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Mastiff puppies and dogs in North Carolina

Looking for a Mastiff puppy or dog in North Carolina? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff in North Carolina Search for a Mastiff puppy or dog Mastiff puppies and dogs in North Carolina cities Mastiff shelters and rescues in North Carolina Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in North Carolina

Below are our newest added Mastiffs available for adoption in North Carolina. To see more adoptable Mastiffs in North Carolina, use the search tool below to enter specific criteria!
We'll also keep you updated on Kevin's adoption status with email updates.
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Kevin

Mastiff

Male, Young
Shawboro, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Good with cats, Needs experienced adopter, House-trained,
Story
Kevin is a 2 year old Mastiff Mix who was rescued from an animal care center in Virginia. He is house trained, but when left alone he does tend to forget his manners and will have accidents in the house. We believe these accidents are caused by separation anxiety. Kevin does GREAT in the car and will happily accompany you on short drives or long trips. His ideal day would involve chasing tennis balls outside and then snuggling on the couch, as close to you as possible, for hours. Currently, Kevin lives with another dog and a cat. He does okay with both, but in his ideal home he would be an only pet. He has been around children and had no issues, but ideally his new home would not have kids. In his future home, Kevin would benefit from an owner (or owners) who can spend a lot of time with him and are experienced with his breed, his temperament, and some behavioral concerns.

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We'll also keep you updated on Eeyore's adoption status with email updates.
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Eeyore

Mastiff/Rhodesian Ridgeback

Male, 7 mos
Jacksonville, NC
Size
(when grown) -
Details
Good with kids, Good with dogs,
Story
Meet Eeyore! 🐾 Eeyore is a sweet Mastiff mix who’s still very much in the puppy stage and full of potential. This loyal boy forms deep bonds with those he trusts and will be your devoted companion through thick and thin. Eeyore is a little unsure at first—he can be nervous in new situations—but with patience, love, and gentle guidance, his confident, loving personality shines through. He’s still learning how to navigate the world on a leash, so he’ll need a patient hand and consistent guidance to help him feel secure during walks. If you’re looking for a loyal, velcro-style dog who will stick by your side once he warms up, Scooby is your guy. With a calm and understanding home, this sweet pup will flourish into the best companion you could ask for.

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We'll also keep you updated on Fritter Edgecombe's adoption status with email updates.
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Fritter Edgecombe

Mastiff/Mixed Breed (Large)

Male, 2 mos
Apex, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs,
Story
Meet your new best friend! 🐾 This sweet boy is a total people-lover—if you say hello, he’s already on his way over with a wagging tail and a heart full of excitement. He absolutely adores giving kisses and will happily entertain himself chasing ice cubes around like they’re the greatest treasure on earth. He’s got a playful, curious spirit and isn’t fazed by much—balloons and even the vacuum are just part of the fun in his world! He loves kids, shows wonderful respect for older dogs, and brings a gentle, happy energy wherever he goes. Mealtime is a breeze with this smart pup. He eats like a champ and already knows to sit patiently while waiting for his food. He’s also doing amazing with potty training, sleeps soundly through the night, and keeps his crate nice and dry. When he’s not playing, you’ll find him soaking up the sunshine—sunbathing is one of his absolute favorite pastimes. And when it’s time to wind down, he’s an expert snuggler who will happily curl up and keep you company. With his big personality and even bigger heart, he’s ready to leave a paw-sized imprint on yours. 💛

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We'll also keep you updated on Xena's adoption status with email updates.
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Xena

Mastiff

Female, 8 yrs 6 mos
WILSON, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs,
Story
Hi my name is Xena, a sweet 6 year old that was found roaming US 264A E. I am people friendly, appear dog friendly and can be cat tested. I am hoping to find my family but if they cannot be found I will need a new forever home and family to call my own. I will be available for adoption 3/20/26 at 9 am and my adoption fee is $114.

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We'll also keep you updated on BRUNO's adoption status with email updates.
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BRUNO

Mastiff

Male, 9 yrs 1 mo
Shelby, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-

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We'll also keep you updated on Angelina Ballerina's adoption status with email updates.
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Angelina Ballerina

Mastiff

Female, Adult
Holly Springs, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained,
Story
You can fill out an adoption application online on our official website. Online Adoption Application › Angelina’s story is about a second chance. She was rescued from the shelter with only hours left before being euthanized. When she was there, she was very scared. The shelter was a hard place for her, and she spent almost half of her young life there. Angelina is only 2 years old, and she is now learning what it feels like to be safe and cared for in her foster home. The scared dog who once sat quietly in a kennel is starting to relax and show her sweet, loving personality. She is a beautiful and gentle dog who just needs someone to give her a chance. With a patient and loving family, Angelina has everything it takes to become a wonderful companion and a loyal family dog. Visit this organization's web site to see any additional information available about this pet.April 6, 2026, 10:45 pm

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in North Carolina.

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Mastiff puppies and dogs in North Carolina cities

Mastiff Puppies near me Mastiff in Aberdeen Mastiff in Albemarle Mastiff in Angier Mastiff in Apex Mastiff in Archdale Mastiff in Asheboro Mastiff in Asheville Mastiff in Ayden Mastiff in Belmont Mastiff in Bessemer City Mastiff in Black Mountain Mastiff in Boiling Spring Lakes Mastiff in Boone Mastiff in Brevard Mastiff in Burlington Mastiff in Butner Mastiff in Carolina Beach Mastiff in Carrboro Mastiff in Cary Mastiff in Chapel Hill Mastiff in Charlotte Mastiff in Cherryville Mastiff in Clayton Mastiff in Clemmons Mastiff in Clinton Mastiff in Concord Mastiff in Conover Mastiff in Cornelius Mastiff in Davidson Mastiff in Dunn Mastiff in Durham Mastiff in Eden Mastiff in Edenton Mastiff in Elizabeth City Mastiff in Elon Mastiff in Erwin Mastiff in Fairview Mastiff in Farmville Mastiff in Fayetteville Mastiff in Fletcher Mastiff in Forest City Mastiff in Fuquay Varina Mastiff in Garner Mastiff in Gastonia Mastiff in Gibsonville Mastiff in Goldsboro Mastiff in Graham Mastiff in Granite Falls Mastiff in Greensboro Mastiff in Greenville Mastiff in Hamlet Mastiff in Harrisburg Mastiff in Havelock Mastiff in Henderson Mastiff in Hendersonville Mastiff in Hickory Mastiff in High Point Mastiff in Hillsborough Mastiff in Holly Springs Mastiff in Hope Mills Mastiff in Huntersville Mastiff in Indian Trail Mastiff in Jacksonville Mastiff in Kannapolis Mastiff in Kernersville Mastiff in Kill Devil Hills Mastiff in King Mastiff in Kings Mountain Mastiff in Kinston Mastiff in Knightdale Mastiff in Laurinburg Mastiff in Leland Mastiff in Lenoir Mastiff in Lewisville Mastiff in Lexington Mastiff in Lincolnton Mastiff in Lumberton Mastiff in Maggie Valley Mastiff in Marion Mastiff in Matthews Mastiff in Mebane Mastiff in Mills River Mastiff in Mint Hill Mastiff in Mocksville Mastiff in Monroe Mastiff in Mooresville Mastiff in Morehead City Mastiff in Morganton Mastiff in Morrisville Mastiff in Mount Airy Mastiff in Mount Holly Mastiff in Mount Olive Mastiff in Nashville Mastiff in New Bern Mastiff in Newport Mastiff in Newton Mastiff in Oak Island Mastiff in Oak Ridge Mastiff in Oxford Mastiff in Pinehurst Mastiff in Pineville Mastiff in Pleasant Garden Mastiff in Raleigh Mastiff in Reidsville Mastiff in Roanoke Rapids Mastiff in Rockingham Mastiff in Rocky Mount Mastiff in Roxboro Mastiff in Salisbury Mastiff in Sanford Mastiff in Sawmills Mastiff in Selma Mastiff in Shelby Mastiff in Siler City Mastiff in Smithfield Mastiff in Southern Pines Mastiff in Spring Lake Mastiff in Stallings Mastiff in Statesville Mastiff in Summerfield Mastiff in Tarboro Mastiff in Thomasville Mastiff in Trinity Mastiff in Unionville Mastiff in Valdese Mastiff in Wadesboro Mastiff in Wake Forest Mastiff in Walkertown Mastiff in Washington Mastiff in Waynesville Mastiff in Weddington Mastiff in Wendell Mastiff in Whiteville Mastiff in Williamston Mastiff in Wilmington Mastiff in Wilson Mastiff in Winston Salem Mastiff in Winterville Mastiff in Woodfin Mastiff in Zebulon

Mastiff shelters & rescues in North Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in North Carolina. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Peak Lab Rescue

Apex , NC 27502

Pet Types: dogs

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Rescue

Pawfect Match Rescue and Rehabilitation

Holly Springs , NC 27540

Pet Types: dogs

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Shelter

Wake County Animal Center

820 Beacon Lake Drive, Raleigh , NC 27610

Pet Types: cats, birds, dogs, rabbits, small animals

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Rescue

Carolina Animal Network

Wendell , NC 27591

Pet Types: cats, dogs

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Shelter

Cumberland County Animal Services

4704 Corporation Drive, Fayetteville , NC 28306

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

Wilson County Sheriffs Office Animal Enforcement

2506 Tucker Ct, WILSON , NC 27893

Pet Types: cats, birds, dogs, farm animals, rabbits, reptiles, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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