Mastiff Adoption in Vacaville, CA: Mastiff Puppies for Sale in Vacaville, CA

Adopt a Mastiff near you in Vacaville, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Vacaville, California

These Mastiffs are available for adoption close to Vacaville, California.

Rugby

Mastiff Cane Corso

Male, Young

Napa, CA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs, Spayed or Neutered,

Story

Rugby is a 1-year, 9-month-old Mastiff mix with a playful spirit and a sweet, sensitive side. He loves getting outside to run, play, and enjoy his toys, especially with his brother Romeo! Rugby can be shy with new people and unfamiliar places, but with a little patience, he begins to settle in and show his fun-loving personality. Primary Color: Tan Secondary Color: Black Weight: 74 Age: 1yrs 10mths 0wks

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Romeo

Mastiff Cane Corso

Male, Young

Napa, CA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Spayed or Neutered,

Story

Romeo is a 1-year, 9-month-old Mastiff mix with a playful, social personality! This big, handsome guy loves attention, playtime, and treats, and has done well meeting other dogs, including having a blast playing with his brother. Romeo is affectionate, food-motivated, and ready to bring lots of love (and plenty of play bows!) to his new family. Primary Color: Tan Secondary Color: Black Weight: 76 Age: 1yrs 10mths 0wks

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Stormi

Mastiff

Female, Young

Concord, CA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Not good with cats, House-trained, Spayed or Neutered,

Story

Stormi is a sweetheart! The only reason we are re homing her is because I’m a single mom and I don’t have the time to fully give her and I worry about her with my son due to her size and my son not having great boundaries. She has never bitten, she’s a quick learner and responds well to training! I want her to find her forever home, we’ve had her since she was 14weeks, she’s now 1yr 6 mo

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HERC

Mastiff

Male, Adult

Woodland, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Spayed or Neutered,

Story

No Greek Myth, Just a Really Great DogâÂÂCome Meet Herc. He is our hero. He came into the shelter as Hercules, but since we already had another dog by that name, he became Herc.Everyone who meets Herc seems to fall in love with him, and it's easy to see why. He has a huge heart and playful spirit and is just looking for someone to love. He does pull a bit on leash, but with a little training and consistency, he'll be absolutely legendary.You don't have to complete the Twelve Labors of Hercules to earn his love... just give him a forever home. I have a feeling he'll become the hero of someone's story.Come meet Herc and see for yourself why this gentle giant steals hearts wherever he goes. Every hero deserves a happy ending. Maybe you are the one to give it to him...Make an appointment to meet our strong man through yoloshelter.org/dogs, or email adopt@yoloshelter.org.September 5, 2026, 10:52 pm

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Chance

Mastiff American Staffordshire Terrier

Male, 1 yr 6 mos

Sacramento, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

🚨 CHARMING CHANCE -FINAL PLEA SURVIVOR LOOKING FOR HIS "FOREVER" 🚨Foster Home in Elk Grove/Sacramento County. 📞 Call 774-641-1955 or email SacCaninePlacementAssistance@gmail.com for more info or an adoption application.❤️ Chance's Fosters LOVE him but cannot keep him. ❤️🌟 Meet Chancellor (aka Chance)! This one-year-old puppy is full of life, love, and smarts, and he is ready to find the perfect active family. At about 80 lbs, he's equal parts energy and couch potato.❤️🌟Chance was saved from the Bradshaw shelter as a final plea dog—meaning he was running out of time! His foster parents (who saved him) say he is a GREAT dog, but they just adopted another dog and cannot keep him permanently. Now, this handsome boy is looking for a home to call his own!❤️🌟 Why you’ll love Chance:What's not to love?Smarty Pants: Trained in sit, stay, lie down, and touch hands. He recently attended a dog training class with Daack Pack trainers. Easy Keeper: Housebroken and crate-trained.Health Verified: Fully vaccinated, neutered, heartworm negative, and microchipped.Personality: Lovable lug. He loves playing with toys, running around, and napping.🏡 The Perfect Home: Chance would thrive in an active home that can take him on adventures but also appreciates a good couch snuggle. Although he's done just fine in the foster home with their senior couch potato female dog, he may do best as your one-and-only pet, or with a solid/social female. ❤️ He has done very well with kids 8 yrs and older. He might be too exuberant for the younger kiddos.🎥 VIDEO (with people when he was at shelter): https://youtube.com/shorts/yLRlEmp-D6c?feature=share🎥 VIDEO (play yard when he was at shelter) Note that Chance was intact at the time of this video. He has been neutered since April 2026.)https://www.youtube.com/watch?v=32kh0heQ7Cs📍 Located in Elk Grove, CA.📞 Contact his foster mom to learn more: 774-641-1955 or email SacCaninePlacementAssistance@gmail.com for an adoption application.Please share to help this final plea survivor find his happily ever after! 🐾❤️PS The box for "good with dogs?" you can only say yes or no. Like many dogs, Chance is on the spectrum, he's leash reactive on walks. He is fine with senior foster sister.

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Adam

Mastiff Mixed Breed (Medium)

Male, 2 yrs 4 mos

Oakland, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Spayed or Neutered,

Story

Adam is an 80-pound silly, calm and cuddly boy doing so well with his amazing\ foster who says her favorite qualities are his squishy, loveable face, his soft fur, and his smile. Adam walks well on leash and is eager to "sit" for his dinner. He gets along great with other dogs. He is calm, playful and has good manners and is not overly curious about cats. He is low energy but really enjoys going for walks and being let out to run and explore in a fenced area. Adam is protective of his family and property and, with proper introductions, is the most loyal and gentle guy! He needs an adopter who can guide him with boundaries and offer lots of socialization opportunities. Everyone who meets Adam falls in love with him! He's just waiting for the right one who's ready to provide him a stable and loving home. If that's you, please submit an application and a volunteer will be in touch! (HD)

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Vacaville, California.

Mastiff puppies and dogs in Vacaville, California

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Adopt a Mastiff near you in Vacaville, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Vacaville, California

These Mastiffs are available for adoption close to Vacaville, California.

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Mastiff puppies and dogs in Vacaville, California

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Adopt a Mastiff near you in Vacaville, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Vacaville, California

These Mastiffs are available for adoption close to Vacaville, California.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Vacaville, California

Mastiff shelters & rescues in Vacaville, California

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics