Adopt

Great Dane puppies and dogs in Maryland

Looking for a Great Dane puppy or dog in Maryland? Adopt a Pet can help you find an adorable Great Dane near you.

Picture of Great Dane

Adopt a Great Dane near you in Maryland

Below are our newest added Great Danes available for adoption in Maryland. To see more adoptable Great Danes in Maryland, use the search tool below to enter specific criteria!
We'll also keep you updated on Nova's adoption status with email updates.
new badge
Photo of Nova

Nova

Great Dane

Female, 5 mos
Frederick, MD
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, House-trained,
Story
Nova-Great Dane X female puppy, ~ 5 mo. (Jan. 2026) Contact rescuebc@hotmail.com for an application. Nova and her sister came to a Dog Trainer as owner surrenders when their prior owner could no longer care for them. The Dog Trainer coordinates a Prison Program and Nova has been in the Program for a while now. She's doing great. Nova is now house trained and crate trained. She is obedience trained and ready for her new family. Nova will probably be a large girl, maybe 60# as an adult. She will enjoy an active lifestyle. She has not lived with cats or children, but done excellent in the Training program. She gets along well with other dogs. Nova's adoption fee is $400 to help cover the medical costs of getting ready for adoption. For our application, please email rescuebc@hotmail.com Please include your location and a phone number for future communication.
We'll also keep you updated on Starr's adoption status with email updates.
new badge
Photo of Starr

Starr

Great Dane

Female, 5 mos
Frederick, MD
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, House-trained,
Story
Starr-Great Dane X female puppy, ~ 5 mo. (Jan. 2026) Contact rescuebc@hotmail.com for an application. Starr and her sister came to a Dog Trainer as owner surrenders when their prior owner could no longer care for them. The Dog Trainer coordinates a Prison Program and Starr has been in the Program for a while now. She's doing great. Starr is now house trained and crate trained. She is obedience trained and ready for her new family. Starr will probably be a large girl, maybe 60# as an adult. She will enjoy an active lifestyle. She has not lived with cats or children, but done excellent in the Training program. She gets along well with other dogs. Starr's adoption fee is $400 to help cover the medical costs of getting ready for adoption. For our application, please email rescuebc@hotmail.com Please include your location and a phone number for future communication.
We'll also keep you updated on Gabby's adoption status with email updates.
Photo of Gabby

Gabby

Great Dane/Catahoula Leopard Dog

Female, 2 yrs 6 mos
Silver Spring, MD
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
-
Story
If you are interested in adopting this dog, please fill out an Adoption Questionnaire athttps://petstablished.com/adoption_form/43315/generic.You can learn about the adoption process by visiting: http://www.k-9lifesavers.org/howtoadopt/.Dog's Name:   Gabby  (GAB0126SOPFDHW)Estimated Breed:   Great Dane / Catahoula / Pointer mixApproximate Age:   2-3 yearsApproximate Weight:   50 lbsCurrently Living at:   BoardingAdoption Fee:   $450DOG'S DESCRIPTION:   Meet Gabby—a gorgeous Great Dane mix with long legs, a warm heart, and so much love to give.     Gabby is a young lady who turns heads everywhere she goes, but it’s her sweet, easygoing personality that really makes people fall in love. She’s gentle, affectionate, and the kind of dog who seems to understand that life is better when it’s shared with people who care. Whether she’s lounging gracefully or leaning in for affection (classic Dane move!), Gabby is happy just being near her humans.     While Gabby is currently heartworm positive, the good news is that K-9 Lifesavers is covering her treatment, and with a little rest, TLC, and patience, she’ll be feeling like her best self in no time. If you’re ready for a big, beautiful best friend with an even bigger heart, Gabby is ready to join your pack.  Apply today! To learn more about heartworm please visit: https://www.webmd.com/pets/dogs/features/heartworms-in-dogs-facts-and-mythsYour new pet will require a refresher in house-training. K-9 Lifesavers strongly recommends all new adopters enroll their new pet into obedience training. This provides for an easier transition into a new home, ensures the dog remains well socialized, and helps form a bond between the dog and the new family.    Adoption fees cover basic vetting, rabies (if puppy is old enough), distemper/parvo vaccinations, deworming, monthly heartworm prevention while in our care (if old enough), monthly flea/tick prevention while in our care, and transport costs. K-9 Lifesavers will also cover the cost of spay/neuter at our partner vet at 6 months of age or reimburse adopter for up to the amount of our partner vet cost should you choose to spay/neuter at your own vet.Foster Program:    Foster homes provide for the temporary care of a rescue until the dog is placed into a loving, forever home.  For more information on becoming a foster parent, and our Foster Program, visit http://www.k-9lifesavers.org/foster/ or email our Foster Coordinator at foster@k-9lifesavers.orgSPONSOR ME! Help Save Lives!    Make a tax-deductible donation today and help save a life. Donations help us offset boarding costs and additional medical treatment for those dogs who need it.  K-9 Lifesavers receives NO federal funding and survive with your generous support! We are all volunteer based organization so every cent from your donation goes directly to the dogs in our care. Visit: http://www.k-9lifesavers.org/donate/For more information on K-9 Lifesavers, or to view a complete listing of all our Adoptable Dogs, visit our website at www.k-9lifesavers.org.Please "like" our Facebook page for the most current events and new dogs!Thank you for considering a rescue dog! ##2631296##
We'll also keep you updated on Winston's adoption status with email updates.
Photo of Winston

Winston

Great Dane

Male, 1 yr 3 mos
Bethesda, MD
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained,
Story
Winston was rescued as a puppy living life in a crate. He was brought home to relatives who are both wheelchair-bound. This puppy grew into a Great Dane, lol! Winston is currently more than his adult owners can physically keep up with. He is trained to an electronic collar so he can run around his country yard and play with the other dog from the house. He is good with kids and loves to sit on the couch like a human, with his front paws resting on the ground. He is a big happy gentle giant looking for a home that can help him expend his energy better. He is loves his toys and would especially love a person to play with him and a lap that he can sit on, lol! If you’re looking for a big gentle giant, please contact irondawgs13@gmail.com for adoption application.
We'll also keep you updated on Skye's adoption status with email updates.
Photo of Skye

Skye

Great Dane/Mixed Breed (Large)

Female, 3 yrs
Frederick, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs,
Story
Current Location: Rockville, MD Hello! My name is Skye! I'm coming to OPH on 1/9/2026. Please check back soon for updates on my personality, and to see adorable new photos. I’m looking for my forever family! Is that with you? If so please click “apply for adoption” or submit an application through the Adopt tab. Let’s get our family started!
We'll also keep you updated on Lyric's adoption status with email updates.
Photo of Lyric

Lyric

Great Dane/Mixed Breed (Medium)

Female, 8 mos
Hagerstown, MD
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs,
Story
Lyric is a stunning merle Great Dane with puppy energy turned all the way up and joy to match. This girl is playful, goofy, and always ready for her next adventure. She would thrive in an active home or with another dog who can keep up with her play style and enthusiasm for life. Lyric does great with kids and other dogs, but because she is big, bouncy, and still learning her size, she would do best in a home with older children. She walks well on a leash and is eager to please, making her a great candidate for continued training and fun outings. Lyric is the kind of dog who will make you laugh daily, keep you moving, and love you with her whole oversized heart. Adoption fee is $300 and covers spay, vaccines, parasite prevention, and microchip. Apply at www.fullcirclerescueandsanctuary.com

Search for a Great Dane puppy or dog

Use the search tool below to browse adoptable Great Dane puppies and adults Great Dane in Maryland.

Great Dane puppies and dogs in Maryland cities

Great Dane shelters & rescues in Maryland

There are animal shelters and rescues that focus specifically on finding great homes for Great Dane puppies in Maryland. Browse these Great Dane rescues and shelters below.

Here are a few organizations

Rescue

Reach Out Rescue & Resources

P. O. Box 542, Westminster , MD 21158

Pet Types: cats, dogs

More an arrow icon

Rescue

K-9 Lifesavers

Silver Spring , MD 20904

Pet Types: dogs

More an arrow icon

Rescue

For Pete's Sake Rescue - DC, VA, MD

Bethesda , MD 20816

Pet Types: cats, dogs

More an arrow icon

Rescue

Bourbon County Rescue

1275 W Patrick Street, Frederick , MD 21702

Pet Types: cats, dogs, rabbits, small animals

More an arrow icon

Rescue

Operation Paws for Homes - MD Chapter

Frederick , MD 21703

Pet Types: dogs

More an arrow icon

Rescue

Serendipity Animal Rescue Inc

La Plata , MD 20646

Pet Types: cats, dogs

More an arrow icon

Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

magnifying glass with cat and dog

Want to learn more about adopting a Great Dane puppy or dog ?

We've got all the info you need on adopting and caring for a Great Dane puppy . Check out the links below for everything you ever wanted to know about Great Dane puppies and adults .

Great Dane information

clipboard with list

Where do Great Danes come from? How many types of Great Danes are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Great Dane.

Learn More an arrow icon