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Great Dane puppies and dogs in National City, California

Looking for a Great Dane puppy or dog in National City, California? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in National City, California

We don't see any Great Danes available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Great Danes in cities near National City, California

These Great Danes are available for adoption close to National City, California.
We'll also keep you updated on Moo 2's adoption status with email updates.
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Moo 2

Great Dane

Male, Adult
San Diego, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered,
Story
Age: 3 years old Gender: Male Breed: Great Dane mix Weight: 109 lbs Personality: Moo is the sweetest boy and will bring joy to any home he goes to. He has the heart and love to match his size! Education: Potty trained, does not require a crate. Working on getting a little better with leash training. Favorite Activities: Walks, running around in the yard, being with his family and other pets Looking for: He would thrive with another dog in the home with a proper intro. Adoption Fee: $ 500 ##2280914##
We'll also keep you updated on Paige's adoption status with email updates.
Photo of Paige

Paige

Great Dane American Pit Bull Terrier

Female, Adult
San Diego, CA
Size
(when grown) -
Details
Not good with kids, Not good with dogs, Not good with cats, Spayed or Neutered,
Story
How this pet arrived: Paige was brought in by our Humane Law Enforcement team. At SDHS:Paige has been vaccinated, microchipped and is spayed. She is now ready for her new home! Why this pet is the one for you:Meet Paige! A sweet gal that is looking for a nice cozy home to settle into. Paige may start off a little bit shy when meeting new humans, but that nervousness burns off rather quickly and she transforms into such a sweet heart! She is truly a gentle giant that can't wait to give you as much love as you give her. We may not know much about her years before she entered our care, but we are so confident that she is going to have a bright future! Paige has some medical challenges that may require ongoing care once she goes to her new home. Our Adoptions and Medical teams will be happy to go over what that care may look like with you before adoption. How can you resist that precious face? Stop by our San Diego Campus and ask about Paige today! Primary Color: White Secondary Color: Black Weight: 86.3125 Age: 6yrs 4mths 2wks
We'll also keep you updated on Andromeda's adoption status with email updates.
Photo of Andromeda

Andromeda

Great Dane

Female, Adult
El Cajon, CA
Size
(when grown) -
Details
Not good with kids, Not good with dogs, Not good with cats, Spayed or Neutered,
Story
How this pet arrived: This pet was brought in by our Humane Law Enforcement team on April 30, 2025. Why this pet is the one for you:Andromeda is a 5-year-old female Great Dane who embodies the gentle giant spirit. She's calm, affectionate, and incredibly loving. While she does have some medical issues, our adoption team will happily discuss everything in detail to ensure you're fully informed. Andromeda also has some restraint sensitivity, so she'll need a patient family who can respect her boundaries. Despite her size, she's as sweet and gentle as they come and will make a loyal companion for the right home. At SDHS:This pet has been vaccinated, microchipped and spayed/neutered. This pet is now ready for their new home! Primary Color: White Secondary Color: Black Weight: 102 Age: 5yrs 6mths 1wks
We'll also keep you updated on Valentino's adoption status with email updates.
Photo of Valentino

Valentino

Great Dane

Male, Young
El Cajon, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, Shots are up-to-date,
Story
Valentino came to my life a year ago, his a healthy and playful dog he loves to be loved his a good company dog. My two daughters play with him we like taking him to the beach almost every weekend. We want someone to adopt him someone that takes good care of him, has time to walk him, we are worried about Valentino. We hope that his new owner loves him like we do or more we agree Valentino deserves a better life. Unfortunately the renter were we live doesn’t no longer have Valentino.
We'll also keep you updated on Odin's adoption status with email updates.
Photo of Odin

Odin

Great Dane

Male, Puppy
El Cajon, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Oden is a wonderful and growing Great Dane puppy. He spent the first five months of his life on a 5 to 6 foot chain. So when he arrived at the shelter, he did not have a lot of manners. But he is sweet as all get out. He is loving, playful, and just wonderful!
We'll also keep you updated on Odin's adoption status with email updates.
Photo of Odin

Odin

Great Dane

Male, 2 yrs 4 mos
El Cajon, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Oden is a wonderful and growing Great Dane puppy. He spent the first five months of his life on a 5 to 6 foot chain. So when he arrived at the shelter, he did not have a lot of manners. But he is sweet as all get out. He is loving, playful, and just wonderful! **** Please read adoption information carefully!!!**** Odin is a stunningly handsome little boy -male, 7 months -supposedly pure-bread, -Neutered -Current Weight : 90 lbs, will grow -Crate trained -Potty trained Odin is a big, funny bundle of joy, energy, and affection. He is just a big goofball! Odin is still a puppy, and will continue to grow. He is on the bigger side, but has an abundance of affection and cuteness! Odin is a well-adjusted puppy who has been hand raised. He has never shown any signs of aggression of any kind, including food aggression, although he can occasionally be a little rambunctious. He really thinks that he is a little dog…. ? Odin wants to be a lapdog; he can’t quite figure out why he doesn’t fit in my lap, but he settles for putting his head in my lap, since the rest of him doesn’t fit 😜 Odin is used to playing and sleeping with the other dogs on the property. He is well socialized, both with humans and dogs. While I have never seen him interact with a cat, I have no reason to anticipate a problem. ************************************ ADOPTION INFORMATION ************************************ I only adopt LOCALLY; San Diego and immediate vicinity. No long distance. Certainly no out of state. I cannot respond to questions as to whether the animal is available. Please DO NOT contact me asking if the animal is available. If the dog is listed as adoptable, it is available. A home check and a background check are MANDATORY to be considered. If you are unable or unwilling to consent to these requirements, please do not apply. An adoption interview Is REQUIRED. One of our volunteers must meet and observe the dog interact with every member of the household, including pets. Preference will be given to individuals who follow the instructions AND provide complete information for adoption purposes. 1) Please go to our website ( http://aaofus.org/adoption-application.html ) 2) submit it online. Must include dog’s name and “forward to Kim” under pet’s name 3) then forward the confirmation email to me directly at animalsandkim@gmail.com That’s it: easy Peezy! You must Submit an application or at least provide written answers to the following questions in an email in order for me to respond: Must include information on EVERY person in household Number of people in household and their ages ______________________________ ____________________________________________________________ occupations ________________________________________________________________________________________ Type of residential dwelling? __________________ Rent or own? Address: __________________ __________________ __________________ Phone number: __________________ Text available? does anyone in the family suffer from allergies? ___________________ I currently own _____ dogs and _____ cats _____ other animals (please specify) their breed(s) and age(s) are as follows: ____________________________________________________________ are you willing to housebreak this pet? ________________ how will you exercise your pet ______________________ how long will your pet be left alone during the day or night _______________ where will your pet sleep ___________________________________________ do you have a door that will enable your pet to go in and out of the house freely while he is being house trained? do you have a swimming pool ?________________________________ dogs frequently dig, chew and bark - are you willing to work with the dog to stop this behavior? under what circumstance would you not be able to keep your dog? Pets can live 12 to 15 years. Would anyone be willing to help with your pet if you could no longer take care of him/her?

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Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in National City, California.

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Great Dane shelters & rescues in National City, California

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in National City, California. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

6.4 miles

The Animal Pad - CA Chapter

San Diego, CA 92103

Pet Types: dogs

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Shelter

8.4 miles

San Diego Humane Society - San Diego Campus

5500 Gaines Street, San Diego, CA 92110

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

11 miles

San Diego Humane Society - El Cajon Campus

1373 N. Marshall Ave., El Cajon, CA 92020

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

13.8 miles

Animal Advocates of the US - San Diego Chapter

El Cajon, CA 92122

Pet Types: cats, dogs, rabbits

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Rescue

27.5 miles

Frosted Faces Foundation

1448 Pine St, Ramona, CA 92065

Pet Types: cats, dogs

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Rescue

31.8 miles

K9 Connection Pet Re Homing and Adoption

Escondido, CA 92027

Pet Types: dogs

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Rescue

31.8 miles

TLC K9 Rescue

Escondido, CA 92027

Pet Types: dogs

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Rescue

35 miles

Amazing Dogs

Carlsbad, CA 92011

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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