lb lap dog rather than 120 lb Dane. While in his foster home, he has done well with most other dogs, but it is very structured and his time with other dogs is limited. He does seem to have a jealoys streak and is possessive of his people. He does great in a doggy daycare setting and has spent lots of time in daycare, doing very well with most dogs there. I think this is a lot different than how he will behave in a home setting with other dogs sharing his humans attention. For this reason, we would love to see him adopted into a home where he can be the only dog. He is not a candidate for a home with young kids. He is just too big and clumsy, and he really wants all the attention. I feel the he may become jealous of little kids and view them as competition. We just really want to set him up for success. He's been through enough in his short life amd we want it to be easy from here on our. Waylon holds a very special place in my heart. Hes been in my home through it all- recovering from starvation, happy tail and subsequent tail amputation, heartworm treatment. The odds were stacked against him, but he made it and now he's ready to find his own home. Waylon is located in Alexander, AR. We would prefer a local adopter, within driving distance. I think that transport would be really hard on him. For more info, email apps.aasr@gmail.com or message us privately.  To apply to adopt, You can find my form 'ADOPT A STRAY RESCUE' at: https://form.jotform.com/212690945239059Visit this organization's web site to see any additional information available about this pet.Our typical adoption fee for puppies younger than 6 months old is $400, and for older puppies and adults, the usual fee is $350. This includes microchip, spay/neuter,  up to date on age appropriate vaccinations, dewormings, flea/tick treatment, and heartworm test (if over 6 months old) as well as heartworm treatment if they test positive. There is a transport fee of $150 per dog, depending on the transporter. We use Pack Leaders Rescue Dog Transport most often, but also use Hearts Transport as well on occasion. Please visit our Facebook page too! https://www.facebook.com/adoptastrayrescueorg For more info regarding adopting, email apps.aasr@gmail.com Thank you for considering one of our rescue babies!January 11, 2026, 8:24 am

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We'll also keep you updated on Big Tex's adoption status with email updates.
Photo of Big Tex

Big Tex

Great Dane

Male, 3 yrs 2 mos
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Meet BIG Tex– The Handsome 180 pound 3 year old Boy from Waller, TXHe was found wandering in Waller, Texas, and while we don’t know her past, we are determined to give him the beautiful future he deserves. He is ready to find a forever home where he can feel safe, loved, and cherished.He walks well on his leash and is crate trained. He gets along well with the other dogs he is housed with. He enjoys companionship and would love a family that gives him patience, comfort, and a place to settle in.All he wants is a home where he can finally relax, feel secure, and be part of someone’s life forever. ?Located in Houston, TXTransport available to most states for a $300 fee.

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We'll also keep you updated on Black Beauty's adoption status with email updates.
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Black Beauty

Great Dane

Male, 2 yrs 2 mos
York, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Current Location: Parsonsburg, MD Meet Black Beauty: A Stunning Great Dane Ready for the Right Match At 95 pounds and 2 years old, this stunning Great Dane is exactly what his name promises: absolutely beautiful. With his sleek black coat and commanding presence, Black Beauty is a head turner who embodies everything magnificent about this gentle giant breed. Black Beauty has a rambunctious play style that's full of energy and enthusiasm. He needs other dogs who are able to read his cues and interact well with his spirited approach to play. The good news? He's lived successfully with several other dogs, kids, and even cats, showing that with the right companions and environment, he can thrive in a multi pet household. This active boy would be best in an environment where he has space to run and play. He needs regular exercise to burn off his energy and keep him happy and balanced. Black Beauty also loves puzzles and things that use his brain power, showing that he's not just physically active but mentally engaged as well. A Great Dane who can think and problem solve is a wonderful companion for someone who enjoys interactive training and enrichment activities. Due to his size and exuberance, Black Beauty would likely do best in a home without small children. His enthusiasm and large frame could be overwhelming for little ones, even though his intentions are purely loving. Black Beauty is waiting for someone who knows and loves the Great Dane breed, someone who understands their unique needs and incredible hearts. He needs a companion and guide who can provide him with structure, exercise, mental stimulation, and the love he deserves. If you're experienced with large breeds and ready for a stunning, intelligent boy who will fill your life with loyalty and companionship, Black Beauty is ready to meet you.

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We'll also keep you updated on Skye's adoption status with email updates.
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Skye

Great Dane Mixed Breed (Large)

Female, 3 yrs 1 mo
York, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
Current Location: Rockville, MD Hello! My name is Skye! I'm coming to OPH on 1/9/2026. Please check back soon for updates on my personality, and to see adorable new photos. I’m looking for my forever family! Is that with you? If so please click “apply for adoption” or submit an application through the Adopt tab. Let’s get our family started!

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We'll also keep you updated on Toothless's adoption status with email updates.
Photo of Toothless

Toothless

Great Dane

Male, 3 yrs 9 mos
York, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Found in York Haven On Walton St.

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We'll also keep you updated on Dolly's adoption status with email updates.
Photo of Dolly

Dolly

Great Dane Labrador Retriever

Female, Adult
Westminster, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website.All of the animals posted on our site have been temperament tested. While not all are in the immediate area, once we have processed and approved your application, we will move the dog to our adoptive area for you to meet, greet and hopefully adopt. Sometimes we will have more than one application on a dog. That does not mean it automatically goes to another family but you should be aware of the fact that until you are approved and set up for the meet/greet.. the dog could get adopted by another applicant.Dolly has large Great Dane genes grafted onto a somewhat smaller body. Not that anyone would ever call her small, but you would say she's a manageable size, which is perfect. If you love the Dane look, but aren't sure you could handle a full size model, we have Dolly waiting for you. She is currently only 60 lbs., but that is a bit deceiving, as she is very underweight. We would like to see at least 15 lbs. more on her ribs and we are working on it. She is now getting top quality groceries, something she has never had before. Still a young dog, at only about 2 years old, she is in the process of learning about how to deal with the world around her and she is learning fast. Her foster has some comments to help you understand this 'dog-in-progress. 'She’s nervous around new people and things. She does warm up after a bit. Her initial reaction to people that she doesn’t know is to low growl. She is trying to tell everyone to give her a moment to process the new information. I don’t recommend a house with cats or small animals. She’ tries to chase down all the birds,  and squirrels when we’re outside. I’m fairly confident her life prior to rescue wasn’t a good one. It's heartbreaking seeing a good dog trying to cope with a world she was never shown. UPDATE:I have had her for a month now, and she is learning! I took her to the vet today, and while she was nervous, she did not growl. So there has been improvement on that aspect. She wasn’t super outgoing and wanting everyone’s attention, so definitely stand by the slower to warm up to strangers. I highly suspect she’s been abused. She is highly intelligent and learns new things really fast.  She really has the potential to be an excellent dog, and wants to be loved and please her person. MORE UPDATE: Since being here at my house over a month now I have some new insights into her. She is not dog friendly with all dogs.  She's OK with my male dog, but not so happy with my female.  I've been working on getting her to ignore people on walks and she's doing better. She doesn't like it if strangers get to close when we are out.  In the yard. she's definitely going to need at least a 6 foot fence to keep her safely secured.  I will say, she is house trained and does let you know when she needs to go out. She also does very well in her kennel. She is very smart, and can learn things pretty quickly. She has all her shots and is ready and waiting for the person or family who like bigger dogs, but aren't ready for an actual Goliath. Dolly is a good girl! She is hoping you will want to help her be a good dog and come for her soon.   If you are interested in Dolly, please fill out an application at: https://reachoutrescue.rescuegroups.org/forms/form?formid=4588    Or contact: rorrcanine@gmail.com   *** Click here to sponsor this dog! ***Visit this organization's web site to see any additional information available about this pet.December 26, 2025, 11:42 am

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These pups are in Harrisburg, Pennsylvania too!

Below are our newest added Great Danes available for adoption in Harrisburg, Pennsylvania. To see more adoptable Great Danes in Harrisburg, Pennsylvania, use the search tool below to enter specific criteria!
We'll also keep you updated on Sheila's adoption status with email updates.
Photo of Sheila

Sheila

Anatolian Shepherd

Female, Adult
Harrisburg, PA
Size
(when grown) -
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website.Hey all, I'm Sheila, a 60# gal 3 years old thought to be an Anatolian Shepherd mix of something!  Left at my disabled 'Grandma's House' by owners, Grandma had no way to care for me correctly. After a few months of trying, she turned me into a shelter in WV. Unfortunately Grandma didn't know it was a High Kill Shelter. YIKES! Double YIKES!! Fortunately, word went out far and wide, SAVE SHEILA, SAVE SHEILA! Cries were heard and I'm now in a loving foster home in Dillsburg. Got other doggie friends here to show me the ropes and I'm doing fine per foster mom/dad.  I did get my Christmas wish and was adopted, but sadly, I was returned ON CHRISTMAS! Not the gift I was looking for. The family, though nice, didn't know their abilities to walk a gal with energy. Yes, I admit I need walking skills yet, but foster mom, though old and gray, is able to walk me NO ISSUES. Guess we all are different. So, here's my story, Sad to be returned but that perfect family is out there!  Good with other dogs, people, children (not toddlers) I do admit my 'Zest for Life' does get the better of me with excitement with life it's self! Smart as a whip already knowing sit, down, give both paws, am crate trained & house trained, I do have a little stubborn streak thrown in for good measures! Now learning Patients, Sit and Wait at door and to eat. I do pull on a leash, but can learn or use of a Halti would stop that no problem.  NO Way am I going to be protective. So far I've shown only friendliness, kiss giving and a 'Lets Party Attitude' to new people.  My recall has improved but a Physical Fence/Underground Fence would be best for me. I am VERY FOOD MOTIVATED!  Life is short let's Start the New Year with a BANG Together!  Interested in meeting me?  Complete an on-line application at www.CastawayCritters.org/adopt. Pa Kennel License: 04736Visit this organization's web site to see any additional information available about this pet.January 15, 2026, 8:56 pm

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Harrisburg, Pennsylvania.

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Great Dane shelters & rescues in Harrisburg, Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Harrisburg, Pennsylvania. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

5 miles

Adopt A Stray - PA transport

Harrisburg, PA 17105

Pet Types: dogs

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Shelter

6.7 miles

Waiting Under the Willow Foundation - PA Transport

Harrisburg, PA 17112

Pet Types: dogs

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Rescue

22.3 miles

Operation Paws for Homes

York, PA 17401

Pet Types: cats, dogs

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Shelter

22.5 miles

York County SPCA

3159 Susquehanna Trail North, York, PA 17406

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

44.1 miles

Reach Out Rescue & Resources

P. O. Box 542, Westminster, MD 21158

Pet Types: cats, dogs

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Rescue

45 miles

Zoe's House Rescue

P.O Box 2372, Sinking Spring, PA 19608

Pet Types: dogs

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Rescue

45.7 miles

Haven to Home Canine Rescue

Winfield, PA 17889

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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