Mastiff Adoption in De Soto, MO: Mastiff Puppies for Sale in De Soto, MO

Adopt a Mastiff near you in De Soto, Missouri

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near De Soto, Missouri

These Mastiffs are available for adoption close to De Soto, Missouri.

Bellatrix aka "Willow Eliza"

Mastiff

Female, 8 yrs 1 mo

St. Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Spayed or Neutered,

Story

Bella is big and beautiful with a personality to match. This six-year-old mastiff mix girl adores people, snuggles, pets, and attention. She is spayed and up-to-date on all her medical care and is heartworm-negative. Bella is a big girl, approximately 65 pounds, so while she is very good with people, she would be best with older kids who can keep up with her size. She is house-trained, and a fenced yard would be best since Bella is a large dog and likes to play. Bella likes her people so much she doesn't want to share and would do best as the only dog in her home. To meet Bella, visit istodaymydayrescue.org to fill out an application. Her adoption fee is $100.

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Gus

Mastiff Mixed Breed (Large)

Male, Adult

St. Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Meet Gus! Gus is a charming 3-year-old mastiff mix with a heart as big as his paws. This gentle giant is friendly, outgoing, and absolutely loves people. He gets along wonderfully with other dogs and kids—just be prepared for a little “bull in a china shop” energy when he gets excited! Gus is house-trained, kennel-trained, and making great progress with his leash skills. He’s also an excellent car buddy, happy to settle in and enjoy the ride. If you’re looking for a lovable, goofy companion who brings joy wherever he goes, Gus might just be your perfect match! https://www.shelterluv.com/matchme/adopt/NAF/Dog

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Sage

Mastiff

Female, Adult

Saint Louis, MO

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Hi! Sage is what I believe is an iltalian mastiff mix of some sort. Her exact breed is unknown. Her birthday is 2/24/23. She has never resided in a shelter. She was fostered for 2 months through the Stray Reacue, then adopted by me. I am looking to rehome her solely because she is a very social dog who thrives in a home with multiple humans/dogs. Given my sudden life change, I am no longer able to provide that for her. I have noticed her a bit less happy in a home with just myself and her. Please reach out with any additional questions/concerns!

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Compton

Mastiff Labrador Retriever

Male, 2 yrs 11 mos

St. Louis, MO

Size

(when grown) -

Details

Good with dogs, Not good with cats, House-trained, Spayed or Neutered,

Story

Compton is a big-hearted, laid-back pup who’s been through a lot and is now searching for the perfect home to call his own. Found abandoned in a park back in January with a collar and lead still attached, it’s clear that he was once someone’s pet—but now he’s looking for a family that truly understands him. Shelter life has been stressful for him, making his search for a loving home even more urgent. While he’s an absolute sweetheart, he thrives best in a calm environment without young kids, as their energy and unpredictability seem to overwhelm him. Otherwise, Compton is truly the bestest boy! This gentle lug is fully crate-trained—though a little hesitant to go in at first, a toy will convince him, and once inside, he settles quietly. He’s also potty trained and will patiently sit by the door to let you know when it’s time to go out. A dream passenger in the car, Compton enjoys gazing out the window or relaxing for the ride. He walks beautifully on a loose leash and has done well with the few dogs he’s met, suggesting he could be a great canine companion with proper introductions. At his core, Compton is just a big teddy bear who deserves all the love in a peaceful, understanding home. If you’re looking for a loyal and affectionate best friend, Compton is ready to be your perfect companion.

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Mr. Bojangles

Mastiff Mixed Breed (Large)

Male, 3 yrs 4 mos

St. Louis, MO

Size

(when grown) -

Details

Spayed or Neutered,

Story

Meet Mr. Bojangles, a distinguished male dog around three years old, who brings both class and a dash of drama to the table! He would like to clarify that the vocalizations you hear from his kennel are not barking, but rather his intensive opera training in progress! Once he's out, this fancy-pants gentleman is incredibly chill and sweet, and he walks like a pro—no pulling, unless nature is making an urgent call. Mr. Bojangles is a certified foodie who appreciates a good gourmet treat but is just as happy with a classic peanut-butter bone. Basically, he’s a loyal companion who is effortlessly refined and ready to serenade his way into your heart!

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Meryl Streep

Mastiff Mixed Breed (Medium)

Female, 1 yr 10 mos

St. Louis, MO

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,

Story

🩷I learned much about adorable Meryl Streep yesterday as we buddied up and attended CARE’S Adoption Event at “Tower Grove Pride” event. This adorable one and a half year-old pup showed her happy self from the moment she jumped in the car and was the perfect backseat rider. 🩷As we walked to CARE’S tent Meryl walked well on the leash. The event was well attended and this sweet pup was friendly and sweet throughout. As participants of all ages came up to say “Hi” and gave her pets she was gentle to everyone. As other dogs passed she was mostly indifferent being content and enjoying the moment. When this precious girl was tired she laid down and fell fast asleep and stayed like that as the action continued all around her. After her short nap we headed back to the car. This precious, perfect girl made the day’s event fun, happy and totally enjoyable for me her sidekick💕 🩷All I could think is this fabulous pup belongs in a loving home and hopefully soon! Meryl Streep, is a treasure and would be a cherished pup for many families. -Her eye condition is called Cherry Eye and is not serious and will be taken care of by CARES clinic when she’s adopted. 🩷She is at CARE STL for you to meet and possibly fall in love just like me🩷🐾XOXO

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in De Soto, Missouri.

Mastiff puppies and dogs in De Soto, Missouri

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These Mastiffs are available for adoption close to De Soto, Missouri.

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Mastiff puppies and dogs in De Soto, Missouri

Learn More:

Adopt a Mastiff near you in De Soto, Missouri

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near De Soto, Missouri

These Mastiffs are available for adoption close to De Soto, Missouri.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in De Soto, Missouri

Mastiff shelters & rescues in De Soto, Missouri

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics