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Mastiff puppies and dogs in Arizona

Looking for a Mastiff puppy or dog in Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Arizona

Below are our newest added Mastiffs available for adoption in Arizona. To see more adoptable Mastiffs in Arizona, use the search tool below to enter specific criteria!
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ZACHARY

Mastiff

Male, 3 yrs
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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TOYOTA

Mastiff/Great Dane

Male, 3 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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No photo available for Onyx

Onyx

Mastiff

Male, Young
Goodyear, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
You can fill out an adoption application online on our official website.More info to come!Visit this organization's web site to see any additional information available about this pet.October 30, 2026, 2:07 pm
Photo of Bear

Bear

Mastiff/Bull Terrier

Male, Adult
Prescott Valley, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Bear is a great loving dog. He let's you know when he wants outside to potty. He likes to cuddle and take naps.
Photo of Sully

Sully

Mastiff

Male, Young
Goodyear, AZ
Size
(when grown) -
Details
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Story
You can fill out an adoption application online on our official website.Sully MEET SULLY — OUR SWEET YOUNG CANE CORSO! Meet Sully, a handsome black Cane Corso boy, approximately 8 months to 1 year old, with a heart of gold! ❤️ Sully and his sister were abandoned in the desert. Thankfully, HARTT was able to trap Sully and bring him to safety after someone took his sister home. Despite his rough start, Sully is an incredibly sweet, social, dog-friendly, and people-loving boy who just wants to please and be loved! He LOVES playgroup, especially chasing his buddies Diamond and Beauty around the yard. His favorite game is King of the Mountain, where he gets all his friends to chase him! And when playtime is over, he’s always ready for cuddles. When Sully first arrived, he was terrified to go outside and wanted to run straight back to his kennel. Now he’s gaining confidence, enjoying the outdoors, and learning that life can be wonderful! ❤️ Sully may not be the biggest or most traditional-looking Corso, but his personality more than makes up for it! We think he’d make a wonderful family companion. Like any young Corso, he’ll benefit from basic training, routine, structure, and a family committed to helping him continue to blossom. Sully survived being abandoned. Now he deserves a family who will never leave him behind. Visit this organization's web site to see any additional information available about this pet.October 30, 2026, 2:07 pm
Photo of Winnie

Winnie

Mastiff

Female, Puppy
Goodyear, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats,
Story
You can fill out an adoption application online on our official website. MEET WINNIE! 13 Weeks Old | Female Mastiff Mix | Sweet as Can Be! ❤️ Looking for a sweet, affectionate puppy to add to your family? Meet our adorable little Winnie! Winnie is a 13-week-old Mastiff mix with a gentle, sweet personality and a whole lot of love to give! This little girl can be a little shy when first meeting new people, but give her a little time to warm up, and you’ll discover what an affectionate sweetheart she really is! She loves attention, enjoys being loved on, and especially seems to have a soft spot for men! ❤️ Winnie is dog friendly, cat friendly, and kid friendly! She’s still a baby, learning all about the big world around her. A Little More About Winnie: 13-week-old female Mastiff mix Very dog friendly Cat friendly Kid friendly ❤️ A little shy initially, but very affectionate once comfortable Absolutely loves men! Working on house training Sweet, gentle, and still learning about life! Winnie’s ideal home MUST have another dog! Having a four-legged companion will help Winnie build her confidence as she grows. She needs a doggy friend to play with, learn from, and help show her that the world isn’t such a scary place. We would love to see Winnie in a patient, loving home where she can continue to blossom at her own pace. She’s just a baby and will need guidance, continued training, and lots of positive experiences. With a little patience, a doggy best friend, and a whole lot of love, this sweet girl is going to make someone an amazing companion! ❤️ Who has room in their home and heart for little Winnie? AZ Mastiff Rescue www.azmastiffrescue.com ❤️ Rescue One Until There Are None ❤️ #AZMastiffRescue #PACC911Partner #AdoptWinnie #MastiffMix #MastiffPuppy #RescuePuppy #AdoptDontShop #GiantBreedRescue #RescueOneUntilThereAreNone  Visit this organization's web site to see any additional information available about this pet.October 30, 2026, 2:07 pm

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Arizona.

Mastiff puppies and dogs in Arizona cities

Mastiff shelters & rescues in Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Shelter

Humane Society of Southern Arizona

635 W. Roger Rd., Tucson , AZ 85705

Pet Types: cats, birds, dogs, farm animals, rabbits, small animals

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Shelter

Pima Animal Care Center

4000 N. Silverbell Road, Tucson , AZ 85745

Pet Types: cats, dogs, rabbits, small animals

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Shelter

Paws Without Borders

4115 East Lester Street, Tucson , AZ 85712

Pet Types: dogs

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Shelter

Pinal County Animal Care and Control

1150 S. Eleven Mile Corner Rd, Casa Grande , AZ 85194

Pet Types: cats, dogs

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Shelter

Central Arizona Animal Rescue

San Tan Valley , AZ 85142

Pet Types: cats, dogs, rabbits, reptiles

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Rescue

Underdog Rescue of Arizona

P.O. Box 13392, Chandler , AZ 85248

Pet Types: cats, dogs

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Rescue

Valley Dogs

P.O. Box 364, Gilbert , AZ 85299

Pet Types: dogs

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Rescue

Big Hearts for Big Breeds

Mesa , AZ 85202

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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