Mastiff Adoption in Clayton, CA: Mastiff Puppies for Sale in Clayton, CA

Adopt a Mastiff near you in Clayton, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Clayton, California

These Mastiffs are available for adoption close to Clayton, California.

Nova

Mastiff

Female, 2 yrs

Concord, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Nova is a cuddle bug who lives for her favorite person. She’s housetrained, walks great on leash, and is friendly with other dogs. Treats and squeaky toys are the way to her heart, and once she trusts you, she’ll want to be by your side constantly. Nova can get anxious when left alone at first, but she’s shown she can settle down and handle it once she adjusts. She knows “sit” and is still warming up to strangers, so a little patience goes a long way with her. Nova’s ideal home: A backyard, daily walks, and people who want a loyal companion by their side. She does fine as an only dog or with other dogs. Because she jumps when excited, she’s better suited for a home without young kids who could easily be knocked over. ##2665648##

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Apollo

Mastiff

Male, Young

Castro Valley, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,

Story

Meet our sweet boy Apollo 🐾 Apollo just turned 2 years old on January 5, 2026. He is a loving, affectionate pup who adores belly rubs and enjoys spending time with his people. Apollo is well-mannered and knows basic commands such as sit, stay, lay down, and shake paws. We are heartbroken to say that we are looking for a new family for Apollo due to circumstances beyond our control—our landlord has required that we rehome him. This decision has not been easy, and our only wish is to find a home that will love and care for him just as much as we do. If you are willing to give Apollo a chance and provide him with a safe, loving forever home, please reach out. He truly deserves a family who will cherish him.

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Cricket - ECAS

Mastiff Mixed Breed (Medium)

Female, 4 yrs

Pleasanton, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Spayed or Neutered,

Story

Cricket was brought to our shelter on 2/18/26 after being found in Castro Valley. She hasn't been reclaimed by her previous person, so she's now looking for a new home! Her adoption fee is $35, plus licensing (if applicable), plus the cost of her spay surgery. Cricket’s Shelter ID# is 88940. She is an approximately 4-year-old, black, Cane Corso mix. She currently weighs around 82 lbs. She has already been vaccinated, microchipped and spayed and is ready to go to her new home! Cricket is located in kennel A-1. ** Age shown is an estimate only ** THIS IS A COURTESY POSTING If you are interested, please call the East County Animal Shelter at 925-803-7040 to see if this dog is still available.

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Lila

Mastiff Mixed Breed (Large)

Female, 2 yrs

Pleasanton, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs,

Story

Let us introduce you to Lila, formerly Blue from Stanislaus Animal Services. Now she’s living her best life as a resident gentle giant and professional couch potato. This sweet girl is equal parts lover, snuggler, and breeze-catching car ride enthusiast. If you’ve got a couch and a car with windows that roll down halfway… congratulations, you already have two of Lila’s favorite things in life. 🚗💨 With new people, Lila is a polite little introvert. She might play it cool at first, but before long she’ll wander over for the classic “hello, may I sniff your hand and accept a gentle pat?” greeting once you pass her vibe check. She’s still very much a baby in a big dog body, so she’s learning things like crate training and impulse control. Lila truly wants to be good — sometimes her baby brain just gets a little louder than her manners. If she disagrees with being crated you might hear a dramatic protest that could easily earn her an Oscar nomination. Consistency and structure are helping her improve every day. This girl is smart and eager to learn. She’s been doing great with the cats in her foster home (who are basically dog-savvy professionals at this point). If one sprints, her “must chase fast thing” instinct may kick in, but a quick correction brings her right back to reality. Because of this, any home with small animals should plan for slow and thoughtful introductions. Lila is a mastiff mix, which means she’s a big girl with an even bigger heart who will thrive with a confident human to guide her. She can be a little unsure of herself at times, but with leadership and reassurance she settles in beautifully. 📍 Fostered in San Jose, CA

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Adam

Mastiff Mixed Breed (Medium)

Male, 1 yr 11 mos

Oakland, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Spayed or Neutered,

Story

Adam is an 80-pound silly, calm and cuddly boy doing so well with his amazing\ foster who says her favorite qualities are his squishy, loveable face, his soft fur, and his smile. Adam walks well on leash and is eager to "sit" for his dinner. He gets along great with other dogs. He is calm, playful and has good manners and is not overly curious about cats. He is low energy but really enjoys going for walks and being let out to run and explore in a fenced area. Adam is protective of his family and property and, with proper introductions, is the most loyal and gentle guy! He needs an adopter who can guide him with boundaries and offer lots of socialization opportunities. Everyone who meets Adam falls in love with him! He's just waiting for the right one who's ready to provide him a stable and loving home. If that's you, please submit an application and a volunteer will be in touch! (HD)

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Breathless Mahoney

Mastiff Mixed Breed (Medium)

Female, 2 yrs 6 mos

Oakland, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Breathless Mahoney is a gorgeous ~2 year-old mastiff mix. Mahoney currently weighs 90 lbs, but needs to gain some weight and will probably fill in at around 100-120 lbs. Breathless Mahoney is a little shy with new people but once she warms up, she loves to play and snuggle. She is very playful with other dogs and has a puppy-like rough-and-tumble play style. If you're interested in Breathless Mahoney, fill out a questionnaire today!

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Mastiff puppies and dogs in Clayton, California

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Mastiff puppies and dogs in Clayton, California

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Adopt a Mastiff near you in Clayton, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Clayton, California

These Mastiffs are available for adoption close to Clayton, California.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Clayton, California

Mastiff shelters & rescues in Clayton, California

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics