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Mastiff puppies and dogs in San Diego, California

Looking for a Mastiff puppy or dog in San Diego, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in San Diego, California

These Mastiffs are available in San Diego, California.
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Photo of Georgia

Georgia

Mastiff Labrador Retriever

Female, Adult
San Diego, CA
Size
(when grown) -
Details
Not good with kids, Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by a Good Samaritan. Why this pet is the one for you:Do you like stuffed toys, pool time, tennis balls, and cozy blankets? Chewy bones and Kong toys are a plus! Milk bones and Pup-Peroni treats are also nice! Wait...since when do dogs know how to type?? The girl with the dazzling personality and apparently proficient computer skills is Georgia! Georgia is a bashful lady who is looking for a family to share all of her favorite things. Sounds like a dream, right? Well, it sounds like Georgia's dream and we think that Georgia IS a dream, so everyone is happy! Georgia has easily become a staff favorite with her caregivers and trainers. We just adore her goofy, sweet, affectionate, and playful personality. There's more that we're loving about this girl each day, and we can't wait to share more with you. Give us a call to schedule a behavior consultation with her trainer today! SPONSORED FEEGreat news! This pet has been sponsored! This means that the adoption fee has already been paid for by someone who wants to help this pet find a cherished home. Primary Color: Brindle Weight: 74.2 Age: 2yrs 3mths 3wks
Photo of Athena

Athena

Mastiff

Female, Adult
San Diego, CA
Size
(when grown) -
Details
Not good with kids, Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by previous owner. At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for their new home! Why this pet is the one for you:Meet Athena! Athena is a gentle soul, she can be very shy and will need patience and understanding from her new owner. Athena would thrive best in a quite and calm environment.  Do you want to love and support Athena? Come and adopt her today! Don'tdon't forget her new leash and collar. Primary Color: Black Brindle Secondary Color: White Weight: 72.2 Age: 2yrs 1mths 2wks
Photo of Wallace aka Wally

Wallace aka Wally

Mastiff American Pit Bull Terrier

Male, 3 yrs 10 mos
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Wally is just undeniably lovable! He has a smooshy face, he’s equal parts mellow and playful, loves all dogs, and LOVES people. Despite his large size, he is great with all dogs - big and small! He’s about 2-3 years old, neutered, and up to date on vaccines. He’s gained some weight since leaving the shelter and still needs a few more lbs. He’s a big time snuggler and would really love to share your bed if he’s allowed. But he’s looking good and looking for his forever! 🩵
Photo of Remy

Remy

Mastiff American Pit Bull Terrier

Male, 3 yrs 10 mos
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Remy (formerly Chato of East Valley Shelter in Los Angeles) is a big sweetheart. He was terribly frightened during his time at the shelter and has been so happy to be living in his wonderful foster home. He has an adorably big overbite and a very slight cleft palate, both of which add to his charm. Remy does well with large and small dogs, and has been learning basic training with his foster mom - where he has proven to be a quick learner! Remy loves to play as much as he loves to snuggle on the sofa. Do you have some extra room for this hunk in your heart?

Or, how about these Mastiffs in cities near San Diego, California

These Mastiffs are available for adoption close to San Diego, California.
Photo of RAYNA

RAYNA

Mastiff

Female, 4 yrs 5 mos
Chula Vista, CA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
Meet Rayna! Rayna here is a big time cuddlebug looking for her new life and forever home. Big silly energy with an adventurous spirit looking for an active home full of fun. Come down and see if Rayna would fit in with your family.
Photo of Tiggy

Tiggy

Mastiff

Female, Young
Poway, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Tiggy was born and raised in our home. Our other two dogs are her parents. The fawn colored dog in the pictures is her mother she is half German shepherd and 1/4 English mastiff and 1/4 French mastiff. The father (reverse brindle) is pure bred English mastiff. She was born with 9 other brothers and sisters. She has never been alone so I think it would be best if she was adopted into a home with other dogs. We have cats and when she’s inside she’s fine around them but when outside they play at the window with each other. She was also raised around our 4 boys aged 1-8 years old. We have to rehome her because her mother dog (Zuma) is being aggressive with her. Tiggy is very loving and sweet and I don’t want her to get hurt. We got them both fixed and have still not seen any improvement with Zuma’s aggression towards her. Hoping to find Tiggy a loving home!
Photo of BlackJack

BlackJack

Mastiff

Male, 3 yrs 10 mos
Jamul, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
House-trained, Spayed or Neutered, Shots are up-to-date,
Story
BlackJack is a fun, lovable big pup. He loves to play fetch, enjoys wading in water, knows sit, down, stay, and he has the cutest puppy-dog face!
Photo of Freeway

