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Mastiff puppies and dogs in O Fallon, Missouri

Looking for a Mastiff puppy or dog in O Fallon, Missouri? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in O Fallon, Missouri

These Mastiffs are available in O Fallon, Missouri.
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Photo of Margie Mae

Margie Mae

Mastiff Boxer

Female, Adult
Cottleville, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I am need of help rehoming Margie Mae. Long story, short version. I was awarded her in a divorce and have tried to keep her but I have no back yard. I mention this because we have to take her potty out front and she wants to defend our house and because of this she has gone after our neighbor’s dog. It’s weird because this is the only place that she acts like this. She adores all people and all dogs. She is fine at the dog park. Other places. Anywhere. Just not in front of our house. We’ve tried training and she is on medication for the anxiety. She is fixed and up to date with her shots. She is almost 6. She is ridiculously sweet 99% of the time. Her tail is always wagging. Just really want to find her a place where she can be calm and comfortable. She is a good girl. Happy to answer any questions. I am in Cottleville, MO Thank you in advance. $50 Rehoming fee. She just needs a good home.
Photo of JOCO

JOCO

Labrador Retriever Mastiff

Male, 2 yrs 9 mos
St. Peters, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
Meet Jocko. This 2-year-old, 98 lb Lab/Mastiff mix is feeling the stress of shelter life and is hoping someone will give him the chance to decompress in a home.Jocko is a sweet, affectionate boy who loves to: Lay in the sun Play fetch Snuggle with his peopleRight now, the shelter environment is overwhelming for him. The stress has shown through things like hyperventilating, excessive drooling, and a hotspot on his leg that needs time to heal. What Jocko really needs is a calm place where he can relax, recover, and just be a dog again.Outside of the kennel, Jocko is a friendly, energetic, playful companion. He is: Potty trained Crate trained Walks well on leash Knows “sit” Great with children (ages 2–8)Has lived successfully with catsThis active guy would love a family who can keep him busy with walks, playtime, and lots of love. More than anything, he needs someone willing to give him the patience, stability, and attention he deserves while he transitions out of the shelter.Please don’t let kennel stress be the only thing you see. Ask to meet Jocko outside of his kennel and see the sweet, loving dog he truly is.

Or, how about these Mastiffs in cities near O Fallon, Missouri

These Mastiffs are available for adoption close to O Fallon, Missouri.
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Photo of Margie Mae

Margie Mae

Mastiff Boxer

Female, Adult
Cottleville, MO
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I am need of help rehoming Margie Mae. Long story, short version. I was awarded her in a divorce and have tried to keep her but I have no back yard. I mention this because we have to take her potty out front and she wants to defend our house and because of this she has gone after our neighbor’s dog. It’s weird because this is the only place that she acts like this. She adores all people and all dogs. She is fine at the dog park. Other places. Anywhere. Just not in front of our house. We’ve tried training and she is on medication for the anxiety. She is fixed and up to date with her shots. She is almost 6. She is ridiculously sweet 99% of the time. Her tail is always wagging. Just really want to find her a place where she can be calm and comfortable. She is a good girl. Happy to answer any questions. I am in Cottleville, MO Thank you in advance. $50 Rehoming fee. She just needs a good home.
Photo of Luke AG

Luke AG

Mastiff American Pit Bull Terrier

Male, 4 yrs 4 mos
St Louis, MO
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,
Story
Hi, I’m Luke, and I’m a big, lovable boy tipping the scales at just over 100 lbs! Don’t let my size fool you—I’m a happy, easygoing pup who just wants to play, explore, and cuddle. I’m all about the good things in life: squeaky toys, water play, long walks, and best of all—snuggle time on the couch. I’m a pro at giving hugs (though I’m working on not jumping up too hard to give them—oops!). I get along great with other dogs and kids, but because of my size and enthusiasm, I’d do best with older children who won’t get accidentally knocked over during playtime. I’m crate trained, housebroken, and walk nicely on a leash—unless there’s a squirrel… then it’s game on! I do have a slight prey drive, so a little guidance goes a long way. If you’re looking for a big-hearted, playful companion to fill your home with love (and maybe take up some space on your couch), I’m your guy. Let’s make forever happen! 🐾 Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)
Photo of Finn AKA Gage JuM

Finn AKA Gage JuM

Mastiff Shepherd (Unknown Type)

Male, 7 yrs 4 mos
St Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
Finn may look like a rockstar with his striking Mastiff–Shepherd good looks, but at heart, he’s a big, soft lovebug. Weighing in at about 60 pounds, Finn has grown into a handsome boy with a beautiful gray and tan coat, soulful eyes, and an even bigger personality. Despite his star-quality appearance, Finn is more of a laid-back, easygoing guy—think Eeyore vibes, but with engines revved and ready to love. From the moment he wakes up, he’s prepared to shower his people with affection… and trust us, it’s A LOT of love! Finn does well with other dogs and does need a slow, proper introductions to new friends—both two-legged and four-legged. Once he knows you, he loves you deeply. He’s happiest when he has a buddy (human or canine) to share his world with. Affection is Finn’s specialty. When someone comes to greet him, he lights up, runs over with enthusiasm, and hands out slobbery kisses and big hugs like they’re backstage passes. His joy is genuine, his heart is huge, and he’s always thrilled to see his people. If you’re looking for a big, lovable, slightly goofy rockstar who will adore you endlessly, Finn is ready to take center stage in your heart. Local adoption only $200 (in TX)
Photo of HIPPIE

HIPPIE

Mastiff

Female, 1 yr 2 mos
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Hippie is a social, sweet girl who loves being wherever her people are. She enjoys plenty of pets, walks beautifully on the leash, and is always happy to stay close by for companionship. With her loving personality, Hippie is the perfect partner!
Photo of Freya

Freya

Mastiff

Female, 4 yrs 1 mo
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
Hi, I'm Freya! I'm a sweet mama and came with my 9 puppies. I'm a very good girl. I'm said to have had a few litters in the past and I'm ready to put motherhood behind me and have a little time for myself. Won't you spend it with me? If you're interested in adopting me, please fill out an application at www.polkcountyhumanesociety.org/adopt. You can also reserve an appointment to meet me. Some pets are in foster homes or may already have visits scheduled, so appointments help ensure I’ll be available. Polk County Humane Society is located in Bolivar, Missouri, and we welcome adopters from any state. We have access to a transport to Aurora, CO. Other out of state adopters either travel to Missouri or arrange & pay for air transport. Virtual meet and greets are available on the appointment request. ##2755149##
Photo of CHUM

CHUM

Mastiff

Female, 6 yrs
St. Louis, MO
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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Mastiff shelters & rescues in O Fallon, Missouri

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in O Fallon, Missouri. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

10.6 miles

Gods Dogs Rescue of TX for St Louis Transport Stop

St Louis, MO 63146

Pet Types: dogs

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Shelter

18.6 miles

Animal Protective Association of Missouri

1705 South Hanley Road, St. Louis, MO 63144

Pet Types: cats, dogs, rabbits, small animals

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Shelter

20.1 miles

Polk County Humane Society - St. Louis Transport

10900 Sunset Hills Plaza, St. Louis, MO 63127

Pet Types: cats, dogs

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Shelter

22.6 miles

Humane Society of Missouri

1201 Macklind Av, St. Louis, MO 63110

Pet Types: cats, birds, dogs, rabbits, small animals

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Shelter

24.3 miles

CARE STL

2700 Walnut Place, St. Louis, MO 63103

Pet Types: cats, birds, dogs, farm animals, rabbits, small animals

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Shelter

28.9 miles

Gateway Pet Guardians

725 N 15th St, East ST Louis, IL 62205

Pet Types: cats, dogs

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Shelter

32.3 miles

No Time to Spare Animal Rescue and Sanctuary

27933 Pendleton Lost Creek Rd, Warrenton, MO 63383

Pet Types: dogs, farm animals, horses

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Shelter

32.4 miles

Helping Strays of Monroe County

4221 Hanover Rd., Columbia, IL 62236

Pet Types: cats, dogs

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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