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Mastiff puppies and dogs in Arizona

Looking for a Mastiff puppy or dog in Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff in Arizona Search for a Mastiff puppy or dog Mastiff puppies and dogs in Arizona cities Mastiff shelters and rescues in Arizona Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Arizona

Below are our newest added Mastiffs available for adoption in Arizona. To see more adoptable Mastiffs in Arizona, use the search tool below to enter specific criteria!
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No photo available for Griffith

Griffith

Mastiff

Male, Puppy
Goodyear, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained,
Story
You can fill out an adoption application online on our official website.Meet Griffith   Griffith is a 5–6 month old Mastiff mix puppy and truly one of the sweetest little boys ever. This adorable guy is very dog friendly, kid friendly, crate trained, and already has great house manners.   He loves to play, enjoys water, toys, and bully sticks, and is just waiting for the chance to be someone’s beloved pet. Griffith definitely needs a home with another dog so he can have a buddy to play with and learn from.   Someone is going to get an absolute gem with this boy.   AZ Mastiff Rescue azmastiffrescue.com   #AZMastiffRescue #AdoptGriffith #MastiffMix #PuppyLove #RescuePuppy #DogFriendly #KidFriendly #AdoptDontShop #RescueDogsRock #ForeverHomeNeeded #ArizonaDogs #MastiffRescueVisit this organization's web site to see any additional information available about this pet.May 17, 2026, 8:05 am

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Maple

English Mastiff

Female, Young
Mesa, AZ
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, Good with cats, House-trained,
Story
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Everest

English Mastiff/Great Dane

Male, Adult
Mesa, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, House-trained,
Story
Everest is a two-year-old Great Dane/Mastiff mix who has already made a big impression at Big Hearts for Big Breeds. With his big blocky head and soft, expressive face, this sweet boy absolutely melts into a puddle the moment he’s getting affection. Everest is a gentle, submissive soul who leans into love and enjoys being close to his people. While we’re still getting to know him, he is already showing that he does well with other dogs and has a calm, easygoing nature that makes him a joy to be around. As Everest settles into rescue, we’re excited to continue learning more about him and watching his personality unfold. What’s already clear is that he’s a kind-hearted, affectionate dog who is ready for a home where he can feel safe, loved, and part of the family. If you’re looking for a big, soft-hearted companion who just wants to love and be loved, Everest may be your perfect match.

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Janice

English Mastiff

Female, Young
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Janice is a female Mastiff mix pup who recently joined the Big Hearts for Big Breeds crew. She's got the kind of sweet face that instantly melts hearts! Janice is another sibling from the beloved “Friends” foster pups, and she’s already showing what a special girl she is. Playful and curious, Janice is settling right into her new foster home and learning the ropes alongside other large dogs. She enjoys playtime, companionship, and is gaining confidence every day as she adapts to her new surroundings. With her loving nature and easygoing personality, Janice is ready to grow into a wonderful companion for a family who will continue guiding her, loving her, and cheering her on as she blossoms.

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Photo of Slate

Slate

English Mastiff

Male, Young
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, House-trained,
Story
Slate is a young male Mastiff mix, under a year old, who is just getting started on his journey with Big Hearts for Big Breeds. With his growing size and playful spirit, this handsome pup is full of potential and ready to learn what life as a loved family dog is all about. Slate is kennel trained and has already shown that he does well with other dogs. Like many young pups, he’s full of energy, curiosity, and that fun-loving personality that keeps life interesting. He’s still learning the ropes, so he’ll benefit from a home that’s committed to helping him build good manners, strong social skills, and confidence as he matures. With consistency, guidance, and plenty of positive experiences, Slate is going to grow into an incredible companion. He’s looking for a family that’s ready to invest in his future and enjoy the journey of raising a big, lovable dog. If you’re ready for puppy energy, training wins, and a loyal best friend in the making, Slate may be the perfect addition to your home.

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Caine

Mastiff/German Shepherd Dog

Male, Adult
Lake Havasu City, AZ
Size
(when grown) -
Details
-
Story
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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Arizona.

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Mastiff puppies and dogs in Arizona cities

Mastiff Puppies near me Mastiff in Apache Junction Mastiff in Avondale Mastiff in Benson Mastiff in Bisbee Mastiff in Buckeye Mastiff in Bullhead City Mastiff in Camp Verde Mastiff in Casa Grande Mastiff in Cave Creek Mastiff in Chandler Mastiff in Chino Valley Mastiff in Colorado City Mastiff in Coolidge Mastiff in Cottonwood Mastiff in Douglas Mastiff in Eagar Mastiff in El Mirage Mastiff in Eloy Mastiff in Flagstaff Mastiff in Florence Mastiff in Fountain Hills Mastiff in Gilbert Mastiff in Glendale Mastiff in Globe Mastiff in Goodyear Mastiff in Guadalupe Mastiff in Holbrook Mastiff in Kingman Mastiff in Lake Havasu City Mastiff in Litchfield Park Mastiff in Marana Mastiff in Maricopa Mastiff in Mesa Mastiff in Nogales Mastiff in Oro Valley Mastiff in Page Mastiff in Paradise Valley Mastiff in Payson Mastiff in Peoria Mastiff in Phoenix Mastiff in Pinetop Mastiff in Prescott Mastiff in Prescott Valley Mastiff in Queen Creek Mastiff in Safford Mastiff in Sahuarita Mastiff in San Luis Mastiff in Scottsdale Mastiff in Sedona Mastiff in Show Low Mastiff in Sierra Vista Mastiff in Snowflake Mastiff in Somerton Mastiff in South Tucson Mastiff in Surprise Mastiff in Tempe Mastiff in Thatcher Mastiff in Tolleson Mastiff in Tucson Mastiff in Wickenburg Mastiff in Winslow Mastiff in Youngtown Mastiff in Yuma

Mastiff shelters & rescues in Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Ghost Town Dog Rescue

Mesa , AZ 85213

Pet Types: dogs

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Rescue

Desert Dog Project

Scottsdale , AZ 85254

Pet Types: dogs

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Rescue

Handover Rover

Scottsdale , AZ 85262

Pet Types: cats, dogs

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Shelter

Maricopa County Animal Care & Control East Valley Animal Shelter

1920 S Lewis, Mesa , AZ 85210

Pet Types: dogs

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Rescue

Arf-Anage Dog Rescue

Phoenix , AZ 85032

Pet Types: dogs

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Rescue

Big Hearts for Big Breeds

Mesa , AZ 85202

Pet Types: dogs

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Rescue

Valley Dogs

P.O. Box 364, Gilbert , AZ 85299

Pet Types: dogs

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Shelter

Maricopa County Animal Care & Control West Animal Shelter

2500 S. 27th Avenue, Phoenix , AZ 85009

Pet Types: dogs

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Rescue

Regal Dane Rescue

4410 W UNION HILLS DR STE 7-187, GLENDALE , AZ 85308

Pet Types: dogs

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Rescue

Underdog Rescue of Arizona

P.O. Box 13392, Chandler , AZ 85248

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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