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Mastiff puppies and dogs in Guadalupe, Arizona

Looking for a Mastiff puppy or dog in Guadalupe, Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Guadalupe, Arizona Other pups in Guadalupe, Arizona Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Guadalupe, Arizona Mastiff shelters and rescues in Guadalupe, Arizona Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Guadalupe, Arizona

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Guadalupe, Arizona

These Mastiffs are available for adoption close to Guadalupe, Arizona.
We'll also keep you updated on Moose's adoption status with email updates.
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Moose

Mastiff Great Dane

Male, Young
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I rescued this sweet boy May 1st 2025 from a neglected home. At this time I had a large house with a backyard, unfortunately now I have moved out and have been traveling the country with him since early October and he has not handled life on the road very well. He needs proper kennel training and also a yard to run around in. He’s not the type for hotel rooms or small Airbnbs. He’s the best dog at dog parks, plays kindly with kids, and has never show any aggression to other animals. He is an extreme cuddle buddy and gentle giant, but it’s the time away where he struggles. He has broken out of every kennel I’ve purchased and can open nearly every door except round doorknobs. Ideal situation for him is something with a yard and even another dog to play with. I am planning on moving to Idaho once I get my condo listed for sale (will be listed on January 7th). It’s not fair for him to relocate to a smaller place where I am gone working for up to 8 hours at a time with no supervision.

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We'll also keep you updated on Hazel's adoption status with email updates.
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Hazel

Mastiff Weimaraner

Female, 1 yr 6 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Hazel — a big girl with an even bigger heart! Hazel recently joined our rescue from Holbrook Animal Care and Control. Since being in our care, she’s quickly won over volunteer’s hearts with her sweet and goofy personality. Hazel is fine tuning her leash manners but enjoys her daily walks with volunteers. She knows basic commands and would love to continue to learn. Hazel is super playful and loves toys. This girl is super sweet and loves affection. Hazel just wants a person to love and a home to relax in. Can you be the one to give it to her?

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We'll also keep you updated on Barkley's adoption status with email updates.
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Barkley

Mastiff Shar Pei

Male, Adult
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered,
Story
Barkley is a great dog. He's a protector, sweet and loyal. He's beautiful. We rescued him 4 years ago, after our previous dog passed away after 13 years. We love him and will keep until a good home is found but he's not a good fit for our family. He needs social attention. He has anxiety and separation issues. He will follow u every where. No aggression. Never bitten anyone. He is great around our kids but when they start playing or get excited he gets to excited with them. Jumping and bumping into them. He's kncoked them down and into objects. This is our main reason for wanting to rehome him. Not good with small children for that reason. He's good with small dogs, as we have another small dog but he is not good with other large dogs. We want to make sure he goes to a very good and loving home where he fits well.

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We'll also keep you updated on Hope's adoption status with email updates.
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Hope

Mastiff Cane Corso

Female, 3 yrs 8 mos
Gilbert, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Hope! Hope’s name says it all—she’s the definition of resilience and new beginnings. Likely a Mastiff/Cane Corso mix, she currently weighs about 60 pounds (and still filling out beautifully). When rescued, Hope was heartbreakingly underweight at just 56 pounds, likely abandoned by a breeder and left to survive on her own. But through it all, her gentle, loving spirit never wavered. Now healthy, happy, and about 3–4 years old, Hope is blossoming into the incredible dog she was always meant to be. She’s a perfect mix of cuddle companion and adventure buddy—content to curl up next to you for a movie night or join you on a walk or hike. She’s playful, affectionate, and has that soulful look that melts your heart. Hope walks beautifully on a leash, adores people, and just wants to be close to her humans. She’s ready for a home where she can continue to thrive, surrounded by love, comfort, and a family who sees how special she truly is. * Fully vetted * Sweet, affectionate, and fun-loving * Loves walks, hikes, and being by your side * Ready to give (and receive!) all the love If you think Hope might be your perfect match, please email adopt@valleydogs.org for more information.

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We'll also keep you updated on BLUE JAY's adoption status with email updates.
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BLUE JAY

Mastiff

Male, 8 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
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We'll also keep you updated on Hulk's adoption status with email updates.
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Hulk

Mastiff Cane Corso

Male, 3 yrs 9 mos
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
💚 Gentle Giant Hulk 💚 Meet Hulk, a 2-year-old Mastiff. Despite his big name and size, Hulk is more of a shy, sensitive soul than a superhero. But with time, patience, and calm handling, Hulk shows he can tolerate gentle pets and slowly build trust. What makes Hulk special 💪 Big, handsome Mastiff boy 💚 Sensitive and gentle-natured despite his size 🐾 Looking for a safe space to relax and rebuild confidence What Hulk needs 🕰️ Extra patience and time to decompress 🏡 A calm, structured environment without pressure 🤝 A kind person who can help him come out of his shell

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Guadalupe, Arizona.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Guadalupe, Arizona

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Mastiff shelters & rescues in Guadalupe, Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Guadalupe, Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

8.3 miles

Alone No More Dog Rescue

Phoenix, AZ 85008

Pet Types: dogs

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Rescue

9.8 miles

Valley Dogs

P.O. Box 364, Gilbert, AZ 85299

Pet Types: dogs

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Shelter

13 miles

Maricopa County Animal Care & Control West Animal Shelter

2500 S. 27th Avenue, Phoenix, AZ 85009

Pet Types: dogs

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Rescue

15.5 miles

FREEDOM BROTHERS RESCUE

Phoenix, AZ 85028

Pet Types: dogs

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Rescue

17.5 miles

Love Them All Sanctuary + Rescue

Scottsdale, AZ 85259

Pet Types: dogs

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Shelter

18.1 miles

HALO Animal Rescue

3227 E. Bell Rd., Ste D151, Phoenix, AZ 85032

Pet Types: cats, dogs

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Rescue

24.3 miles

Regal Dane Rescue

4410 W UNION HILLS DR STE 7-187, GLENDALE, AZ 85308

Pet Types: dogs

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Rescue

26.8 miles

AZ Mastiff Rescue- English Mastiff and Other Mastiff and Giant breeds

Goodyear, AZ 85338

Pet Types: dogs

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Rescue

32 miles

Handover Rover

Scottsdale, AZ 85262

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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