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Mastiff puppies and dogs in Valley Park, Missouri

Looking for a Mastiff puppy or dog in Valley Park, Missouri? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Valley Park, Missouri

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Valley Park, Missouri

These Mastiffs are available for adoption close to Valley Park, Missouri.
We'll also keep you updated on WALTER's adoption status with email updates.
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WALTER

Mastiff

Male, 5 yrs 1 mo
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Walter is friendly, outgoing, and his happiness is contagious. He walks well on a leash and seems to be potty trained. He knows sit, loves to play with squeekie toys, and wants all the pets.
We'll also keep you updated on BONES's adoption status with email updates.
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BONES

Mastiff

Male, 2 yrs 3 mos
Maryland Heights, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Hi, I’m Bones! My journey to the shelter? A classic mix-up. Picture this: I saw a squirrel, gave chase, and somehow ended up leading a conga line at a fancy garden party. Yup, crashed it! After a whirlwind of dance moves and giggles, I was kindly escorted here. I’m a smart, playful guy who can turn any dull moment into a party. Need a dash of joy and a partner in fun? I’m your pup! Let’s make every day a blast together! I am looking for a forever family or a family to love me until my forever family finds me. If you decide to fall head over heels in love and cannot part with me that is okay, too! Please call 314-951-1588 for more information!
We'll also keep you updated on Luke AG's adoption status with email updates.
Photo of Luke AG

Luke AG

Mastiff American Pit Bull Terrier

Male, 3 yrs 11 mos
St Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,
Story
Hi, I’m Luke, and I’m a big, lovable boy tipping the scales at just over 100 lbs! Don’t let my size fool you—I’m a happy, easygoing pup who just wants to play, explore, and cuddle. I’m all about the good things in life: squeaky toys, water play, long walks, and best of all—snuggle time on the couch. I’m a pro at giving hugs (though I’m working on not jumping up too hard to give them—oops!). I get along great with other dogs and kids, but because of my size and enthusiasm, I’d do best with older children who won’t get accidentally knocked over during playtime. I’m crate trained, housebroken, and walk nicely on a leash—unless there’s a squirrel… then it’s game on! I do have a slight prey drive, so a little guidance goes a long way. If you’re looking for a big-hearted, playful companion to fill your home with love (and maybe take up some space on your couch), I’m your guy. Let’s make forever happen! 🐾 Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)
We'll also keep you updated on Chili Mac's adoption status with email updates.
Photo of Chili Mac

Chili Mac

Mastiff

Male, Puppy
St Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Chili Mac!    This 11-month-old Cane Corso is a big, lovable goofball with a heart as giant as his paws! Chili Mac is equal parts cuddle bug and class clown — he’ll make you laugh one minute and melt into your lap the next.   He can be a little shy when meeting new people, but once he decides you’re cool, he’s all in! He’s great with dogs big and small (seriously — from 6 lbs to 120 lbs!), crate and potty trained, and already knows some basic commands.   Due to Chili Mac's size and clumsiness, he would do best in a home with older children. He would also be best with someone who has breed/guardian experience given some mouthy behaviors which are normal for the breed.   Chili Mac would love an active home with another dog friend or a human adventure buddy. Whether you’re hiking, road-tripping, or just lounging on the couch- as long as you don’t mind a little drool, he’s ready to be your ride-or-die!    If interested, please  complete the  Adoption Application  on our website at  www.NeedyPaws.org  and we will contact you.  Adopters must live within an hour’s drive of St. Louis, MO. Our $295 adoption fee includes up-to-date vaccinations, heartworm testing and preventative, spay/neuter and microchip. We are a 100% foster-based rescue and all of our dogs live in approved foster homes. We are dedicated to finding the best Forever Homes, and will perform home visits and conduct veterinarian and reference checks for each potential adopter. Visit this organization's web site to see any additional information available about this pet.December 26, 2025, 1:09 pm
We'll also keep you updated on Wendell's adoption status with email updates.
Photo of Wendell

Wendell

Mastiff Mixed Breed (Large)

Male, 6 yrs 3 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
Meet Wendell! 💛 Wendell is a 6-year-old Mastiff mix with a heart as big as his 75-pound frame! This gentle giant was taken in as a stray at just 7 months old and has spent the last several years living peacefully in a home with 15 other dogs of all ages and sizes. He’s truly a pack-friendly boy who gets along with everyone. Unfortunately, his owner had to downsize her dog family, so Wendell came to us. From the moment we met him, it was clear—this boy is pure love! 🥰 He’s chill, affectionate, housebroken, and oh-so-sweet. Wendell absolutely aced his temperament test and showed us just how easygoing and wonderful he is. If you’re looking for a loyal, laid-back companion who will fit right in with your family, Wendell is your guy! This handsome hunk of love is ready to give his heart to a forever home. 🐾 Housebroken 🐾 Dog-friendly with all shapes and sizes 🐾 Big, gentle, and so loving 🐾 Perfect family dog
We'll also keep you updated on Gus's adoption status with email updates.
Photo of Gus

Gus

Mastiff Mixed Breed (Large)

Male, Adult
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Gus! Gus is a charming 3-year-old mastiff mix with a heart as big as his paws. This gentle giant is friendly, outgoing, and absolutely loves people. He gets along wonderfully with other dogs and kids—just be prepared for a little “bull in a china shop” energy when he gets excited! Gus is house-trained, kennel-trained, and making great progress with his leash skills. He’s also an excellent car buddy, happy to settle in and enjoy the ride. If you’re looking for a lovable, goofy companion who brings joy wherever he goes, Gus might just be your perfect match! https://www.shelterluv.com/matchme/adopt/NAF/Dog

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Valley Park, Missouri.

Mastiff puppies and dogs in nearby cities

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Related breeds in Valley Park, Missouri

Mastiff shelters & rescues in Valley Park, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Valley Park, Missouri. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

8.9 miles

Animal Protective Association of Missouri

1705 South Hanley Road, St. Louis, MO 63144

Pet Types: cats, dogs, rabbits, small animals

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Rescue

10.2 miles

Gods Dogs Rescue of TX for St Louis Transport Stop

St Louis, MO 63146

Pet Types: dogs

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Shelter

10.2 miles

Humane Society of Missouri - Maryland Heights

11660 Administration Dr., (Page Ave. and Schuetz Road), Maryland Heights, MO 63146

Pet Types: cats, birds, dogs, rabbits, small animals

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Rescue

10.6 miles

Needy Paws Rescue

St Louis, MO 63125

Pet Types: dogs

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Rescue

14.1 miles

Charming Pet Rescue - MO Transport Stop

St. Louis, MO 63303

Pet Types: dogs

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Rescue

14.7 miles

Nala and Friends Dog Rescue - ST. LOUIS transport

St. Louis, MO 63118

Pet Types: dogs

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Shelter

16.1 miles

CARE STL

2700 Walnut Place, St. Louis, MO 63103

Pet Types: cats, birds, dogs, farm animals, rabbits, small animals

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Shelter

17.1 miles

Helping Strays of Monroe County

4221 Hanover Rd., Columbia, IL 62236

Pet Types: cats, dogs

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Rescue

19.2 miles

Is Today My Day Rescue

St. Louis, MO 63039

Pet Types: dogs

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Shelter

20.1 miles

Gateway Pet Guardians

725 N 15th St, East ST Louis, IL 62205

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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