Great Dane Adoption in Pennsylvania: Great Dane Puppies for Sale in Pennsylvania

Adopt a Great Dane near you in Pennsylvania

Below are our newest added Great Danes available for adoption in Pennsylvania. To see more adoptable Great Danes in Pennsylvania, use the search tool below to enter specific criteria!

Bruce

Great Dane/American Pit Bull Terrier

Male, Adult

Marietta, PA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, House-trained,

Story

Can’t be off leash or he will run away. If you have a fenced in yard he will run around it all day

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Caroline

Great Dane

Female, Adult

Philadelphia, PA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Meet Caroline!She is a gentle giant with a heart made of gold. She loves treats, manicures, and giving hugs. She is a professional greeter, running to give lovins to her family every time they come home. She lives for playtime, but loves a good cuddle buddy. She would be a wonderful addition to anyone`s life.---If you are interested in adopting, please email adoptions@pspca.org._______________The Pennsylvania SPCA350 E Erie Ave., Philadelphia, PA 19134Kennel #3079

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Rhoads

Great Dane/American Pit Bull Terrier

Male, 3 mos

Malvern, PA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Hello, my name is: RhoadsApprox. DOB: 03/15/2026Weight: ~30 lbsSex/Breed: Male great dane/pittie mixRescued From: Found strayMeet Bailey, Mills, and Rhoads!These three pups were found together after being abandoned on the side of the road. Can you imagine how someone could dump living beings like that? Thankfully, they were safely captured. Their patient foster family went straight to work building their confidence and they’ve come around nicely. They love treats, are making great progress with training, and enjoy both playtime and relaxing. They would do best with another confident dog to lead the way or someone home a lot to help them continue to thrive. Based Bailey, Mills, and Rhoads are going to be BIG dogs when the grow up… that just means there will be more to love! If you`re looking for a loyal best friend, one of these pups may be the perfect fit!All our pets are microchipped, spayed/neutered, and up to date on vaccinations and preventatives.Interested in adopting? Take the first step and complete an adoption application: www.all4pawsrescue.com/adoptionWant to help? Get involved! www.all4pawsrescue.com/get-involvedAll 4 Paws is a non-profit, all-breed, no-kill animal rescue based in Malvern, PA. As a foster-based organization, we do not have a kennel facility you can visit. All adoptions must take place at our office in Malvern, PA so adopters living outside of our area should be prepared to travel. Please read our FAQs to learn more about us: www.all4pawsrescue.com/faq All 4 Paws Rescue, P.O. Box 122, Chester Springs PA 19425. PA Kennel License #11772.

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Bailey

Great Dane/American Pit Bull Terrier

Female, 3 mos

Malvern, PA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Hello, my name is: BaileyApprox. DOB: 03/15/2026Weight: ~30 lbsSex/Breed: Female great dane/pittie mixRescued From: Found strayMeet Bailey, Mills, and Rhoads!These three pups were found together after being abandoned on the side of the road. Can you imagine how someone could dump living beings like that? Thankfully, they were safely captured. Their patient foster family went straight to work building their confidence and they’ve come around nicely. They love treats, are making great progress with training, and enjoy both playtime and relaxing. They would do best with another confident dog to lead the way or someone home a lot to help them continue to thrive. Based Bailey, Mills, and Rhoads are going to be BIG dogs when the grow up… that just means there will be more to love! If you`re looking for a loyal best friend, one of these pups may be the perfect fit!All our pets are microchipped, spayed/neutered, and up to date on vaccinations and preventatives.Interested in adopting? Take the first step and complete an adoption application: www.all4pawsrescue.com/adoptionWant to help? Get involved! www.all4pawsrescue.com/get-involvedAll 4 Paws is a non-profit, all-breed, no-kill animal rescue based in Malvern, PA. As a foster-based organization, we do not have a kennel facility you can visit. All adoptions must take place at our office in Malvern, PA so adopters living outside of our area should be prepared to travel. Please read our FAQs to learn more about us: www.all4pawsrescue.com/faq All 4 Paws Rescue, P.O. Box 122, Chester Springs PA 19425. PA Kennel License #11772.

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Mills

Great Dane/American Pit Bull Terrier

Male, 3 mos

Malvern, PA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Hello, my name is: MillsApprox. DOB: 03/15/2026Weight: ~30 lbsSex/Breed: Male great dane/pittie mixRescued From: Found strayMeet Bailey, Mills, and Rhoads!These three pups were found together after being abandoned on the side of the road. Can you imagine how someone could dump living beings like that? Thankfully, they were safely captured. Their patient foster family went straight to work building their confidence and they’ve come around nicely. They love treats, are making great progress with training, and enjoy both playtime and relaxing. They would do best with another confident dog to lead the way or someone home a lot to help them continue to thrive. Based Bailey, Mills, and Rhoads are going to be BIG dogs when the grow up… that just means there will be more to love! If you`re looking for a loyal best friend, one of these pups may be the perfect fit!All our pets are microchipped, spayed/neutered, and up to date on vaccinations and preventatives.Interested in adopting? Take the first step and complete an adoption application: www.all4pawsrescue.com/adoptionWant to help? Get involved! www.all4pawsrescue.com/get-involvedAll 4 Paws is a non-profit, all-breed, no-kill animal rescue based in Malvern, PA. As a foster-based organization, we do not have a kennel facility you can visit. All adoptions must take place at our office in Malvern, PA so adopters living outside of our area should be prepared to travel. Please read our FAQs to learn more about us: www.all4pawsrescue.com/faq All 4 Paws Rescue, P.O. Box 122, Chester Springs PA 19425. PA Kennel License #11772.

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Special Needs

Picasso

Great Dane

Male, Young

Pottstown, PA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Not good with dogs, Needs special attention, House-trained,

Story

Picasso is a very sweet very big baby. He loves to be loved and loves pets. He has to sleep with someone because he gets scared at night. He is 100% deaf so he needs to feel the comfort of someone there with him. He is a huge goofball, he snores really loud, he gallops around the house, he loves to play ball and tear the squeakers out of every single toy he has. He loves ice cubes and the caps off of water bottles. He is absolutely obsessed with water. Like most Danes, he has no clue how to drink water without sticking his whole face in it and then leaving a trail of water from one room to the next. He is only 1 and a half and has plenty of silly puppy energy. He doesn’t seem to get along well with other male dogs. He’s never been around cats so I don’t know how he would react. He’s ok around the bunnies we have and hasn’t chased anything in the yard. He’s afraid of turtles that wander in the yard. He’s very lovable and really thinks he’s a 130lb lap dog.

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Pennsylvania.

Great Dane puppies and dogs in Pennsylvania

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Below are our newest added Great Danes available for adoption in Pennsylvania. To see more adoptable Great Danes in Pennsylvania, use the search tool below to enter specific criteria!

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Great Dane puppies and dogs in Pennsylvania

Jump to:

Adopt a Great Dane near you in Pennsylvania

Below are our newest added Great Danes available for adoption in Pennsylvania. To see more adoptable Great Danes in Pennsylvania, use the search tool below to enter specific criteria!

Search for a Great Dane puppy or dog

Great Dane puppies and dogs in Pennsylvania cities

Great Dane shelters & rescues in Pennsylvania

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Dane puppy or dog ?

Great Dane information

Great Dane basics