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Mastiff puppies and dogs in El Cajon, California

Looking for a Mastiff puppy or dog in El Cajon, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near El Cajon, California Other pups in El Cajon, California Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in El Cajon, California Mastiff shelters and rescues in El Cajon, California Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in El Cajon, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near El Cajon, California

These Mastiffs are available for adoption close to El Cajon, California.
We'll also keep you updated on PJ's adoption status with email updates.
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PJ

Mastiff

Male, Young
San Diego, CA
Size
(when grown) -
Details
Not good with kids, Not good with dogs, Not good with cats, Spayed or Neutered,
Story
How this pet arrived:PJ was brought in by a Humane Law Officer. Why this pet is the one for you:Meet PJ, a sweet and playful pup looking for a loving and patient new home! PJ may be a bit shy at first, but don't let that fool you - this gentle giant has a heart of gold just waiting to shine. He appreciates slow introductions and will reward your kindness with sweet, tender affection. Once he feels comfortable, he will solicit pets and stretch out on his side to lounge in the sun. PJ will thrive with adopters who allow him to adjust at his pace and can continue his positive reinforcement training. He loves treats, making training sessions a breeze! If you're ready to give PJ the love and patience he deserves, and help this shy boy blossom, come speak to an adoption counselor today! At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for adoption! Primary Color: Brindle Weight: 109 Age: 1yrs 9mths 3wks

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We'll also keep you updated on Ponyboy's adoption status with email updates.
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Ponyboy

Mastiff

Male, Adult
San Diego, CA
Size
(when grown) -
Details
Not good with kids, Not good with dogs, Not good with cats, Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by a community member. Why this pet is the one for you:Meet Ponyboy, a sweet and lovable dog with a heart as big as his size! This gentle giant is the definition of a laid-back companion who thrives on love and affection. Despite his imposing stature, Ponyboy is as soft-hearted as they come. He loves nothing more than lounging around, basking in attention, and enjoying the occasional treat-he's definitely a treat connoisseur! Ponyboy has a calm and patient demeanor, making him an excellent companion for families or individuals looking for a relaxed, easygoing pet. He's incredibly sweet and affectionate, forming strong bonds with those who show him kindness. Whether it's a leisurely walk or a snuggle session on the couch, Ponyboy is content to just be by your side, showing his devotion with his big, soulful eyes. If you're looking for a laid-back, loving giant to share your home with, Ponyboy is your guy! His love for treats and gentle nature will bring endless joy to your life. Come meet this lovable boy-he's ready to find his new home, and he can't wait to shower you with all the love you can handle. At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for their new home! Primary Color: Black Weight: 139 Age: 6yrs 0mths 3wks

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We'll also keep you updated on Vampira's adoption status with email updates.
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Vampira

Mastiff

Female, Adult
San Diego, CA
Size
(when grown) -
Details
Not good with kids, Not good with dogs, Not good with cats, Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by our Humane Law Enforcement team. Why this pet is the one for you:Meet Vampira, a gentle soul residing in our shelter. Despite her unique name, she's nothing but kindness personified. With a shy and reserved demeanor, she might take a little while to warm up to new people. But once she does, her gentle nature shines through. She's unsure if she's house trained, but with patience and love, she's ready to learn. She can be a bit nervous, but her sweet temperament is sure to win you over. She's the perfect companion for someone who understands that trust takes time to build. Adopt Vampira, because every dog deserves a loving home where they can thrive! At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for their new home! Primary Color: Tan Weight: 83 Age: 5yrs 0mths 3wks

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We'll also keep you updated on Jughead's adoption status with email updates.
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Jughead

Mastiff American Staffordshire Terrier

Male, 2 yrs 1 mo
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Not good with dogs, Not good with cats, Spayed or Neutered,
Story
Meet Linden! DOB: March 2023Weight: 70lbsDisposition: Friendly, Engaged, HappyHistory: Rescued from a shelter in LA County by TBL in March 2025Best Home: Amazing Qualities: If you're interested in meeting this dog, please visit our website to fill out an adoption application: www.thebarkinglot.net/adoptOur dogs are located in San Diego County, CA. We will happily consider out of town applications and can conduct virtual play dates with interested adopters. We have monthly transport to various locations in the Pacific Northwest, individual arrangements would need to be made for other locations across the US and Canada.To initiate the adoption process for this dog, please complete our online application by clicking below. Your adoption coordinator will respod to you via email once they receive your application: www.thebarkinglot.net/adopt

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We'll also keep you updated on Hannah's adoption status with email updates.
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Hannah

Mastiff American Pit Bull Terrier

Female, Adult
Riverside, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
COURTESY POST Hannah’s journey hasn’t been an easy one. She found herself scared and just days away from giving birth at one of California’s toughest high-kill shelters, where she and her 10 puppies were placed on the euthanasia list. But Real Good Rescue and two amazing rescue partners came together to save this brave mama. Despite losing seven of her puppies during this tough transition, Hannah’s spirit never wavered. She proved to be the most loving and dedicated mother, nurturing her babies with unwavering attention, care and play. Thanks to her, all three surviving puppies were quickly adopted into loving homes. And like most mama dogs, Hannah was overlooked. Now, it’s Hannah’s turn to find the forever home she so deeply deserves. At 75lbs and approximately 4 years old, Hannah is the perfect mix of active and chill. She’s a social butterfly who’s lived harmoniously with small dogs and even a 5-year-old child. However, her dream home would be calm, peaceful, and all about her—no other pets, just allowing Hannah to soak up all the love. Outdoors, she enjoys staying active and exploring, but indoors she’s the ultimate couch potato, ready for cuddles and naps. If you or someone you know is ready to give this incredible girl the life and love she’s been waiting for, email adopt@realgood.dog

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We'll also keep you updated on Spartan's adoption status with email updates.
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Spartan

Mastiff American Pit Bull Terrier

Male, Adult
Oceanside, CA
Size
(when grown) -
Details
Not good with kids, Not good with dogs, Not good with cats, Spayed or Neutered,
Story
How this pet arrived: Spartan was brought in by Humane Law Enforcement on March 16, 2025. Why this pet is the one for you:Spartan is a cute boy with a big blocky head and an even bigger personality! This handsome guy loves his toys and can happily entertain himself. He's a strong boy who could use some refreshers on leash manners-he sometimes forgets how big he is! Spartan can get a little overexcited and has some barrier reactivity, so he'd benefit from positive reinforcement training to help him be his best self. He has some skin issues that may be allergy-related, so his new family should be prepared to help him manage that. Due to his size and energy, he's looking for a home with kids over 10. If you're ready for a fun-loving, toy-obsessed best friend, Spartan is waiting to meet you! At SDHS:Spartan has been vaccinated, microchipped and spayed/neutered. Spartan is now ready for his new home! Primary Color: White Secondary Color: Brown Weight: 81.6 Age: 3yrs 4mths 0wks

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Mastiff puppies and dogs in nearby cities

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Related breeds in El Cajon, California

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Mastiff shelters & rescues in El Cajon, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in El Cajon, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

17 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

18.1 miles

The Barking Lot

San Diego, CA 92117

Pet Types: dogs

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Shelter

38.7 miles

San Diego Humane Society - Oceanside Campus (Dogs)

2905 San Luis Rey Road, Oceanside, CA 92058

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

38.7 miles

Underdog Heroes

Riverside, CA 92058

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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