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Mastiff puppies and dogs in Missouri

Looking for a Mastiff puppy or dog in Missouri? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff in Missouri Search for a Mastiff puppy or dog Mastiff puppies and dogs in Missouri cities Mastiff shelters and rescues in Missouri Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Missouri

Below are our newest added Mastiffs available for adoption in Missouri. To see more adoptable Mastiffs in Missouri, use the search tool below to enter specific criteria!
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HIPPIE

Mastiff

Female, 1 yr 2 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Hippie is a social, sweet girl who loves being wherever her people are. She enjoys plenty of pets, walks beautifully on the leash, and is always happy to stay close by for companionship. With her loving personality, Hippie is the perfect partner

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Phoebe

Mastiff

Female, 8 yrs 3 mos
Reeds Spring, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Needs experienced adopter,
Story
DOB: 3/1/2018 Breed: Mastiff Personality:  Phoebe is a beautiful Mastiff girl who is learning that people can be kind. We believe she may have been used for breeding before finding her way to us, and it is clear life has not always been easy for her. ​ Phoebe came to the shelter after being left outside in a kennel with nothing but a bag of food. Since arriving, she has been slowly learning what safety and care look like. New people can make her nervous, and being kenneled around other dogs is stressful for her. ​ She was not given much socialization early in life, so new experiences can feel overwhelming. Even so, Phoebe is making progress. Little by little, she is starting to let her guard down and show the sweet dog underneath. She will need someone patient who understands that trust takes time. Experience with Mastiffs or other giant breeds would be a big plus for this special girl. ​ Phoebe has been through more than any dog should, and she deserves to know what it feels like to be safe, loved, and finally home. If you think you might be the person to give her that chance, please come meet her.

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Photo of Selmar

Selmar

Mastiff/Mixed Breed (Medium)

Male, 2 yrs
St. Louis, MO
Size
(when grown) -
Details
-
Story
-

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Photo of Murphy aka WC Babe Pup-Berte

Murphy aka WC Babe Pup-Berte

Mastiff/Terrier (Unknown Type, Medium)

Male, Adult
Warrenton, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats,
Story
Have you ever seen a better looking sweet and fun guy? I am just a little guy looking for my forever home to grow up in. Come meet me please. I would love a home of my own. June 14, 2026, 1:13 am

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Photo of Rose

Rose

Mastiff/Great Dane

Female, 1 mo
Branson, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
26-D-062

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Photo of Ellie

Ellie

Mastiff/Great Dane

Female, 1 mo
Branson, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
26-D-063

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Missouri.

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Mastiff puppies and dogs in Missouri cities

Mastiff Puppies near me Mastiff in Arnold Mastiff in Aurora Mastiff in Ballwin Mastiff in Belton Mastiff in Berkeley Mastiff in Black Jack Mastiff in Blue Springs Mastiff in Bolivar Mastiff in Bonne Terre Mastiff in Boonville Mastiff in Bowling Green Mastiff in Branson Mastiff in Breckenridge Hills Mastiff in Brentwood Mastiff in Bridgeton Mastiff in Brookfield Mastiff in Butler Mastiff in Cameron Mastiff in Cape Girardeau Mastiff in Carl Junction Mastiff in Carthage Mastiff in Caruthersville Mastiff in Charleston Mastiff in Chesterfield Mastiff in Chillicothe Mastiff in Clayton Mastiff in Clinton Mastiff in Columbia Mastiff in Creve Coeur Mastiff in Crystal City Mastiff in Dardenne Prairie Mastiff in Desloge Mastiff in De Soto Mastiff in Des Peres Mastiff in Dexter Mastiff in Eldon Mastiff in Ellisville Mastiff in Eureka Mastiff in Excelsior Springs Mastiff in Farmington Mastiff in Ferguson Mastiff in Festus Mastiff in Florissant Mastiff in Fulton Mastiff in Gladstone Mastiff in Grain Valley Mastiff in Grandview Mastiff in Greenwood Mastiff in Hannibal Mastiff in Harrisonville Mastiff in Hazelwood Mastiff in Higginsville Mastiff in Independence Mastiff in Jackson Mastiff in Jefferson City Mastiff in Jennings Mastiff in Joplin Mastiff in Kansas City Mastiff in Kearney Mastiff in Kennett Mastiff in Kirksville Mastiff in Kirkwood Mastiff in Lake St Louis Mastiff in Lamar Mastiff in Lebanon Mastiff in Lees Summit Mastiff in Lexington Mastiff in Liberty Mastiff in Macon Mastiff in Malden Mastiff in Manchester Mastiff in Maplewood Mastiff in Marshall Mastiff in Marshfield Mastiff in Maryland Heights Mastiff in Maryville Mastiff in Mexico Mastiff in Moberly Mastiff in Monett Mastiff in Mountain Grove Mastiff in Mount Vernon Mastiff in Neosho Mastiff in Nevada Mastiff in Nixa Mastiff in Normandy Mastiff in North Kansas City Mastiff in Oak Grove Mastiff in Odessa Mastiff in O Fallon Mastiff in Olivette Mastiff in Osage Beach Mastiff in Overland Mastiff in Ozark Mastiff in Pacific Mastiff in Park Hills Mastiff in Parkville Mastiff in Peculiar Mastiff in Perryville Mastiff in Pevely Mastiff in Platte City Mastiff in Pleasant Hill Mastiff in Poplar Bluff Mastiff in Raymore Mastiff in Raytown Mastiff in Republic Mastiff in Richmond Mastiff in Richmond Heights Mastiff in Rolla Mastiff in Saint Ann Mastiff in Saint Charles Mastiff in Saint Clair Mastiff in Saint Joseph Mastiff in Saint Louis Mastiff in Saint Peters Mastiff in Salem Mastiff in Savannah Mastiff in Scott City Mastiff in Sedalia Mastiff in Sikeston Mastiff in Smithville Mastiff in Springfield Mastiff in Ste Genevieve Mastiff in Sullivan Mastiff in Town and Country Mastiff in Trenton Mastiff in Troy Mastiff in Union Mastiff in University City Mastiff in Valley Park Mastiff in Vandalia Mastiff in Warrensburg Mastiff in Warrenton Mastiff in Washington Mastiff in Webb City Mastiff in Webster Groves Mastiff in Weldon Spring Mastiff in Wentzville Mastiff in West Plains Mastiff in Wildwood

Mastiff shelters & rescues in Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Missouri. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Ozark Haven Rescue

Cabool , MO 65689

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

Cuba Mo Animal Control

224 Enterprise Drive, Cuba , MO 65453

Pet Types: cats, dogs

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Shelter

Branson Humane Society

2837 Shepherd of the Hills Expressway, Suite C, Branson , MO 65616

Pet Types: cats, dogs, rabbits, small animals

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Shelter

Tri-Lakes Humane Society

102 Washboard Hollow Road, Reeds Spring , MO 65737

Pet Types: cats, dogs

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Shelter

Old Drum Animal Shelter

37 SW 101 Rd, Warrensburg , MO 64093

Pet Types: cats, birds, dogs, rabbits, small animals

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Shelter

Carthage Humane Society Inc

13860 Dog Kennel Rd., Carthage , MO 64836

Pet Types: cats, dogs, rabbits

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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