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Mastiff puppies and dogs in Poway, California

Looking for a Mastiff puppy or dog in Poway, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Poway, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Poway, California

These Mastiffs are available for adoption close to Poway, California.
Photo of Astrid

Astrid

Mastiff American Pit Bull Terrier

Female, Young
Escondido, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
How this pet arrived:Astrid was brought in by their previous owner on June 3, 2026. Why this pet is the one for you: Astrid is a sweet and friendly dog looking for a loving home. According to her owner, she is a social companion who loves to play with other dogs and has previously done well living with both cats and children. Astrid also knows basic commands like "sit" and "stay," which highlights her bright personality. Since she can sometimes show some arousal and impulsivity when she's excited, she would benefit from a family that can offer her a structured routine and healthy outlets for her enthusiasm. Astrid flourishes in an environment that provides plenty of companionship, interactive play, and the steady guidance she needs to be her best self. She is ready to become a loyal and fun-loving member of her new family. At SDHS:Astrid has been vaccinated, microchipped and spayed. Astrid is now ready for adoption! Primary Color: Brindle Secondary Color: White Weight: 73.2 Age: 1yrs 0mths 2wks
Photo of Octavia

Octavia

English Mastiff

Female, 7 yrs 2 mos
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Octavia also called Tavi. Octavia is a big girl with an even bigger heart. Since being rescued from the shelter, she’s proven herself to be the perfect houseguest—gentle, loving, and so grateful for a second chance. Affectionately known as Tavi, she’s ready to leave her past behind and find a forever home where she can truly shine. She just needs someone to give her that chance… and we know she’ll give a lifetime of love in return. Due to Tavi's neglect, she had a severe eye infection when we rescued her from the shelter on the euth list.  Unfortunately, we were unable to save her eye but that doesn't stop her one bit! ##2688495##
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'SAVE MY LIFE'

Mastiff

Male, 1 yr 6 mos
San Marcos, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
WE ARE COURTESY POSTING THIS DOG FOR THE MORENO VALLEY ANIMAL SHELTER TO HELP THEM FIND A HOME. The shelter is severely overcrowded and desperately needs help finding adopters. Dogs are being turned in higher numbers than the shelter can accommodate; therefore, many are losing their lives simply due to a lack of cage space. We are helping get the word out about their immediate need. Please save this deserving pooch and clear a kennel for another dog in need today! This beautiful dog is located in the Moreno Valley shelter. The shelter needs to clear kennels. They are over capacity, and all available dogs are in urgent need. Please visit or email the shelter directly to adopt. PACO - ID#A551355 Shelter staff named me PACO, and I am a neutered male, brown and black Mastiff. The shelter thinks I am about 1 year and 6 months old. I weigh approximately 70.60 lbs. SEE MORE VIDEOS AND PHOTOS HERE: https://myalbum.com/album/XM6PgGQr5fuPAr/ STAFF NOTES: * Paco knows sit and shake * Paco appears to be potty trained * Paco loves toys * Paco enjoys sharing a kennel with a spayed Chinese Sharpei mix (Ariel A551354); they prefer to eat separately Moreno Valley Animal Shelter 14041 Elsworth Street, Moreno Valley, CA 92553 951-413-3790 Adoption hours: Tuesday - Friday 10 am - 5 pm Saturday 10:30 am - 3:30 pm Closed Sunday-Monday & Holidays
Photo of Awesome Sauce

Awesome Sauce

Mastiff

Male, Adult
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
How Awesome Sauce arrived:Awesome Sauce was brought in by our Humane Law Enforcement team on April 19, 2026. Why Awesome Sauce is the one for you:Meet Awesome Sauce, a big, lovable goofball who lives up to his name with a personality that is equal parts heart and hype. From the moment you meet him, he brings a whole lot of flavor to the table with his wiggly body, soft eyes and signature tail that whips with excitement when he sees his people. He bonds quickly and thrives on attention, always ready to soak up pets or stick close by your side. He walks well for the most part and enjoys sniffing and exploring, though he can get a bit amped up during transitions, such as leaving or returning to his kennel. When he's excited, he may jump or get a little mouthy, but he is already showing improvement and responds well to redirection and clear guidance. He does have a few medical considerations to keep in mind, including sun-related skin growths on his belly, an inward-rolling eyelid and a small growth on his chin that will need observation over time. This big boy will do best with an adopter who can help him continue working on his manners and give him outlets for his energy, along with plenty of companionship. If you're looking for a dog with a big personality, a bigger heart and just the right amount of zest, Awesome Sauce is ready to spice up your life. Please bring a leash & collar when adopting. At SDHS:Awesome Sauce has been vaccinated, microchipped and neutered.Excitable Dog: This pet requires a virtual behavior consult, please watch THIS video to learn more about them. Primary Color: Blue Weight: 99 Age: 6yrs 2mths 0wks
Photo of Bonbon

Bonbon

Mastiff Catahoula Leopard Dog

Female, Adult
San Diego, CA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by our Humane Law Enforcement team on June 15, 2026. Why this pet is the one for you: Say hello to Bonbon! We are still learning about Bonbon's unique personality, but we would be happy to introduce you to her to see if she is a good fit for your family. Bonbon is a friendly, affectionate pup who greets everyone she meets with a wagging tail and heartwarming smile. Bonbon is a laid-back, easygoing pup who's perfectly content to join you for a leisurely stroll or cuddle up for a long nap. If you'd like to meet this loving pup, speak with our team today! At SDHS:This pet has been vaccinated, microchipped and spayed. This pet is now ready for adoption! Primary Color: Brindle Secondary Color: Black Weight: 64 Age: 4yrs 0mths 1wks
Photo of Bonehead

Bonehead

Mastiff Catahoula Leopard Dog

Male, Adult
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by our Humane Law Enforcement team on June 15, 2026. Why this pet is the one for you: Say hello to Bonehead! We are still learning about Bonehead's unique personality, but we would be happy to introduce you to him to see if he is a good fit for your family. Bonehead is a smart, curious canine who is excited to learn new tricks, explore new environments and get plenty of sniffs in on walks. He would love to find a family that can give him all of the activity and affection he needs. If you'd like to meet this handsome pup, speak with our team today! At SDHS:This pet has been vaccinated, microchipped and neutered. This pet is now ready for adoption! Primary Color: Brindle Secondary Color: Black Weight: 61 Age: 4yrs 0mths 1wks

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Poway, California.

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Mastiff shelters & rescues in Poway, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Poway, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

12.4 miles

Rescue Fenix

San Diego, CA 92192

Pet Types: cats, dogs

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Shelter

12.5 miles

San Diego Humane Society - Escondido Campus

3500 Burnet Drive, Escondido, CA 92027

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

15.7 miles

Saving Shelter Pets of CA

San Marcos, CA 92069

Pet Types: dogs

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Shelter

16.3 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

20.9 miles

Amazing Dogs

Carlsbad, CA 92011

Pet Types: dogs

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Rescue

27.2 miles

Baja Animal Sanctuary

P.O. Box 439060, PMB 626, San Diego, CA 92143

Pet Types: cats, dogs

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Rescue

39.9 miles

Angel Dog Alliance, NFP (CA)

Temecula, CA 92591

Pet Types: dogs

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Rescue

46.1 miles

All Paws K9 Rescue

Winchester, CA 92595

Pet Types: cats, dogs, horses

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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