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Mastiff puppies and dogs in Phoenix, Arizona

Looking for a Mastiff puppy or dog in Phoenix, Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Phoenix, Arizona Other pups in Phoenix, Arizona Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Phoenix, Arizona Mastiff shelters and rescues in Phoenix, Arizona Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Phoenix, Arizona

These Mastiffs are available in Phoenix, Arizona.
Photo of BLUEBERRY

BLUEBERRY

Mastiff

Male, 3 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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STILETTO

Mastiff Boxer

Female, 5 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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Tide

Labrador Retriever Mastiff

Male, 1 yr 6 mos
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
Hi, I`m Tide!- Sweet boy who loves his treats and lots of attention!- Being treat motivated sure does help with training!- I love to play with lots of toys and would be happy to show you all of my tricks!- I`m not recommended to be a sibling for cats.- I have mixed feelings when meeting other dog friends, so if you have any siblings for me at home let me meet them first before adopting to ensure a great match!- I can be bit jumpy when excited so I am recommended to be with kids aged elementary and older.- I need to get my energy out so a good few walks a day with plenty of playtime sounds great!No appointment necessary!AAWL requires that all adopted dogs leave with a leash and collar and all cats leave in a carrier.

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Mushu

Boxer Mastiff

Male, Young
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
House-trained, Spayed or Neutered,
Story
Meet Mushu! Mushu is a Boxer/Mastiff mix born on April 9, 2025. He's a sweet, affectionate boy who loves people and thrives on attention and affection. Mushu is an indoor dog, fully housebroken, and already trained, making him a wonderful companion for the right home. While Mushu is dog-selective, he is an amazing friend to his humans and enjoys being part of the family. He's loyal, loving, and happiest when he's spending time with the people he cares about. If you're looking for a devoted companion who will reward you with endless love and friendship, Mushu could be the perfect match. Adoption fee $40 please call or text to meet Mushu (602)908-6215 October 10, 2026, 7:48 pm

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Or, how about these Mastiffs in cities near Phoenix, Arizona

These Mastiffs are available for adoption close to Phoenix, Arizona.
Photo of BLUEBERRY

BLUEBERRY

Mastiff

Male, 3 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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Photo of STILETTO

STILETTO

Mastiff Boxer

Female, 5 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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Photo of Janice

Janice

English Mastiff

Female, Young
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Janice is a female Mastiff mix pup who recently joined the Big Hearts for Big Breeds crew. She's got the kind of sweet face that instantly melts hearts! Janice is another sibling from the beloved “Friends” foster pups, and she’s already showing what a special girl she is. Playful and curious, Janice is settling right into her new foster home and learning the ropes alongside other large dogs. She enjoys playtime, companionship, and is gaining confidence every day as she adapts to her new surroundings. With her loving nature and easygoing personality, Janice is ready to grow into a wonderful companion for a family who will continue guiding her, loving her, and cheering her on as she blossoms.

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Photo of Maple

Maple

English Mastiff

Female, Young
Mesa, AZ
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Maple is a one-year-old Mastiff mix who may be petite in size, but she’s overflowing with personality, playfulness, and charm. Now in the care of Big Hearts for Big Breeds, this sweet young girl is ready to find a forever family to grow up with. Maple is the sibling of some familiar Big Hearts faces—the beloved “Friends” crew, Rachel, Monica, Phoebe, and Janice—but she’s just beginning her own rescue journey. Like her siblings, she is shy and timid at first, but she truly has a loving heart and is eager to make lasting connections with the people around her. Still very much a puppy, Maple loves to play and brings a fun, energetic spirit wherever she goes. She does well with other dogs and was around cats when she was younger, giving her a solid foundation as she continues to learn and mature. With continued guidance, socialization, and plenty of positive experiences, she’s sure to blossom into an incredible companion. Maple is looking for a family that will embrace her youthful enthusiasm, celebrate her milestones, and give her all the love she deserves. If you’re searching for a playful, affectionate best friend with a bright future ahead, Maple might just be the perfect addition to your home.

