Mastiff Adoption in Tempe, AZ: Mastiff Puppies for Sale in Tempe, AZ

Adopt a Mastiff near you in Tempe, Arizona

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Tempe, Arizona

These Mastiffs are available for adoption close to Tempe, Arizona.

MONA

Mastiff

Female, 5 yrs

Phoenix, AZ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Spayed or Neutered,

Story

Why I`d make a great companion: ~Woof! My name is Mona and I weigh 79 LBS! ~I’ve got plenty of love to give and would love nothing more than a family to call my own. ~If you’re looking for a big girl with a big personality and an even bigger heart, I might just be your perfect match! ~Come on down to meet me today!Type of home I`m looking for: ~Someone ready for a loyal companion who will be by their side through thick and thin. ~My adoption fee is: SPONSORED BY HILLS PET NUTRITION!

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Sky

English Mastiff Great Dane

Female, Adult

Mesa, AZ

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Spayed or Neutered,

Story

Sky is a six-year-old Great Dane and Mastiff mix with a gentle heart, an easygoing personality, and a smile that's sure to brighten your day. Now in the care of Big Hearts for Big Breeds, this sweet girl is ready to find the forever family she's been waiting for. Sky is wonderful with people, great with kids, and gets along beautifully with both large and small dogs. Her compatibility with cats is currently unknown as we continue learning more about her. Whether she's making new friends or relaxing by your side, Sky has a calm, affectionate nature that makes her an easy dog to love. She is kennel trained, potty trained, and has excellent house manners. Sky enjoys going for walks, though she can pull a bit on leash and will benefit from continued practice to polish her manners. When it's time to play, tug-of-war is one of her favorite games, and she's always happy to join in on a little friendly fun before settling in for cuddles. Sky will also be undergoing cherry eye surgery while in the care of Big Hearts for Big Breeds, ensuring she receives the veterinary care she needs before beginning the next chapter of her life. With her sweet disposition, playful spirit, and loving personality, Sky is the kind of dog who fits naturally into family life. If you're looking for a loyal companion who enjoys both playtime and quiet moments, Sky may be the perfect addition to your home. Big Hearts for Big Breeds can't wait to help this wonderful girl find the loving forever family she deserves.

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Janice

English Mastiff

Female, Young

Mesa, AZ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,

Story

Janice is a female Mastiff mix pup who recently joined the Big Hearts for Big Breeds crew. She's got the kind of sweet face that instantly melts hearts! Janice is another sibling from the beloved “Friends” foster pups, and she’s already showing what a special girl she is. Playful and curious, Janice is settling right into her new foster home and learning the ropes alongside other large dogs. She enjoys playtime, companionship, and is gaining confidence every day as she adapts to her new surroundings. With her loving nature and easygoing personality, Janice is ready to grow into a wonderful companion for a family who will continue guiding her, loving her, and cheering her on as she blossoms.

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Maple

English Mastiff

Female, Young

Mesa, AZ

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with dogs, Good with cats, House-trained, Spayed or Neutered,

Story

Maple is a one-year-old Mastiff mix who may be petite in size, but she’s overflowing with personality, playfulness, and charm. Now in the care of Big Hearts for Big Breeds, this sweet young girl is ready to find a forever family to grow up with. Maple is the sibling of some familiar Big Hearts faces—the beloved “Friends” crew, Rachel, Monica, Phoebe, and Janice—but she’s just beginning her own rescue journey. Like her siblings, she is shy and timid at first, but she truly has a loving heart and is eager to make lasting connections with the people around her. Still very much a puppy, Maple loves to play and brings a fun, energetic spirit wherever she goes. She does well with other dogs and was around cats when she was younger, giving her a solid foundation as she continues to learn and mature. With continued guidance, socialization, and plenty of positive experiences, she’s sure to blossom into an incredible companion. Maple is looking for a family that will embrace her youthful enthusiasm, celebrate her milestones, and give her all the love she deserves. If you’re searching for a playful, affectionate best friend with a bright future ahead, Maple might just be the perfect addition to your home.

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Dr Dre

English Mastiff Great Dane

Male, Adult

Mesa, AZ

Size

(when grown) -

Details

Spayed or Neutered,

Story

Dr Dre is a five-year-old Great Dane/Mastiff mix with a big heart, a big personality, and a whole lot of love to give. Just over a year ago, Dre found a family of his own, but sometimes life changes and circumstances shift. Through no fault of his own, Dre has found himself back with Big Hearts for Big Breeds, and we’re committed to helping him find the right forever home this time around. So, what do we know about Dre? He’s great with other dogs, wonderful with kids, and absolutely loves his people. Dre is the kind of dog who loves hard, plays hard, and will keep you laughing with his goofy personality. And when the fun is over, he’s happiest curled up beside the people he loves. Dre isn’t a “problem dog.” He’s a dog who thrives with leadership. He wants someone he can trust—someone who can provide consistency, confidence, clear expectations, and kind guidance. When Dre has that structure, he shines. He doesn't want to be in charge; he wants to know that someone he trusts has things handled. The good news? Dre comes with an incredible foundation of training. His trainer has invested in helping him become the best version of himself and is committed to supporting his future foster or adopter with follow-up training sessions. His next family won't be navigating this journey alone. Dre is looking for someone who understands the responsibility and rewards of living with a giant-breed dog and is ready to continue the structure that helps him succeed. Give him the leadership he needs, the consistency he craves, and the love he so freely gives, and you'll have one incredibly devoted companion by your side. Sometimes the second chance is the one that finally sticks. Dre is ready for his.

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Charli XCX

Mastiff

Female, 1 yr 7 mos

Phoenix, AZ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Hello! I`m charli XCX- I want to give you love `365` days a year! - I will make your heart go `Boom Clap` when we play!- I am one playful gal... tug, stuffed toys, playing with other dogs, sign me up!- My playstyle with other dogs is full throttle, so I could make music with a doggy sibling who can match my vibe! - I may do well with children of all ages! - I am a weekend athlete so take me on all your adventures! No appointment necessary!Meet me at AAWL`s Main Shelter!25 N. 40th StPhoenix AZ 85034602-273-6852Adoption Hours:Monday - ClosedTuesday - Friday & Sunday - 11:30am - 6:00pmSaturday - 10:30am - 6:00pm.AAWL requires that all adopted dogs leave with a leash and collar and all cats leave in a carrier.

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Mastiff puppies and dogs in Tempe, Arizona

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Mastiff puppies and dogs in Tempe, Arizona

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Adopt a Mastiff near you in Tempe, Arizona

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Tempe, Arizona

These Mastiffs are available for adoption close to Tempe, Arizona.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Tempe, Arizona

Mastiff shelters & rescues in Tempe, Arizona

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics