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Mastiff puppies and dogs in Phoenix, Arizona

Looking for a Mastiff puppy or dog in Phoenix, Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Phoenix, Arizona Other pups in Phoenix, Arizona Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Phoenix, Arizona Mastiff shelters and rescues in Phoenix, Arizona Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Phoenix, Arizona

These Mastiffs are available in Phoenix, Arizona.
Photo of Charli XCX

Charli XCX

Mastiff

Female, 1 yr 6 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Hello! I`m charli XCX- I want to give you love `365` days a year! - I will make your heart go `Boom Clap` when we play!- I am one playful gal... tug, stuffed toys, playing with other dogs, sign me up!- My playstyle with other dogs is full throttle, so I could make music with a doggy sibling who can match my vibe! - I may do well with children of all ages! - I am a weekend athlete so take me on all your adventures! No appointment necessary!**Thanks to BISSELL Pet Foundation, from July 5th through July 26th, you can take me home for FREE!**Meet me at AAWL`s Main Shelter!25 N. 40th StPhoenix AZ 85034602-273-6852Adoption Hours:Monday - ClosedTuesday - Friday & Sunday - 11:30am - 6:00pmSaturday - 10:30am - 6:00pm.AAWL requires that all adopted dogs leave with a leash and collar and all cats leave in a carrier.

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GULLY

Mastiff

Male, 3 yrs 1 mo
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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TIGGER

Mastiff

Male, 3 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-

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Later

Mastiff

Male, 2 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
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Mushu

Boxer Mastiff

Male, Young
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
House-trained, Spayed or Neutered,
Story
adoption fee is waived please call or text 6029086215 to adopt   Meet Mushu! Mushu is a Boxer/Mastiff mix born on April 9, 2025. He's a sweet, affectionate boy who loves people and thrives on attention and affection. Mushu is an indoor dog, fully housebroken, and already trained, making him a wonderful companion for the right home. While Mushu is dog-selective, he is an amazing friend to his humans and enjoys being part of the family. He's loyal, loving, and happiest when he's spending time with the people he cares about. If you're looking for a devoted companion who will reward you with endless love and friendship, Mushu could be the perfect match.  July 20, 2026, 4:50 pm

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Or, how about these Mastiffs in cities near Phoenix, Arizona

These Mastiffs are available for adoption close to Phoenix, Arizona.
Photo of Charli XCX

Charli XCX

Mastiff

Female, 1 yr 6 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Hello! I`m charli XCX- I want to give you love `365` days a year! - I will make your heart go `Boom Clap` when we play!- I am one playful gal... tug, stuffed toys, playing with other dogs, sign me up!- My playstyle with other dogs is full throttle, so I could make music with a doggy sibling who can match my vibe! - I may do well with children of all ages! - I am a weekend athlete so take me on all your adventures! No appointment necessary!**Thanks to BISSELL Pet Foundation, from July 5th through July 26th, you can take me home for FREE!**Meet me at AAWL`s Main Shelter!25 N. 40th StPhoenix AZ 85034602-273-6852Adoption Hours:Monday - ClosedTuesday - Friday & Sunday - 11:30am - 6:00pmSaturday - 10:30am - 6:00pm.AAWL requires that all adopted dogs leave with a leash and collar and all cats leave in a carrier.

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Photo of GULLY

GULLY

Mastiff

Male, 3 yrs 1 mo
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-

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Photo of TIGGER

TIGGER

Mastiff

Male, 3 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-

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Photo of Later

Later

Mastiff

Male, 2 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-

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Photo of Fern

Fern

English Mastiff Irish Wolfhound

Female, Adult
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Fern is a five-year-old Irish Wolfhound, Great Dane, and Mastiff mix with the sweetest sugary face and a personality to match. This one-of-a-kind girl is the kind of dog who makes everyone she meets smile, effortlessly winning hearts with her gentle nature and loving spirit. Now in the care of Big Hearts for Big Breeds, Fern has shown herself to be an absolute treasure. She is wonderful with other dogs, great with cats, and loves kids, making her the kind of companion who fits beautifully into a variety of family dynamics. Whether she's making new friends or simply enjoying quiet time with her people, Fern brings warmth and joy wherever she goes. With her unique blend of giant breeds comes an equally giant heart. She’s affectionate without being demanding, sweet without trying, and has the kind of calm presence that makes every day a little brighter. Her soulful eyes and sugar-dusted face tell the story of a dog who is simply happy to be loved and to love in return. If you've been searching for a loyal best friend who gets along with everyone and has enough love to fill an entire home, Fern may be exactly the companion you've been waiting for. Big Hearts for Big Breeds can't wait to see this special girl find the forever family she so richly deserves.

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Photo of Janice

Janice

English Mastiff

Female, Young
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Janice is a female Mastiff mix pup who recently joined the Big Hearts for Big Breeds crew. She's got the kind of sweet face that instantly melts hearts! Janice is another sibling from the beloved “Friends” foster pups, and she’s already showing what a special girl she is. Playful and curious, Janice is settling right into her new foster home and learning the ropes alongside other large dogs. She enjoys playtime, companionship, and is gaining confidence every day as she adapts to her new surroundings. With her loving nature and easygoing personality, Janice is ready to grow into a wonderful companion for a family who will continue guiding her, loving her, and cheering her on as she blossoms.

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These pups are in Phoenix, Arizona too!

Below are our newest added Mastiffs available for adoption in Phoenix, Arizona. To see more adoptable Mastiffs in Phoenix, Arizona, use the search tool below to enter specific criteria!
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Photo of WINIFRED

WINIFRED

St. Bernard

Female, 2 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-

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Photo of Darla

Darla

St. Bernard

Female, 7 yrs 11 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
Meet Darla, a seven-year-old, 75-pound St. Bernard mix. This gentle giant had a rough start. She was found tied up outside the Maricopa County shelter for hours in the blazing June heat. Understandably, she was scared and reactive at first, but with patience and kindness, Darla has begun to show her true, affectionate self. Darla may be nervous when meeting new people, but give her a little time, and you’ll be rewarded with loyal companionship and leaning hugs that might knock you off balance (literally!). She adores scritches and pets, especially when she can press in close. Darla prefers the solo spotlight and would do best as your one-and-only pet. She walks well on a leash, is easy to handle, and would thrive in a calm, loving home where she can feel safe and appreciated. Her $150 adoption fee includes spay/neuter, vaccinations, microchip, and a free wellness visit at Phoenix Mountain Animal Hospital. To meet Darla, call 602-971-1334 or stop by Thursday–Saturday, 11am–4pm.

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Photo of Atlas 2

Atlas 2

St. Bernard

Male, 1 yr
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Phoenix, Arizona.

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Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Apache Junction, AZ Mastiff in Avondale, AZ Mastiff in Buckeye, AZ Mastiff in Cave Creek, AZ Mastiff in Chandler, AZ Mastiff in El Mirage, AZ Mastiff in Fountain Hills, AZ Mastiff in Gilbert, AZ Mastiff in Glendale, AZ Mastiff in Goodyear, AZ Mastiff in Guadalupe, AZ Mastiff in Litchfield Park, AZ Mastiff in Maricopa, AZ Mastiff in Mesa, AZ Mastiff in Paradise Valley, AZ Mastiff in Peoria, AZ Mastiff in Queen Creek, AZ Mastiff in Scottsdale, AZ Mastiff in Surprise, AZ Mastiff in Tempe, AZ Mastiff in Tolleson, AZ

Related breeds in Phoenix, Arizona

Bullmastiffs in Phoenix, Arizona Neapolitan Mastiffs in Phoenix, Arizona Saint Bernards in Phoenix, Arizona

Mastiff shelters & rescues in Phoenix, Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Phoenix, Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

2.6 miles

Arizona Animal Welfare League

25 N. 40th Street, Phoenix, AZ 85034

Pet Types: cats, dogs

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Shelter

3.2 miles

Maricopa County Animal Care & Control West Animal Shelter

2500 S. 27th Avenue, Phoenix, AZ 85009

Pet Types: dogs

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Rescue

9.6 miles

HARTT

Phoenix, AZ 85028

Pet Types: cats, dogs

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Rescue

12.6 miles

Big Hearts for Big Breeds

Mesa, AZ 85202

Pet Types: dogs

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Rescue

13.2 miles

Desert Dog Project

Scottsdale, AZ 85254

Pet Types: dogs

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Shelter

13.7 miles

Maricopa County Animal Care & Control East Valley Animal Shelter

1920 S Lewis, Mesa, AZ 85210

Pet Types: dogs

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Rescue

15.2 miles

Regal Dane Rescue

4410 W UNION HILLS DR STE 7-187, GLENDALE, AZ 85308

Pet Types: dogs

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Rescue

17.9 miles

Underdog Rescue of Arizona

P.O. Box 13392, Chandler, AZ 85248

Pet Types: cats, dogs

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Rescue

18.2 miles

AZ Mastiff Rescue- English Mastiff and Other Mastiff and Giant breeds

Goodyear, AZ 85338

Pet Types: dogs

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Rescue

19.5 miles

Valley Dogs

P.O. Box 364, Gilbert, AZ 85299

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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