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Special Needs
Photo of Dahlia

Dahlia

English Mastiff Great Dane

Female, Senior
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Needs special attention, House-trained, Spayed or Neutered,
Story
Dahlia is a eight-year-old Mastiff mix with the softest heart and the gentlest soul. When her time was running out at the county shelter, Big Hearts for Big Breeds stepped in to give her the second chance she so deeply deserves. Despite everything she’s been through, Dahlia remains incredibly sweet and trusting. She leans into love, soaking up gentle pets and quiet companionship. She is a calm, tender presence — the kind of dog who simply wants to rest her head beside you and feel safe. Dahlia is considered special needs. She is almost blind and will be undergoing eye removal surgery to keep her comfortable and pain-free. Even with limited vision, she navigates the world with quiet bravery, relying on kindness, routine, and the reassurance of her people. Her resilience is nothing short of inspiring. This beautiful girl doesn’t need much — a soft place to land, a patient home willing to help her adjust, and hearts big enough to see past her medical needs and into her incredible spirit. If you believe that every dog deserves safety, dignity, and love — especially the ones who need a little extra — Dahlia is waiting for you.

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Photo of SWIRL

SWIRL

Mastiff

Male, 4 yrs 3 mos
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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These pups are in Phoenix, Arizona too!

Below are our newest added Mastiffs available for adoption in Phoenix, Arizona. To see more adoptable Mastiffs in Phoenix, Arizona, use the search tool below to enter specific criteria!
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Atlas 2

St. Bernard

Male, 1 yr 3 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Thank you for your interest in adopting! To learn more about the pets we have available for adoption or to complete our online application, go to: https://azhartt.org/programs-services/adopt/Once your application is submitted, you will receive an email that explains our adoption process.Please note that we do not adopt on a first-come, first-served basis. Our adoption team works very hard to match the pets in our care with a family that best suits the pet`s needs.

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Photo of Charlie

Charlie

St. Bernard

Male, 1 yr 1 mo
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Hello! I`m a cheerful young dog who loves walks and dog toys. My favorite dog toys are those I can gnaw on all day long and those I can tear the stuffing out of. A good rubber bone is one of life`s finest things! Also, I`ve done well with other dogs in the past. As a big puppy who doesn`t know his size, sometimes I get a little too jumpy in my enthusiasm. With a sufficient outlet for my energy and some training on my people skills, I`m sure I could be the dog of your dreams! If you think I might be the dog for you, come see me at my HALO location and the staff will help us get together!

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Phoenix, Arizona.

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Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Apache Junction, AZ Mastiff in Avondale, AZ Mastiff in Buckeye, AZ Mastiff in Cave Creek, AZ Mastiff in Chandler, AZ Mastiff in El Mirage, AZ Mastiff in Fountain Hills, AZ Mastiff in Gilbert, AZ Mastiff in Glendale, AZ Mastiff in Goodyear, AZ Mastiff in Guadalupe, AZ Mastiff in Litchfield Park, AZ Mastiff in Maricopa, AZ Mastiff in Mesa, AZ Mastiff in Paradise Valley, AZ Mastiff in Peoria, AZ Mastiff in Queen Creek, AZ Mastiff in Scottsdale, AZ Mastiff in Surprise, AZ Mastiff in Tempe, AZ Mastiff in Tolleson, AZ

Related breeds in Phoenix, Arizona

Bullmastiffs in Phoenix, Arizona Neapolitan Mastiffs in Phoenix, Arizona Saint Bernards in Phoenix, Arizona

Mastiff shelters & rescues in Phoenix, Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Phoenix, Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

3.2 miles

Maricopa County Animal Care & Control West Animal Shelter

2500 S. 27th Avenue, Phoenix, AZ 85009

Pet Types: dogs

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Rescue

12.6 miles

Big Hearts for Big Breeds

Mesa, AZ 85202

Pet Types: dogs

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Shelter

13.7 miles

Maricopa County Animal Care & Control East Valley Animal Shelter

1920 S Lewis, Mesa, AZ 85210

Pet Types: dogs

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Rescue

15.2 miles

Regal Dane Rescue

4410 W UNION HILLS DR STE 7-187, GLENDALE, AZ 85308

Pet Types: dogs

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Rescue

17.9 miles

Underdog Rescue of Arizona

P.O. Box 13392, Chandler, AZ 85248

Pet Types: cats, dogs

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Rescue

18.2 miles

AZ Mastiff Rescue- English Mastiff and Other Mastiff and Giant breeds

Goodyear, AZ 85338

Pet Types: dogs

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Rescue

19.5 miles

Valley Dogs

P.O. Box 364, Gilbert, AZ 85299

Pet Types: dogs

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Shelter

29.5 miles

Central Arizona Animal Rescue

San Tan Valley, AZ 85142

Pet Types: cats, dogs, rabbits, reptiles

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Rescue

29.9 miles

Handover Rover

Scottsdale, AZ 85262

Pet Types: cats, dogs

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Shelter

45.5 miles

Pinal County Animal Care and Control

1150 S. Eleven Mile Corner Rd, Casa Grande, AZ 85194

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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