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Mastiff puppies and dogs in Denver, Colorado

Looking for a Mastiff puppy or dog in Denver, Colorado? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Denver, Colorado

These Mastiffs are available in Denver, Colorado.
Special Needs
No photo available for Sabrina

Sabrina

Mastiff American Bulldog

Female, 7 yrs 8 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Needs special attention, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Sabrina, a gentle 6-year-old Mastiff mix who’s in need of a special forever home. Sabrina is living with mast cell tumors (MCT) due to cancer and is currently on medication to keep her as comfortable as possible. She requires a loving home that is prepared to offer her hospice care and a peaceful environment. Sabrina can be shy with new people and may give a warning growl or snap if approached when she’s not ready. However, once she builds trust, she becomes deeply affectionate and very attached to her people. She gets along well with mellow dogs and will thrive in a calm household where she can feel safe and loved. If you have a compassionate heart and are ready to provide a supportive and caring home for a special dog like Sabrina, you’ll find a loyal and loving companion in her.

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Photo of Huckleberry

Huckleberry

Mastiff

Male, 1 yr 1 mo
Denver, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I’m Huckleberry, a 1 year  old male Mastiff mix. ********PLEASE READ BELOW PRIOR TO EMAILING IN**********If you are interested in adopting this dog or any other from our rescue, please go to https://www.hobocare.org/adopt to review our home requirements and fill out an application. Please do not email and ask for more information on how to adopt, all the information is already available online. The information you see here is all that is currently available about this dog. No boxers are adopted without a completed application and home check. Thank you! ##2619848##

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Photo of Zen

Zen

Neapolitan Mastiff Mastiff

Male, 7 yrs 8 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Needs experienced adopter, Spayed or Neutered, Shots are up-to-date,
Story
Zen is a 6-year-old male Neo Mastiff mix who’s as big-hearted as he is big in stature. Rescued from a shelter after his previous owners surrendered him for being “too big,” Zen is now on the hunt for his forever home where he can truly shine. Zen is a sweet, playful giant with a lot of energy for his breed. He’s very intelligent and learns quickly, making him a joy to train. However, Zen prefers to be the only dog in the home; he can get jealous and aggressive with other dogs, wanting all the attention for himself. When he's your one and only, he’s incredibly loving and will shower you with affection. Though he’s not reactive to other dogs on leash, Zen does best in a home without canine companions. He appreciates careful introductions to new people, especially those who approach unexpectedly. Zen’s ideal owner will be someone experienced with his breed and capable of continuing his training and socialization. If you’re ready to welcome a devoted and energetic companion into your life, Zen could be the perfect fit. He’s looking for a loving home where he can be the center of attention and enjoy all the love he has to give!

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Photo of Mishka

Mishka

Great Dane Mastiff

Female, 4 mos
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Shots are up-to-date,
Story
Introducing Mishka, the spirited and outgoing girl who's ready to steal your heart! With her confident personality, she’s always the life of the party, and her first encounter with a leash was nothing short of impressive—she simply picked it up and walked herself like a pro! Personality:Mishka is not just friendly; she's got a charming stubborn streak that makes her all the more adorable. This smart cookie is treat motivated, ensuring she'll be a quick learner as she picks up new skills. She’s a social butterfly, getting along famously with both people and her furry friends. Playtime:With her foster siblings, Mishka loves to engage in rough and tumble play, showing off her playful side. She's mastered the doggie door and is diligently working on her potty training, making great strides along the way. Leash Skills:Mishka’s leash skills are as cute as they come—she often prefers to walk herself! But don’t worry, her leash manners are improving, and she's learning to enjoy walks with her humans. Location:Currently fostered in Colorado Springs, Mishka is ready to find her forever home where she can continue to shine and bring joy to her new family! If you’re looking for a confident, playful, and loving companion, Mishka is the girl for you! Feel free to tweak any details to match your style! ##2748308##

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Photo of Bella

Bella

Great Dane Mastiff

Female, Young
Thornton, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Bella is an amazing dog, very friendly, sweet, and well trained. She loves walks and playing with toys. She loves the groomer and is very easy going. My husband has been diagnosed with cancer and we cannot take care of her the way she needs. We are looking for a good home with lots of love and a yard for her to enjoy!

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Or, how about these Mastiffs in cities near Denver, Colorado

These Mastiffs are available for adoption close to Denver, Colorado.
Special Needs
No photo available for Sabrina

Sabrina

Mastiff American Bulldog

Female, 7 yrs 8 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Needs special attention, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Sabrina, a gentle 6-year-old Mastiff mix who’s in need of a special forever home. Sabrina is living with mast cell tumors (MCT) due to cancer and is currently on medication to keep her as comfortable as possible. She requires a loving home that is prepared to offer her hospice care and a peaceful environment. Sabrina can be shy with new people and may give a warning growl or snap if approached when she’s not ready. However, once she builds trust, she becomes deeply affectionate and very attached to her people. She gets along well with mellow dogs and will thrive in a calm household where she can feel safe and loved. If you have a compassionate heart and are ready to provide a supportive and caring home for a special dog like Sabrina, you’ll find a loyal and loving companion in her.

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Photo of Huckleberry

Huckleberry

Mastiff

Male, 1 yr 1 mo
Denver, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I’m Huckleberry, a 1 year  old male Mastiff mix. ********PLEASE READ BELOW PRIOR TO EMAILING IN**********If you are interested in adopting this dog or any other from our rescue, please go to https://www.hobocare.org/adopt to review our home requirements and fill out an application. Please do not email and ask for more information on how to adopt, all the information is already available online. The information you see here is all that is currently available about this dog. No boxers are adopted without a completed application and home check. Thank you! ##2619848##

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Photo of Pluto

Pluto

Mastiff Rottweiler

Male, Adult
Littleton, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
Hi there, my name is Pluto! I am a big handsome guy with a fun demeanor. I am social, intelligent, and active. I am looking for a home where I will be treated just like a member of the family. I am going to need exercise, training, socialization, and affection. In return, I promise to bring you years of love, laughter, and loyalty. My adoption fee includes my neuter, a microchip, vaccines, and a fourteen day limited health guarantee through Redstone Animal Hospital! Come and visit me today! Primary Color: Red Secondary Color: White Weight: 90 Age: 3yrs 0mths 1wks

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Photo of Tenille

Tenille

Mastiff

Female, 4 yrs 11 mos
Aurora, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
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Photo of Fang

Fang

Mastiff Shepherd (Unknown Type)

Male, Adult
Parker, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Fang, a Mastiff mix with a heart of gold and the most intuitive soul you’ll ever encounter. Fang is the ultimate "gentle giant" who has reached his glory days and is looking for a couch to call his own. Fang is incredibly smart and acts as a loyal alert dog for the home. He is trained off and on lease and is naturally defensive of women. While he sounds intimidating to a stranger, he’s actually a total "scaredy-cat" who just wants to feel safe and loved. He surprisingly loves cats and enjoys a good game of tug-of-war. As he’s gotten older, his back legs get tired a bit faster, so he prefers short, leisurely strolls over long hikes. He’s a professional lounger who will happily nap on the sofa all day. He has been lovingly spoiled! His favorites include chicken and any kind of cheese. We’ve recently welcomed a new baby into our family, and we’ve realized we can no longer give Fang the focused attention and environment he deserves.

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Photo of Gumbo

Gumbo

Mastiff

Male, 1 yr 8 mos
Boulder, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Handsome Gumbo! This sweet boy is searching for a new home, could he be the right one for you? Gumbo loves pets and people, but can get overwhelmed at times and will benefit from an adopter that can support him when he needs it! He has also enjoyed the company of other dogs and might do well in a multi-dog home. At this time, HSBV will only rehome him to a family either without children or with children over the age of 10.

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These pups are in Denver, Colorado too!

Below are our newest added Mastiffs available for adoption in Denver, Colorado. To see more adoptable Mastiffs in Denver, Colorado, use the search tool below to enter specific criteria!
Photo of Zen

Zen

Neapolitan Mastiff Mastiff

Male, 7 yrs 8 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs, Needs experienced adopter, Spayed or Neutered, Shots are up-to-date,
Story
Zen is a 6-year-old male Neo Mastiff mix who’s as big-hearted as he is big in stature. Rescued from a shelter after his previous owners surrendered him for being “too big,” Zen is now on the hunt for his forever home where he can truly shine. Zen is a sweet, playful giant with a lot of energy for his breed. He’s very intelligent and learns quickly, making him a joy to train. However, Zen prefers to be the only dog in the home; he can get jealous and aggressive with other dogs, wanting all the attention for himself. When he's your one and only, he’s incredibly loving and will shower you with affection. Though he’s not reactive to other dogs on leash, Zen does best in a home without canine companions. He appreciates careful introductions to new people, especially those who approach unexpectedly. Zen’s ideal owner will be someone experienced with his breed and capable of continuing his training and socialization. If you’re ready to welcome a devoted and energetic companion into your life, Zen could be the perfect fit. He’s looking for a loving home where he can be the center of attention and enjoy all the love he has to give!

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Photo of Nina

Nina

St. Bernard

Female, 3 yrs
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Say hello to Nina! She came into rescue through no fault of her own when her family experienced medical issues and could no longer care for her. Nina has lived successfully with both children and other dogs and enjoys being part of a family. She is house-trained, crate-trained, and settles in nicely to home life. One of her favorite things is spending time with her people—whether that means lounging nearby or snuggling up for some affection. Like many dogs, Nina can be a little protective of especially high-value treats. She needs to eat separate so she can feel secure and doesn't feel like she needs to protect her dinner. The good news is that she communicates her boundaries appropriately and responds well when those signals are respected. Her adopters should be mindful of this behavior and continue to set her up for success through positive management and training. Nina is looking for a family who will appreciate her sweet nature, giant-breed charm, and love of companionship. If you're searching for a loyal best friend who enjoys cuddles as much as she enjoys being part of the family, Nina may be the perfect match. Apply to adopt on our website! https://cosaintrescue.org/adopt/

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Bonded Pair
Photo of Maggie

Maggie

St. Bernard

Female, 8 yrs
Denver, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Bonded pair Gus & Maggie come to after Maggie tore her CCL and their previous owner was unable to provide the level of care that she needed. Maggie is almost completely recovered from her TPLO surgery and these two are ready for their happy ever after! Gus can be protective of Maggie, so we recommend a home with no other dogs in it, but they get along just fine with their foster kitty brother! A home with few stairs and a fenced yard would be best for these two. Favorite activities include sunbathing, snowbathing, napping, watching squirrels, and getting belly rubs - in other words, the good life! Adoption application: https://cosaintrescue.org/adopt/

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Denver, Colorado.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Denver, Colorado

Bullmastiffs in Denver, Colorado Neapolitan Mastiffs in Denver, Colorado Saint Bernards in Denver, Colorado

Mastiff shelters & rescues in Denver, Colorado

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Denver, Colorado. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

6 miles

Ace of Hearts Dog Rescue - CO Transport Stop

711 Walnut St, Boulder, CO 80203

Pet Types: dogs

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Rescue

6.7 miles

Ho-Bo Care Boxer Rescue

Denver, CO 80209

Pet Types: dogs

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Shelter

7.7 miles

Humane Society of the South Platte Valley

2129 W Chenango Ave, Littleton, CO 80120

Pet Types: cats, birds, dogs, rabbits, small animals

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Rescue

15.9 miles

Big Dogs Huge Paws, Inc

PO Box 460699, Aurora, CO 80046

Pet Types: dogs

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Shelter

25.1 miles

Humane Society of Boulder Valley

2323 55th Street, Boulder, CO 80301

Pet Types: cats, dogs, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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