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Mastiff puppies and dogs in Frederick, Colorado

Looking for a Mastiff puppy or dog in Frederick, Colorado? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Frederick, Colorado Other pups in Frederick, Colorado Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Frederick, Colorado Mastiff shelters and rescues in Frederick, Colorado Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Frederick, Colorado

These Mastiffs are available in Frederick, Colorado.
Photo of Nala

Nala

Mastiff Husky

Female, Adult
Erie, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
We have had Nala since she was 8weeks old! She is now 5 will be 6 December 22nd! She is a cuddle bug for sure and loves to play! shes very smart and learns quickly. She is kennel trained, house trained and knows basic commands. She loves her paw held. She will literally be your best friend. She needs an active loving family. I have developed an allergy to her fur and while i have been able to manage it pretty well our work situation is also changing within the next few weeks and i dont want her home alone or kenneled for the majority of the day. She deserves better than that. She is up to date on shots and goes to her annual well checks. Shes also been to doggy boarding and does great. Shes great with other dogs big or small and loves kids. she loves anyone that loves her honestly. She is not spayed but probably should be.

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Or, how about these Mastiffs in cities near Frederick, Colorado

These Mastiffs are available for adoption close to Frederick, Colorado.
Photo of Nala

Nala

Mastiff Husky

Female, Adult
Erie, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
We have had Nala since she was 8weeks old! She is now 5 will be 6 December 22nd! She is a cuddle bug for sure and loves to play! shes very smart and learns quickly. She is kennel trained, house trained and knows basic commands. She loves her paw held. She will literally be your best friend. She needs an active loving family. I have developed an allergy to her fur and while i have been able to manage it pretty well our work situation is also changing within the next few weeks and i dont want her home alone or kenneled for the majority of the day. She deserves better than that. She is up to date on shots and goes to her annual well checks. Shes also been to doggy boarding and does great. Shes great with other dogs big or small and loves kids. she loves anyone that loves her honestly. She is not spayed but probably should be.

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Photo of Antonella 2

Antonella 2

Mastiff Australian Cattle Dog

Female, 2 yrs 7 mos
Fort Lupton, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered, Shots are up-to-date,
Story
The biggest, sweetest girl! Good with kids and other dogs!

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Photo of Daphne

Daphne

Mastiff

Female, Young
Greeley, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Not good with cats, Spayed or Neutered, Shots are up-to-date,
Story
Daphne, Mastiff mix, 1.5 yrs. 105 lbs. Daphne is friendly and calm. She’s good with other dogs and wants to play with them. No cats. She was found on a country road with a bowl and a bag of dog food. We want a home for her with someone home most of the time and another younger dog to hang out with. Call Cindy 970-353-1385

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Photo of Uma

Uma

Mastiff

Female, Senior
Greeley, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Uma is an approximately 9-year-old Mastiff mix with the gentlest heart. She is a giant cuddle bug who believes she is a lap dog and loves nothing more than being close to her people. Uma is sweet, calm, and incredibly affectionate.Uma was adopted as a rescue, and her early life was difficult. Because of past trauma, she can become reactive on walks, but with a proper harness and mindful handling she does very well.She has lived peacefully with dogs, cats, and children of all ages, including babies, whom she absolutely adores. Slow introductions to new animals may help her feel safe, but she has never harmed any people or animals.Mastiffs have relatively short lifespans, and our greatest hope is to find Uma a loving home where she can spend her senior years surrounded by comfort, affection, and family.Uma is currently in Centennial, CO and is ready to meet you!

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Photo of Tank

Tank

Mastiff Rottweiler

Male, Puppy
Denver, CO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Shots are up-to-date,
Story
DOB: August or September 2025 Intact because waiting until full grown Personality: He is a really goofy, loving dog. The kind that will melt into you. He likes kids and other dogs. He has been to doggy daycare and boarding without issues. Medium/high puppy energy. He’s food motivated and he does well with training exercises. Likes to hike, go for walks, and play at the dog park. Can play too aggressively for some small dogs. On the purina hydrolyzed diet since June 10. Has had chronic diarrhea on chicken, lamb, and salmon protein based foods. New diet stopped diarrhea. Yay! Dog friendly vegetables and fruit for treats. Reason for Rehoming: I travel 50% of the time for a new job. During my travel periods it’s been hard to train and provide the right activity level. My adult dog, a 5 year old lab, isn’t getting the attention he needs because of the pup as well.

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Special Needs
No photo available for Sabrina

Sabrina

Mastiff American Bulldog

Female, 7 yrs 9 mos
Boulder, CO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Needs special attention, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Sabrina, a gentle 6-year-old Mastiff mix who’s in need of a special forever home. Sabrina is living with mast cell tumors (MCT) due to cancer and is currently on medication to keep her as comfortable as possible. She requires a loving home that is prepared to offer her hospice care and a peaceful environment. Sabrina can be shy with new people and may give a warning growl or snap if approached when she’s not ready. However, once she builds trust, she becomes deeply affectionate and very attached to her people. She gets along well with mellow dogs and will thrive in a calm household where she can feel safe and loved. If you have a compassionate heart and are ready to provide a supportive and caring home for a special dog like Sabrina, you’ll find a loyal and loving companion in her.

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Frederick, Colorado.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Frederick, Colorado

Bullmastiffs in Frederick, Colorado Neapolitan Mastiffs in Frederick, Colorado Saint Bernards in Frederick, Colorado

Mastiff shelters & rescues in Frederick, Colorado

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Frederick, Colorado. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

6.9 miles

Soul Dog Rescue

1245 Factory Circle, Fort Lupton, CO 80621

Pet Types: cats, dogs

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Rescue

23.1 miles

Homeward Bound Rescue of Colorado

Greeley, CO 80634

Pet Types: dogs

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Rescue

25.6 miles

Ace of Hearts Dog Rescue - CO Transport Stop

711 Walnut St, Boulder, CO 80203

Pet Types: dogs

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Shelter

26 miles

Polk County Humane Society (in Missouri) - Colorado Transport

3511 N Salida Court, Aurora, CO 80011

Pet Types: cats, dogs

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Rescue

27.4 miles

Ho-Bo Care Boxer Rescue

Denver, CO 80209

Pet Types: dogs

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Rescue

32.1 miles

All Aboard Animal Rescue

Fort Collins, CO 80526

Pet Types: cats, dogs

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Rescue

33.5 miles

Big Dogs Huge Paws, Inc

PO Box 460699, Aurora, CO 80046

Pet Types: dogs

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Shelter

34.7 miles

Humane Society of the South Platte Valley

2129 W Chenango Ave, Littleton, CO 80120

Pet Types: cats, birds, dogs, rabbits, small animals

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Rescue

36.7 miles

L.O.L.A.'S Rescue

6005 S. Taft Way, Littleton, CO 80127

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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