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Mastiff puppies and dogs in Escondido, California

Looking for a Mastiff puppy or dog in Escondido, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Escondido, California Other pups in Escondido, California Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Escondido, California Mastiff shelters and rescues in Escondido, California Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Escondido, California

These Mastiffs are available in Escondido, California.
We'll also keep you updated on Barbara's adoption status with email updates.
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Barbara

Mastiff

Female, Adult
Escondido, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
NOT AVAILABLE AT THIS TIMEThis pet not currently available for adoption. This pet was brought in by Humane Law Enforcement on January 18, 2026. Please take a moment to go and see our many other adoptable friends!  Primary Color: Blue Weight: 106.6 Age: 5yrs 0mths 1wks

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We'll also keep you updated on Opal's adoption status with email updates.
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Opal

Mastiff

Female, Adult
Escondido, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How Opal arrived: Opal was brought in by our Humane Law Enforcement team on January 18th. Why Opal is the one for you:Opal is a big, beautiful bundle of sweetness with a heart as soft as her name suggests. Though the world can feel scary to her at times, she faces it with gentle bravery-especially when a little cheese is involved. At 113 pounds of pure love, Opal's warmth is felt in every slow tail wag and trusting lean. Her sensitivity, affection, and cheese-powered courage make her an unforgettable, lovable soul. At SDHS:Opal has been vaccinated, microchipped and neutered. Opal is now ready for their new home! Primary Color: Black Brindle Weight: 113 Age: 4yrs 0mths 1wks

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Or, how about these Mastiffs in cities near Escondido, California

These Mastiffs are available for adoption close to Escondido, California.
We'll also keep you updated on Barbara's adoption status with email updates.
Photo of Barbara

Barbara

Mastiff

Female, Adult
Escondido, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
NOT AVAILABLE AT THIS TIMEThis pet not currently available for adoption. This pet was brought in by Humane Law Enforcement on January 18, 2026. Please take a moment to go and see our many other adoptable friends!  Primary Color: Blue Weight: 106.6 Age: 5yrs 0mths 1wks

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We'll also keep you updated on Opal's adoption status with email updates.
Photo of Opal

Opal

Mastiff

Female, Adult
Escondido, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How Opal arrived: Opal was brought in by our Humane Law Enforcement team on January 18th. Why Opal is the one for you:Opal is a big, beautiful bundle of sweetness with a heart as soft as her name suggests. Though the world can feel scary to her at times, she faces it with gentle bravery-especially when a little cheese is involved. At 113 pounds of pure love, Opal's warmth is felt in every slow tail wag and trusting lean. Her sensitivity, affection, and cheese-powered courage make her an unforgettable, lovable soul. At SDHS:Opal has been vaccinated, microchipped and neutered. Opal is now ready for their new home! Primary Color: Black Brindle Weight: 113 Age: 4yrs 0mths 1wks

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We'll also keep you updated on Jughead's adoption status with email updates.
Photo of Jughead

Jughead

Mastiff American Staffordshire Terrier

Male, 2 yrs 10 mos
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Jughead! DOB: March 2023Weight: 70lbsDisposition: Jughead is a friendly and curious boy who loves nothing more than exploring the outdoors. He's a natural on the trails and is working on his leash manners so he can be the best hiking partner possible. When he's not adventuring, he's busy with his toys, treating them with a surprising amount of care before he finally lets loose and has a blast. He loves his people and is looking for someone who can help him work on building his focus and attention span.History: Rescued from a shelter in LA County by TBL in March 2025Best Home: A family (or single person) looking for a loyal companion to join you on your adventures and a sweet boy to cuddle up with at the end of the day.Amazing Qualities: Jughead is curious and confident! He's ready to explore the world.If you're interested in meeting this dog, please visit our website to fill out an adoption application: www.thebarkinglot.net/adoptOur dogs are located in San Diego County, CA. We will happily consider out of town applications and can conduct virtual play dates with interested adopters. We have monthly transport to various locations in the Pacific Northwest, individual arrangements would need to be made for other locations across the US and Canada.To initiate the adoption process for this dog, please complete our online application by clicking below. Your adoption coordinator will respod to you via email once they receive your application: www.thebarkinglot.net/adopt

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We'll also keep you updated on Buttercup's adoption status with email updates.
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Buttercup

