Mastiff Adoption in Union, MO: Mastiff Puppies for Sale in Union, MO

Adopt a Mastiff near you in Union, Missouri

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Union, Missouri

These Mastiffs are available for adoption close to Union, Missouri.

Murphy aka WC Babe Pup-Berte

Mastiff Terrier (Unknown Type, Medium)

Male, Adult

Warrenton, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, Spayed or Neutered, Shots are up-to-date,

Story

Have you ever seen a better looking sweet and fun guy? I am just a little guy looking for my forever home to grow up in. Come meet me please. I would love a home of my own. July 10, 2026, 11:57 am

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Margie Mae

Mastiff Boxer

Female, Adult

Cottleville, MO

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with kids, Good with dogs, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

I am need of help rehoming Margie Mae. Long story, short version. I was awarded her in a divorce and have tried to keep her but I have no back yard. I mention this because we have to take her potty out front and she wants to defend our house and because of this she has gone after our neighbor’s dog. It’s weird because this is the only place that she acts like this. She adores all people and all dogs. She is fine at the dog park. Other places. Anywhere. Just not in front of our house. We’ve tried training and she is on medication for the anxiety. She is fixed and up to date with her shots. She is almost 6. She is ridiculously sweet 99% of the time. Her tail is always wagging. Just really want to find her a place where she can be calm and comfortable. She is a good girl. Happy to answer any questions. I am in Cottleville, MO Thank you in advance. $50 Rehoming fee. She just needs a good home.

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Freya

Mastiff

Female, 4 yrs 1 mo

St. Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,

Story

Hi, I'm Freya! I'm a sweet mama and came with my 9 puppies. I'm a very good girl. I'm said to have had a few litters in the past and I'm ready to put motherhood behind me and have a little time for myself. Won't you spend it with me? If you're interested in adopting me, please fill out an application at www.polkcountyhumanesociety.org/adopt. You can also reserve an appointment to meet me. Some pets are in foster homes or may already have visits scheduled, so appointments help ensure I’ll be available. Polk County Humane Society is located in Bolivar, Missouri, and we welcome adopters from any state. We have access to a transport to Aurora, CO. Other out of state adopters either travel to Missouri or arrange & pay for air transport. Virtual meet and greets are available on the appointment request. ##2755149##

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Luke AG

Mastiff American Pit Bull Terrier

Male, 4 yrs 4 mos

St Louis, MO

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,

Story

Hi, I’m Luke, and I’m a big, lovable boy tipping the scales at just over 100 lbs! Don’t let my size fool you—I’m a happy, easygoing pup who just wants to play, explore, and cuddle. I’m all about the good things in life: squeaky toys, water play, long walks, and best of all—snuggle time on the couch. I’m a pro at giving hugs (though I’m working on not jumping up too hard to give them—oops!). I get along great with other dogs and kids, but because of my size and enthusiasm, I’d do best with older children who won’t get accidentally knocked over during playtime. I’m crate trained, housebroken, and walk nicely on a leash—unless there’s a squirrel… then it’s game on! I do have a slight prey drive, so a little guidance goes a long way. If you’re looking for a big-hearted, playful companion to fill your home with love (and maybe take up some space on your couch), I’m your guy. Let’s make forever happen! 🐾 Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)

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Finn AKA Gage JuM

Mastiff Shepherd (Unknown Type)

Male, 7 yrs 4 mos

St Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, Spayed or Neutered,

Story

Finn may look like a rockstar with his striking Mastiff–Shepherd good looks, but at heart, he’s a big, soft lovebug. Weighing in at about 60 pounds, Finn has grown into a handsome boy with a beautiful gray and tan coat, soulful eyes, and an even bigger personality. Despite his star-quality appearance, Finn is more of a laid-back, easygoing guy—think Eeyore vibes, but with engines revved and ready to love. From the moment he wakes up, he’s prepared to shower his people with affection… and trust us, it’s A LOT of love! Finn does well with other dogs and does need a slow, proper introductions to new friends—both two-legged and four-legged. Once he knows you, he loves you deeply. He’s happiest when he has a buddy (human or canine) to share his world with. Affection is Finn’s specialty. When someone comes to greet him, he lights up, runs over with enthusiasm, and hands out slobbery kisses and big hugs like they’re backstage passes. His joy is genuine, his heart is huge, and he’s always thrilled to see his people. If you’re looking for a big, lovable, slightly goofy rockstar who will adore you endlessly, Finn is ready to take center stage in your heart. Local adoption only $200 (in TX)

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HIPPIE

Mastiff

Female, 1 yr 3 mos

St. Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Spayed or Neutered,

Story

Hippie is a social, sweet girl who loves being wherever her people are. She enjoys plenty of pets, walks beautifully on the leash, and is always happy to stay close by for companionship. With her loving personality, Hippie is the perfect partner!

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Mastiff puppies and dogs in Union, Missouri

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Adopt a Mastiff near you in Union, Missouri

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Union, Missouri

These Mastiffs are available for adoption close to Union, Missouri.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Union, Missouri

Mastiff shelters & rescues in Union, Missouri

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics