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Mastiff puppies and dogs in Oregon

Looking for a Mastiff puppy or dog in Oregon? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Oregon

Below are our newest added Mastiffs available for adoption in Oregon. To see more adoptable Mastiffs in Oregon, use the search tool below to enter specific criteria!
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Lola

Mastiff/Labrador Retriever

Female, Puppy
Gearhart, OR
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
We adopted Lola in October 2025 when she was 10 weeks old from a friend whom just had a litter of pups. We have been happy with her so far however our living situation changed in February when my elderly mom moved in with us and needs full time care. Lola needs lots of attention and play time which we are unable to offer with all the needs of my mom. We just want her in a loving home with someone who will give her the time and attention she needs. She’s very loyal and loves to cuddle. Our older pug and main coon cat get along with her great. She’s friendly and quite strong, so she needs a family that can handle her strength.
Photo of Chuckles

Chuckles

Mastiff/Mixed Breed (Medium)

Male, 4 yrs 3 mos
Salem, OR
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats,
Story
Howdy there, I’m Chuckles. I’m a 4 year old, 80 lb. Mastiff mix with a big heart, a bigger frame, and a personality that just needs a minute to shine. I can be a little nervous when I first meet new people or find myself in new situations. I like to take things in slowly at first, make sure everything feels safe, and confirm you are not secretly a broom or a suspicious moving object. Once I realize you are kind and safe, I come out of my shell pretty quickly, especially if you have treats. Snacks are basically my love language. A few good treats and suddenly I am your best friend, emotional support giant, and personal shadow all rolled into one. I am a very sweet boy who loves affection from my people. I enjoy leaning in for pets, hanging out close by, and being part of whatever is going on. I may be large, but I have a very soft heart and I am happiest when I am near my humans. I also enjoy going on walks and adventures, taking in the world at a steady, thoughtful pace while I sniff everything that might possibly be important. I do well with other dogs and enjoy their company. As for cats, I have lived with a cat before and did well. I would do best with kids over the age of 6 who understand that I may need a little space when I am first adjusting or feeling unsure. Once I settle in, I am affectionate, goofy, and deeply loyal, but I appreciate people who let me warm up at my own pace. So if all of this sounds amazing to you, please come and meet me! My adoption fee is $295 and I'm neutered, vaccinated and microchipped. Apply to meet me today!
Photo of Polo

Polo

Mastiff

Male, Adult
Salem, OR
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
What my friends at OHS say about me:I really enjoy the company of my human friends.Just like a bear, I am snuggly, cute, and love butt scratches.I'm a social guy! I've lived with small dogs and kids and love being a part of the action.I love to be the center of attention. All eyes and pets on me, please!Shy and Nervous: I can be worried about new people, new surroundings and touch. I prefer to take things at my own pace and will need to live in a calm environment.The type of home I'm looking for:It could be with you! Click here to learn about the adoption process.You can also stock up on food and treats using our online store by clicking here. Primary Color: Sable Secondary Color: Ticked Weight: 77 Age: 2yrs 1mths 2wks
Photo of Dozer

Dozer

Mastiff

Male, Adult
Tigard, OR
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
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Story
Dozer is a neutered male, black/white Mastiff Hi! I'm Dozer! I am deaf! I really don't know how to play. It’s kind of sad. I have a little routine here - I just go in my pen, eat a few bites, drink then run back out for a treat. I like being near my people & will follow you around. I am not interested in playing ball. I really just don't know what to do with myself other than just enjoy life. I am so sweet, according to my foster. So if you don't mind a good-sized velcro dog, I'm your guy! ##2498995##
Photo of Lee

Lee

Mastiff

Male, 7 yrs
Waldport, OR
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with dogs,
Story
At 108lbs this big boy is basically a weighted blanket with legs. Lee is a gentle giant, professional tail wagger, expert couch hog, and full-time happy boy! Despite being approximately, the size of a baby rhinoceros, he is incredibly sweet, gentle, and convinced he belongs in your lap. He would prefer to be your one and only canine king as other dogs aren't really his thing. Honestly, he'd much rather spend his time focusing on his true passion. Snacks! Cheese? Amazing. Treats? Incredible. The sound of a bag opening from three rooms away? Life changing! His hobbies include smiling at everyone he meets, taking up most of the bed, and supervising all kitchen activities in case food accidentally falls on the floor. If you've ever wanted a best friend who looks intimidating but is just a giant marshmallow powered entirely by love and snacks, this big lovable goof is your guy!
Photo of beanie

beanie

Mastiff/German Shepherd Dog

Female, Young
Hillsboro, OR
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with cats, Needs experienced adopter, House-trained,
Story
Beanie simply needs more attention with my long work hours, and my family gone she deserves a better chance. she loves to snuggle, and play tug

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Oregon.

Mastiff puppies and dogs in Oregon cities

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Mastiff shelters & rescues in Oregon

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Oregon. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Shelter

Rogue Valley Humane Society

429 NW Scenic Dr, Grants Pass , OR 97526

Pet Types: cats, dogs

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Rescue

Campbell Safe Haven Rescue and Rehabilitation

Suite 109, North Bend , OR 97459

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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