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Mastiff puppies and dogs in North Carolina

Looking for a Mastiff puppy or dog in North Carolina? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff in North Carolina Search for a Mastiff puppy or dog Mastiff puppies and dogs in North Carolina cities Mastiff shelters and rescues in North Carolina Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in North Carolina

Below are our newest added Mastiffs available for adoption in North Carolina. To see more adoptable Mastiffs in North Carolina, use the search tool below to enter specific criteria!
We'll also keep you updated on BUTTERCUP's adoption status with email updates.
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BUTTERCUP

Mastiff

Female, 2 yrs 7 mos
Chapel Hill, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Hello! I was transferred to OCAS from another shelter and I am ready to find my family! I`m friendly, energetic, and ready to impress my people.

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We'll also keep you updated on MEGAN's adoption status with email updates.
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MEGAN

Mastiff

Female, 5 yrs 10 mos
Chapel Hill, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
I was transferred to OCAS from another shelter. I`m a sweet gal and I have done well with staff handling me at the shelter. I can be a dog selective, meaning I do well with some dogs but not with others. Like all newly adopted pets, I will need slow, monitored introductions to new people or pets in a home. Visit this page for more information about properly introducing pets.Please consider adopting me, I`m a great dog!

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We'll also keep you updated on Holly's adoption status with email updates.
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Holly

Mastiff/Mixed Breed (Medium)

Female, 5 yrs
Concord, NC
Size
(when grown) -
Details
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Story
🎄🐾 Meet Holly! 🐾🎄 If you’re hoping to add some extra holiday cheer to your home, look no further—Holly is ready to brighten your world! This gorgeous Mastiff mix is a bundle of joy, playfulness, and pure sweetness. Holly loves to explore, whether she’s sniffing around on a walk, checking out new sights, or bouncing her way into the next fun adventure. She’s a playful girl with a big heart, always ready to make a new friend or share a few tail wags. Despite her size, Holly is a total sweetheart who will happily lean in for attention and soak up all the love she can get. She’d make a wonderful companion for a family who enjoys playtime, snuggles, and outdoor adventures. If you’re ready to add a little holly-jolly magic to your life, come meet this festive girl today! ❤️🎅🌟

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We'll also keep you updated on 59893082's adoption status with email updates.
No photo available for 59893082

59893082

Mastiff

Male, 4 yrs
Greenville, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
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We'll also keep you updated on Louie's adoption status with email updates.
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Louie

Mastiff

Male
Rocky Mount, NC
Size
(when grown) -
Details
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Story
You can fill out an adoption application online on our official website.Visit this organization's web site to see any additional information available about this pet.If you are interested in meeting and possibly adopting this fabulous pet, please fill out the online adoption application at http://foranimals2002.com PLEASE NOTE: we do not have a shelter where you can come to view our available dogs. All of our dogs are in foster homes. You must complete an application and references will be checked by an Adoption Screener before you can meet the dog. December 3, 2025, 6:43 pm

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We'll also keep you updated on Josie's adoption status with email updates.
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Josie

Mastiff

Female
Rocky Mount, NC
Size
(when grown) -
Details
-
Story
You can fill out an adoption application online on our official website.Visit this organization's web site to see any additional information available about this pet.If you are interested in meeting and possibly adopting this fabulous pet, please fill out the online adoption application at http://foranimals2002.com PLEASE NOTE: we do not have a shelter where you can come to view our available dogs. All of our dogs are in foster homes. You must complete an application and references will be checked by an Adoption Screener before you can meet the dog. December 3, 2025, 6:43 pm

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in North Carolina.

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Mastiff puppies and dogs in North Carolina cities

Mastiff Puppies near me Mastiff in Aberdeen Mastiff in Albemarle Mastiff in Angier Mastiff in Apex Mastiff in Archdale Mastiff in Asheboro Mastiff in Asheville Mastiff in Ayden Mastiff in Belmont Mastiff in Bessemer City Mastiff in Black Mountain Mastiff in Boiling Spring Lakes Mastiff in Boone Mastiff in Brevard Mastiff in Burlington Mastiff in Butner Mastiff in Carolina Beach Mastiff in Carrboro Mastiff in Cary Mastiff in Chapel Hill Mastiff in Charlotte Mastiff in Cherryville Mastiff in Clayton Mastiff in Clemmons Mastiff in Clinton Mastiff in Concord Mastiff in Conover Mastiff in Cornelius Mastiff in Davidson Mastiff in Dunn Mastiff in Durham Mastiff in Eden Mastiff in Edenton Mastiff in Elizabeth City Mastiff in Elon Mastiff in Erwin Mastiff in Fairview Mastiff in Farmville Mastiff in Fayetteville Mastiff in Fletcher Mastiff in Forest City Mastiff in Fuquay Varina Mastiff in Garner Mastiff in Gastonia Mastiff in Gibsonville Mastiff in Goldsboro Mastiff in Graham Mastiff in Granite Falls Mastiff in Greensboro Mastiff in Greenville Mastiff in Hamlet Mastiff in Harrisburg Mastiff in Havelock Mastiff in Henderson Mastiff in Hendersonville Mastiff in Hickory Mastiff in High Point Mastiff in Hillsborough Mastiff in Holly Springs Mastiff in Hope Mills Mastiff in Huntersville Mastiff in Indian Trail Mastiff in Jacksonville Mastiff in Kannapolis Mastiff in Kernersville Mastiff in Kill Devil Hills Mastiff in King Mastiff in Kings Mountain Mastiff in Kinston Mastiff in Knightdale Mastiff in Laurinburg Mastiff in Leland Mastiff in Lenoir Mastiff in Lewisville Mastiff in Lexington Mastiff in Lincolnton Mastiff in Lumberton Mastiff in Maggie Valley Mastiff in Marion Mastiff in Matthews Mastiff in Mebane Mastiff in Mills River Mastiff in Mint Hill Mastiff in Mocksville Mastiff in Monroe Mastiff in Mooresville Mastiff in Morehead City Mastiff in Morganton Mastiff in Morrisville Mastiff in Mount Airy Mastiff in Mount Holly Mastiff in Mount Olive Mastiff in Nashville Mastiff in New Bern Mastiff in Newport Mastiff in Newton Mastiff in Oak Island Mastiff in Oak Ridge Mastiff in Oxford Mastiff in Pinehurst Mastiff in Pineville Mastiff in Pleasant Garden Mastiff in Raleigh Mastiff in Reidsville Mastiff in Roanoke Rapids Mastiff in Rockingham Mastiff in Rocky Mount Mastiff in Roxboro Mastiff in Salisbury Mastiff in Sanford Mastiff in Sawmills Mastiff in Selma Mastiff in Shelby Mastiff in Siler City Mastiff in Smithfield Mastiff in Southern Pines Mastiff in Spring Lake Mastiff in Stallings Mastiff in Statesville Mastiff in Summerfield Mastiff in Tarboro Mastiff in Thomasville Mastiff in Trinity Mastiff in Unionville Mastiff in Valdese Mastiff in Wadesboro Mastiff in Wake Forest Mastiff in Walkertown Mastiff in Washington Mastiff in Waynesville Mastiff in Weddington Mastiff in Wendell Mastiff in Whiteville Mastiff in Williamston Mastiff in Wilmington Mastiff in Wilson Mastiff in Winston Salem Mastiff in Winterville Mastiff in Woodfin Mastiff in Zebulon

Mastiff shelters & rescues in North Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in North Carolina. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Shelter

Pitt County Animal Services

4550 County Home Road, Greenville , NC 27858

Pet Types: cats, dogs

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Rescue

Friends of Rocky Mount Animals

P.O. Box 8766, Rocky Mount , NC 27804

Pet Types: dogs

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Rescue

Carolina Animal Network

Wendell , NC 27591

Pet Types: cats, dogs

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Shelter

Wake County Animal Center

820 Beacon Lake Drive, Raleigh , NC 27610

Pet Types: cats, birds, dogs, rabbits, small animals

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Shelter

Orange County Animal Services

1601 Eubanks Road, Chapel Hill , NC 27516

Pet Types: cats, dogs, rabbits, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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