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Mastiff puppies and dogs in Orange, California

Looking for a Mastiff puppy or dog in Orange, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Orange, California Other pups in Orange, California Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Orange, California Mastiff shelters and rescues in Orange, California Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Orange, California

These Mastiffs are available in Orange, California.
We'll also keep you updated on Sedona's adoption status with email updates.
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Sedona

Mastiff Shepherd (Unknown Type)

Female, Puppy
Irvine, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
Meet Sedona!Sedona is a 12‑week‑old Shepherd mix with a happy heart and a love‑everyone personality. She’s social, playful, and always excited to meet new friends — people, dogs, anyone who will say hello. She’s going to be a big girl when she grows up, and she’s already showing off that sweet, confident Shepherd charm. Sedona is ready for a family who will help her learn, explore, and grow into the amazing dog she’s meant to be. For more information, visit fochp.org.   For a complete list of our pets and photos please visit our website fochp.org  March 30, 2026, 4:52 pm

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Or, how about these Mastiffs in cities near Orange, California

These Mastiffs are available for adoption close to Orange, California.
We'll also keep you updated on RECON's adoption status with email updates.
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RECON

Mastiff

Male, Adult
Tustin, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
March 7, 2026, 12:50 pm

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We'll also keep you updated on HOWARD's adoption status with email updates.
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HOWARD

Mastiff

Male, Adult
Tustin, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
March 7, 2026, 12:50 pm

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We'll also keep you updated on Sedona's adoption status with email updates.
Photo of Sedona

Sedona

Mastiff Shepherd (Unknown Type)

Female, Puppy
Irvine, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,
Story
Meet Sedona!Sedona is a 12‑week‑old Shepherd mix with a happy heart and a love‑everyone personality. She’s social, playful, and always excited to meet new friends — people, dogs, anyone who will say hello. She’s going to be a big girl when she grows up, and she’s already showing off that sweet, confident Shepherd charm. Sedona is ready for a family who will help her learn, explore, and grow into the amazing dog she’s meant to be. For more information, visit fochp.org.   For a complete list of our pets and photos please visit our website fochp.org  March 30, 2026, 4:52 pm

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We'll also keep you updated on WAGS-Stray-20980's adoption status with email updates.
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WAGS-Stray-20980

Mastiff Mixed Breed (Medium)

Female, 3 yrs 9 mos
Westminster, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
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We'll also keep you updated on Moose (Courtesy Post) - Adopt Me!'s adoption status with email updates.
Photo of Moose (Courtesy Post) - Adopt Me!

Moose (Courtesy Post) - Adopt Me!

Mastiff

Male, Adult
Lake Forest, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered,
Story
This handsome big guy is Moose, a sweet 2-year-old pup tipping the scales at 97 lbs of love! Moose has had lots of training under his belt and is fully crate trained, walks beautifully on leash, and is great with other dogs.Moose is neutered, up-to-date on vaccines, and ready to find his forever home. While he’s made great progress, Moose is still a bit timid and sensitive, so he’s looking for a calmer household where he can continue to blossom at his own pace. Because of his gentle, shy nature, he’d do best in a home with older kids who understand how to give him space when he needs it.Moose would love a family who can provide a quiet, structured environment where he can feel safe, loved, and part of the pack. If you’re looking for a loyal, kind-hearted companion with a big heart (and paws to match!), Moose may be the one for you! Located in Los Angeles, CAMarch 7, 2026, 3:29 pm

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We'll also keep you updated on Dudley-Special Needs - Adopt Me!'s adoption status with email updates.
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Dudley-Special Needs - Adopt Me!

Mastiff Labrador Retriever

Male, Adult
Lake Forest, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Dudley is absolutely amazing, and it’s surprising he hasn’t found his forever home yet. As a partially blind and deaf dog, he relies on his human for gentle physical cues—but he’s confident, easy-going, and thrives with the right guidance. His “different abilities” don’t slow him down; he enjoys walks, playtime, and enrichment, showing he’s far from high-maintenance.Affectionate, gentle, and funny, Dudley communicates with soft “bonks” and responds to touch cues. He’s social and already thriving in a multi-pet, kid-friendly foster home. Seeing him navigate, play, and interact with others really shows his personality.Dudley is perfect for adopters who understand special-needs dogs and want a calm, loving companion ready to shine in a patient, supportive home.March 16, 2026, 8:54 pm

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Orange, California.

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Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Alhambra, CA Mastiff in Aliso Viejo, CA Mastiff in Anaheim, CA Mastiff in Arcadia, CA Mastiff in Artesia, CA Mastiff in Azusa, CA Mastiff in Baldwin Park, CA Mastiff in Bell, CA Mastiff in Bellflower, CA Mastiff in Bell Gardens, CA Mastiff in Brea, CA Mastiff in Buena Park, CA Mastiff in Canyon Lake, CA Mastiff in Carson, CA Mastiff in Cerritos, CA Mastiff in Chino, CA Mastiff in Chino Hills, CA Mastiff in Claremont, CA Mastiff in Colton, CA Mastiff in Commerce, CA Mastiff in Compton, CA Mastiff in Corona, CA Mastiff in Costa Mesa, CA Mastiff in Covina, CA Mastiff in Cudahy, CA Mastiff in Cypress, CA Mastiff in Dana Point, CA Mastiff in Diamond Bar, CA Mastiff in Downey, CA Mastiff in Duarte, CA Mastiff in El Monte, CA Mastiff in Fontana, CA Mastiff in Fountain Valley, CA Mastiff in Fullerton, CA Mastiff in Gardena, CA Mastiff in Garden Grove, CA Mastiff in Glendora, CA Mastiff in Grand Terrace, CA Mastiff in Hawaiian Gardens, CA Mastiff in Hawthorne, CA Mastiff in Huntington Beach, CA Mastiff in Huntington Park, CA Mastiff in Inglewood, CA Mastiff in Irvine, CA Mastiff in Laguna Beach, CA Mastiff in Laguna Hills, CA Mastiff in Laguna Niguel, CA Mastiff in Laguna Woods, CA Mastiff in La Habra, CA Mastiff in La Habra Heights, CA Mastiff in Lake Elsinore, CA Mastiff in Lake Forest, CA Mastiff in Lakewood, CA Mastiff in La Mirada, CA Mastiff in La Palma, CA Mastiff in La Puente, CA Mastiff in La Verne, CA Mastiff in Lawndale, CA Mastiff in Lomita, CA Mastiff in Long Beach, CA Mastiff in Los Alamitos, CA Mastiff in Los Angeles, CA Mastiff in Lynwood, CA Mastiff in Maywood, CA Mastiff in Mission Viejo, CA Mastiff in Monrovia, CA Mastiff in Montclair, CA Mastiff in Montebello, CA Mastiff in Monterey Park, CA Mastiff in Moreno Valley, CA Mastiff in Murrieta, CA Mastiff in Newport Beach, CA Mastiff in Norco, CA Mastiff in Norwalk, CA Mastiff in Ontario, CA Mastiff in Palos Verdes Estates, CA Mastiff in Paramount, CA Mastiff in Pasadena, CA Mastiff in Perris, CA Mastiff in Pico Rivera, CA Mastiff in Placentia, CA Mastiff in Pomona, CA Mastiff in Rancho Cucamonga, CA Mastiff in Rancho Palos Verdes, CA Mastiff in Rancho Santa Margarita, CA Mastiff in Redondo Beach, CA Mastiff in Rialto, CA Mastiff in Riverside, CA Mastiff in Rolling Hills Estates, CA Mastiff in Rosemead, CA Mastiff in San Bernardino, CA Mastiff in San Clemente, CA Mastiff in San Dimas, CA Mastiff in San Gabriel, CA Mastiff in San Juan Capistrano, CA Mastiff in San Marino, CA Mastiff in Santa Ana, CA Mastiff in Santa Fe Springs, CA Mastiff in Seal Beach, CA Mastiff in Sierra Madre, CA Mastiff in Signal Hill, CA Mastiff in South El Monte, CA Mastiff in South Gate, CA Mastiff in South Pasadena, CA Mastiff in Stanton, CA Mastiff in Temple City, CA Mastiff in Torrance, CA Mastiff in Tustin, CA Mastiff in Upland, CA Mastiff in Villa Park, CA Mastiff in Walnut, CA Mastiff in West Covina, CA Mastiff in Westminster, CA Mastiff in Whittier, CA Mastiff in Yorba Linda, CA

Related breeds in Orange, California

Bullmastiffs in Orange, California Neapolitan Mastiffs in Orange, California Saint Bernards in Orange, California

Mastiff shelters & rescues in Orange, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Orange, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

3.6 miles

OC Animal Care

1630 Victory Road, Tustin, CA 92782

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

4.3 miles

Friends of Orange County's Homeless Pets

foster homes, THIS IS NOT A SHELTER, Irvine, CA 92865

Pet Types: cats, dogs, small animals

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Shelter

11.5 miles

WAGS (Westminster Adoption Group and Services)

6621 Westminster Blvd, Goldenwest/Westminster, Westminster, CA 92683

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

12.2 miles

The Little Red Dog, Inc

Lake Forest, CA 92630

Pet Types: cats, dogs, rabbits, small animals

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Rescue

12.9 miles

Orange County Pit Bull Rescue

PO Box 3738, La Habra, CA 90632

Pet Types: dogs

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Shelter

12.9 miles

Orange County Humane Society

21632 Newland St, (Open during Newland St. Construction), Huntington Beach, CA 92646

Pet Types: cats, dogs

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Rescue

15.1 miles

Priceless Pets

2587 C Chino Hills Parkway, Chino Hills, CA 91709

Pet Types: cats, dogs, rabbits, reptiles, small animals

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Shelter

18.5 miles

Long Beach Animal Care Services

7700 E Spring St., Long Beach, CA 90815

Pet Types: cats, birds, dogs, rabbits, small animals

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Shelter

20.1 miles

West End Shelter for Animals

Ontario, CA 91761

Pet Types: cats, dogs

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Shelter

24.4 miles

Riverside County Animal Control - Riverside Shelter

6851 Van Buren Blvd, Jurupa Valley, CA 92509

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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