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Mastiff puppies and dogs in North Carolina

Looking for a Mastiff puppy or dog in North Carolina? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff in North Carolina Search for a Mastiff puppy or dog Mastiff puppies and dogs in North Carolina cities Mastiff shelters and rescues in North Carolina Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in North Carolina

Below are our newest added Mastiffs available for adoption in North Carolina. To see more adoptable Mastiffs in North Carolina, use the search tool below to enter specific criteria!
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Paws

Mastiff

Female, Adult
Cleveland, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Needs experienced adopter, House-trained,
Story
Meet Paws Paws was originally a foster, but after not getting along with our dogs, we learned that the rescue no longer had room for her. Unfortunately, that meant she would have to return to the shelter she came from, where she had previously been placed on the euthanasia list and would likely be placed back on it if returned. Like any animal lover would, we stepped in and adopted her. However, we're now searching for the perfect forever home for this sweet girl. At 104 pounds, Paws is nothing but love, affection, and cuddles. If you're looking for a giant snuggle buddy, she's your girl! Come meet this beautiful soul and give her the loving life she deserves.

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JANE

Mastiff

Female, 4 yrs
Charlotte, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
- Cutie with a wagging nub tail- Very treat motivated, knows sit- Enjoys scratches and searching through treat pouches- Loves finding a spot of grass to roll in- Can be strong on leash at times

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Dozer

Mastiff

Male, Young
Goldsboro, NC
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Not good with dogs, House-trained,
Story
Dozer is a great dog, who is house broken and loves to lay around all day. Since he has matured, he does not get along with our male golden retriever, but absolutely loves our female golden retriever. We have a cat, but I have never seen them interact (the cat lives upstairs). He is a free feeder, we just put a large bowl of food out and he self regulates. He is a beloved member of our family, but the golden has been here a lot longer. We hope to find someone who will love him as much as we do.

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Needs Home Fast
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Subwoofer

Mastiff

Male, 5 mos
Gastonia, NC
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
-
Story
-

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Photo of Gunner

Gunner

Mastiff/Labrador Retriever

Male, Adult
Pittsboro, NC
Size
(when grown) -
Details
-
Story
You can fill out an adoption application online on our official website.This animal is currently at the Randolph County Animal Shelter. Please apply today! https://www.randolphcountync.gov/FormCenter/Animal-Services-7/Adoption-Application-61This animal is currently at the Randolph County Animal Shelter.  Please apply today!  https://www.randolphcountync.gov/FormCenter/Animal-Services-7/Adoption-Application-61 Main number - 336-683-8235 Hours of operation: Monday - Friday (Closed  1st and 3rd Wednesday of the month) Open the first Saturday of each month from 10am-1pm. Animal adoption 9 - 5:30 pm Physical Address 1370 County Land Road Randleman , NC 27317 Adoption fees include combo and rabies vaccination, appropriate heath testing, deworming, spay and neuter, and microchipping. Male Dog $110 Female Dog $120 Male Cat $90 Female Cat $100Visit this organization's web site to see any additional information available about this pet.June 19, 2026, 12:32 pm

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Angelina Ballerina

Mastiff

Female, Adult
Holly Springs, NC
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained,
Story
You can fill out an adoption application online on our official website. Online Adoption Application › Angelia | 2 years old | 65lbs | Good with Dogs | Good with Older Kids | Housetrained Angelina’s story is about a second chance. She was rescued from the shelter with only hours left before being euthanized. When she was there, she was very scared. The shelter was a hard place for her, and she spent almost half of her young life there. Angelina is only 2 years old, and she is now learning what it feels like to be safe and cared for in her foster home. The scared dog who once sat quietly in a kennel is starting to relax and show her sweet, loving personality. She is a beautiful and gentle dog who just needs someone to give her a chance. With a patient and loving family, Angelina has everything it takes to become a wonderful companion and a loyal family dog. The adoption fee is $400, which covers food, vetting, microchip and the spay/neuter surgery performed by a rescue-affiliated vet.  All dogs receive a wellness visit and are up to date on shots appropriate for age.  Breed and size is Pawfect Match Rescue's best guess and not guaranteed. Please go to https://www.pawfectmatch.org/animals/search? and search on the dog name to see more photos, browse the profile, and complete an applicationVisit this organization's web site to see any additional information available about this pet.June 19, 2026, 6:49 pm

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in North Carolina.

