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Mastiff puppies and dogs in El Cajon, California

Looking for a Mastiff puppy or dog in El Cajon, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near El Cajon, California Other pups in El Cajon, California Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in El Cajon, California Mastiff shelters and rescues in El Cajon, California Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in El Cajon, California

These Mastiffs are available in El Cajon, California.
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Smalls

Mastiff

Male, Young
El Cajon, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by their previous owner on August 29, 2026. Why this pet is the one for you: Say hello to Smalls! Smalls is a lovable boy with plenty of personality and a charm that is all his own. He is ready to trade shelter life for a home where he can settle in, learn the routine, and share everyday moments with his new people. Smalls is looking for a family excited to welcome a one-of-a-kind companion into their lives. If you’d like to meet this sweet pup, speak with our team today! At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for adoption! Primary Color: Blue Weight: 100 Age: 1yrs 1mths 1wks

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Rigsby

American Pit Bull Terrier Mastiff

Male, Adult
El Cajon, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by a community member on August 18, 2026. Why this pet is the one for you: Say hello to Rigsby! Rigsby is a sweet dog who can be a little shy when meeting new people, but he warms up quickly once he gets comfortable. With a little patience and a gentle approach, he is happy to show off his affectionate side! Rigsby would love to meet someone who can give him the time he needs to feel at ease. At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for adoption! Primary Color: Brindle Weight: 67 Age: 5yrs 0mths 2wks

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Or, how about these Mastiffs in cities near El Cajon, California

These Mastiffs are available for adoption close to El Cajon, California.
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Photo of Smalls

Smalls

Mastiff

Male, Young
El Cajon, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by their previous owner on August 29, 2026. Why this pet is the one for you: Say hello to Smalls! Smalls is a lovable boy with plenty of personality and a charm that is all his own. He is ready to trade shelter life for a home where he can settle in, learn the routine, and share everyday moments with his new people. Smalls is looking for a family excited to welcome a one-of-a-kind companion into their lives. If you’d like to meet this sweet pup, speak with our team today! At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for adoption! Primary Color: Blue Weight: 100 Age: 1yrs 1mths 1wks

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NALA

Mastiff

Female, 4 yrs
Chula Vista, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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GRANDE

Mastiff

Male, 2 yrs 1 mo
Chula Vista, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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Photo of Katia

Katia

Mastiff

Female
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by a community member Why this pet is the one for you:Meet Katia, a sweet and gentle pup looking for a loving new home! Katia can be a bit shy with new faces and spaces and appreciates some extra time to build trust. Once she feels comfortable, she blossoms into a outgoing, bubbly companion. Katia is a patient, sweet ball of kindness. Because of Katia's shy nature, she may thrive best in a lower-traffic household without too much loud noise. Going slow at first with introducing new people will help make Katia feel at ease. If you're ready to give Katia the love and care she deserves, speak to an adoption counselor to learn more today! At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for adoption!Shy/Fearful Dog: This pet requires a virtual behavior consult, please watch THIS video to learn more about them. Primary Color: Blue Weight: 72

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Special Needs
Photo of Howie

Howie

Mastiff

Male, Adult
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Needs special attention, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Howie is a lovely 4-year old Mastiff with a large heart and lots of love to give! He's very playful (with his favorite being tug of war), loves to run around, go on leisurely walks, and most of all relax at home with his family. If you're looking for a cuddle buddy, your search has ended as Howie loves to cuddle up whether it be next to his person or even just at their feet. His love isn't limited to people only as Howie also gets along with other pets at home. Howie thrives in homes where he's kept company with someone else or another furry companion. After having the pleasure of being Howie's family, we've experimented with many food brands and have found the ScienceHill prescribed Gastrointestinal Biome Dog Food works best for his stomach. Furthermore, Howie is prone to anxiety and is currently on Fluoxetine.

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Photo of Scarlett

Scarlett

Mastiff Great Dane

Female, Young
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
This is Scarlett.She is an "American Molossus", but the form doesn't have that as an option. Her mom is full American Molossus, her dad is half American Molossus, half Great Dane. So she's a little more slender than her breed usually gets, but she's still a big girl (220+ lbs).All my life I've wanted a big dog, truly big. And my wife surprised me for father's day 2 years ago with a puppy. And she grew fast. She is currently a little north of 220 lbs. She is spayed and microchipped and current on her shots. She is loving and playful and protective. She does drool a lot, but we got used to having a handful of "dog towels" around the house to just wipe up after her. And she's trained to come to me so I can clean her face after she drinks water.But unfortunately, I am in the military and live in military housing, and now we have to move, and won't be able to bring her.Please understand that this is not easy, I do not want to give her up, but she's a good girl and deserves a good home.

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These pups are in El Cajon, California too!

Below are our newest added Mastiffs available for adoption in El Cajon, California. To see more adoptable Mastiffs in El Cajon, California, use the search tool below to enter specific criteria!
Photo of Nellie

Nellie

German Shepherd Dog Bullmastiff

Female, Senior
El Cajon, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Not good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Nellie is a well trained dog. She is very loving and sweet and a great watchdog. She sits, stays, shakes, and in her younger years, she would also roll over. She gets along great with small dogs and cats (we have two), but not large dogs as she tries to show her dominance with large dogs. She has developed some stiffness in her joints as she has aged. And she has a benign growth the size of an orange on her side. But no other known health issues. She eats Blue Buffalo dog food, along with nubs and other treats. My mother has early dementia and she recently moved in with us. She also has two dogs. My husband and I are completely overwhelmed, we both have MS, and we just can't take care of Nellie anymore. We're looking to re-home her so she can get the love and attention that she deserves and needs.

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in El Cajon, California.

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Mastiff puppies and dogs in nearby cities

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Related breeds in El Cajon, California

Bullmastiffs in El Cajon, California Neapolitan Mastiffs in El Cajon, California Saint Bernards in El Cajon, California

Mastiff shelters & rescues in El Cajon, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in El Cajon, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

5.4 miles

San Diego Humane Society - El Cajon Campus

1373 N. Marshall Ave., El Cajon, CA 92020

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

11.6 miles

Chula Vista Animal Care Facility (public)

130 Beyer Way, Chula Vista, CA 91911

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Shelter

17 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

19.4 miles

Second Chance Dog Rescue

4284 Cass Street, San Diego, CA 92109

Pet Types: dogs

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Rescue

19.6 miles

Rescue Fenix

San Diego, CA 92192

Pet Types: cats, dogs

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Shelter

30.7 miles

Rancho Coastal Humane Society

389 Requeza Street, Encinitas, CA 92024

Pet Types: cats, dogs, rabbits, small animals

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Rescue

32.9 miles

Saving Shelter Pets of CA

San Marcos, CA 92069

Pet Types: dogs

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Rescue

37.3 miles

Amazing Dogs

Carlsbad, CA 92011

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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