Mastiff Adoption in Orange, CA: Mastiff Puppies for Sale in Orange, CA

Adopt a Mastiff near you in Orange, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Orange, California

These Mastiffs are available for adoption close to Orange, California.

Rocksteady

Mastiff Cane Corso

Male, Young

Placentia, CA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Not good with cats, House-trained,

Story

Very lovable and energetic Corso mastiff mix. Very loyal and protective of its owner. Can lay on the couch with you all day watching tv or go hike a trail. I have his brother also and my landlord won’t let me keep two in my apt anymore she’s getting police and courts involved now so I agreed to rehome one of them.

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Moose (Courtesy Post) - Adopt Me!

Mastiff

Male, Adult

Lake Forest, CA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs, House-trained, Spayed or Neutered,

Story

This handsome big guy is Moose, a sweet 2-year-old pup tipping the scales at 97 lbs of love! Moose has had lots of training under his belt and is fully crate trained, walks beautifully on leash, and is great with other dogs.Moose is neutered, up-to-date on vaccines, and ready to find his forever home. While he’s made great progress, Moose is still a bit timid and sensitive, so he’s looking for a calmer household where he can continue to blossom at his own pace. Because of his gentle, shy nature, he’d do best in a home with older kids who understand how to give him space when he needs it.Moose would love a family who can provide a quiet, structured environment where he can feel safe, loved, and part of the pack. If you’re looking for a loyal, kind-hearted companion with a big heart (and paws to match!), Moose may be the one for you! Located in Los Angeles, CAMarch 7, 2026, 3:29 pm

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Dudley-Special Needs - Adopt Me!

Mastiff Labrador Retriever

Male, Adult

Lake Forest, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

He might not hear you, he may not see you, he may be missing all his teeth… but Dudley is single and ready to mingle Our sweet, special boy Dudley is still waiting for his forever home (and yes—he has his own IG! @dudleyfindsahome).At 3 years old and 65 lbs, he loves walks, playtime, and enrichment, and is easygoing in the home. He relies on gentle touch cues to communicate and is affectionate, funny, and incredibly sweet.Dudley is thriving in a multi-pet, kid-friendly foster home—proof of just how adaptable he is.Not high maintenance—just highly special.April 29, 2026, 5:03 pm

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Brody

Mastiff Pit Bull Terrier

Male, 5 yrs

La Habra, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Not good with kids, Good with dogs, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Hi all! I’m Brody! I’m 4 years old and have been told I’m a total meat head who isn’t always aware just how big he is. I hear everyone calling me a handsome beefcake, which I can only imagine is a good thing. ☺️So far, everyone thinks I’m a mastiff/pit bull mix, hence the beefcake comments, but we’re not 100% sure as we haven’t done a DNA test. Regardless of my breed, I know I’m 100% handsome, because my foster mama tells me every day! 😍 I’ve got a big ole head, and a giant heart to match. 🫶 Not only am I easy on the eyes, but I’m also fully trained! I’ve got my basic obedience down, walk great on a leash and am crate trained. I love ALL dogs, even the littles, and my motto is #BALLISLIFE! I could play ball EVERY DAY and would love a home with a family who will play with me! But not to worry! I’m also perfectly content with some R&R at home and can be a lazy potato. My ideal home would be with a family who is patient and kind. I’ve had a lot happen to me in my 4 years on this earth, so I can be nervous meeting new people. However, I can also warm up really fast, and once you’re in, you’re in forever and we’ll be the bestest friends forever! 👯🤗 I’d also do best in a home with strong leaders, because let’s face it… I don’t like having to make choices. I mean, can ya blame me? Making decisions is a tiring thing, and why spend time doing that when I could be having fun! I’m fully vetted, neutered, current on all vaccines, microchipped and looking for my forever family.

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KARMA

Mastiff

Female, 9 mos

Huntington Beach, CA

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Story

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Riley (C000-321) - Chino Hills Location

Mastiff Mixed Breed (Large)

Male, 3 yrs 10 mos

Chino Hills, CA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

House-trained, Spayed or Neutered,

Story

Riley is a sweet, gentle soul with a calm and loving nature. He enjoys long, peaceful walks, soaking up the sunshine, and happily rolling around in the grass for the best back scratches. Riley is wonderfully attentive and food-motivated—he’ll politely sit like a perfect gentleman the moment he senses a treat coming. He has a playful side and truly cherishes affection, but he’s just as content curling up on a cozy bed for a well-earned nap after some outdoor time. With his beautiful balance of relaxed and playful energy, Riley would thrive with a confident, caring person who’s ready to give him the love and attention he’s been patiently waiting for.

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Mastiff puppies and dogs in Orange, California

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Mastiff puppies and dogs in Orange, California

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Adopt a Mastiff near you in Orange, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Orange, California

These Mastiffs are available for adoption close to Orange, California.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Orange, California

Mastiff shelters & rescues in Orange, California

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics