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Mastiff puppies and dogs in Phoenix, Arizona

Looking for a Mastiff puppy or dog in Phoenix, Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Phoenix, Arizona

These Mastiffs are available in Phoenix, Arizona.
We'll also keep you updated on Chewy's adoption status with email updates.
Photo of Chewy

Chewy

Mastiff

Male, 5 yrs 8 mos
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Hey there I`m Chewy!- I`m a distinguished handsome older gentleman searching for a place I can finally call home.- Sweetest big boy you’ll ever meet — a huge lover with a heart full of loyalty for my humans.- When I love, I love hard, and I’ll happily be right by your side, leaning on you and keeping you company.- Laid-back guy, also known as a couch potato- I’d prefer to be the only dog in the home- If I sound like your perfect guy come meet me and we`ll be a perfect match!*My adoption fee is sponsored by Peerless Plumbing. This means you can take me home for FREE!*No appointment necessary!25 N. 40th StPhoenix AZ 85034602-273-6852Adoption Hours:Monday - ClosedTuesday - Friday & Sunday - 11:30am - 6:00pmSaturday - 10:30am - 6:00pm.AAWL requires that all adopted dogs leave with a leash and collar and all cats leave in a carrier.
We'll also keep you updated on BLUE JAY's adoption status with email updates.
Photo of BLUE JAY

BLUE JAY

Mastiff

Male, 8 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-
We'll also keep you updated on LEDGER's adoption status with email updates.
Photo of LEDGER

LEDGER

Mastiff

Male, 2 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-
We'll also keep you updated on SABIRA's adoption status with email updates.
Photo of SABIRA

SABIRA

Mastiff

Female, 8 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Why I`d make a great companion: ~Boof! My name is Sabira and I weigh 72 LBS! ~I got my name because I always bring smiles to everyone`s faces! I`m just a sweet pup who loves affection, attention, and a nice, sniffy, moseying walk! ~Don`t be fooled, I may be big already but I`m only gonna get bigger! ~Come and visit with me today, I`m excited to meet you!Type of home I`m looking for: ~A home that can match this giants energy! ~My adoption fee is: SPONSORED BY HILL`S PET NUTRITION!
We'll also keep you updated on BROWNIE's adoption status with email updates.
Photo of BROWNIE

BROWNIE

Mastiff

Female, 5 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Why I`d make a great companion: ~Wooof! My name is Brownie and I weigh 91 LBS! ~I may look intimidating, but I’m actually a sensitive, affectionate lovebug who believes I am a lap dog! ~I can scare off strangers with my size, then immediately ask them for pets! ~Come meet me today! Type of home I`m looking for: ~I have medical disclosures for mass - removed and recent extractions. ~A loving home! ~My adoption fee is: SPONSORED BY HILL`S PET NUTRITION!
We'll also keep you updated on Moose's adoption status with email updates.
Photo of Moose

Moose

Mastiff Great Dane

Male, Young
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I rescued this sweet boy May 1st 2025 from a neglected home. At this time I had a large house with a backyard, unfortunately now I have moved out and have been traveling the country with him since early October and he has not handled life on the road very well. He needs proper kennel training and also a yard to run around in. He’s not the type for hotel rooms or small Airbnbs. He’s the best dog at dog parks, plays kindly with kids, and has never show any aggression to other animals. He is an extreme cuddle buddy and gentle giant, but it’s the time away where he struggles. He has broken out of every kennel I’ve purchased and can open nearly every door except round doorknobs. Ideal situation for him is something with a yard and even another dog to play with. I am planning on moving to Idaho once I get my condo listed for sale (will be listed on January 7th). It’s not fair for him to relocate to a smaller place where I am gone working for up to 8 hours at a time with no supervision.

Or, how about these Mastiffs in cities near Phoenix, Arizona

These Mastiffs are available for adoption close to Phoenix, Arizona.
We'll also keep you updated on Chewy's adoption status with email updates.
Photo of Chewy

Chewy

Mastiff

Male, 5 yrs 8 mos
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Hey there I`m Chewy!- I`m a distinguished handsome older gentleman searching for a place I can finally call home.- Sweetest big boy you’ll ever meet — a huge lover with a heart full of loyalty for my humans.- When I love, I love hard, and I’ll happily be right by your side, leaning on you and keeping you company.- Laid-back guy, also known as a couch potato- I’d prefer to be the only dog in the home- If I sound like your perfect guy come meet me and we`ll be a perfect match!*My adoption fee is sponsored by Peerless Plumbing. This means you can take me home for FREE!*No appointment necessary!25 N. 40th StPhoenix AZ 85034602-273-6852Adoption Hours:Monday - ClosedTuesday - Friday & Sunday - 11:30am - 6:00pmSaturday - 10:30am - 6:00pm.AAWL requires that all adopted dogs leave with a leash and collar and all cats leave in a carrier.
We'll also keep you updated on BLUE JAY's adoption status with email updates.
Photo of BLUE JAY

BLUE JAY

Mastiff

Male, 8 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-
We'll also keep you updated on LEDGER's adoption status with email updates.
Photo of LEDGER

LEDGER

Mastiff

Male, 2 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-
We'll also keep you updated on SABIRA's adoption status with email updates.
Photo of SABIRA

SABIRA

Mastiff

Female, 8 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Why I`d make a great companion: ~Boof! My name is Sabira and I weigh 72 LBS! ~I got my name because I always bring smiles to everyone`s faces! I`m just a sweet pup who loves affection, attention, and a nice, sniffy, moseying walk! ~Don`t be fooled, I may be big already but I`m only gonna get bigger! ~Come and visit with me today, I`m excited to meet you!Type of home I`m looking for: ~A home that can match this giants energy! ~My adoption fee is: SPONSORED BY HILL`S PET NUTRITION!
We'll also keep you updated on BROWNIE's adoption status with email updates.
Photo of BROWNIE

BROWNIE

Mastiff

Female, 5 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Why I`d make a great companion: ~Wooof! My name is Brownie and I weigh 91 LBS! ~I may look intimidating, but I’m actually a sensitive, affectionate lovebug who believes I am a lap dog! ~I can scare off strangers with my size, then immediately ask them for pets! ~Come meet me today! Type of home I`m looking for: ~I have medical disclosures for mass - removed and recent extractions. ~A loving home! ~My adoption fee is: SPONSORED BY HILL`S PET NUTRITION!
We'll also keep you updated on Moose's adoption status with email updates.
Photo of Moose

Moose

Mastiff Great Dane

Male, Young
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I rescued this sweet boy May 1st 2025 from a neglected home. At this time I had a large house with a backyard, unfortunately now I have moved out and have been traveling the country with him since early October and he has not handled life on the road very well. He needs proper kennel training and also a yard to run around in. He’s not the type for hotel rooms or small Airbnbs. He’s the best dog at dog parks, plays kindly with kids, and has never show any aggression to other animals. He is an extreme cuddle buddy and gentle giant, but it’s the time away where he struggles. He has broken out of every kennel I’ve purchased and can open nearly every door except round doorknobs. Ideal situation for him is something with a yard and even another dog to play with. I am planning on moving to Idaho once I get my condo listed for sale (will be listed on January 7th). It’s not fair for him to relocate to a smaller place where I am gone working for up to 8 hours at a time with no supervision.

These pups are in Phoenix, Arizona too!

Below are our newest added Mastiffs available for adoption in Phoenix, Arizona. To see more adoptable Mastiffs in Phoenix, Arizona, use the search tool below to enter specific criteria!
We'll also keep you updated on Samson's adoption status with email updates.
Photo of Samson

Samson

St. Bernard

Male, Adult
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Meet Samson , once on death row at MCACC he was rescued and has been with a foster who can longer take care of him he’s potty trained, leashed trained , at the age of 4 this sweet attentive boy is very loving. Samson has spent time with other dogs and has done fine with a calm dog and a playful dog his size or he would be great as an only dog or who likes to play ball and enjoys belly rubs and cartoons , he is very calm but will take some time to get to know you https://www.shelterluv.com/matchme/foster/BPAZ/Dog October 12, 2024, 12:18 am
We'll also keep you updated on Darla's adoption status with email updates.
Photo of Darla

Darla

St. Bernard

Female, 7 yrs 5 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
Meet Darla, a seven-year-old, 75-pound St. Bernard mix. This gentle giant had a rough start. She was found tied up outside the Maricopa County shelter for hours in the blazing June heat. Understandably, she was scared and reactive at first, but with patience and kindness, Darla has begun to show her true, affectionate self. Darla may be nervous when meeting new people, but give her a little time, and you’ll be rewarded with loyal companionship and leaning hugs that might knock you off balance (literally!). She adores scritches and pets, especially when she can press in close. Darla prefers the solo spotlight and would do best as your one-and-only pet. She walks well on a leash, is easy to handle, and would thrive in a calm, loving home where she can feel safe and appreciated. Her $150 adoption fee includes spay/neuter, vaccinations, microchip, and a free wellness visit at Phoenix Mountain Animal Hospital. To meet Darla, call 602-971-1334 or stop by Thursday–Saturday, 11am–4pm.

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Phoenix, Arizona.

Mastiff puppies and dogs in nearby cities

Related breeds in Phoenix, Arizona

Mastiff shelters & rescues in Phoenix, Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Phoenix, Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

2.6 miles

Arizona Animal Welfare League

25 N. 40th Street, Phoenix, AZ 85034

Pet Types: cats, dogs

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Shelter

3.2 miles

Maricopa County Animal Care & Control West Animal Shelter

2500 S. 27th Avenue, Phoenix, AZ 85009

Pet Types: dogs

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Shelter

4.3 miles

Arizona Humane Society - Papago Park Campus

5501 E. Van Buren Ave, Phoenix, AZ 85008

Pet Types: cats, dogs, rabbits, small animals

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Rescue

9.6 miles

FREEDOM BROTHERS RESCUE

Phoenix, AZ 85028

Pet Types: dogs

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Shelter

12.2 miles

HALO Animal Rescue

3227 E. Bell Rd., Ste D151, Phoenix, AZ 85032

Pet Types: cats, dogs

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Rescue

15.2 miles

Regal Dane Rescue

4410 W UNION HILLS DR STE 7-187, GLENDALE, AZ 85308

Pet Types: dogs

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Rescue

18 miles

Love Them All Sanctuary + Rescue

Scottsdale, AZ 85259

Pet Types: dogs

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Rescue

19.5 miles

Valley Dogs

P.O. Box 364, Gilbert, AZ 85299

Pet Types: dogs

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Rescue

29.9 miles

Handover Rover

Scottsdale, AZ 85262

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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