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Mastiff puppies and dogs in Oklahoma

Looking for a Mastiff puppy or dog in Oklahoma? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Oklahoma

Below are our newest added Mastiffs available for adoption in Oklahoma. To see more adoptable Mastiffs in Oklahoma, use the search tool below to enter specific criteria!
We'll also keep you updated on Maggie - Medical Hold's adoption status with email updates.
Photo of Maggie - Medical Hold

Maggie - Medical Hold

Mastiff

Female
EDMOND, OK
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Good with cats, House-trained,
Story
You can fill out an adoption application online on our official website.    PLEASE NOTE: GPMR communicates primarily by email.  If you have any questions regarding one of our Mastiffs, please read their bio and if you still have questions - drop us an email at GPMastiffRescue@gmail.com.  If you have questions about our adoption procedures, please go to our page called 'Adoption Info.'  We answer email inquiries daily.    GPMR does not have a shelter. All of our dogs are kept in loving foster homes. We must have a completed adoption application on file before meeting any of our mastiffs.    GPMR adopts to the states of Oklahoma, Texas, Kansas, Arkansas, Missouri, Louisiana and parts of Colorado.  !!!Any mastiffs being adopted out of the state of Oklahoma require a health certificate to be paid for by the adopter!!!       Meet Maggie! Maggie is an estimated 7-year-old Mastiff who landed in an Arkansas shelter after her owner went to jail. She’s already been through so much — right after we picked her up from the shelter and took her to the vet, we discovered she had a life threatening uterine infection called a pyometra. Thankfully we got her just in time, she was hospitalized at our vet and spayed to take care of the infection. She's extremely underweight and so we're working on getting her healthy. She's also postitive for heartworms. It's clear she was neglected for some time.  Maggie has been dog tested and she’s been very sweet. She does well with the other Mastiff in her foster home and the cats as well. Her foster reports she's a pretty easy keeper. She's got a road ahead of her to get healthy, but we're commited to getting here there! She'll be available for adoption once she finishes all of her veterinary care. Maggie is being fostered in Amarillo, TX Visit this organization's web site to see any additional information available about this pet.Save a Mastiff...Adopt, Foster, Volunteer!December 17, 2025, 9:27 pm
We'll also keep you updated on Apollo's adoption status with email updates.
Photo of Apollo

Apollo

Mastiff/Terrier (Unknown Type, Medium)

Male, 4 yrs
Vinita, OK
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with cats,
Story
Hello. My name is Apollo. Here is a little bit about me. I like most other dogs. Kids are my bestie's. I know basic manners, and I am potty trained. I get the zoomies after my morning coffee. My only issue is .... I'm ugly 😭 Or at least my skin is. I got to see the dog doctor and he gave me some medicine. They say that I might have to take it for the rest of my life. I think I could deal with that, as long as I'm not itchy anymore. I really hope it works fast. I'm tired of scratching and hurting. I want to be handsome again.... 🥺 So....If you can see past my flaws, please come and adopt me! I would like to go home with you! PAAS-Vinita 918-256-7227 628 S. Wilson St. Vinita, OK 74301
We'll also keep you updated on Daisy's adoption status with email updates.
Photo of Daisy

Daisy

Mastiff

Female
EDMOND, OK
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained,
Story
You can fill out an adoption application online on our official website.    PLEASE NOTE: GPMR communicates primarily by email.  If you have any questions regarding one of our Mastiffs, please read their bio and if you still have questions - drop us an email at GPMastiffRescue@gmail.com.  If you have questions about our adoption procedures, please go to our page called 'Adoption Info.'  We answer email inquiries daily.    GPMR does not have a shelter. All of our dogs are kept in loving foster homes. We must have a completed adoption application on file before meeting any of our mastiffs.    GPMR adopts to the states of Oklahoma, Texas, Kansas, Arkansas, Missouri, Louisiana and parts of Colorado.  !!!Any mastiffs being adopted out of the state of Oklahoma require a health certificate to be paid for by the adopter!!!       Meet Daisy! This sweet girl was found wandering in a small town in Oklahoma. She had been spotted in an area for a few weeks so we suspect she was dumped. When no owner was able to be located, a local family got her safely secured in their yard and reached out to find her rescue. Daisy is estimated at 1.5 years old and she's about 115 lbs. She is house trainied, good with free roaming in the home and has already figured out the doggie door! Her foster parents are working on basic manners and she needs basic leash training. She is a friendly girl and your typical velcro Mastiff. Other than a mild ear infection, she appears to be in good health. We treated her for the ear issue and for intestinal parasites and she was thankfully negative for heartworms! Daisy has been good with dogs of all sizes. She loves her toys! She's still very puppy and a little too much for small kids. She would be OK in a home with older kids or an adult only home would be fine too. At this time we don't know if she is good with cats. Daisy is being fostered in Tulsa, OKVisit this organization's web site to see any additional information available about this pet.Save a Mastiff...Adopt, Foster, Volunteer!December 15, 2025, 10:21 pm
We'll also keep you updated on Opal's adoption status with email updates.
Photo of Opal

Opal

Mastiff/Black Mouth Cur

Female, 5 yrs
Duncan, OK
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with dogs, Not good with cats, House-trained,
Story
After being with us almost a year we thought Opal had finally found her forever home but by no fault of her own she was returned only three days after being adopted. This sweet, calm, well mannered, and gentle girl has so much love to give and simply dreams of a family who will cherish her as much as she will cherish them. She longs for a home where she can be the only pet, soft beds, warm cuddles, and days filled with attention, companionship, and joy. Opal has been patient, but her heart aches for the chance to finally have a home where she’s not just another rescue dog, but a beloved member of the family she’s been waiting for all this time. Opal is a 5 year old Mastiff/black mouth cur mix who loves everyone she meets especially kids! She is fully house and kennel trained, knows basic commands, walks great on a leash, and loves car rides! Opal is spayed, up to date on vaccines, current on flea/tick/heartworm prevention, and heartworm tested negative. Opal’s adoption fee has been sponsored so she is FREE to a loving home!
We'll also keep you updated on Goku's adoption status with email updates.
Special Needs
Photo of Goku

Goku

Mastiff

Male, Senior
Carnegie, OK
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Needs special attention,
Story
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We'll also keep you updated on Bobbi - Adoption pending's adoption status with email updates.
Photo of Bobbi - Adoption pending

Bobbi - Adoption pending

Mastiff

Female
EDMOND, OK
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained,
Story
You can fill out an adoption application online on our official website.    PLEASE NOTE: GPMR communicates primarily by email.  If you have any questions regarding one of our Mastiffs, please read their bio and if you still have questions - drop us an email at GPMastiffRescue@gmail.com.  If you have questions about our adoption procedures, please go to our page called 'Adoption Info.'  We answer email inquiries daily.    GPMR does not have a shelter. All of our dogs are kept in loving foster homes. We must have a completed adoption application on file before meeting any of our mastiffs.    GPMR adopts to the states of Oklahoma, Texas, Kansas, Arkansas, Missouri, Louisiana and parts of Colorado.  !!!Any mastiffs being adopted out of the state of Oklahoma require a health certificate to be paid for by the adopter!!!       ***This Mastiff is part of our 'Fall in Love' adoption event and her adoption fee is waived!Meet Bobbi – A Gentle Soul Looking for Her Forever Home Bobbi is a 3-year-old fawn English Mastiff, she is a 'Fluffy' where she has a longer coat. This is due to a recessive gene and it's not very common to see. She is gorgeous! She has a heart as big as her paws. This sweet girl is the definition of a gentle giant—soft, sensitive, and full of love, just waiting to be shared. Recently surrendered by her previous owners, Bobbi is adjusting to a new chapter in life. She’s a quiet, affectionate companion who prefers the comfort of a calm environment and the gentle presence of a kind human by her side.   Bobbi is especially drawn to women and feels most at ease in a home where she can build trust at her own pace. She’s timid at first—new people, places, and sounds can be overwhelming—but once she feels safe, her sweet personality begins to shine. She’ll nuzzle into your hand for pets, follow you from room to room, and rest her head on your lap. Because of her shy nature, Bobbi would thrive in a peaceful home with a patient adopter who understands that confidence takes time. She’s not the kind of dog who will leap into new experiences, but with gentle encouragement and positive reinforcement, she’s already making strides.  Bobbi is house-trained, well-behaved indoors, and gets along well with other calm, respectful dogs. She’s not overly playful but enjoys the quiet company of other dogs who give her space and help her feel secure. She is being fostered in a home with a cat and has been curious and friendly towards it. Due to her size and sensitivity, Bobbi would do best in a home without young children. Older, dog-savvy kids who understand how to respect her boundaries could be a good fit. A fenced yard and a predictable routine would help her continue to grow and feel secure. Bobbi is ready to find a forever home where she can feel safe, loved, and truly part of the family. Bobbi is being fostered in Ft. Smith, ARVisit this organization's web site to see any additional information available about this pet.Save a Mastiff...Adopt, Foster, Volunteer!December 17, 2025, 9:27 pm

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Oklahoma.

Mastiff puppies and dogs in Oklahoma cities

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Mastiff shelters & rescues in Oklahoma

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Oklahoma. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Forever Yours Dog Rescue

PO Box 890547, Oklahoma City , OK 73189

Pet Types: dogs

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Rescue

405 Animal Rescue

Oklahoma City , OK 73118

Pet Types: cats, dogs

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Rescue

Friends with Four Paws, OKC

Oklahoma City , OK 73112

Pet Types: cats, dogs

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Rescue

Great Plains Mastiff Rescue Foundation

PO BOX 6173, EDMOND , OK 73083

Pet Types: dogs

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Rescue

Pawsitive Pals Foundation

Duncan , OK 73533

Pet Types: cats, dogs

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Rescue

Rainbow Bridge Can Wait

526 E Oklahoma st, Carnegie , OK 73015

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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