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Mastiff puppies and dogs in Mooresville, Indiana

Looking for a Mastiff puppy or dog in Mooresville, Indiana? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Mooresville, Indiana Other pups in Mooresville, Indiana Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Mooresville, Indiana Mastiff shelters and rescues in Mooresville, Indiana Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Mooresville, Indiana

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Mooresville, Indiana

These Mastiffs are available for adoption close to Mooresville, Indiana.
We'll also keep you updated on SUNSHINE's adoption status with email updates.
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SUNSHINE

Mastiff

Female, 2 yrs 2 mos
Indianapolis, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Sunshine lives up to her name—she’s a sweet, affectionate girl with a playful spirit and a gentle, slightly shy side. She can be a bit of a scaredy cat at first, but once she feels safe, her loving personality shines through. After just a few days out of the kennel, Sunshine has already begun to settle in, showing how much she benefits from a calm, stable environment. Sunshine is a high-energy dog who enjoys staying active. She does best with at least two walks a day along with backyard playtime to burn off energy and satisfy her curiosity. She’s smart and eager to learn, especially when treats are involved, and is currently working on cues like sit and stay. Positive reinforcement—praise, affection, and gentle guidance—has been especially effective for her. Affection is Sunshine’s love language. She always wants to be near her person, giving and receiving pets, and she has no known sensitivities to handling. Her paws were sore when she first arrived, but that has since resolved, and she’s comfortable being touched all over—especially when it comes to ear scratches, which are her absolute favorite. Sunshine has been calm and friendly around the people she’s encountered so far and hasn’t shown any concerning reactions. She’s curious about other animals, gently sniffing a neighbor’s dog and observing nearby chickens without chasing or showing aggression. She has not displayed any possessiveness over food or toys.Like many young or energetic dogs, Sunshine is still working on her manners. She sometimes jumps when excited and is learning leash skills, as she can pull on walks. She also has a playful habit of trying to steal items like shoes or glasses, but she’s beginning to understand what belongs to her and what doesn’t with consistent redirection. With continued structure, patience, and plenty of love, Sunshine has all the makings of a wonderful companion. She’s curious, intelligent, and deeply affectionate—and with more time outside the kennel in a stable home, she’s sure to keep blossoming into an amazing dog. Adoptions are free and include support from our adoption team to ensure a smooth transition from the shelter to your home. Adopted pets are vaccinated, microchipped, and spayed/neutered before leaving with you. To view our current available animals, please visit: https://indy.gov/activity/adopt-a-pet.

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We'll also keep you updated on CLYDE's adoption status with email updates.
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CLYDE

Mastiff

Male, 8 yrs
Indianapolis, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-

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We'll also keep you updated on BLACK JACK's adoption status with email updates.
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BLACK JACK

Mastiff

Male, 10 yrs
Indianapolis, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-

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We'll also keep you updated on Smoke's adoption status with email updates.
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Smoke

Mastiff

Male, 3 yrs 6 mos
Avon, IN
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Smoke, a striking extra-large Grey Merle Mastiff-Mix, has faced significant challenges throughout his three years of life. After being surrendered to a shelter in 2023, he was fortunate enough to be rescued by a compassionate local foster just days before a scheduled euthanasia. Smoke was later adopted, but due to unfortunate circumstances, his family had to return him to the shelter. He is now with Misty Eyes and is seeking a second chance at a loving forever home. Smoke is not only a good boy, but also gets along well with other dogs and enjoys people, making him a wonderful companion. We warmly invite anyone interested in giving Smoke the loving home he deserves to submit an adoption application through our website at https://www.mistyeyes.org/adoptionapplication.

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We'll also keep you updated on Atlas's adoption status with email updates.
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Atlas

Mastiff Labrador Retriever

Male, 5 yrs 5 mos
Indianapolis, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Atlas, the gentle giant!This 60-pound, 5 year old, brindle mastiff and lab mix is a sweet boy who's been waiting for his forever home for far too long. He's ready to bring joy and love into your life!Atlas has a soft spot for women and is a total ladies' man (but he'll tolerate the guys too. He's a playful and happy boy who loves nothing more than frolicking in the yard with his favorite toys or snuggling up with his favorite people. And, oh, those adorable crossed paws? The epitome of sophistication!We're looking for a special home for Atlas, one with no young children (they can be a bit too loud for his taste). He's not fond of dogs or cats either, so a solo pet situation would be best. But don't worry, he'll keep you entertained with his playful antics and affectionate nature!Atlas is potty trained, crate trained (no accidents in the home or crate while we're away), and a great walker on the leash.If you're ready to add a lovable, laid-back companion to your life, adopt Atlas today! ##1759977##

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We'll also keep you updated on TIGER - SOS RESCUE's adoption status with email updates.
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TIGER - SOS RESCUE

English Mastiff

Male
Morgantown, IN
Size
(when grown) -
Details
Spayed or Neutered,
Story
TIGER! Mastiff mix, 14 months old, brindle Contact:  savingoutstandingsouls@gmail.com  October 14, 2025, 10:06 pm

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These pups are in Mooresville, Indiana too!

Below are our newest added Mastiffs available for adoption in Mooresville, Indiana. To see more adoptable Mastiffs in Mooresville, Indiana, use the search tool below to enter specific criteria!
We'll also keep you updated on Fresca's adoption status with email updates.
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Fresca

St. Bernard

Female, 1 yr 9 mos
Mooresville, IN
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Fresca is waiting for you ❤ This beautiful 1 and a half year old St. Bernard mix is full of spunk, personality, and smarts. Her young age and working breed genes means she's a busy girl, always looking for something to do. Give her a job or task and she's on it! She's smart as a whip and a super fast learner. She has been working hard on her training and manners. 🐾 Does well in crate or kennel. 🐾 75lbs of fluffy softness 🐾 Good in the car 🐾 Will do best as an only pet 🐾 Food/treat motivated 🐾 Experience with this breed is a plus 🐾 Loves enrichment toys and her Nylabones Fresca is more than ready to experience a home and family of her very own where she can continue to learn and grow. She can be fostered or adopted. Adopt 👇 https://www.shelterluv.com/matchme/adopt/FLR/dog Foster application 👇 we provide everything for you https://www.shelterluv.com/matchme/foster/4LR/dog

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Mooresville, Indiana.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Mooresville, Indiana

Bullmastiffs in Mooresville, Indiana Neapolitan Mastiffs in Mooresville, Indiana Saint Bernards in Mooresville, Indiana

Mastiff shelters & rescues in Mooresville, Indiana

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Mooresville, Indiana. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

10.6 miles

Indianapolis Animal Care Services

2600 S Harding St, Indianapolis, IN 46221

Pet Types: cats, dogs

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Rescue

14.1 miles

Misty Eyes Animal Center

616 South CR 800E, Avon, IN 46123

Pet Types: cats, dogs

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Rescue

14.4 miles

Lucci's House Bully Rescue

Indianapolis, IN 46227

Pet Types: dogs

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Rescue

15.8 miles

LUV A DOG Rescues and Adoptions

Morgantown, IN 46160

Pet Types: cats, dogs

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Rescue

16.3 miles

Sketchy Mutts and Underdogs

Indianapolis, IN 46222

Pet Types: dogs

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Rescue

16.3 miles

S.O.A.R. Initiative, Inc.

4025 W 10th St, Indianapolis, IN 46222

Pet Types: cats, dogs

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Rescue

17.2 miles

Animal House Sanctuary

185 W 416 S, Indianapolis, IN 46204

Pet Types: cats, birds, dogs, farm animals, rabbits, small animals

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Shelter

22.6 miles

IndyHumane

7929 N. Michigan Rd, Indianapolis, IN 46268

Pet Types: cats, dogs

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Rescue

28.8 miles

Saving Outstanding Souls

Indianapolis, IN 46236

Pet Types: cats, dogs

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Rescue

33.4 miles

Our Lil' Bit of Heaven Animal Rescue and Sanctuary

Poland, IN 47868

Pet Types: dogs, farm animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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