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Mastiff puppies and dogs in North Carolina cities

Mastiff Puppies near me Mastiff in Aberdeen Mastiff in Albemarle Mastiff in Angier Mastiff in Apex Mastiff in Archdale Mastiff in Asheboro Mastiff in Asheville Mastiff in Ayden Mastiff in Belmont Mastiff in Bessemer City Mastiff in Black Mountain Mastiff in Boiling Spring Lakes Mastiff in Boone Mastiff in Brevard Mastiff in Burlington Mastiff in Butner Mastiff in Carolina Beach Mastiff in Carrboro Mastiff in Cary Mastiff in Chapel Hill Mastiff in Charlotte Mastiff in Cherryville Mastiff in Clayton Mastiff in Clemmons Mastiff in Clinton Mastiff in Concord Mastiff in Conover Mastiff in Cornelius Mastiff in Davidson Mastiff in Dunn Mastiff in Durham Mastiff in Eden Mastiff in Edenton Mastiff in Elizabeth City Mastiff in Elon Mastiff in Erwin Mastiff in Fairview Mastiff in Farmville Mastiff in Fayetteville Mastiff in Fletcher Mastiff in Forest City Mastiff in Fuquay Varina Mastiff in Garner Mastiff in Gastonia Mastiff in Gibsonville Mastiff in Goldsboro Mastiff in Graham Mastiff in Granite Falls Mastiff in Greensboro Mastiff in Greenville Mastiff in Hamlet Mastiff in Harrisburg Mastiff in Havelock Mastiff in Henderson Mastiff in Hendersonville Mastiff in Hickory Mastiff in High Point Mastiff in Hillsborough Mastiff in Holly Springs Mastiff in Hope Mills Mastiff in Huntersville Mastiff in Indian Trail Mastiff in Jacksonville Mastiff in Kannapolis Mastiff in Kernersville Mastiff in Kill Devil Hills Mastiff in King Mastiff in Kings Mountain Mastiff in Kinston Mastiff in Knightdale Mastiff in Laurinburg Mastiff in Leland Mastiff in Lenoir Mastiff in Lewisville Mastiff in Lexington Mastiff in Lincolnton Mastiff in Lumberton Mastiff in Maggie Valley Mastiff in Marion Mastiff in Matthews Mastiff in Mebane Mastiff in Mills River Mastiff in Mint Hill Mastiff in Mocksville Mastiff in Monroe Mastiff in Mooresville Mastiff in Morehead City Mastiff in Morganton Mastiff in Morrisville Mastiff in Mount Airy Mastiff in Mount Holly Mastiff in Mount Olive Mastiff in Nashville Mastiff in New Bern Mastiff in Newport Mastiff in Newton Mastiff in Oak Island Mastiff in Oak Ridge Mastiff in Oxford Mastiff in Pinehurst Mastiff in Pineville Mastiff in Pleasant Garden Mastiff in Raleigh Mastiff in Reidsville Mastiff in Roanoke Rapids Mastiff in Rockingham Mastiff in Rocky Mount Mastiff in Roxboro Mastiff in Salisbury Mastiff in Sanford Mastiff in Sawmills Mastiff in Selma Mastiff in Shelby Mastiff in Siler City Mastiff in Smithfield Mastiff in Southern Pines Mastiff in Spring Lake Mastiff in Stallings Mastiff in Statesville Mastiff in Summerfield Mastiff in Tarboro Mastiff in Thomasville Mastiff in Trinity Mastiff in Unionville Mastiff in Valdese Mastiff in Wadesboro Mastiff in Wake Forest Mastiff in Walkertown Mastiff in Washington Mastiff in Waynesville Mastiff in Weddington Mastiff in Wendell Mastiff in Whiteville Mastiff in Williamston Mastiff in Wilmington Mastiff in Wilson Mastiff in Winston Salem Mastiff in Winterville Mastiff in Woodfin Mastiff in Zebulon

Mastiff shelters & rescues in North Carolina

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in North Carolina. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Shelter

Gaston County Animal Care and Enforcement

1491 Business Park Court, Gastonia , NC 28052

Pet Types: cats, dogs

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Shelter

Charlotte Mecklenburg Animal Care & Control

8315 Byrum Dr, Charlotte , NC 28217

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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