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Mastiff puppies and dogs in Escondido, California

Looking for a Mastiff puppy or dog in Escondido, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Escondido, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Escondido, California

These Mastiffs are available for adoption close to Escondido, California.
We'll also keep you updated on URGENT! SHELTER IS FULL's adoption status with email updates.
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URGENT! SHELTER IS FULL

Mastiff

Female, 7 yrs
San Marcos, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
URGENT - Shelter needs to clear kennels. Please save this dog's life! WE ARE COURTESY POSTING THIS DOG FOR THE MORENO VALLEY ANIMAL SHELTER TO HELP THEM FIND A HOME. The shelter is severely overcrowded and desperately needs help. Dogs are being turned in higher numbers than the shelter can accommodate, therefore many are losing their lives due to lack of cage space. We are helping get the word out of their immediate need. Please save this deserving pooch and clear a kennel for another dog in need today! This beautiful dog is located in the Moreno Valley shelter. Please feel free to reach out to us with questions. Thank you! SUGAR BABY #A541069 I am a spayed, female, blue and fawn Mastiff mix. The shelter thinks I am about 7 years old. I weigh approximately 110.00 lbs. VIDEOS: https://myalbum.com/album/tURmGddwp3mxo6/ STAFF NOTES: * Very sweet girl * Will lay down and roll over for belly rubs every chance she gets * Loves attention, pets and scratches. * Easy to leash and walk once out of the kennel * No aggression seen when walking by the other dogs. * She wants cuddles, belly rubs and being told what a good girl she is... because she is a great girl! Moreno Valley Animal Shelter 14041 Elsworth Street, Moreno Valley, CA 92553 951-413-3790 Adoption hours: Tuesday - Friday 10 am - 5 pm Saturday 10:30 am - 3:30 pm Closed Sunday-Monday & HolidaysURGENT! SHELTER IS FULLURGENT! SHELTER IS FULL
We'll also keep you updated on Cjay's adoption status with email updates.
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Cjay

Mastiff

Male, Senior
Carlsbad, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Goof, derp, lover of life. Cjay is loving, loyal, funny – a tongue flopping, trotting next to you kind of bestie. He’s a great hybrid dog who loves to enjoy the great outdoors and go on walks, play ball and bike ride.  But he also is a chill couch potato who likes to cozy in and watch TV.  Everyone who meets Cjay falls in love with him – he’s one of those dogs who doesn’t lack for personality haha and keeps you laughing. Cjay has been fostered by an awesome trainer so whoever adopts him will get a dog who has been through an in depth board and train program already. Cjay’s the right dog for an experienced family who are strong leaders with kind hearts to stay consistent with his training to continue to set him up for success. Approved adopters will receive training sessions so you know what Cjay knows to make the transition smooth :). Cjay’s favorite thing to do is play ball WHILE rolling in the grass at the same time 🤯 ❤️ He's available for adoption anywhere in SoCal.
We'll also keep you updated on Jughead's adoption status with email updates.
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Jughead

Mastiff American Staffordshire Terrier

Male, 2 yrs 9 mos
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Jughead! DOB: March 2023Weight: 70lbsDisposition: Jughead is a friendly and curious boy who loves nothing more than exploring the outdoors. He's a natural on the trails and is working on his leash manners so he can be the best hiking partner possible. When he's not adventuring, he's busy with his toys, treating them with a surprising amount of care before he finally lets loose and has a blast. He loves his people and is looking for someone who can help him work on building his focus and attention span.History: Rescued from a shelter in LA County by TBL in March 2025Best Home: A family (or single person) looking for a loyal companion to join you on your adventures and a sweet boy to cuddle up with at the end of the day.Amazing Qualities: Jughead is curious and confident! He's ready to explore the world.If you're interested in meeting this dog, please visit our website to fill out an adoption application: www.thebarkinglot.net/adoptOur dogs are located in San Diego County, CA. We will happily consider out of town applications and can conduct virtual play dates with interested adopters. We have monthly transport to various locations in the Pacific Northwest, individual arrangements would need to be made for other locations across the US and Canada.To initiate the adoption process for this dog, please complete our online application by clicking below. Your adoption coordinator will respod to you via email once they receive your application: www.thebarkinglot.net/adopt
We'll also keep you updated on Jones's adoption status with email updates.
Photo of Jones

Jones

Mastiff

Male, Young
San Diego, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
How this pet arrived:This pet was brought in by a community member on September 9, 2025. Why this pet is the one for you:Meet Jones! Jones is a total lovebug who's ready and waiting to find his new loving home. He adores people and will display his excited wiggles when he greets you. He can be a bit shy with new faces and places, but once he builds confidence, he'll share his playful and energetic side. He's very smart and treat motivated, and has already mastered "sit," "paw" and "down." Jones has been known to have big feelings around other dogs, and may do best as your one and only canine companion. Although he may not be a candidate for dog parks or other off-leash venues, there are lots of other activities you can do together to strengthen your bond! If you're interested in opening your heart and home to this sweet pup, come speak to an adoption counselor today!At SDHS:This pet has been vaccinated, microchipped and neutered. This pet is now ready for their new home!Dog Reactive Dog:  This pet requires a virtual behavior consult, please watch THIS video to learn more about them. Primary Color: Brown Secondary Color: Black Weight: 62.5 Age: 1yrs 3mths 0wks
We'll also keep you updated on Rigby's adoption status with email updates.
Photo of Rigby

Rigby

Mastiff

Male, 1 yr 11 mos
Winchester, CA
Size
(when grown) -
Details
-
Story
I am a fun, loving boy who loves to play. My only fault is I do not realize my size. I think I am a lap dog. I am house trained, and good with most other dogs. I would prefer to meet potential companions before going to a new home. ##2427887##
We'll also keep you updated on Fava's adoption status with email updates.
Photo of Fava

Fava

Mastiff Hound (Unknown Type)

Male, Puppy
Anza, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Shots are up-to-date,
Story
Meet Fava — the puppy with a zest for life (and maybe a little splash on the side). Born around April 4, 2025, this sweet, curious, and affectionate boy is ready to wiggle his way into your heart. Fava is in the prime of his puppyhood, which means two things: he’s got energy to spare and love to give. He’s smart, eager to learn, and the kind of pup who’s always up for whatever you’ve got planned — whether that’s road trip (preferably to the beach), a good splash in the water, or a cozy nap on the couch. He’s a social butterfly too! Fava loves other dogs, plays politely, and would thrive with a canine sibling. He also gets along beautifully with cats, making him a versatile companion for just about any home. At the end of the day, all Fava really wants is a family who will guide him with patience, give him plenty of love, and let him grow into the incredible dog he’s meant to be. In return, you’ll get loyalty, laughter, and a whole lot of puppy kisses. Looking for a fun-loving co-pilot who’s equal parts cuddle buddy and splash enthusiast? Fava just might be your guy.

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Escondido, California.

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Mastiff shelters & rescues in Escondido, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Escondido, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

7.5 miles

Saving Shelter Pets of CA

San Marcos, CA 92069

Pet Types: dogs

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Rescue

23.2 miles

The Barking Lot

San Diego, CA 92117

Pet Types: dogs

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Shelter

27.2 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

34.1 miles

All Paws K9 Rescue

Winchester, CA 92595

Pet Types: cats, dogs, horses

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Rescue

35.3 miles

Hope Ranch Animal Sanctuary

Anza, CA 92539

Pet Types: dogs

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Shelter

36.6 miles

Chula Vista Animal Care Facility (public)

130 Beyer Way, Chula Vista, CA 91911

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Shelter

47 miles

Riverside County Animal Control - San Jacinto Shelter

581 S. Grand Ave, San Jacinto, CA 92582

Pet Types: cats, dogs

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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