Mastiff Belgian Malinois

Female, 1 yr 3 mos
Temecula, CA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
Meet Buttercup – The Smart, Alert, and Sweet Girl Ready for Her Forever Home  Buttercup is the perfect mix of intelligence, curiosity, and sweetness! Born on 10/26/24, this Mastiff and Malinois mix is always alert and eager to learn, making her a great fit for an active home that will nurture her sharp mind. While she’s incredibly smart, Buttercup also has a gentle and loving side—she enjoys affection, playtime, and bonding with her humans. Like her littermates, she’s been with a trainer, well-socialized and potty trained, giving her a great foundation to thrive in her future home. Up to date on vaccines Intelligent, curious, and affectionate Crate trained and potty trained  If you’re looking for a smart and loving pup who will be your loyal companion, Buttercup is your girl! Apply to adopt or foster today—don’t forget to mention Buttercup’s name! Professionally trained in basics (sit, stay, walking on leash, etc) Foster-to-adopt option available  Got inquiries about Buttercup? Click here to fill out our inquiry form (this is not an application): https://petstablished.com/petlover/general_form/71282 ##2313586##

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We'll also keep you updated on Tiger's adoption status with email updates.
Photo of Tiger

Tiger

Mastiff Belgian Malinois

Male, 1 yr 3 mos
Temecula, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
Meet Tiger – The Confident Leader with a Heart of Gold!  Tiger is ready to lead his way into your heart! Born on 10/26/24, this sweet Mastiff and Malinois mix is a natural leader —confident and curious. But don’t let his strong presence fool you—he’s also incredibly lovable, affectionate, and eager to bond with his humans. Tiger is a well-rounded boy who enjoys both playtime and cuddles. He’s been well-socialized and is potty trained, making him a great addition to a loving home. Whether he’s leading the charge on a new adventure or snuggling up for some quality time, Tiger is the perfect balance of strength and sweetness. Up to date on vaccines  Confident, affectionate, and a great companion Crate trained and potty trained  Professionally trained in basics (sit, stay, walking on leash, etc) Foster-to-adopt option available If you’re looking for a brave, smart, and loving boy to be your loyal companion, Tiger is your perfect match! Apply to adopt or foster today—don’t forget to mention Tiger’s name! ##2313590##

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We'll also keep you updated on Toothless's adoption status with email updates.
Photo of Toothless

Toothless

Mastiff Belgian Malinois

Male, 1 yr 3 mos
Temecula, CA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
Meet Toothless – The Energetic, Goofy, and Strong Boy Ready for Adventure! Toothless has a personality as big as his playful heart! Born on 10/26/24, this sweet Mastiff and Malinois mix is bursting with energy, always ready to zoom around and explore the world with his goofy charm. He’s strong, confident, and full of fun, making him the perfect pup for an active household. Toothless is not just about high energy—he’s also a sweetheart who loves affection and human connection. Well-socialized, crate trained and potty trained, he’s a smart boy who will thrive in a home that gives him structure, love, and lots of playtime. Toothless is great on outings - check out his photos. Up to date on vaccines  Playful, strong, and always ready for fun Crate trained and potty trained Professionally trained in basics (sit, stay, walking on leash, etc) Foster-to-adopt option available If you’re looking for a goofy, adventurous, and lovable boy to keep you on your toes, Toothless is your guy! Apply to adopt or foster today—don’t forget to mention Toothless’ name! ##2313604##

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Escondido, California.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Escondido, California

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Mastiff shelters & rescues in Escondido, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Escondido, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

0 miles

San Diego Humane Society - Escondido Campus

3500 Burnet Drive, Escondido, CA 92027

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

23.2 miles

The Barking Lot

San Diego, CA 92117

Pet Types: dogs

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Shelter

27.2 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

27.4 miles

Angel Dog Alliance, NFP (CA)

Temecula, CA 92591

Pet Types: dogs

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Shelter

33.5 miles

PAWS of Coronado

1395 First Street, Coronado, CA 92118

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

33.7 miles

Passion for Pitties

P.O. Box 212574, Chula Vista, CA 91921

Pet Types: dogs

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Rescue

34.1 miles

All Paws K9 Rescue

Winchester, CA 92595

Pet Types: cats, dogs, horses

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Shelter

34.1 miles

Animal Friends of the Valleys

33751 Mission Trail, Wildomar, CA 92595

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

35.3 miles

Hope Ranch Animal Sanctuary

Anza, CA 92539

Pet Types: dogs

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Shelter

36.6 miles

Chula Vista Animal Care Facility (public)

130 Beyer Way, Chula Vista, CA 91911

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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