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Mastiff puppies and dogs in Vacaville, California

Looking for a Mastiff puppy or dog in Vacaville, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Vacaville, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Vacaville, California

These Mastiffs are available for adoption close to Vacaville, California.
We'll also keep you updated on ROXY's adoption status with email updates.
Photo of ROXY

ROXY

Mastiff

Female, 1 yr
Fairfield, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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We'll also keep you updated on ANGELICA's adoption status with email updates.
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Photo of ANGELICA

ANGELICA

Mastiff

Female, 2 yrs
Sacramento, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-
We'll also keep you updated on Creed's adoption status with email updates.
Photo of Creed

Creed

Mastiff

Male, Adult
Sacramento, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Creed was given to us at 10 weeks by a neighbor. It was a family decision to get a dog. Family is comprised of dad, mom, three daughters now ages, 7,10 and 13 with a new 2 month old newborn and a grandparent. Creed recieved some virtual training with a trainer during his first year, we were unable to complete that training due to cost. But he was taught to heel, sit, come, place, and go to his crate. He is playful, loves tug, fetch, run. Girls love him. Occasionally he does chew things that are not his.He loves to be active. I retired and started to travel, my son works and has a newborn. We do not feel we can give him the attention he needs anymore. We feel he needs to work and be busy.With the right home and a bit more training and company, he will thrive. Right now he is getting frustruated. He whines at night before going to sleep. In the morning, hes upset if we dont take him walking and barks. He barks at strangers.We are not doing him justice.
We'll also keep you updated on Adam's adoption status with email updates.
Photo of Adam

Adam

Mastiff Mixed Breed (Medium)

Male, 1 yr 9 mos
Oakland, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Adam is a 65-pound calm and cuddly boy who is doing well with his amazing foster. He now walks on a leash and is eager to "sit" for his dinner. He gets along great with female dogs and is not overly curious about cats. He is a protective boy over his family and property, but when given proper introductions, he is the most loyal and gentle guy you'll ever meet. He needs an adopter who can guide him with boundaries and offer lots of socialization opportunities.
We'll also keep you updated on She-Ra's adoption status with email updates.
Photo of She-Ra

She-Ra

Mastiff

Female, 7 yrs
Dublin, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered, Shots are up-to-date,
Story
Do you like BIG dogs? She-Ra may be your girl! She is a female Mastiff mix, who is approximately seven years old, and currently weighs 93 pounds. Despite her size, she is a lower-energy pup, who enjoys going for walks, but is mostly happy to hang out and just be by your side! She was brought to our shelter on 11/17/25 after being found in unincorporated Livermore. She hasn't been reclaimed by her previous person, so she's now looking for a new home! She has been vaccinated, spayed, and micro-chipped. She-Ra is dog-selective, which is common amongst adult dogs, and means that she may appreciate some dogs more than others. If you already have another dog at home, we'll ask you to bring them to meet her too, prior to adoption. Her adoption fee is $35, plus licensing (if applicable). Her spay surgery has been sponsored by our friends at the Tri-Valley Animal Rescue! She-Ra qualifies for Senior Sunday! Adopt her on a Sunday and we'll waive her adoption fee!
We'll also keep you updated on Apollo's adoption status with email updates.
Photo of Apollo

Apollo

Mastiff

Male, Young
Castro Valley, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with cats, House-trained, Shots are up-to-date,
Story
Meet our sweet boy Apollo 🐾 Apollo just turned 2 years old on January 5, 2026. He is a loving, affectionate pup who adores belly rubs and enjoys spending time with his people. Apollo is well-mannered and knows basic commands such as sit, stay, lay down, and shake paws. We are heartbroken to say that we are looking for a new family for Apollo due to circumstances beyond our control—our landlord has required that we rehome him. This decision has not been easy, and our only wish is to find a home that will love and care for him just as much as we do. If you are willing to give Apollo a chance and provide him with a safe, loving forever home, please reach out. He truly deserves a family who will cherish him.

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Vacaville, California.

Mastiff puppies and dogs in nearby cities

Related breeds in Vacaville, California

Mastiff shelters & rescues in Vacaville, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Vacaville, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

5.2 miles

Solano County Animal Care Services

2510 Clay Bank Rd., Fairfield, CA 94533

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

28.2 miles

Front Street Animal Shelter - City of Sacramento

2127 Front Street, Sacramento, CA 95818

Pet Types: cats, dogs, rabbits, small animals

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Rescue

40.3 miles

Rocket Dog Rescue

3561 Foothill Blvd, Oakland, CA 94601

Pet Types: dogs

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Shelter

41.9 miles

East County Animal Shelter

4595 Gleason Drive, Dublin, CA 94568

Pet Types: cats, birds, dogs, rabbits, small animals

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Shelter

43.4 miles

City of Stockton Animal Shelter

1575 S. LINCOLN ST, STOCKTON, CA 95206

Pet Types: cats, dogs, rabbits

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Rescue

43.6 miles

NorCal Bully Breed Rescue

Citrus Heights, CA 95610

Pet Types: dogs

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Rescue

43.9 miles

California Bully Rescue

Pleasanton, CA 94588

Pet Types: dogs

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Rescue

43.9 miles

Tri-Valley Animal Rescue

PO Box 11143, Pleasanton, CA 94588

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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