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Mastiff puppies and dogs in Arizona

Looking for a Mastiff puppy or dog in Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Arizona

Below are our newest added Mastiffs available for adoption in Arizona. To see more adoptable Mastiffs in Arizona, use the search tool below to enter specific criteria!
We'll also keep you updated on DEBRA's adoption status with email updates.
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DEBRA

Mastiff/Husky

Female, 1 yr
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Why I`d make a great companion: ~Wooof! My name is Debra and I weigh 49 LBS! ~I have a giant body and a soft, gentle heart! ~I grew up in a home with lots of other dogs, so I didn’t get much one-on-one attention or chances to experience everyday things yet, but I`m eager to learn and spend time in the outside world so please be patient with me! ~Underneath this build, is a sensitive, very sweet lady ready to show her loving side! ~Come down and say hello to me today! Type of home I`m looking for: ~A patient and kind home that understands to go slow with me and help me build my confidence! ~I have to meet all children in my future home before adoption. ~My adoption fee is: $99
We'll also keep you updated on Mojo's adoption status with email updates.
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Photo of Mojo

Mojo

Mastiff

Male, Young
Goodyear, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs,
Story
You can fill out an adoption application online on our official website.Meet Mojo   Mojo came into rescue with his brother Monte after both boys found themselves in a shelter in San Bernardino. Sadly, they both came down with pneumonia and were placed on the E-list. Thankfully they made it out in time and are now safe with us.   Now that Mojo is healthy, he’s ready for the next step — his cherry eye surgery and neuter — and then he’ll be ready to find his forever home.   Mojo is the more outgoing of the two brothers. He loves going for walks, enjoys toys, and is always happy to cuddle up with his people. He’s dog friendly and does best with female dogs. Mojo has a fun, loving personality and is the kind of dog who will happily join you on adventures and then curl up for snuggles afterward.   If you’re looking for a loyal companion with a playful side and a big heart, Mojo might be your guy.   Put in your application and come meet Mojo — you might just meet your next best friend.   Az Mastiff Rescue www.azmastiffrescue.com   #azmastiffrescue #adoptdontshop #mastiffrescue #rescuedog #mastifflove #bigdogsofinstagram #adoptmastiff #rescuedismyfavoritebreed #dogrescue #foreverhomewanted #mastiffmix #doglover #rescueismyfavoritebreed  Visit this organization's web site to see any additional information available about this pet.March 11, 2026, 10:19 pm
We'll also keep you updated on Monte's adoption status with email updates.
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Photo of Monte

Monte

Mastiff

Male, Young
Goodyear, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs,
Story
You can fill out an adoption application online on our official website.Meet Monte   Monte and his brother Mojo found themselves in the shelter in the city of San Bernardino after being picked up as strays. Both boys were struggling with pneumonia and also had cherry eye, a surgery many people are hesitant to take on due to the cost. Sadly, that meant their chances of making it out of the shelter were very slim.   Thankfully Monte got his second chance. He is now healthy, feeling great, and ready for his cherry eye surgery and—most importantly—ready to find his forever home.   Monte is a sweet boy who loves going for walks and enjoys a good cuddle with his people. He does best in playgroups with one or two other dogs, preferably females. Monte is a little under-socialized and would thrive in a home that will continue helping him experience the world—more walks, outings, and positive social time.   He’s truly a diamond in the rough and with the right guidance will blossom into an incredible companion. Monte is about 1½–2 years old and is looking for a home experienced with large, powerful breeds that understands the needs of dogs like him.   Put in your application and come meet Monte today — your new best friend may be waiting.   Website: www.azmastiffrescue.com   #azmastiffrescue #mastiffrescue #canecorso #corsolove #adoptmastiff #mastifflove #rescuedog #rescueismyfavoritebreed #adoptdontshop #giantbreedlove #corsonation #dogrescue #foreverhomewanted #mastiffsofinstagram #adoptabledogs  Visit this organization's web site to see any additional information available about this pet.March 11, 2026, 9:57 pm
We'll also keep you updated on Miles puppy's adoption status with email updates.
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Miles puppy

Mastiff

Male, Puppy
Goodyear, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
You can fill out an adoption application online on our official website.Meet Miles! Miles is a 17-week-old Mastiff mix with the perfect combination of puppy curiosity and gentle giant energy. Even at a young age, he’s already showing the loyal, affectionate personality Mastiffs are known for. This sweet boy loves being around people and is happiest when he’s close to his humans, whether that’s playing with toys, exploring the yard, or curling up for a nap after a busy puppy day. Miles is still learning about the world and will thrive with a family committed to continuing his training, socialization, and puppy basics. Like most Mastiff mixes, Miles will likely grow into a large, loyal companion, so he’ll do best with adopters who are prepared for a big dog and the love (and drool!) that comes with it. At just 17 weeks old, Miles has his whole life ahead of him and is ready to find a family that will help him grow into the amazing dog he’s meant to be. If you’re looking for a loyal best friend to grow up with your family, Miles might just be your perfect match. &#226&#157&#164&#239&#184&#143 AZ Mastiff Rescue Phoenix, Arizona Fill out an application at: www.azmastiffrescue.com Our adoption coordinator will be in touch ASAP #azmastiffrescue #pacc911partner #rescuedismyfavoritebreed #adoptdontshop #mastiff #englishmastiff #canecorso #giantbreed #dougedebordeaux #droolhappens #phoenixarizonaVisit this organization's web site to see any additional information available about this pet.March 11, 2026, 2:44 am
We'll also keep you updated on Rob Thomas's adoption status with email updates.
Photo of Rob Thomas

Rob Thomas

Mastiff

Male, Puppy
Goodyear, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained,
Story
You can fill out an adoption application online on our official website.Meet Rob Thomas — a sweet, big lug of a dog who is basically a furry giant marshmallow. At about 1 yr old, Rob is house-trained and crate-trained and has wonderful manners in the home.   Rob previously lived in a foster home with several other dogs and truly enjoys canine companionship, so his ideal home would include one or two other dogs to keep him company. Like many giant breeds, he thrives with structure, space, and people who understand and appreciate these gentle giants.   He’s a lovable, easygoing boy with a big heart, and someone out there is going to get an absolute gem of a dog. Rob would do best in a home with children over the age of five simply due to his size and enthusiasm for life.   If you’re looking for a loyal companion with a marshmallow personality, Rob Thomas might just be your guy.   Arizona Mastiff Rescue #ArizonaMastiffRescue #RescueDog #AdoptDontShop #GiantBreedLove #MastiffRescue #AdoptRobThomas #RescueMastiff  Visit this organization's web site to see any additional information available about this pet.March 11, 2026, 9:24 am
We'll also keep you updated on Joyce's adoption status with email updates.
Photo of Joyce

Joyce

Mastiff

Female, Young
Goodyear, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained,
Story
You can fill out an adoption application online on our official website.  Joyce waited for someone who never came…   Joyce is a 2-year-old Mastiff who found herself scared and confused in the Lancaster shelter. When we first reached out to pull her, we were told she already had an adopter waiting. We were relieved… we thought her story was about to have a happy ending.   But the adopter never came back.   After Joyce was spayed, she sat and waited. And waited. Days passed. No one returned for her. A week later we saw her name appear on the E-List. By then she was sick, depressed, and completely shut down.   We dropped everything and rushed to the shelter. Twenty minutes later Joyce was walking out the door with us.   Now that she’s safe, the real Joyce is starting to show. Beneath the fear is a very sweet, gentle, submissive girl who just wants to feel safe again. She is dog friendly, appears to be house trained, and has been very respectful in the home.   Right now Joyce is learning that people won’t leave her behind again. She’s slowly gaining confidence every day.   What she needs most now is a patient, loving home that will give her the time and reassurance she deserves.   Because the first person who promised her a home didn’t show up…   But the right one still can.   Az Mastiff Rescue   #azmastiffrescue #mastiffrescue #mastifflove #rescuedog #secondchance #adoptdontshop #shelterdog #bigdoglove #mastiffsofinstagram #dogrescue #rescueismyfavoritebreed   Visit this organization's web site to see any additional information available about this pet.March 11, 2026, 1:59 am

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Arizona.

Mastiff puppies and dogs in Arizona cities

Mastiff shelters & rescues in Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Shelter

Pima Animal Care Center

4000 N. Silverbell Road, Tucson , AZ 85745

Pet Types: cats, dogs, rabbits, small animals

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Shelter

Paws Without Borders

4115 East Lester Street, Tucson , AZ 85712

Pet Types: dogs

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Rescue

The Big Mutt Network Inc

10875 S GREAT HORNED OWL WAY, Vail , AZ 85641

Pet Types: dogs

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Shelter

Pinal County Animal Care and Control

1150 S. Eleven Mile Corner Rd, Casa Grande , AZ 85194

Pet Types: cats, dogs

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Rescue

Underdog Rescue of Arizona

P.O. Box 13392, Chandler , AZ 85248

Pet Types: cats, dogs

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Rescue

Valley Dogs

P.O. Box 364, Gilbert , AZ 85299

Pet Types: dogs

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Shelter

Arizona Animal Welfare League

25 N. 40th Street, Phoenix , AZ 85034

Pet Types: cats, dogs

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Shelter

Arizona Humane Society - South Mountain Campus

1521 W Dobbins Road, Phoenix , AZ 85041

Pet Types: cats, dogs, rabbits, small animals

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Shelter

Arizona Humane Society - Papago Park Campus

5501 E. Van Buren Ave, Phoenix , AZ 85008

Pet Types: cats, dogs, rabbits, small animals

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Rescue

FREEDOM BROTHERS RESCUE

Phoenix , AZ 85028

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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