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Mastiff puppies and dogs in Lafayette, Colorado

Looking for a Mastiff puppy or dog in Lafayette, Colorado? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Lafayette, Colorado Other pups in Lafayette, Colorado Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Lafayette, Colorado Mastiff shelters and rescues in Lafayette, Colorado Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Lafayette, Colorado

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Lafayette, Colorado

These Mastiffs are available for adoption close to Lafayette, Colorado.
We'll also keep you updated on SCOOBY-DOO's adoption status with email updates.
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SCOOBY-DOO

Mastiff Husky

Male, Young
Federal Heights, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Hello my Name is Scooby-Doo I'm 2 Yrs Old I'm a Great and Very Loving Dog, However I'm a litte Hard Headed And Sometimes Times Stubborn. I'm Very Playfully, I Frequently Go to the Westminster Open Space Dog Park near Stanley Lake, I run and play with all the other Dogs making Friends and having a Wonderful time, Never Showing any Aggression towards the other Dogs or the other people there, I'm Well Tempted. My Eyes are Ghost Blue, I get that From My Husky Father and My Mother is Mastiff. I'm looking For Great new Home with tons of Love, And a Big Back yard to run And Play, All my Vaccination Are Current Threw The Spur Clinic, I Am Also Fixed and House Trained. PLEASE Consider Being My New Family and Home , Thank you

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We'll also keep you updated on Sully's adoption status with email updates.
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Sully

Mastiff Boxer

Male, 1 yr
Mead, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
We are so happy to introduce you to Sully! Sully is an 87 ish lbs, 1 year old, happy boy! We suspect he’s a Mastiff/Boxer mix. Sully is so friendly and boisterous. He loves to run and play with his canine companions. When it’s time to chill, he will calmly lay on a dog bed and chew his toys. Sully knows a few commands: sit, down, shake, drop it, and wait. He’s so polite (but sometimes he gets really happy and jumps up on you to say “hi”) and affectionate — please don’t stop petting him, that’s just rude. Sully is house trained, crate trained, walks well on a leash, and loves a good game of fetch. If you’re missing an over-sized, playful, teddy bear, he’s your boy! Sully is being fostered in Mead, Colorado. *We require all adopters to come to Colorado to adopt. *We do not transport dogs.* You can view this wonderful dog at https://www.milehighcanine.org/post/dogs/sully/. You can apply for our wonderful dogs at https://www.milehighcanine.org/adopt/adoption-application/.

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We'll also keep you updated on Sabrina's adoption status with email updates.
Special Needs
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Sabrina

Mastiff American Bulldog

Female, 7 yrs 4 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Needs special attention, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Sabrina, a gentle 6-year-old Mastiff mix who’s in need of a special forever home. Sabrina is living with mast cell tumors (MCT) due to cancer and is currently on medication to keep her as comfortable as possible. She requires a loving home that is prepared to offer her hospice care and a peaceful environment. Sabrina can be shy with new people and may give a warning growl or snap if approached when she’s not ready. However, once she builds trust, she becomes deeply affectionate and very attached to her people. She gets along well with mellow dogs and will thrive in a calm household where she can feel safe and loved. If you have a compassionate heart and are ready to provide a supportive and caring home for a special dog like Sabrina, you’ll find a loyal and loving companion in her.

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We'll also keep you updated on NANI's adoption status with email updates.
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NANI

Mastiff

Female, Young
Denver, CO
Size
(when grown) -
Details
Spayed or Neutered,
Story
What a gorgeous sweetheart! Nani is so great! She's very sweet, gentle, friendly, fun and playful, and she has a calm, thoughtful personality. She's all about pets, cuddles, tummy rubs, and leisurely, luxurious walks with lots of sniffing on Nani-time! She just really enjoys being outdoors -- taking in all the sights, smells, and sounds, and stopping to smell the roses. Nani also loves treats and recently dried lamb and tripe was a hit. But most of all, she loves you and being your loving companion. Nani is housetrained and while she may be shy when meeting some men for the first time, she opens her heart when she knows you're a trusted friend. Only because of her size, kids age 10+ and no cats are best in a home with no shared walls. Nani is really an incredible, special girl, come fall in love!February 18, 2026, 6:24 pm

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We'll also keep you updated on HUDSON's adoption status with email updates.
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HUDSON

Mastiff

Male, Adult
Denver, CO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
February 19, 2026, 5:43 pm

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We'll also keep you updated on Tenille's adoption status with email updates.
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Tenille

Mastiff

Female, 4 yrs 7 mos
Aurora, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
-

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Lafayette, Colorado.

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Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Arvada, CO Mastiff in Aurora, CO Mastiff in Berthoud, CO Mastiff in Boulder, CO Mastiff in Brighton, CO Mastiff in Broomfield, CO Mastiff in Centennial, CO Mastiff in Cherry Hills Village, CO Mastiff in Commerce City, CO Mastiff in Denver, CO Mastiff in Edgewater, CO Mastiff in Englewood, CO Mastiff in Erie, CO Mastiff in Estes Park, CO Mastiff in Evans, CO Mastiff in Federal Heights, CO Mastiff in Firestone, CO Mastiff in Fort Lupton, CO Mastiff in Frederick, CO Mastiff in Golden, CO Mastiff in Greeley, CO Mastiff in Greenwood Village, CO Mastiff in Johnstown, CO Mastiff in Lakewood, CO Mastiff in Littleton, CO Mastiff in Lone Tree, CO Mastiff in Longmont, CO Mastiff in Louisville, CO Mastiff in Loveland, CO Mastiff in Milliken, CO Mastiff in Northglenn, CO Mastiff in Sheridan, CO Mastiff in Superior, CO Mastiff in Thornton, CO Mastiff in Westminster, CO Mastiff in Wheat Ridge, CO Mastiff in Windsor, CO

Related breeds in Lafayette, Colorado

Bullmastiffs in Lafayette, Colorado Neapolitan Mastiffs in Lafayette, Colorado Saint Bernards in Lafayette, Colorado

Mastiff shelters & rescues in Lafayette, Colorado

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Lafayette, Colorado. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

17.3 miles

Mile High Canine Rescue, Inc.

Mead, CO 80542

Pet Types: dogs

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Rescue

19.6 miles

Ace of Hearts Dog Rescue - CO Transport Stop

711 Walnut St, Boulder, CO 80203

Pet Types: dogs

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Shelter

25.1 miles

Humane Colorado

2080 S Quebec St, Denver, CO 80231

Pet Types: cats, dogs, horses, rabbits, small animals

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Rescue

30.3 miles

Big Dogs Huge Paws, Inc

PO Box 460699, Aurora, CO 80046

Pet Types: dogs

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Rescue

37.7 miles

All Aboard Animal Rescue

Fort Collins, CO 80526

Pet Types: cats, dogs

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Shelter

41.5 miles

Grand County Animal Shelter

3475 CR 57, Granby, CO 80446

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

43.9 miles

Until They're Home

Fort Collins, CO 80524

Pet Types: cats, dogs, rabbits, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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