Great Dane Adoption in Pennsylvania: Great Dane Puppies for Sale in Pennsylvania

Adopt a Great Dane near you in Pennsylvania

Below are our newest added Great Danes available for adoption in Pennsylvania. To see more adoptable Great Danes in Pennsylvania, use the search tool below to enter specific criteria!

Minnie

Great Dane/Mixed Breed (Medium)

Female, 1 yr 2 mos

Birdsboro, PA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, Good with cats,

Story

Minnie is a gentle, resilient mama who has blossomed beautifully in foster care. When she first arrived, she was understandably nervous and protective while caring for her puppies—but as they’ve grown, Minnie has gained so much confidence and is truly coming into her own. Minnie is a gentle, loving girl who has truly come out of her shell in foster care. She may be a little shy in new situations, but she is eager to try and gains confidence with reassurance. Once she bonds with her person, she is incredibly affectionate and loves to snuggle. In foster, Minnie did wonderfully with other dogs and enjoyed playful, supportive friendships. She also lived peacefully with cats and wasn’t bothered by them at all. Minnie would thrive in a patient, loving home that will continue to help her build confidence and enjoy all the good things life has to offer. Available at the Animal Rescue League of Berks County, Birdsboro Pa 19508, KL#1257

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Penelope

Great Dane

Female, 2 yrs 1 mo

Malvern, PA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

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Cole (courtesy post)

Great Dane

Male, Senior

Pittsburgh, PA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, House-trained,

Story

Have you ever met a dog that is just steals your heart the very moment you see them for the first time? Charming COLE is one such dog. He’s a handsome boy who is an owner release to our shelter, and while very sad to be living with us after having a home, he is enjoying being the apple of the shelter staff's eyes. This dapper gentleman has a sweet frosted face, the only sign of his older age. This Great Dane /mix is still treat motivated, meaning you can easily win him over with treats, but he also adores the adoration of his fans (there are many of us! ) – he lives for love and attention. Your smiles and cuddles and making a fuss over him will work almost as well as those tasty tidbits. If you’re looking for the perfect cuddly senior companion to keep you warm this winter, look no further than COLE. He is a golden boy with a golden heart! Cole is a courtesy post for the Brooke County Animal Shelter in Beechbottom, WV, about 45 minutes from Pittsburgh. Please contact the shelter at 304-394-0800 for more information about Cole or to arrange a meet and greet. January 19, 2026, 12:35 pm

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Bocephus

Great Dane/Labrador Retriever

Male, Young

Glen Rock, PA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Not good with dogs, Not good with cats, House-trained,

Story

Bocephus is 3.5 years old. We have had him since he was a puppy. We have two other dogs. He started having knee issues a year and a half ago. We have had both knees repaired/replaced. Since his knee issues he would randomly fight one of my other dogs. This continued after the second surgery. He got into a fight on Sunday again and we just cannot keep him with the other two. He has never shown aggression to humans or even our chickens.He has never bit or nipped anyone. He is a great dog, but just needs a home with no other pets.

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Sutton (Sweet Six) 011026

Great Dane/Goldendoodle

Female, 3 mos

Kimberton, PA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats,

Story

Meet Sutton! Breed: Great Dane/Goldendoodle Mix Estimated DOB: 09/26/2025 Sex: Female (intact) Weight: 30-35 lbs Currently up to date on all age appropriate vaccinations Things To Know about Sutton: Rescued as part of an unwanted litter in Mississippi Loves people of all ages and sizes and is very affectionate Has interacted wonderfully with teens, adults, and other dogs Super playful and silly personality that brings laughter daily Loves to follow you around everywhere Typical puppy energy level that is balanced with good nap times Playful and loves toys, especially starting to enjoy playing ball Very food motivated which makes training easier Does well with leash training and is gaining confidence with new sights and sounds Crate training is improving daily - goes in willingly with a treat, sleeps through the night from 10-6:30, and keeps her crate clean Housebreaking is going well and she's starting to go to the door when she needs out Dog friendly and loves to play Young enough to learn to love cats Looking for a loving and committed forever home to provide her with the care and love she deserves Learn more and apply to adopt at TLCrescuePA.org/adopt Interested in fostering? Join our 100% foster-based team at tlcrescuepa.org/foster. #AdoptSutton #SweetSix #TLCRescuePA ##2621656##

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Steele (Sweet Six) 011026

Great Dane/Goldendoodle

Female, 3 mos

Kimberton, PA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats,

Story

Meet Steele! Breed: Great Dane/Goldendoodle Mix Estimated DOB: 09/26/2025 Sex: Female (intact) Weight: 30-35 lbs Currently up to date on all age appropriate vaccinations Things To Know about Steele: Rescued as part of an unwanted litter in Mississippi Loves people of all ages and sizes and thrives on attention Great with kids and has done well meeting other dogs Outgoing personality and natural leader Gentle, silly, and playful with a lovable nature Loves outdoor adventures followed by cozy nap times Working on leash training Settles quickly in her crate and sleeps through the night Doing well with housetraining with only occasional accidents Dog friendly Young enough to learn to love cats Looking for a loving and committed forever home to provide her with the care and love she deserves Learn more and apply to adopt at TLCrescuePA.org/adopt Interested in fostering? Join our 100% foster-based team at tlcrescuepa.org/foster. #AdoptSteele #SweetSix #TLCRescuePA ##2621660##

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Great Dane puppies and dogs in Pennsylvania

Jump to:

Adopt a Great Dane near you in Pennsylvania

Below are our newest added Great Danes available for adoption in Pennsylvania. To see more adoptable Great Danes in Pennsylvania, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in Pennsylvania cities

Great Dane shelters & rescues in Pennsylvania

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics