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Great Dane puppies and dogs in Lancaster, Pennsylvania

Looking for a Great Dane puppy or dog in Lancaster, Pennsylvania? Adopt a Pet can help you find an adorable Great Dane near you.

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Adopt a Great Dane near you in Lancaster, Pennsylvania

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Or, how about these Great Danes in cities near Lancaster, Pennsylvania

These Great Danes are available for adoption close to Lancaster, Pennsylvania.
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Bruce

Great Dane American Pit Bull Terrier

Male, Adult
Marietta, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Can’t be off leash or he will run away. If you have a fenced in yard he will run around it all day
Photo of Maeve

Maeve

Great Dane

Female, 3 yrs 5 mos
Sinking Spring, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Spayed or Neutered,
Story
Meet Maeve 💜 Maeve is a beautiful 3-year-old Great Dane with the sweetest soul and the kind of face you instantly fall in love with. She came to rescue after spending time in a commercial breeding situation and is now learning what it means to simply be loved, spoiled, and part of a family. She is affectionate, goofy, gentle, and incredibly people-oriented. Maeve loves being near her humans, whether she’s exploring the backyard, going for walks, or curling up beside you on the couch for snuggles. She truly just wants to be included in everyday life and close to her people. Maeve rides very nicely in the car and settles in well, especially if she has a cozy blanket nearby. She recently went to the groomer and did great for both bath time and nail trims. While she can be a little nervous with new experiences at first, she responds beautifully to patience, reassurance, and kindness. Maeve is housebroken, well-mannered in the home, and ready to find a family of her very own. Because she would do best as the center of attention, she is looking for a home with no other dogs where she can feel safe, secure, and fully loved. Maeve is spayed, gastropexied (stomach tacked), microchipped, and up to date on vaccines. She is currently being fostered in York Haven, Pennsylvania. If you’re looking for a loyal best friend with a huge heart and so much love to give, Maeve may just be your perfect girl. Kennel license 9117 PO box 2372 Reading pa 19608
Photo of Celeste

Celeste

Great Dane Catahoula Leopard Dog

Female, Adult
Harrisburg, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
PLEASE NOTE! Unless stated otherwise, our dogs and puppies are located in Arkansas, and transported to the north/northeast once adopted. We do occasionally have dogs/puppies placed in foster homes in the north/northeast. In the cases where the pet is somewhere other than Arkansas, it will be noted beside the name of the pet.       6/23 Still available.  Celeste.   This girl had waited too long and us holding up a spot for others in need. Please share! She is all the things. A stunning beauty, heartwarmingly affectionate, and playfully mischievous in the most innocent way. She follows some basic commands such as “sit”, is house trained, and very food motivated. We believe her to be a Great Dane mix, with possibly a dash of Mastiff thrown in there. Maybe some Catahoula? We don’t know for sure. At about 80 lbs and just over a year old, she could still grow some. She is spayed, vaccinated, microchipped, and is current on flea/tick/heartworm prevention. Located in Arkansas. She can be adopted locally, but transport is available to the New England area as well. Adopter must be able to pick up or arrange for someone to pick up for them in PA, NY, or CT on Saturdays. To apply, please fill out the adoption app: https://form.jotform.com/212690945239059  email: apps.aasr@gmail.com with any questions. Visit this organization's web site to see any additional information available about this pet.Our typical adoption fee for puppies younger than 6 months old is $400, and for older puppies and adults, the usual fee is $350. This includes microchip, spay/neuter,  up to date on age appropriate vaccinations, dewormings, flea/tick treatment, and heartworm test (if over 6 months old) as well as heartworm treatment if they test positive. There is a transport fee of $150 per dog, depending on the transporter. We use Pack Leaders Rescue Dog Transport most often, but also use Hearts Transport as well on occasion. Please visit our Facebook page too! https://www.facebook.com/adoptastrayrescueorg For more info regarding adopting, email apps.aasr@gmail.com Thank you for considering one of our rescue babies!June 26, 2026, 9:29 am
Photo of Pluto

Pluto

Great Dane Great Pyrenees

Male, Puppy
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   June 24, 2026, 2:11 pm
Photo of Robin

Robin

Great Dane Great Pyrenees

Male, Puppy
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   June 24, 2026, 2:11 pm
Photo of Mickey

Mickey

Great Dane Great Pyrenees

Male, Puppy
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   June 24, 2026, 2:11 pm

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Great Dane shelters & rescues in Lancaster, Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Lancaster, Pennsylvania. Browse these Great Dane rescues and shelters below.

Here are a few organizations closest to you:

Rescue

23.7 miles

Zoe's House Rescue

P.O Box 2372, Sinking Spring, PA 19608

Pet Types: dogs

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Rescue

29.8 miles

Adopt A Stray - PA transport

Harrisburg, PA 17105

Pet Types: dogs

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Rescue

29.8 miles

Mastiffs To Mutts - Central PA

Harrisburg, PA 17109

Pet Types: dogs

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Rescue

35.9 miles

Mastiffs to Mutts - Eastern PA

Exton, PA 19341

Pet Types: dogs

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Rescue

41.2 miles

All 4 Paws Rescue

Malvern, PA 19355

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

47.8 miles

Reach Out Rescue & Resources

P. O. Box 542, Westminster, MD 21158

Pet Types: cats, dogs

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Rescue

48.2 miles

Hinde's Animal Rescue Team

65 S Pennell Road, Media, PA 19063

Pet Types: cats, dogs, farm animals, rabbits, small animals

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Want to learn more about adopting a Great Dane puppy or dog?

We've got all the info you need on adopting and caring for a Great Dane puppy. Check out the links below for everything you ever wanted to know about Great Dane puppies and adults.

Great Dane basics

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Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

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