Mastiff Adoption in Colorado: Mastiff Puppies for Sale in Colorado

Adopt a Mastiff near you in Colorado

Below are our newest added Mastiffs available for adoption in Colorado. To see more adoptable Mastiffs in Colorado, use the search tool below to enter specific criteria!

NALA

Mastiff

Female, 6 mos

Denver, CO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

Came in with A430806Initially shy and can be vocal. Loves people and good at meeting other dogs.

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HARLEY

Mastiff

Female, 7 mos

Denver, CO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

Came in with A430805Shy and can be vocal. Warms up quickly and loves pets. Good at meeting new dogs

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Vishnu

Mastiff

Female, 4 yrs 6 mos

Windsor, CO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Good with cats,

Story

Meet Vishnu! Your Future Lovebug! 🐾❤️ Hello there! My name is Vishnu, and I am a stunning, brindle-coated English Mastiff looking for my forever family. I may be a "gentle giant" at 4 years old and roughly 155 pounds, but I promise I don't know my own size. I am the definition of a low-energy, loving companion. My favorite pastime is watching you walk from room to room, followed by a dramatic flop onto a comfy dog bed (or your couch, if allowed) for a long snooze. I am a calm, dignified, and loyal fellow who prefers a quiet home where I can be part of the family chaos, rather than locked away. I’m really a softie who wants to meet new friends once I know I'm safe. I live for gentle pets and scratches behind my ears. I am known to "lean" on my favorite humans—it's my way of showing I trust you completely and offering a big, wrinkly hug. While I’m a bit of a couch potato, I do love a slow, sniffy walk around the neighborhood to during the day. I would do best in a home with kids aged [e.g., 10+]—because I am big, I might accidentally knock over smaller, wobblier children.I am good with other dogs with a proper introduction and I can happily say I’m making friends with my foster feline-sibling. I need a family who has space for me and is ready for the "drool factor”. Previous experience with giant breeds is a plus, but not required. I am currently up to date on all my shots, spayed, and eager to please. If you are looking for a loyal, calm, and affectionate best friend to share your home, couch, and heart with, please apply to adopt me!

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Barnaby

Mastiff

Male, 3 yrs

Mead, CO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, House-trained,

Story

Meet your new oversized shadow with a heart of gold 💛 This 4-5 year-old English Mastiff is basically a real-life version of The Beast—big, lovable, and way less intimidating once you get to know him. At a petite 180 lbs, he firmly believes he’s a lap dog. He does great with both kids and adults. He loves to lean into his pets (all 180 pounds of him), and if you dare to stop, he’ll gently place a paw on you as a polite reminder to keep going. He’s a social guy who gets along well with dogs of all sizes, from tiny sidekicks to fellow giants. And while he may look like he could run a marathon, he actually tires out pretty quickly so expect short bursts of play followed by legendary naps. He’s an enthusiastic passenger for any and all car rides, too! A few bonus features: Drools like a champion (seriously, keep a towel handy) Gives world-class cuddles Doubles as a weighted blanket If you’re looking for a gentle giant who will adore your family, charm your friends, and leave a little drool trail of love wherever he goes, this is your guy. Barnaby is being fostered in Broomfield, Colorado. *We require all adopters to come to Colorado to adopt. *We do not transport dogs.* You can view this wonderful dog at https://www.milehighcanine.org/post/dogs/barnaby/. You can apply for our wonderful dogs at https://www.milehighcanine.org/adopt/adoption-application/.

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Special Needs

Duke

Mastiff

Male, 1 yr

Pueblo, CO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Needs special attention, Needs experienced adopter, House-trained,

Story

🐾 Meet Mamaduke “Duke” 🐾 Duke’s story is one of resilience, love, and second chances. 💔➡️❤️ At just 6 weeks old, Duke and his two siblings were found tied to a pole—in 10-degree weather—while their mama was tied to another, unable to reach them to feed or comfort them. Despite such a heartbreaking and cruel start to life, Duke has grown into a strong, loving, and loyal boy who is ready to find his forever home. Now 1 year old, Duke is a Mastiff mix with a big heart to match his size. He loves going for walks and enjoys being active, but he also has a gentle, affectionate side that shines once he feels safe. Duke does have a minor eye condition where his eyes may occasionally roll back. He can see, but his peripheral vision is limited, so he sometimes needs a little extra patience and understanding while navigating new environments. Because of this, Duke would do best with someone who is calm, kind, and willing to give him the time he needs to build trust. Duke is currently in foster, who's time is limited. Please reach out to us with any questions. 🐕 Dog-Friendly: Yes, with slow introductions 💪 Strong Walker: Will benefit from continued leash training ❤️ Personality: Loyal, loving, resilient Duke was adopted as a young puppy, but sadly his owner recently passed away, and he has found himself back with us through no fault of his own. This sweet boy has already experienced loss twice in his short life—he deserves a home that will be forever. ✨ Ideal Home: Patient and understanding adopter Someone comfortable with a large, strong dog A calm environment where he can feel secure Duke isn’t just looking for a home… he’s looking for his person. Someone who will see past his imperfections and recognize the incredible, loving companion he truly is. 💛 If you’re looking for a loyal best friend with a powerful story and an even bigger heart, Duke is your guy.

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Fang

Mastiff/Shepherd (Unknown Type)

Male, Adult

Parker, CO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with cats, House-trained,

Story

Meet Fang, a Mastiff mix with a heart of gold and the most intuitive soul you’ll ever encounter. Fang is the ultimate "gentle giant" who has reached his glory days and is looking for a couch to call his own. Fang is incredibly smart and acts as a loyal alert dog for the home. He is trained off and on lease and is naturally defensive of women. While he sounds intimidating to a stranger, he’s actually a total "scaredy-cat" who just wants to feel safe and loved. He surprisingly loves cats and enjoys a good game of tug-of-war. As he’s gotten older, his back legs get tired a bit faster, so he prefers short, leisurely strolls over long hikes. He’s a professional lounger who will happily nap on the sofa all day. He has been lovingly spoiled! His favorites include chicken and any kind of cheese. We’ve recently welcomed a new baby into our family, and we’ve realized we can no longer give Fang the focused attention and environment he deserves.

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Mastiff puppies and dogs in Colorado

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Below are our newest added Mastiffs available for adoption in Colorado. To see more adoptable Mastiffs in Colorado, use the search tool below to enter specific criteria!

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Mastiff puppies and dogs in Colorado

Jump to:

Adopt a Mastiff near you in Colorado

Below are our newest added Mastiffs available for adoption in Colorado. To see more adoptable Mastiffs in Colorado, use the search tool below to enter specific criteria!

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in Colorado cities

Mastiff shelters & rescues in Colorado

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog ?

Mastiff information

Mastiff basics