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Mastiff puppies and dogs in Poway, California

Looking for a Mastiff puppy or dog in Poway, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Poway, California Other pups in Poway, California Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Poway, California Mastiff shelters and rescues in Poway, California Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Poway, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Poway, California

These Mastiffs are available for adoption close to Poway, California.
We'll also keep you updated on Opal's adoption status with email updates.
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Opal

Mastiff

Female, Adult
Escondido, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How Opal arrived: Opal was brought in by our Humane Law Enforcement team on January 18, 2026. Why Opal is the one for you:Opal is a big, beautiful bundle of sweetness with a heart as soft as her name suggests. Though the world can feel scary to her at times, she faces it with gentle bravery-especially when a little cheese is involved. At 113 pounds of pure love, Opal's warmth is felt in every slow tail wag and trusting lean. Her sensitivity, affection, and cheese-powered courage make her an unforgettable, lovable soul. At SDHS:Opal has been vaccinated, microchipped and neutered. Opal is now ready for her new home! Primary Color: Black Brindle Weight: 116.6 Age: 4yrs 1mths 1wks

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We'll also keep you updated on Gus's adoption status with email updates.
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Gus

English Mastiff

Male, 6 yrs 10 mos
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Gus Gus is an 8-year-old black Mastiff with a heart as big as his paws. Found as a stray in Ontario alongside his friend—possibly his daughter—Tavi, Gus has shown nothing but gentle, loving energy. While they would love to find a home together, they can be adopted separately if needed. Weighing in at approximately 115 lbs, Gus is a true gentle giant. He’s the sweetest big boy who lives for chew sticks, affection, and cozy snuggles. Gus would be perfectly happy spending his days as a couch potato, soaking up love and giving it right back. He is housetrained and has wonderful manners, making him an easy, loving companion for a calm home looking for a loyal best friend. ##2648733##

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We'll also keep you updated on Jughead's adoption status with email updates.
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Jughead

Mastiff American Staffordshire Terrier

Male, 2 yrs 11 mos
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Meet Jughead! DOB: March 2023Weight: 70lbsDisposition: Jughead is a friendly and curious boy who loves nothing more than exploring the outdoors. He's a natural on the trails and is working on his leash manners so he can be the best hiking partner possible. When he's not adventuring, he's busy with his toys, treating them with a surprising amount of care before he finally lets loose and has a blast. He loves his people and is looking for someone who can help him work on building his focus and attention span.History: Rescued from a shelter in LA County by TBL in March 2025Best Home: A family (or single person) looking for a loyal companion to join you on your adventures and a sweet boy to cuddle up with at the end of the day.Amazing Qualities: Jughead is curious and confident! He's ready to explore the world.If you're interested in meeting this dog, please visit our website to fill out an adoption application: www.thebarkinglot.net/adoptOur dogs are located in San Diego County, CA. We will happily consider out of town applications and can conduct virtual play dates with interested adopters. We have monthly transport to various locations in the Pacific Northwest, individual arrangements would need to be made for other locations across the US and Canada.To initiate the adoption process for this dog, please complete our online application by clicking below. Your adoption coordinator will respod to you via email once they receive your application: www.thebarkinglot.net/adopt

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We'll also keep you updated on Sunflower's adoption status with email updates.
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Sunflower

Mastiff Boxer

Female, Adult
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by a community member on December 23, 2025. Why this pet is the one for you:Despite her shyness, Sunflower is full of affection to give. Once warming up she becomes a big cuddly companion, seeking nothing more than a cozy lap and lots of love. Her playful side emerges while chasing toys and during games in the yard. Past the timid surface Sunflower's sweet nature makes her a delightful friend for those seeking a loyal and loving pet. At SDHS:This pet has been vaccinated, microchipped and spayed. This pet is now ready for their new home! Primary Color: Black Weight: 74 Age: 3yrs 2mths 0wks

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We'll also keep you updated on Nala's adoption status with email updates.
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Nala

Mastiff Cane Corso

Female, Young
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Nala is a beautiful 4-year-old large breed mix (Cane Corso type), approximately 120 lbs, with a loyal and affectionate personality. She is fully house-trained and understands basic commands such as “sit” and “stay,” responding to both Spanish and English. She has a gentle and patient temperament, especially with children. Our two-year-old daughter has grown up with her, and Nala has always been loving and careful around little ones. She is friendly with other dogs and enjoys playful interactions. Despite her size, she has a soft, playful side — she loves carrying her stuffed toys and being close to her people. She is naturally protective but not overly reactive, barking only when appropriate. She is spayed and up to date on all vaccinations. Due to changes in our family circumstances, we are seeking a stable, loving home where she can receive consistent attention, companionship, and care. $150 rehoming fee applies to ensure serious inquiries.

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We'll also keep you updated on Atlas's adoption status with email updates.
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Atlas

Mastiff

Male, Puppy
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Poway, California.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Poway, California

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Mastiff shelters & rescues in Poway, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Poway, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

12.4 miles

Rescue Fenix

San Diego, CA 92192

Pet Types: cats, dogs

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Shelter

12.5 miles

San Diego Humane Society - Escondido Campus

3500 Burnet Drive, Escondido, CA 92027

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

13.1 miles

The Barking Lot

San Diego, CA 92117

Pet Types: dogs

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Shelter

16.3 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

21.3 miles

Passion for Pitties

P.O. Box 212574, Chula Vista, CA 91921

Pet Types: dogs

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Rescue

39.9 miles

Angel Dog Alliance, NFP (CA)

Temecula, CA 92591

Pet Types: dogs

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Shelter

46.1 miles

Animal Friends of the Valleys

33751 Mission Trail, Wildomar, CA 92595

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

46.1 miles

All Paws K9 Rescue

Winchester, CA 92595

Pet Types: cats, dogs, horses

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Rescue

46.4 miles

Hope Ranch Animal Sanctuary

Anza, CA 92539

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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