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Mastiff puppies and dogs in El Cajon, California

Looking for a Mastiff puppy or dog in El Cajon, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in El Cajon, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near El Cajon, California

These Mastiffs are available for adoption close to El Cajon, California.
We'll also keep you updated on Sunflower's adoption status with email updates.
Photo of Sunflower

Sunflower

Mastiff Boxer

Female, Adult
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by a community member on December 23, 2025. Why this pet is the one for you:Despite her shyness, Sunflower is full of affection to give. Once warming up she becomes a big cuddly companion, seeking nothing more than a cozy lap and lots of love. Her playful side emerges while chasing toys and during games in the yard. Past the timid surface Sunflower's sweet nature makes her a delightful friend for those seeking a loyal and loving pet. At SDHS:This pet has been vaccinated, microchipped and spayed. This pet is now ready for their new home! Primary Color: Black Weight: 74 Age: 3yrs 2mths 1wks
We'll also keep you updated on Nala's adoption status with email updates.
Photo of Nala

Nala

Mastiff Cane Corso

Female, Young
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Nala is a beautiful 4-year-old large breed mix (Cane Corso type), approximately 120 lbs, with a loyal and affectionate personality. She is fully house-trained and understands basic commands such as “sit” and “stay,” responding to both Spanish and English. She has a gentle and patient temperament, especially with children. Our two-year-old daughter has grown up with her, and Nala has always been loving and careful around little ones. She is friendly with other dogs and enjoys playful interactions. Despite her size, she has a soft, playful side — she loves carrying her stuffed toys and being close to her people. She is naturally protective but not overly reactive, barking only when appropriate. She is spayed and up to date on all vaccinations. Due to changes in our family circumstances, we are seeking a stable, loving home where she can receive consistent attention, companionship, and care. $150 rehoming fee applies to ensure serious inquiries.
We'll also keep you updated on Atlas's adoption status with email updates.
Photo of Atlas

Atlas

Mastiff

Male, Puppy
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
-
We'll also keep you updated on Gus's adoption status with email updates.
Photo of Gus

Gus

English Mastiff

Male, 6 yrs 10 mos
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Gus Gus is an 8-year-old black Mastiff with a heart as big as his paws. Found as a stray in Ontario alongside his friend—possibly his daughter—Tavi, Gus has shown nothing but gentle, loving energy. While they would love to find a home together, they can be adopted separately if needed. Weighing in at approximately 115 lbs, Gus is a true gentle giant. He’s the sweetest big boy who lives for chew sticks, affection, and cozy snuggles. Gus would be perfectly happy spending his days as a couch potato, soaking up love and giving it right back. He is housetrained and has wonderful manners, making him an easy, loving companion for a calm home looking for a loyal best friend. ##2648733##

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in El Cajon, California.

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Mastiff shelters & rescues in El Cajon, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in El Cajon, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

17 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

19.6 miles

Rescue Fenix

San Diego, CA 92192

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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