Great Pyrenees Adoption in South Carolina: Great Pyrenees Puppies for Sale in South Carolina

Adopt a Great Pyrenees near you in South Carolina

Below are our newest added Great Pyrenees available for adoption in South Carolina. To see more adoptable Great Pyrenees in South Carolina, use the search tool below to enter specific criteria!

milly

Great Pyrenees

Female, 4 yrs

EFFINGHAM, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, House-trained,

Story

PLEASE NOTEA pre-adoption form must be completed in person at the shelter.If the animal is already spayed or neutered, they can be adopted and go home the same day. This will be clearly noted in their description.Once your pre-adoption process is complete, we will schedule a spay/neuter appointment, typically within 10 days. You will be able to bring your new pet home once the procedure has been completed.At this time, all adoption fees are being waived.If you have any questions about your application, please contact the Florence County Animal Shelter directly at 843-665-3053.

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lulu

Great Pyrenees

Female, 8 yrs

EFFINGHAM, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

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Artic

Great Pyrenees/Mixed Breed (Large)

Female, 4 yrs

Myrtle Beach, SC

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained,

Story

This dog's bio is coming soon! All adoptions begin with an application:https://linktr.ee/aaart1082 Adoption fees include age appropriate vaccines, microchip, deworming, and spay/neuter (scheduled if too young.). While we do adopt out of state, all of our dogs are in foster homes in the Myrtle Beach area. We require in person meet and greets and do not provide transport.

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Luna

Great Pyrenees

Female, Young

Bradley, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Needs experienced adopter,

Story

Update I originally had they were 11 years old. That was a mistake!!!! I rescued this dog a year ago. She is approximately 2 years old. She is very sweet. She has a sister as well. We love them but they are too much for us to handle. They like to roam and I constantly have to go find them. I have to keep them locked up all the time which is not fair at all. They need land to roam which I dont have. I have tried for over a year but it is not working out. They are very loving dogs. Love everybody. The other ones name is Star. I just had surgery and are not able to go find them all the time. They would be great for a farm. Please help me!

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Thoreo

Great Pyrenees

Male, Young

Lexington, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs,

Story

✨ STILL AVAILABLE! ✨ Meet the handsome Thoreo (Thor + Oreo) 🐾 — a gentle, goofy boy still searching for his forever home! If you can’t adopt, please share to help him find his people ❤️ 📍 Location: Lexington, SC 🐾 Name: Thoreo 🎂 Age: ~1 year 🐕 Breed: Great Pyrenees – currently 65 lbs (he came to us severely underweight, which may have slightly stunted his growth). Appears purebred — double rear dewclaws ✅, GP-standard coat and eye color — though not DNA-confirmed. ♂️ Sex: Male 💉 Vetting: Neutered, microchipped, up to date on rabies, DHLPP, and Bordetella; heartworm negative; current on flea & heartworm prevention; and dewormed. 👧🐶🐱 Good with: Dogs, cats, and kids — friendly with everyone but still has puppy energy, so supervision is best with very young children. He has not been tested around chickens or other livestock. ⚕️ Aggression or medical issues?: None 💖 He can come off intimidating at first because he’s a loud talker and will bark when meeting new animals — classic Pyrenees alerting behavior! But he’s never been reactive or aggressive. He was fully tested with a dominant alpha male who quickly had him submitting calmly, and there were no issues afterward. 🏡 House/crate trained?: Fully house trained. He’s never needed a crate — enjoys outdoor time in true Pyrenees fashion when unsupervised. 💛 Personality: Thoreo is an affectionate, well-mannered boy who loves people and attention. He’ll sit politely for brushing (his favorite activity — except his tail ✂️) and is very food-motivated… just not a fan of veggies 🥦🚫. Walks nicely on leash with only gentle pulls here and there. He was raised as a pet, not a livestock guardian, so he doesn’t show strong “working” instincts yet — but that could develop as he matures. He loves dog friends and would thrive in a home with another playful companion. 🌟 A secure fenced yard is required for his safety and happiness — Pyrenees love to explore! 📩 Message or comment if interested! Please include Thoreo’s name in your message, as I’m assisting with multiple rescues. 📝 Adoption application & contract required to ensure a loving, responsible home.

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Sanford

Great Pyrenees/Labrador Retriever

Male, Young

Ft Mill, SC

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with cats, House-trained,

Story

Sanford is a very sweet Great Pyrenese/Lab mix. We love Sanford, but due to allergies we cannot keep him. We are desperate to find a loving home for him. Will provide a large crate and 4 bags of food for him to help get him settled.

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Great Pyrenees puppies and dogs in South Carolina

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Adopt a Great Pyrenees near you in South Carolina

Below are our newest added Great Pyrenees available for adoption in South Carolina. To see more adoptable Great Pyrenees in South Carolina, use the search tool below to enter specific criteria!

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Great Pyrenees puppies and dogs in South Carolina

Jump to:

Adopt a Great Pyrenees near you in South Carolina

Below are our newest added Great Pyrenees available for adoption in South Carolina. To see more adoptable Great Pyrenees in South Carolina, use the search tool below to enter specific criteria!

Search for a Great Pyrenees puppy or dog

Great Pyrenees puppies and dogs in South Carolina cities

Great Pyrenees shelters & rescues in South Carolina

Looking for a specific shelter or rescue?

Want to learn more about adopting a Great Pyrenees puppy or dog ?

Great Pyrenees information

Great Pyrenees basics