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Mastiff puppies and dogs in Poway, California

Looking for a Mastiff puppy or dog in Poway, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Poway, California Other pups in Poway, California Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Poway, California Mastiff shelters and rescues in Poway, California Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Poway, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Poway, California

These Mastiffs are available for adoption close to Poway, California.
Photo of Kane

Kane

Mastiff

Male, Adult
El Cajon, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by a community member May 14, 2026. Why this pet is the one for you:Meet Kane, a sweet and gentle pup looking for a loving new home! Kane can be a bit shy with new faces and spaces and appreciates some extra time to build trust. Once he feels comfortable, he blossoms into a laid-back, easygoing companion. Kane is a smart, curious canine who is excited to learn new tricks, explore new environments and get plenty of sniffs in on walks. Because of Kane's shy nature, he may thrive best in a lower-traffic household. If you're ready to give Kane the love and care he deserves, speak to an adoption counselor to learn more today! At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for adoption! Primary Color: Black Weight: 104 Age: 4yrs 0mths 2wks

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Photo of Skadi

Skadi

Mastiff

Female, Adult
Escondido, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
How Skadi arrived: Skadi was brought in by their previous owner on March 15th. Why Skadi is the one for you:Skadi is a beautiful gentle giant with a heart just as big as her size. Though she may be a little shy when you first meet her, it doesn't take long for her sweet and loving nature to shine through. She's calm, patient, and wonderfully gentle, making her a great companion for kids who can appreciate her soft and easygoing personality. Skadi thrives in a low-energy home where she can feel safe and relaxed, and she would do best as the only dog or with another very calm, laid-back companion. Once she bonds with you, Skadi will fill your days with quiet affection, loyal companionship, and the kind of warmth only a truly special dog can give. At SDHS:Skadi has been vaccinated, microchipped and spayed. Skadi is now ready for their new home! Primary Color: Tan Weight: 103 Age: 3yrs 3mths 3wks

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Photo of Octavia

Octavia

English Mastiff

Female, 7 yrs 1 mo
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Octavia also called Tavi. Octavia is a big girl with an even bigger heart. Since being rescued from the shelter, she’s proven herself to be the perfect houseguest—gentle, loving, and so grateful for a second chance. Affectionately known as Tavi, she’s ready to leave her past behind and find a forever home where she can truly shine. She just needs someone to give her that chance… and we know she’ll give a lifetime of love in return. Due to Tavi's neglect, she had a severe eye infection when we rescued her from the shelter on the euth list.  Unfortunately, we were unable to save her eye but that doesn't stop her one bit! ##2688495##

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'SAVE MY LIFE'

Mastiff

Male, 8 mos
San Marcos, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
WE ARE COURTESY POSTING THIS DOG FOR THE MORENO VALLEY ANIMAL SHELTER TO HELP THEM FIND A HOME. The shelter is severely overcrowded and desperately needs help finding adopters. Dogs are being turned in higher numbers than the shelter can accommodate; therefore, many are losing their lives simply due to a lack of cage space. We are helping get the word out about their immediate need. Please save this deserving pooch and clear a kennel for another dog in need today! This beautiful dog is located in the Moreno Valley shelter. Shelter needs to clear the kennels. They are over capacity, and all available dogs are in urgent need. Please visit or email the shelter directly to adopt. LEONARDO - ID#A550856 Shelter staff named me LEONARDO, and I am a neutered male, black brindle and white Mastiff mix. The shelter thinks I am about 8 months old I weigh approximately 63.10 lbs. SEE MORE VIDEOS AND PHOTOS HERE: https://myalbum.com/album/UjDVDuxootLhaY/ STAFF NOTES: * Leonardo was Pet of the Week 05/13/2026 * Leonardo knows sit * Leonardo loves playing with toys * Leonardo walks well on a leash * Leonardo is doing well sharing a kennel with a male Pit Bull mix (BERNARDO - ID#A550859) Moreno Valley Animal Shelter 14041 Elsworth Street, Moreno Valley, CA 92553 951-413-3790 Adoption hours: Tuesday - Friday 10 am - 5 pm Saturday 10:30 am - 3:30 pm Closed Sunday-Monday & Holidays

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Photo of Awesome Sauce

Awesome Sauce

Mastiff

Male, Adult
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
How Awesome Sauce arrived:Awesome Sauce was brought in by our Humane Law Enforcement team on April 19, 2026. Why Awesome Sauce is the one for you:Meet Awesome Sauce, a big, lovable goofball who lives up to his name with a personality that is equal parts heart and hype. From the moment you meet him, he brings a whole lot of flavor to the table with his wiggly body, soft eyes and signature tail that whips with excitement when he sees his people. He bonds quickly and thrives on attention, always ready to soak up pets or stick close by your side. He walks well for the most part and enjoys sniffing and exploring, though he can get a bit amped up during transitions, such as leaving or returning to his kennel. When he's excited, he may jump or get a little mouthy, but he is already showing improvement and responds well to redirection and clear guidance. He does have a few medical considerations to keep in mind, including sun-related skin growths on his belly, an inward-rolling eyelid and a small growth on his chin that will need observation over time. This big boy will do best with an adopter who can help him continue working on his manners and give him outlets for his energy, along with plenty of companionship. If you're looking for a dog with a big personality, a bigger heart and just the right amount of zest, Awesome Sauce is ready to spice up your life. Please bring a leash & collar when adopting. At SDHS:Awesome Sauce has been vaccinated, microchipped and neutered.Excitable Dog: This pet requires a virtual behavior consult, please watch THIS video to learn more about them. Primary Color: Blue Weight: 99 Age: 6yrs 1mths 1wks

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Photo of Bubba

Bubba

Mastiff

Male, Senior
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
Primary Color: Brown Brindle Weight: 90 Age: 8yrs 0mths 0wks

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Poway, California.

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Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Carlsbad, CA Mastiff in Chula Vista, CA Mastiff in Coronado, CA Mastiff in El Cajon, CA Mastiff in Encinitas, CA Mastiff in Escondido, CA Mastiff in Imperial Beach, CA Mastiff in La Mesa, CA Mastiff in Lemon Grove, CA Mastiff in National City, CA Mastiff in Oceanside, CA Mastiff in San Diego, CA Mastiff in San Marcos, CA Mastiff in Santee, CA Mastiff in Solana Beach, CA Mastiff in Vista, CA

Related breeds in Poway, California

Bullmastiffs in Poway, California Neapolitan Mastiffs in Poway, California Saint Bernards in Poway, California

Mastiff shelters & rescues in Poway, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Poway, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

12.1 miles

San Diego Humane Society - El Cajon Campus

1373 N. Marshall Ave., El Cajon, CA 92020

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

12.4 miles

Rescue Fenix

San Diego, CA 92192

Pet Types: cats, dogs

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Shelter

12.5 miles

San Diego Humane Society - Escondido Campus

3500 Burnet Drive, Escondido, CA 92027

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

15.7 miles

Saving Shelter Pets of CA

San Marcos, CA 92069

Pet Types: dogs

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Shelter

16.3 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

27.2 miles

Baja Animal Sanctuary

P.O. Box 439060, PMB 626, San Diego, CA 92143

Pet Types: cats, dogs

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Rescue

39.9 miles

Angel Dog Alliance, NFP (CA)

Temecula, CA 92591

Pet Types: dogs

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Rescue

46.1 miles

All Paws K9 Rescue

Winchester, CA 92595

Pet Types: cats, dogs, horses

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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