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Mastiff puppies and dogs in Poway, California

Looking for a Mastiff puppy or dog in Poway, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Poway, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Poway, California

These Mastiffs are available for adoption close to Poway, California.
We'll also keep you updated on Priscillo's adoption status with email updates.
Photo of Priscillo

Priscillo

Mastiff

Male, Adult
Escondido, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by a community member on 2/12/26. Why this pet is the one for you:Priscillo is a sweet and sensitive dog who is still learning that the world can be a safe and kind place. He can be fearful when it comes to handling and new situations, so he needs a little extra time and understanding as he gets comfortable. While he may seem shy at first, Priscillo has a soft and loving personality that begins to shine once he feels secure.Meeting new people and exploring unfamiliar environments can be overwhelming for Priscillo. Because of this, he does best when introductions are slow and calm. With patience, gentle encouragement, and consistency, he gradually warms up and begins to show his affectionate and loyal nature. At SDHS:This pet has been vaccinated, microchipped and spayed neutered. This pet is now ready for their new home! Primary Color: Black Brindle Weight: 74 Age: 2yrs 1mths 1wks
We'll also keep you updated on Skadi's adoption status with email updates.
Photo of Skadi

Skadi

Mastiff

Female, Adult
Escondido, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
How Skadi arrived: Skadi was brought in by their previous owner on March 15th. Why Skadi is the one for you:Skadi is a beautiful gentle giant with a heart just as big as her size. Though she may be a little shy when you first meet her, it doesn't take long for her sweet and loving nature to shine through. She's calm, patient, and wonderfully gentle, making her a great companion for kids who can appreciate her soft and easygoing personality. Skadi thrives in a low-energy home where she can feel safe and relaxed, and she would do best as the only dog or with another very calm, laid-back companion. Once she bonds with you, Skadi will fill your days with quiet affection, loyal companionship, and the kind of warmth only a truly special dog can give. At SDHS:Skadi has been vaccinated, microchipped and spayed. Skadi is now ready for their new home! Primary Color: Tan Weight: 104 Age: 3yrs 1mths 2wks
We'll also keep you updated on Gus's adoption status with email updates.
Photo of Gus

Gus

English Mastiff

Male, 6 yrs 11 mos
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Gus Gus is an 8-year-old black Mastiff with a heart as big as his paws. Found as a stray in Ontario alongside his friend—possibly his daughter—Tavi, Gus has shown nothing but gentle, loving energy. While they would love to find a home together, they can be adopted separately if needed. Weighing in at approximately 115 lbs, Gus is a true gentle giant. He’s the sweetest big boy who lives for chew sticks, affection, and cozy snuggles. Gus would be perfectly happy spending his days as a couch potato, soaking up love and giving it right back. He is housetrained and has wonderful manners, making him an easy, loving companion for a calm home looking for a loyal best friend. ##2648733##
We'll also keep you updated on Octavia's adoption status with email updates.
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Photo of Octavia

Octavia

English Mastiff

Female, 6 yrs 11 mos
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Octavia also called Tavi. Octavia is a big girl with an even bigger heart. Since being rescued from the shelter, she’s proven herself to be the perfect houseguest—gentle, loving, and so grateful for a second chance. Affectionately known as Tavi, she’s ready to leave her past behind and find a forever home where she can truly shine. She just needs someone to give her that chance… and we know she’ll give a lifetime of love in return. Due to Tavi's neglect, she had a severe eye infection when we rescued her from the shelter on the euth list.  Unfortunately, we were unable to save her eye but that doesn't stop her one bit! ##2688495##
We'll also keep you updated on Sunflower's adoption status with email updates.
Photo of Sunflower

Sunflower

Mastiff Boxer

Female, Adult
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by a community member on December 23, 2025. Why this pet is the one for you:Meet Sunflower! Despite her initial shyness, Sunflower is full of affection to share. Once she warms up, she becomes a big cuddly companion, seeking nothing more than a cozy lap and lots of love. Her playful side emerges in the yard with toys and interactive games. With a patient and gentle adopter, Sunflower is ready to bloom into a delightful companion. If you're looking for a loyal and loving cuddle bug, Sunflower could be your perfect match! At SDHS:This pet has been vaccinated, microchipped and spayed. This pet is now ready for their new home! Primary Color: Black Weight: 74 Age: 3yrs 3mths 0wks
We'll also keep you updated on Atlas's adoption status with email updates.
Photo of Atlas

Atlas

Mastiff

Male, Puppy
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
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Mastiff shelters & rescues in Poway, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Poway, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

12.4 miles

Rescue Fenix

San Diego, CA 92192

Pet Types: cats, dogs

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Shelter

12.5 miles

San Diego Humane Society - Escondido Campus

3500 Burnet Drive, Escondido, CA 92027

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

16.3 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

39.9 miles

Angel Dog Alliance, NFP (CA)

Temecula, CA 92591

Pet Types: dogs

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Rescue

46.1 miles

All Paws K9 Rescue

Winchester, CA 92595

Pet Types: cats, dogs, horses

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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