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Mastiff puppies and dogs in Phoenix, Arizona

Looking for a Mastiff puppy or dog in Phoenix, Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Phoenix, Arizona

These Mastiffs are available in Phoenix, Arizona.
We'll also keep you updated on BLUE JAY's adoption status with email updates.
Photo of BLUE JAY

BLUE JAY

Mastiff

Male, 8 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
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We'll also keep you updated on Hazel's adoption status with email updates.
Photo of Hazel

Hazel

Mastiff Weimaraner

Female, 1 yr 6 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Hazel — a big girl with an even bigger heart! Hazel recently joined our rescue from Holbrook Animal Care and Control. Since being in our care, she’s quickly won over volunteer’s hearts with her sweet and goofy personality. Hazel is fine tuning her leash manners but enjoys her daily walks with volunteers. She knows basic commands and would love to continue to learn. Hazel is super playful and loves toys. This girl is super sweet and loves affection. Hazel just wants a person to love and a home to relax in. Can you be the one to give it to her?
We'll also keep you updated on Moose's adoption status with email updates.
Photo of Moose

Moose

Mastiff Great Dane

Male, Young
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I rescued this sweet boy May 1st 2025 from a neglected home. At this time I had a large house with a backyard, unfortunately now I have moved out and have been traveling the country with him since early October and he has not handled life on the road very well. He needs proper kennel training and also a yard to run around in. He’s not the type for hotel rooms or small Airbnbs. He’s the best dog at dog parks, plays kindly with kids, and has never show any aggression to other animals. He is an extreme cuddle buddy and gentle giant, but it’s the time away where he struggles. He has broken out of every kennel I’ve purchased and can open nearly every door except round doorknobs. Ideal situation for him is something with a yard and even another dog to play with. I am planning on moving to Idaho once I get my condo listed for sale (will be listed on January 7th). It’s not fair for him to relocate to a smaller place where I am gone working for up to 8 hours at a time with no supervision.
We'll also keep you updated on Hulk's adoption status with email updates.
Photo of Hulk

Hulk

Mastiff Cane Corso

Male, 3 yrs 9 mos
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
💚 Gentle Giant Hulk 💚 Meet Hulk, a 2-year-old Mastiff. Despite his big name and size, Hulk is more of a shy, sensitive soul than a superhero. But with time, patience, and calm handling, Hulk shows he can tolerate gentle pets and slowly build trust. What makes Hulk special 💪 Big, handsome Mastiff boy 💚 Sensitive and gentle-natured despite his size 🐾 Looking for a safe space to relax and rebuild confidence What Hulk needs 🕰️ Extra patience and time to decompress 🏡 A calm, structured environment without pressure 🤝 A kind person who can help him come out of his shell
We'll also keep you updated on Zeus's adoption status with email updates.
Photo of Zeus

Zeus

Mastiff

Male, 1 yr
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-

Or, how about these Mastiffs in cities near Phoenix, Arizona

These Mastiffs are available for adoption close to Phoenix, Arizona.
We'll also keep you updated on BLUE JAY's adoption status with email updates.
Photo of BLUE JAY

BLUE JAY

Mastiff

Male, 8 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-
We'll also keep you updated on Hazel's adoption status with email updates.
Photo of Hazel

Hazel

Mastiff Weimaraner

Female, 1 yr 6 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet Hazel — a big girl with an even bigger heart! Hazel recently joined our rescue from Holbrook Animal Care and Control. Since being in our care, she’s quickly won over volunteer’s hearts with her sweet and goofy personality. Hazel is fine tuning her leash manners but enjoys her daily walks with volunteers. She knows basic commands and would love to continue to learn. Hazel is super playful and loves toys. This girl is super sweet and loves affection. Hazel just wants a person to love and a home to relax in. Can you be the one to give it to her?
We'll also keep you updated on Moose's adoption status with email updates.
Photo of Moose

Moose

Mastiff Great Dane

Male, Young
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I rescued this sweet boy May 1st 2025 from a neglected home. At this time I had a large house with a backyard, unfortunately now I have moved out and have been traveling the country with him since early October and he has not handled life on the road very well. He needs proper kennel training and also a yard to run around in. He’s not the type for hotel rooms or small Airbnbs. He’s the best dog at dog parks, plays kindly with kids, and has never show any aggression to other animals. He is an extreme cuddle buddy and gentle giant, but it’s the time away where he struggles. He has broken out of every kennel I’ve purchased and can open nearly every door except round doorknobs. Ideal situation for him is something with a yard and even another dog to play with. I am planning on moving to Idaho once I get my condo listed for sale (will be listed on January 7th). It’s not fair for him to relocate to a smaller place where I am gone working for up to 8 hours at a time with no supervision.
We'll also keep you updated on Hulk's adoption status with email updates.
Photo of Hulk

Hulk

Mastiff Cane Corso

Male, 3 yrs 9 mos
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Spayed or Neutered,
Story
💚 Gentle Giant Hulk 💚 Meet Hulk, a 2-year-old Mastiff. Despite his big name and size, Hulk is more of a shy, sensitive soul than a superhero. But with time, patience, and calm handling, Hulk shows he can tolerate gentle pets and slowly build trust. What makes Hulk special 💪 Big, handsome Mastiff boy 💚 Sensitive and gentle-natured despite his size 🐾 Looking for a safe space to relax and rebuild confidence What Hulk needs 🕰️ Extra patience and time to decompress 🏡 A calm, structured environment without pressure 🤝 A kind person who can help him come out of his shell
We'll also keep you updated on Zeus's adoption status with email updates.
Photo of Zeus

Zeus

Mastiff

Male, 1 yr
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
-
We'll also keep you updated on Apollo's adoption status with email updates.
Photo of Apollo

Apollo

Mastiff Great Dane

Male, Adult
GLENDALE, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I'm a strong and active boy who thinks I'm a lap dog. I get excited when it's time to go on walks, but then once we're walking, I'm calm. I do get excited when I meet kids, but after I will calm down and I leave them alone, unless they keep playing with me. Little kids might be afraid of me because of my size and run away from me and I think that they want to play, so just watch them. I would do best in a home with older children. My best day would be to: Going for a car ride to a park to go for a walk and then come home and nap. Other tidbits about me: I do fine being left out to roam the house when no one is home, because all I do is lay on the couch. I like being introduced to other dogs slowly and properly, otherwise I get over-excited. If, when I first meet new people and they have sunglasses on, I can get scared. As I am a pretty big boy, I can be strong when I get excited, so you need to be ready if you have the leash. I am not really interested in toys, but there are times when I do get the urge. I do slobber, so make sure to keep towels around.

These pups are in Phoenix, Arizona too!

Below are our newest added Mastiffs available for adoption in Phoenix, Arizona. To see more adoptable Mastiffs in Phoenix, Arizona, use the search tool below to enter specific criteria!
We'll also keep you updated on Samson's adoption status with email updates.
Photo of Samson

Samson

St. Bernard

Male, Adult
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Meet Samson , once on death row at MCACC he was rescued and has been with a foster who can longer take care of him he’s potty trained, leashed trained , at the age of 4 this sweet attentive boy is very loving. Samson has spent time with other dogs and has done fine with a calm dog and a playful dog his size or he would be great as an only dog or who likes to play ball and enjoys belly rubs and cartoons , he is very calm but will take some time to get to know you https://www.shelterluv.com/matchme/foster/BPAZ/Dog October 12, 2024, 12:18 am
We'll also keep you updated on Apollo's adoption status with email updates.
Photo of Apollo

Apollo

Bullmastiff American Bulldog

Male, Adult
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Apollo is a very sweet and mild-mannered dog. He is not a barker unless he senses danger close by. He sleeps a ton, as most bully breeds do. He is house trained and is great wish people and kids. Apollo does require ear cleaning once a week which is a very simple 3 minute job. He loves walks and affection. He needs a bath once a week with a special shampoo (which we purchase on amazon) or he will begin to get itchy. The only other thing is he gets anxious with fireworks and does not like to be left alone during fireworks. My wife and were promoted in our jobs and do not have the time to give him the attention that he needs and deserves. He truly is a wonderful dog. We rescued him last year and hate to rehome him but we want him to have a better life. If you meet him once, you will love him.
We'll also keep you updated on Darla's adoption status with email updates.
Photo of Darla

Darla

St. Bernard

Female, 7 yrs 5 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with dogs, Spayed or Neutered, Shots are up-to-date,
Story
Meet Darla, a seven-year-old, 75-pound St. Bernard mix. This gentle giant had a rough start. She was found tied up outside the Maricopa County shelter for hours in the blazing June heat. Understandably, she was scared and reactive at first, but with patience and kindness, Darla has begun to show her true, affectionate self. Darla may be nervous when meeting new people, but give her a little time, and you’ll be rewarded with loyal companionship and leaning hugs that might knock you off balance (literally!). She adores scritches and pets, especially when she can press in close. Darla prefers the solo spotlight and would do best as your one-and-only pet. She walks well on a leash, is easy to handle, and would thrive in a calm, loving home where she can feel safe and appreciated. Her $150 adoption fee includes spay/neuter, vaccinations, microchip, and a free wellness visit at Phoenix Mountain Animal Hospital. To meet Darla, call 602-971-1334 or stop by Thursday–Saturday, 11am–4pm.

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Phoenix, Arizona.

Mastiff puppies and dogs in nearby cities

Related breeds in Phoenix, Arizona

Mastiff shelters & rescues in Phoenix, Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Phoenix, Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

3.2 miles

Maricopa County Animal Care & Control West Animal Shelter

2500 S. 27th Avenue, Phoenix, AZ 85009

Pet Types: dogs

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Rescue

4.3 miles

Alone No More Dog Rescue

Phoenix, AZ 85008

Pet Types: dogs

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Rescue

9.6 miles

FREEDOM BROTHERS RESCUE

Phoenix, AZ 85028

Pet Types: dogs

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Shelter

12.2 miles

HALO Animal Rescue

3227 E. Bell Rd., Ste D151, Phoenix, AZ 85032

Pet Types: cats, dogs

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Rescue

15.2 miles

Regal Dane Rescue

4410 W UNION HILLS DR STE 7-187, GLENDALE, AZ 85308

Pet Types: dogs

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Rescue

18 miles

Love Them All Sanctuary + Rescue

Scottsdale, AZ 85259

Pet Types: dogs

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Rescue

19.5 miles

Valley Dogs

P.O. Box 364, Gilbert, AZ 85299

Pet Types: dogs

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Rescue

29.9 miles

Handover Rover

Scottsdale, AZ 85262

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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