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Mastiff puppies and dogs in Denver, Colorado

Looking for a Mastiff puppy or dog in Denver, Colorado? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Denver, Colorado

These Mastiffs are available in Denver, Colorado.
Photo of WARIO

WARIO

Mastiff

Male, 4 yrs 1 mo
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Wario`s foster parent says: Wario is a sweet and playful lover boy! Sweet, gentle, curious, energetic and handsome. He loves fetch. He is content to play on his own and wander about the yard but may do well with another dog as playmate as he has a lot of life in him and a love for other dogs. He has a good training foundation. I suspect he`d be a joyful and gentle addition to a family with children.* No small dogs or cats reccommended

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Special Needs
Photo of Sabrina

Sabrina

Mastiff American Bulldog

Female, 6 yrs 9 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Good with cats, Needs special attention, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Sabrina, a gentle 6-year-old Mastiff mix who’s in need of a special forever home. Sabrina is living with mast cell tumors (MCT) due to cancer and is currently on medication to keep her as comfortable as possible. She requires a loving home that is prepared to offer her hospice care and a peaceful environment. Sabrina can be shy with new people and may give a warning growl or snap if approached when she’s not ready. However, once she builds trust, she becomes deeply affectionate and very attached to her people. She gets along well with mellow dogs and will thrive in a calm household where she can feel safe and loved. If you have a compassionate heart and are ready to provide a supportive and caring home for a special dog like Sabrina, you’ll find a loyal and loving companion in her.

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Photo of Maxine

Maxine

Mastiff

Female, 3 yrs
Boulder, CO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
🐾 _Meet Maxine!_ 😍 This gentle giant is a sweet 3-year-old, 66-pound Mastiff mix with a heart of gold. Pulled from a shelter's at her final notice, she's now ready to shower YOU with love 🐾💕. Playful with humans and pups alike, Maxine's favorite thing is snuggling up for hugs and smacks. As a volunteer's fave at the shelter, she'd brighten anyone's day. Ready to make you her person? 😁 Let's get Maxine home!

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Photo of Monte aka Moose

Monte aka Moose

Boxer Mastiff

Male, 1 yr
Boulder, CO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, Shots are up-to-date,
Story
Moose is a 1-year-old Pitbull mix with a heart as big as his smile. This sweet boy is the perfect combination of playful, loving, and eager to be your best friend. He absolutely loves people and has shown that he enjoys spending time with other dogs too! Moose has a gentle, affectionate personality and is always ready to share his love with those around him. Whether he’s going for a walk, playing with his furry friends, or simply relaxing by your side, Moose is happiest when he’s with his people. This handsome boy is looking for a forever home where he can continue to be loved, spoiled, and treated like the special dog he is. If you’re looking for a loyal companion with a sweet personality, Moose may be the perfect addition to your family!

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Photo of Zen

Zen

Neapolitan Mastiff Mastiff

Male, 6 yrs
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Needs experienced adopter, Spayed or Neutered, Shots are up-to-date,
Story
Zen is a 6-year-old male Neo Mastiff mix who’s as big-hearted as he is big in stature. Rescued from a shelter after his previous owners surrendered him for being “too big,” Zen is now on the hunt for his forever home where he can truly shine. Zen is a sweet, playful giant with a lot of energy for his breed. He’s very intelligent and learns quickly, making him a joy to train. However, Zen prefers to be the only dog in the home; he can get jealous and aggressive with other dogs, wanting all the attention for himself. When he's your one and only, he’s incredibly loving and will shower you with affection. Though he’s not reactive to other dogs on leash, Zen does best in a home without canine companions. He appreciates careful introductions to new people, especially those who approach unexpectedly. Zen’s ideal owner will be someone experienced with his breed and capable of continuing his training and socialization. If you’re ready to welcome a devoted and energetic companion into your life, Zen could be the perfect fit. He’s looking for a loving home where he can be the center of attention and enjoy all the love he has to give!

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Or, how about these Mastiffs in cities near Denver, Colorado

These Mastiffs are available for adoption close to Denver, Colorado.
Photo of WARIO

WARIO

Mastiff

Male, 4 yrs 1 mo
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Wario`s foster parent says: Wario is a sweet and playful lover boy! Sweet, gentle, curious, energetic and handsome. He loves fetch. He is content to play on his own and wander about the yard but may do well with another dog as playmate as he has a lot of life in him and a love for other dogs. He has a good training foundation. I suspect he`d be a joyful and gentle addition to a family with children.* No small dogs or cats reccommended

Learn More

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Special Needs
Photo of Sabrina

Sabrina

Mastiff American Bulldog

Female, 6 yrs 9 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with kids, Not good with dogs, Good with cats, Needs special attention, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Sabrina, a gentle 6-year-old Mastiff mix who’s in need of a special forever home. Sabrina is living with mast cell tumors (MCT) due to cancer and is currently on medication to keep her as comfortable as possible. She requires a loving home that is prepared to offer her hospice care and a peaceful environment. Sabrina can be shy with new people and may give a warning growl or snap if approached when she’s not ready. However, once she builds trust, she becomes deeply affectionate and very attached to her people. She gets along well with mellow dogs and will thrive in a calm household where she can feel safe and loved. If you have a compassionate heart and are ready to provide a supportive and caring home for a special dog like Sabrina, you’ll find a loyal and loving companion in her.

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Photo of Maxine

Maxine

Mastiff

Female, 3 yrs
Boulder, CO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
🐾 _Meet Maxine!_ 😍 This gentle giant is a sweet 3-year-old, 66-pound Mastiff mix with a heart of gold. Pulled from a shelter's at her final notice, she's now ready to shower YOU with love 🐾💕. Playful with humans and pups alike, Maxine's favorite thing is snuggling up for hugs and smacks. As a volunteer's fave at the shelter, she'd brighten anyone's day. Ready to make you her person? 😁 Let's get Maxine home!

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Photo of Mylo

Mylo

Mastiff

Male, Senior
Highlands Ranch, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Mylo is an amazing dog, super friendly and easy going. Somewhat lazy but loves to play fetch from time to time or roam a field. He’s old and hard of hearing but great with all people and pets. He’s a tad overly friendly but likes to snooze most of the day. He still has lots of life to live and has been pretty pampered most of his life ! He Loves being near the kids and action of the day. Since relocating to a state with more sun he’s found a love for sunbathing. His one true love is open space and snowballs when available. He’s been an amazing part of our family but our current dynamic is not what’s best for him or our family sadly.

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Photo of Tenille

Tenille

Mastiff

Female, 5 yrs 3 mos
Aurora, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
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Photo of Judge

Judge

Mastiff

Male, 5 yrs
Boulder, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Judge Age about 4 100lbs Neutered Male Fluffy big-headed sweet lover-boy has officially arrived in Colorado, ready to start his journey to good health and fun! Judge came into the shelter a few weeks ago after being found severely injured. A neighbor reported that he had been attacked by another dog down the street. Despite everything he has been through, Judge has remained incredibly sweet and has such a gentle presence. He is a big, beautiful boy with so much love to give. **Great house manners, potty-trained **Loves car rides **Enjoys toys, food, and fun! **Leash trained; albeit his medical issues, that are currently being addressed limit his mobility, but he will be ready to explore when healed. **Very engaged, eager to please, will be so fun to train (treat motivated). **Currently living with female dog friend and is doing great, enjoys her company, shares toys, no food aggression whatsoever. **True to breed, he is a vocal observer, will likely need a home without shared walls. **Medium energy, can't wait to see him able to freely move about. This boy is ALL love. He loves pets, he leans into you for attention, he has phenomenal eye contact (very endearing), he wants to please. His coat is so soft and he has so much love to give his new family. No exposure to cats/kids, but will be working on that. He's just a big teddy bear! More details to come. ALL POSO DOGS COMES WITH 2 FREE DOG TRAINING SESSIONS Medical: - Xrays on leg and hips pending - Up to date on basic shots - Microchipped - Neuter pending - Heartworm test negative, tick disease test pending - Fecal testing pending

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These pups are in Denver, Colorado too!

Below are our newest added Mastiffs available for adoption in Denver, Colorado. To see more adoptable Mastiffs in Denver, Colorado, use the search tool below to enter specific criteria!
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Photo of BERZA

BERZA

St. Bernard

Female, 9 mos
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
HI, hi, hi!! I am Berza! I am a young, energetic kiddo who would love a home that`s okay with lots of fun and and fluff! I have an awesome time with playing all my shelter friends, and even sometimes playing with other dogs here! If you`re looking for a new fluffy friend to adventure with, come on down today!

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Photo of Zen

Zen

Neapolitan Mastiff Mastiff

Male, 6 yrs
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Needs experienced adopter, Spayed or Neutered, Shots are up-to-date,
Story
Zen is a 6-year-old male Neo Mastiff mix who’s as big-hearted as he is big in stature. Rescued from a shelter after his previous owners surrendered him for being “too big,” Zen is now on the hunt for his forever home where he can truly shine. Zen is a sweet, playful giant with a lot of energy for his breed. He’s very intelligent and learns quickly, making him a joy to train. However, Zen prefers to be the only dog in the home; he can get jealous and aggressive with other dogs, wanting all the attention for himself. When he's your one and only, he’s incredibly loving and will shower you with affection. Though he’s not reactive to other dogs on leash, Zen does best in a home without canine companions. He appreciates careful introductions to new people, especially those who approach unexpectedly. Zen’s ideal owner will be someone experienced with his breed and capable of continuing his training and socialization. If you’re ready to welcome a devoted and energetic companion into your life, Zen could be the perfect fit. He’s looking for a loving home where he can be the center of attention and enjoy all the love he has to give!

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Photo of Mortimer

Mortimer

St. Bernard Shepherd (Unknown Type)

Male, 6 yrs 1 mo
Denver, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hi there!  Mortimer here! The nice rescue people have asked me to tell you about myself, so here goes .... I am a world class squirrel defense expert. I have been told that i shouldn't lead wth that, but I think it's the most important, so there we go. I am also an expert at eating snacks :) aaaaaaand now they say they are taking over writing this .... Morti is around 5 years old and survived prostate cancer in 2021! The required surgery has made him a bit sensitive about his rear end when it comes to other dogs sniffing it, so he can be a bit dog selective. He does better with female dogs that respect his boundaries. He was not kidding about the squirrel defense expert bit - he has an ongoing feud with the neighborhood squirrels at his foster house. Morti can't live with cats (or any small animals really) as his prey drive is just too high. He would thrive in a home with a fenced yard and a family that can continue his structured daily walks. If you have a garden, he will "help" you in it. His foster mom solved this by giving him his own garden bed to till. Morti is house and crate trained, and does fine in the crate while his foster family is away from the house.

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Denver, Colorado.

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Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Arvada, CO Mastiff in Aurora, CO Mastiff in Boulder, CO Mastiff in Brighton, CO Mastiff in Broomfield, CO Mastiff in Castle Rock, CO Mastiff in Centennial, CO Mastiff in Cherry Hills Village, CO Mastiff in Commerce City, CO Mastiff in Edgewater, CO Mastiff in Englewood, CO Mastiff in Erie, CO Mastiff in Federal Heights, CO Mastiff in Firestone, CO Mastiff in Fort Lupton, CO Mastiff in Frederick, CO Mastiff in Golden, CO Mastiff in Greenwood Village, CO Mastiff in Lafayette, CO Mastiff in Lakewood, CO Mastiff in Littleton, CO Mastiff in Lone Tree, CO Mastiff in Longmont, CO Mastiff in Louisville, CO Mastiff in Northglenn, CO Mastiff in Parker, CO Mastiff in Sheridan, CO Mastiff in Superior, CO Mastiff in Thornton, CO Mastiff in Westminster, CO Mastiff in Wheat Ridge, CO

Related breeds in Denver, Colorado

Bullmastiffs in Denver, Colorado Neapolitan Mastiffs in Denver, Colorado Saint Bernards in Denver, Colorado

Mastiff shelters & rescues in Denver, Colorado

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Denver, Colorado. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

4.3 miles

Denver Animal Shelter

1241 W. Bayaud Ave, Denver, CO 80223

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

6 miles

Ace of Hearts Dog Rescue - CO Transport Stop

711 Walnut St, Boulder, CO 80203

Pet Types: dogs

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Rescue

15.9 miles

Big Dogs Huge Paws, Inc

PO Box 460699, Aurora, CO 80046

Pet Types: dogs

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Shelter

25.1 miles

Humane Society of Boulder Valley

2323 55th Street, Boulder, CO 80301

Pet Types: cats, dogs, small animals

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Rescue

25.1 miles

POSO Dog Rescue - Colorado

Boulder, CO 80301

Pet Types: dogs

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Shelter

31.6 miles

Soul Dog Rescue

1245 Factory Circle, Fort Lupton, CO 80621

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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