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Mastiff puppies and dogs in Orange, California

Looking for a Mastiff puppy or dog in Orange, California? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Orange, California Other pups in Orange, California Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Orange, California Mastiff shelters and rescues in Orange, California Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Orange, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Orange, California

These Mastiffs are available for adoption close to Orange, California.
Photo of INDIANA

INDIANA

Mastiff

Male, Adult
Tustin, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
October 30, 2026, 10:41 pm

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Baby Huey

Mastiff

Male, 4 yrs 9 mos
Tustin, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
-

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Photo of RIVER

RIVER

Mastiff

Male, 1 yr
Irvine, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Boo! Did I scare you? Don’t worry, I’m just River, your friendly neighborhood gentle giant! I may be a BIG boy, but underneath all this dog is an even bigger sweetheart with a goofy personality that’s sure to keep you laughing. I’m looking for a forever home with family members ages 16 and up who have plenty of love to give and don’t mind having a giant goofball around. So, what do you say? Skip the tricks, I’ve got all the treats (and cuddles) you could ever need!

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Photo of Moose (Courtesy Post) - Adopt Me!

Moose (Courtesy Post) - Adopt Me!

Mastiff

Male, Adult
Lake Forest, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered,
Story
This handsome big guy is Moose, a sweet 2-year-old pup tipping the scales at 97 lbs of love! Moose has had lots of training under his belt and is fully crate trained, walks beautifully on leash, and is great with other dogs.Moose is neutered, up-to-date on vaccines, and ready to find his forever home. While he’s made great progress, Moose is still a bit timid and sensitive, so he’s looking for a calmer household where he can continue to blossom at his own pace. Because of his gentle, shy nature, he’d do best in a home with older kids who understand how to give him space when he needs it.Moose would love a family who can provide a quiet, structured environment where he can feel safe, loved, and part of the pack. If you’re looking for a loyal, kind-hearted companion with a big heart (and paws to match!), Moose may be the one for you! Located in Los Angeles, CAMarch 7, 2026, 3:29 pm

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Photo of Charlie

Charlie

Mastiff

Male, 2 yrs
Huntington Beach, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Charlie is a loving and gentle boy! He likes to go on walks and cuddle with people. He is being trained by Redemption Tails, and his adoption includes a consultation.

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Special Needs
Photo of Bear

Bear

Mastiff

Male, Puppy
Chino Hills, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Needs special attention, Needs experienced adopter, House-trained, Shots are up-to-date,
Story
Bear is an 11-month-old Mastiff, possibly mixed with Cane Corso. He's brown, about 120 lbs, and still growing, with a heart just as big. He loves his people, gets along well with other dogs, is fully house-trained, and walks nicely on leash with a prong collar. The truth is, Bear doesn't know how big he is. He still thinks he's a lap dog, and his love comes at you at full speed. My elderly parent visits often, and so do my young nieces. As sweet as Bear is, one happy lean or excited greeting could knock any of them down and cause a serious injury. I want to be fully transparent about his health. Bear has a seizure condition that his vet is actively managing. He's on levetiracetam and has had three episodes over the past three months or so. He's a happy, normal dog between episodes, and I'll provide complete vet records and stay available to his new family for any questions.We are not surrendering him to a shelter. Bear will stay safe at home with us until the right match is found.

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Orange, California.

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Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Alhambra, CA Mastiff in Aliso Viejo, CA Mastiff in Anaheim, CA Mastiff in Arcadia, CA Mastiff in Artesia, CA Mastiff in Azusa, CA Mastiff in Baldwin Park, CA Mastiff in Bell, CA Mastiff in Bellflower, CA Mastiff in Bell Gardens, CA Mastiff in Brea, CA Mastiff in Buena Park, CA Mastiff in Canyon Lake, CA Mastiff in Carson, CA Mastiff in Cerritos, CA Mastiff in Chino, CA Mastiff in Chino Hills, CA Mastiff in Claremont, CA Mastiff in Colton, CA Mastiff in Commerce, CA Mastiff in Compton, CA Mastiff in Corona, CA Mastiff in Costa Mesa, CA Mastiff in Covina, CA Mastiff in Cudahy, CA Mastiff in Cypress, CA Mastiff in Dana Point, CA Mastiff in Diamond Bar, CA Mastiff in Downey, CA Mastiff in Duarte, CA Mastiff in El Monte, CA Mastiff in Fontana, CA Mastiff in Fountain Valley, CA Mastiff in Fullerton, CA Mastiff in Gardena, CA Mastiff in Garden Grove, CA Mastiff in Glendora, CA Mastiff in Grand Terrace, CA Mastiff in Hawaiian Gardens, CA Mastiff in Hawthorne, CA Mastiff in Huntington Beach, CA Mastiff in Huntington Park, CA Mastiff in Inglewood, CA Mastiff in Irvine, CA Mastiff in Laguna Beach, CA Mastiff in Laguna Hills, CA Mastiff in Laguna Niguel, CA Mastiff in Laguna Woods, CA Mastiff in La Habra, CA Mastiff in La Habra Heights, CA Mastiff in Lake Elsinore, CA Mastiff in Lake Forest, CA Mastiff in Lakewood, CA Mastiff in La Mirada, CA Mastiff in La Palma, CA Mastiff in La Puente, CA Mastiff in La Verne, CA Mastiff in Lawndale, CA Mastiff in Lomita, CA Mastiff in Long Beach, CA Mastiff in Los Alamitos, CA Mastiff in Los Angeles, CA Mastiff in Lynwood, CA Mastiff in Maywood, CA Mastiff in Mission Viejo, CA Mastiff in Monrovia, CA Mastiff in Montclair, CA Mastiff in Montebello, CA Mastiff in Monterey Park, CA Mastiff in Moreno Valley, CA Mastiff in Murrieta, CA Mastiff in Newport Beach, CA Mastiff in Norco, CA Mastiff in Norwalk, CA Mastiff in Ontario, CA Mastiff in Palos Verdes Estates, CA Mastiff in Paramount, CA Mastiff in Pasadena, CA Mastiff in Perris, CA Mastiff in Pico Rivera, CA Mastiff in Placentia, CA Mastiff in Pomona, CA Mastiff in Rancho Cucamonga, CA Mastiff in Rancho Palos Verdes, CA Mastiff in Rancho Santa Margarita, CA Mastiff in Redondo Beach, CA Mastiff in Rialto, CA Mastiff in Riverside, CA Mastiff in Rolling Hills Estates, CA Mastiff in Rosemead, CA Mastiff in San Bernardino, CA Mastiff in San Clemente, CA Mastiff in San Dimas, CA Mastiff in San Gabriel, CA Mastiff in San Juan Capistrano, CA Mastiff in San Marino, CA Mastiff in Santa Ana, CA Mastiff in Santa Fe Springs, CA Mastiff in Seal Beach, CA Mastiff in Sierra Madre, CA Mastiff in Signal Hill, CA Mastiff in South El Monte, CA Mastiff in South Gate, CA Mastiff in South Pasadena, CA Mastiff in Stanton, CA Mastiff in Temple City, CA Mastiff in Torrance, CA Mastiff in Tustin, CA Mastiff in Upland, CA Mastiff in Villa Park, CA Mastiff in Walnut, CA Mastiff in West Covina, CA Mastiff in Westminster, CA Mastiff in Whittier, CA Mastiff in Yorba Linda, CA

Related breeds in Orange, California

Bullmastiffs in Orange, California Neapolitan Mastiffs in Orange, California Saint Bernards in Orange, California

Mastiff shelters & rescues in Orange, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Orange, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

3.6 miles

OC Animal Care

1630 Victory Road, Tustin, CA 92782

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

3.6 miles

No Stray Left Behind

Tustin, CA 92782

Pet Types: dogs

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Shelter

7.6 miles

Irvine Animal Care Center

6443 Oak Canyon, Irvine, CA 92618

Pet Types: cats, birds, dogs, rabbits, small animals

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Rescue

12.2 miles

The Little Red Dog, Inc

Lake Forest, CA 92630

Pet Types: cats, dogs, rabbits, small animals

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Rescue

12.9 miles

TREAT Pet Rescue

Huntington Beach, CA 92646

Pet Types: cats, dogs

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Rescue

15.1 miles

Priceless Pets

2587 Chino Hills Pkwy, Unit C, Chino Hills, CA 91709

Pet Types: cats, dogs, rabbits, reptiles, small animals

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Shelter

15.9 miles

Corona Animal Shelter

1330 Magnolia Ave, Corona, CA 92879

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

16.7 miles

SoCal Surviving Strays Animal Rescue

Norco, CA 92860

Pet Types: cats, dogs

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Shelter

17.6 miles

Inland Valley Humane Society & S.P.C.A.

500 Humane Way, Pomona, CA 91766

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

18.5 miles

Long Beach Animal Care Services

7700 E Spring St., Long Beach, CA 90815

Pet Types: cats, birds, dogs, rabbits, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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