Adopt
Rehome
Menu Hamburger Icon

Mastiff puppies and dogs in Irvine, California

Looking for a Mastiff puppy or dog in Irvine, California? Adopt a Pet can help you find an adorable Mastiff near you.

Picture of Mastiff

Learn More:

Adopt a Mastiff near you Mastiff in cities near Irvine, California Other pups in Irvine, California Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Irvine, California Mastiff shelters and rescues in Irvine, California Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Irvine, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Irvine, California

These Mastiffs are available for adoption close to Irvine, California.
We'll also keep you updated on RECON's adoption status with email updates.
Photo of RECON

RECON

Mastiff

Male, Adult
Tustin, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
December 17, 2025, 7:17 pm

Learn More

Small right facing arrow
We'll also keep you updated on OBIE's adoption status with email updates.
Photo of OBIE

OBIE

Mastiff

Male, Adult
Tustin, CA
Size
(when grown) -
Details
Spayed or Neutered,
Story
January 13, 2026, 9:14 pm

Learn More

Small right facing arrow
We'll also keep you updated on HOWARD's adoption status with email updates.
Photo of HOWARD

HOWARD

Mastiff

Male, Adult
Tustin, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
February 23, 2026, 9:08 pm

Learn More

Small right facing arrow
We'll also keep you updated on Moose (Courtesy Post) - Adopt Me!'s adoption status with email updates.
Photo of Moose (Courtesy Post) - Adopt Me!

Moose (Courtesy Post) - Adopt Me!

Mastiff

Male, Adult
Lake Forest, CA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered,
Story
This handsome big guy is Moose, a sweet 2-year-old pup tipping the scales at 97 lbs of love! Moose has had lots of training under his belt and is fully crate trained, walks beautifully on leash, and is great with other dogs.Moose is neutered, up-to-date on vaccines, and ready to find his forever home. While he’s made great progress, Moose is still a bit timid and sensitive, so he’s looking for a calmer household where he can continue to blossom at his own pace. Because of his gentle, shy nature, he’d do best in a home with older kids who understand how to give him space when he needs it.Moose would love a family who can provide a quiet, structured environment where he can feel safe, loved, and part of the pack. If you’re looking for a loyal, kind-hearted companion with a big heart (and paws to match!), Moose may be the one for you! Located in Los Angeles, CAJanuary 15, 2026, 9:23 pm

Learn More

Small right facing arrow
We'll also keep you updated on Dudley-Special Needs - Adopt Me!'s adoption status with email updates.
Photo of Dudley-Special Needs - Adopt Me!

Dudley-Special Needs - Adopt Me!

Mastiff Labrador Retriever

Male, Adult
Lake Forest, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Dudley born in 2023 is a sweet, affectionate boy weighing around 65 lbs. Partially blind and deaf, he doesn’t let that slow him down. He walks nicely on leash and just needs gentle guidance to avoid obstacles — if he loses track, he’ll give your leg a soft “bonk” to reorient himself.Dudley enjoys short walks, stuffed toys, and being outside. After a 20-minute stroll, he’s ready to chill for the rest of the day. He lets you know when he needs to potty and loves foraging for treats as enrichment.He’s social with other dogs (especially if they make physical contact), and he’s currently thriving in a foster home with other dogs, cats, and kids. Dudley also responds to touch cues — a double tap on his bottom means “sit.”Dudley is looking for a patient, loving home to guide him safely and show him how wonderful life can be!February 4, 2026, 9:11 pm

Learn More

Small right facing arrow
We'll also keep you updated on Ranger's adoption status with email updates.
Photo of Ranger

Ranger

Mastiff American Pit Bull Terrier

Male, Adult
Fullerton, CA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained,
Story
Pitbull/Mastiff 5 year old male dog needs a good home. He is not neutered, vaccines unknown, previous owner was moving and couldn’t take him so we stepped in to foster until a home could be found. We have 3 dogs and live in an apartment, otherwise we would keep him. He is good around other dogs, friendly with people & kids and generally a big goofball. He is not crate trained, but is house trained. Please consider adopting him. No breeders, we are looking for a good home for him. Someone that will train him (he is very smart & trainable) and has a backyard that he can run around in.

Learn More

Small right facing arrow

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Irvine, California.

    an arrow icon
location arrow icon Current location
  • New York, NY
  • Los Angeles, CA
  • Houston, TX
  • Dallas, TX
  • Brooklyn, NY

Sorry, we can’t find that location! Please try again.

    Age
    an arrow icon

Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Alhambra, CA Mastiff in Aliso Viejo, CA Mastiff in Anaheim, CA Mastiff in Arcadia, CA Mastiff in Artesia, CA Mastiff in Azusa, CA Mastiff in Baldwin Park, CA Mastiff in Bell, CA Mastiff in Bellflower, CA Mastiff in Bell Gardens, CA Mastiff in Brea, CA Mastiff in Buena Park, CA Mastiff in Canyon Lake, CA Mastiff in Carson, CA Mastiff in Cerritos, CA Mastiff in Chino, CA Mastiff in Chino Hills, CA Mastiff in Claremont, CA Mastiff in Colton, CA Mastiff in Commerce, CA Mastiff in Compton, CA Mastiff in Corona, CA Mastiff in Costa Mesa, CA Mastiff in Covina, CA Mastiff in Cudahy, CA Mastiff in Cypress, CA Mastiff in Dana Point, CA Mastiff in Diamond Bar, CA Mastiff in Downey, CA Mastiff in Duarte, CA Mastiff in El Monte, CA Mastiff in Fontana, CA Mastiff in Fountain Valley, CA Mastiff in Fullerton, CA Mastiff in Gardena, CA Mastiff in Garden Grove, CA Mastiff in Glendora, CA Mastiff in Grand Terrace, CA Mastiff in Hawaiian Gardens, CA Mastiff in Huntington Beach, CA Mastiff in Huntington Park, CA Mastiff in Laguna Beach, CA Mastiff in Laguna Hills, CA Mastiff in Laguna Niguel, CA Mastiff in Laguna Woods, CA Mastiff in La Habra, CA Mastiff in La Habra Heights, CA Mastiff in Lake Elsinore, CA Mastiff in Lake Forest, CA Mastiff in Lakewood, CA Mastiff in La Mirada, CA Mastiff in La Palma, CA Mastiff in La Puente, CA Mastiff in La Verne, CA Mastiff in Lomita, CA Mastiff in Long Beach, CA Mastiff in Los Alamitos, CA Mastiff in Los Angeles, CA Mastiff in Lynwood, CA Mastiff in Maywood, CA Mastiff in Mission Viejo, CA Mastiff in Monrovia, CA Mastiff in Montclair, CA Mastiff in Montebello, CA Mastiff in Monterey Park, CA Mastiff in Moreno Valley, CA Mastiff in Murrieta, CA Mastiff in Newport Beach, CA Mastiff in Norco, CA Mastiff in Norwalk, CA Mastiff in Ontario, CA Mastiff in Orange, CA Mastiff in Paramount, CA Mastiff in Pasadena, CA Mastiff in Perris, CA Mastiff in Pico Rivera, CA Mastiff in Placentia, CA Mastiff in Pomona, CA Mastiff in Rancho Cucamonga, CA Mastiff in Rancho Santa Margarita, CA Mastiff in Rialto, CA Mastiff in Riverside, CA Mastiff in Rosemead, CA Mastiff in San Bernardino, CA Mastiff in San Clemente, CA Mastiff in San Dimas, CA Mastiff in San Gabriel, CA Mastiff in San Juan Capistrano, CA Mastiff in San Marino, CA Mastiff in Santa Ana, CA Mastiff in Santa Fe Springs, CA Mastiff in Seal Beach, CA Mastiff in Sierra Madre, CA Mastiff in Signal Hill, CA Mastiff in South El Monte, CA Mastiff in South Gate, CA Mastiff in Stanton, CA Mastiff in Temple City, CA Mastiff in Torrance, CA Mastiff in Tustin, CA Mastiff in Upland, CA Mastiff in Villa Park, CA Mastiff in Walnut, CA Mastiff in West Covina, CA Mastiff in Westminster, CA Mastiff in Whittier, CA Mastiff in Yorba Linda, CA

Related breeds in Irvine, California

Bullmastiffs in Irvine, California Neapolitan Mastiffs in Irvine, California Saint Bernards in Irvine, California

Mastiff shelters & rescues in Irvine, California

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Irvine, California. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

2.4 miles

OC Animal Care

1630 Victory Road, Tustin, CA 92782

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

More an arrow icon

Rescue

8.1 miles

The Little Red Dog, Inc

Lake Forest, CA 92630

Pet Types: cats, dogs, rabbits, small animals

More an arrow icon

Rescue

17.1 miles

Orange County Pit Bull Rescue

PO Box 3738, La Habra, CA 90632

Pet Types: dogs

More an arrow icon

Rescue

17.2 miles

Priceless Pets

2587 C Chino Hills Parkway, Chino Hills, CA 91709

Pet Types: cats, dogs, rabbits, reptiles, small animals

More an arrow icon

Shelter

21.6 miles

Long Beach Animal Care Services

7700 E Spring St., Long Beach, CA 90815

Pet Types: cats, birds, dogs, rabbits, small animals

More an arrow icon

Shelter

21.7 miles

West End Shelter for Animals

Ontario, CA 91761

Pet Types: cats, dogs

More an arrow icon

Shelter

24.4 miles

Riverside County Animal Control - Riverside Shelter

6851 Van Buren Blvd, Jurupa Valley, CA 92509

Pet Types: cats, dogs

More an arrow icon

Shelter

25.4 miles

Friends of Upland Animal Shelter

1275 San Bernardino Road, Upland, CA 91786

Pet Types: cats, birds, dogs, rabbits, small animals

More an arrow icon

Shelter

26.2 miles

Rancho Cucamonga Animal Care and Adoption Center

11780 Arrow Route, Rancho Cucamonga, CA 91730

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

More an arrow icon

Shelter

30.2 miles

Animal Friends of the Valleys

33751 Mission Trail, Wildomar, CA 92595

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

More an arrow icon

Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

magnifying glass with cat and dog

Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

clipboard with list

Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

Learn More an arrow icon