Freeway

Mastiff

Female, 1 yr 6 mos
Encinitas, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Freeway, the gentle soul who deserves a second chance at finding a loving family of her own. Freeway has shown her resilience and loving nature despite facing hardship. Found on the streets of Tijuana with her 5 puppies, Freeway unfortunately lost her little ones. Now, she's ready to embark on a new chapter and fill a home with her sweetness and love. Freeway is very affectionate, getting along well with other dogs and is content to be a couch potato, enjoying quiet moments with her loved ones. If you're ready to offer Freeway the love and security she deserves, she's eagerly waiting to become a cherished member of your family. ##2016011##
Photo of Woody

Woody

Mastiff

Male, Senior
Ramona, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Meet Woody! Woody came to us from West Valley Shelter-LA on November 29th. He is 8 years old, and although he weighs 124 lbs., he is the gentlest of giants. Since January, Woody has been living in a Foster home alongside a chihuahua and two cats, and according to his Foster Mom, he has been "amazing with them since the beginning. Here her full report on what life with Woody is like: "Woody is such a funny, sweet, goofy, and good dog! He has been great with all people he's met. He has only had brief interactions with kids in the neighborhood, but he has been totally accepting of little hands petting his face. Woody isn't overly affectionate with us. He doesn't lick us and seems indifferent to being pet. However, he shows he loves us in other ways! When we get home from work or when he first sees us in the morning, his tail wags and he goes for his toys. He also follows us from room to room all day. Woody lives with our chihuahua and two cats, and he has been amazing with them from the beginning. He naps much of the day, but he gets a burst of energy a couple times a day! During his high energy times, Woody loves to play with toys and fetch his ball. He enjoys short walks and he walks very slow (except for when he needs to potty, then he speed walks until he finds the perfect spot!) Woody has a seizure disorder, and thankfully, his seizures are currently well controlled by medications which he takes twice a day. He loooves taking meds because that means treats! He takes them happily in lunch meat, wet food, or cream cheese. Thank goodness for all the support Frosted Faces provides for their dogs! As a result of these medications , Woody is pretty clumsy and uncoordinated, and he bumps into things. We have stairs, and he can manage them for now. However, I do think a single story home might be best for Woody long term, unless his family could one day carry a 124 lb. dog up the stairs! Woody loves baking in the sunlight! If it's sunny outside, he will sometimes cry at the door for us to let him out onto the porch to sunbathe. He would love a spot to do this in his forever home. Woody has so many funny quirks that his family will fall in love with, and I hope they find him soon. I love to tell him he is a total sweetheart, because he is!"
Photo of Talula

Talula

Mastiff

Female, Senior
Ramona, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Talula! Talula was surrendered by her owner to Palmdale Shelter. Dogs at this facility only have a short time to be adopted or become at risk for euthanasia, due to the steady flow of incoming pets. We scooped up Talula on March 5th to become a Frosted Face. She is 9 years old and weighs 74 lbs. She is spunky, happy, friendly, and well-mannered. Talula had a kennelmate at the shelter that she got along great with, and she does well making friends at FFF. Talula hiked 2.25 miles at her first weekly hike - don't let her frosted face fool you! The volunteer who hiked with Talula shared this rave review afterwards: "Talula is really awesome! She's a gentle big, very polite with every dog and human we passed on the trail. She was curious about the dogs ahead or behind us, but as we passed them she was perfectly polite. Talula is really sweet, leaned into my legs when we paused along the trail, takes treats gently, and likes to be pet. And she's gorgeous! I'm sure she would like to take daily walks for sniffs and exercise." Talula lives in a Foster home, and we are so happy she is being loved and pampered while she waits for her forever family. We received a great update from her Foster Mom: "Talula is wrapping up her 3rd week with us! She's such a great doggo and is really starting to get comfortable in our house. She adores my husband, but definitely has started seeking me out first (which really makes me smile). Talula is great with our little dogs and has even started doing a small amount of awkward playing with our younger guy! She trots to the door for pets when I get home from work, and it honestly melts my heart. Now that she's comfortable, we notice she spends more time with us and, though still enjoys walks, seems like she's in a hurry to get back to hang out. Last weekend, Talula visited her first brewery with us and was a champion in meeting all of the humans and dogs that we saw!" Check back soon for the next update on how sweet Talula is doing!

These pups are in San Diego, California too!

Below are our newest added Mastiffs available for adoption in San Diego, California. To see more adoptable Mastiffs in San Diego, California, use the search tool below to enter specific criteria!
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Photo of Leo

Leo

Neapolitan Mastiff

Male, Adult
San Diego, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Leo is a gorgeous neapolitan mastiff.  His ideal home would be a home with someone who knows the breed and can set boundaries for him to thrive. He has the potential to do well with other dogs as long as the other dogs have good temperament. He was fostered with kids who were 12 years of age and he did good with them. Come meet sweet Leo if you are looking for a gorgeous large boy. Leo's adoption fee includes training. April 25, 2024, 5:29 pm
Special Needs
Photo of Hippo

Hippo

Bullmastiff

Male, Adult
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Needs special attention, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Your Gentle Giant Looking for Love! Hello there, I'm Hippo, a 4-year-old Bull Mastiff mix, a big boy at 92 lbs, and neutered. I was pulled from the Riverside shelter by TAP and I am so grateful for that! I have picked up bathroom manners, working on leash manners. I have separation  anxiety and current medications to help with separation anxiety include Trazodone (~$7.00), Gabapentin (~$13.00), Acepromazine as needed (~$25.00), and Prozac (~$5.00). Monthly cost depending on where purchased and market value.  I may look imposing at first glance, but once you get to know me, you'll see I'm the sweetest and most loveable companion you could ever ask for. I love affection, and snuggling up next to my humans is one of my favorite pastimes. I'm generally friendly with other dogs, but I might need a slow introduction to make sure we're all on the same page. When I'm inside the house, I sometimes get a bit anxious and bark at people passing by, but don't worry – once we're outside, I'll mostly be an observer, calmly taking in the world around me. I can show some leash reactivity though. With some patience, understanding, and positive reinforcement training, I'm sure I can overcome this behavior. I adore outdoor adventures and walks, but I can get a little distracted if there's too much going on around me. I find night walks with minimal distractions to be the best for me. That way, I can focus on our quality time together without getting overwhelmed by everything happening around us. One of my quirks is that I like to playfully bite ankles and wrists when I want to wake you up or just engage in some playtime. I promise it's all in good fun! But for this reason, a family with older kids or adults might be a better fit for me. I would absolutely love a fun-loving home with a yard! Having a safe and secure place to play and explore would make me one happy pup! I'm quite adaptable, so whether you lead an active lifestyle or prefer a more laid-back approach, I'll fit right in. Just as long as I get plenty of love and attention, I'll be content. So, are you ready to open your heart and home to a gentle giant like me? I guarantee that with a little understanding, patience, and love, I'll be the most loyal and loving companion you could ever wish for. Let's embark on this incredible journey together, creating unforgettable memories and forging an unbreakable bond. ##1733826##
Photo of Branch

Branch

Bullmastiff

Male, Adult
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
***URGENT*** MILITARY MOVING ON 9-15-23!!!!! I have a 6-year-old male bullmastiff-mix named Branch who I am looking to re-home. He is a 6-year-old male bullmastiff-mix, neutered, vaccinated and microchipped. He gets along great with adults, children, infants, and other dogs. His compatibility with cats is unknown. His temperament is snuggly and lazy, but he loves going on walks. He doesn’t play fetch or with toys often unless it is a pull toy (although he does play with a pull toy for a short period of time with us), he knows his basic commands, such as sit, stay, and come. He also loves going to dog parks, on walks, and for car rides. He is the sweetest soul ever. He couldn’t hurt anything, just wants to love and be with his family. He loves to watch and look over our baby and we trust him 100%. He’s silly, he’s friendly and loves to play with the neighborhood dogs. This dog is just perfect and would make a great addition for any family.❤️🐕💕 If anyone is interested in adopting Branch, please message us as soon as possible to schedule a meet-and-greet.

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Mastiff shelters & rescues in San Diego, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in San Diego, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

5.4 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

5.4 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

8.9 miles

Chula Vista Animal Care Facility (public)

130 Beyer Way, Chula Vista, CA 91911

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

13.4 miles

Mad Mutts

San Diego, CA 92126

Pet Types: dogs

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Rescue

13.4 miles

Mad Mutts

San Diego, CA 92126

Pet Types: dogs

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Rescue

18.3 miles

Rescuing Cujo

PO Box 81, Jamul, CA 91935

Pet Types: dogs

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Rescue

24.7 miles

Tragic To Magic - La Jolla

453 Encinitas Blvd, Encinitas, CA 92024

Pet Types: cats, dogs

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Rescue

26 miles

Frosted Faces Foundation

1448 Pine St, Ramona, CA 92065

Pet Types: cats, dogs

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Rescue

26 miles

Frosted Faces Foundation

1448 Pine St, Ramona, CA 92065

Pet Types: cats, dogs

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Rescue

31.8 miles

Amazing Dogs

Carlsbad, CA 92011

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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