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Mastiff puppies and dogs in Arizona

Looking for a Mastiff puppy or dog in Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Arizona

Below are our newest added Mastiffs available for adoption in Arizona. To see more adoptable Mastiffs in Arizona, use the search tool below to enter specific criteria!
We'll also keep you updated on Annie - ADOPTED's adoption status with email updates.
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Photo of Annie - ADOPTED

Annie - ADOPTED

Mastiff

Female, Young
Goodyear, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs,
Story
You can fill out an adoption application online on our official website.Annie is Adopted!!Visit this organization's web site to see any additional information available about this pet.March 24, 2026, 11:27 am
We'll also keep you updated on Caine's adoption status with email updates.
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Caine

Mastiff/German Shepherd Dog

Male, Adult
Lake Havasu City, AZ
Size
(when grown) -
Details
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Story
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We'll also keep you updated on HUBBA BUBBA's adoption status with email updates.
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HUBBA BUBBA

Mastiff

Male, 1 yr
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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We'll also keep you updated on KATO's adoption status with email updates.
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KATO

Mastiff/Pit Bull Terrier

Male, 1 yr 6 mos
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Available for Adoption! (Courtesy Post — NOT a GTDR dog) Meet Kato, your New Best Friend! Looking for a loyal companion who’s full of love and gentle energy. A sweet soul with a heart of gold! Kato is one of the kindest dogs you’ll ever meet. He rarely barks, has a calm and gentle spirit, and absolutely adores cuddles. Whether you're lounging on the couch or out for a playful walk, Kato just wants to be by your side. He’s great with kids and other dogs, making him the perfect addition to a loving family. Kato is playful, affectionate, and always ready for a good time – but he also knows how to just chill and enjoy the moment. Kato is searching for a forever home where he can be someone’s best friend – a place where he can feel safe, loved, and truly part of the family. If you're looking for a four-legged friend to fill your days with love and joy, Kato is your guy. Let’s find him the home he deserves! Interested in adopting Kato or learning more? Reach out today – his forever family might just be you. Kato is crate trained, potty trained and leash trained, he is neutered, microchipped (chip courtesy of GTDR), Vaccinations UTD. Kato will go home with some transitional food, harness, collar and leash. Private message if interested! ##2221437##
We'll also keep you updated on DEBRA's adoption status with email updates.
Photo of DEBRA

DEBRA

Mastiff/Husky

Female, 1 yr 1 mo
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Why I`d make a great companion: ~Wooof! My name is Debra and I weigh 49 LBS! ~I have a giant body and a soft, gentle heart! ~I grew up in a home with lots of other dogs, so I didn’t get much one-on-one attention or chances to experience everyday things yet, but I`m eager to learn and spend time in the outside world so please be patient with me! ~Underneath this build, is a sensitive, very sweet lady ready to show her loving side! ~Come down and say hello to me today! Type of home I`m looking for: ~A patient and kind home that understands to go slow with me and help me build my confidence! ~All children in my furture home need to be 10+ years old! ~My adoption fee is: $99
We'll also keep you updated on Mojo's adoption status with email updates.
Photo of Mojo

Mojo

Mastiff

Male, Young
Goodyear, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs,
Story
You can fill out an adoption application online on our official website.Meet Mojo   Mojo came into rescue with his brother Monte after both boys found themselves in a shelter in San Bernardino. Sadly, they both came down with pneumonia and were placed on the E-list. Thankfully they made it out in time and are now safe with us.   Now that Mojo is healthy, he’s ready for the next step — his cherry eye surgery and neuter — and then he’ll be ready to find his forever home.   Mojo is the more outgoing of the two brothers. He loves going for walks, enjoys toys, and is always happy to cuddle up with his people. He’s dog friendly and does best with female dogs. Mojo has a fun, loving personality and is the kind of dog who will happily join you on adventures and then curl up for snuggles afterward.   If you’re looking for a loyal companion with a playful side and a big heart, Mojo might be your guy.   Put in your application and come meet Mojo — you might just meet your next best friend.   Az Mastiff Rescue www.azmastiffrescue.com   #azmastiffrescue #adoptdontshop #mastiffrescue #rescuedog #mastifflove #bigdogsofinstagram #adoptmastiff #rescuedismyfavoritebreed #dogrescue #foreverhomewanted #mastiffmix #doglover #rescueismyfavoritebreed  Visit this organization's web site to see any additional information available about this pet.March 11, 2026, 10:19 pm

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Arizona.

Mastiff puppies and dogs in Arizona cities

Mastiff shelters & rescues in Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

The Big Mutt Network Inc

10875 S GREAT HORNED OWL WAY, Vail , AZ 85641

Pet Types: dogs

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Shelter

Pima Animal Care Center

4000 N. Silverbell Road, Tucson , AZ 85745

Pet Types: cats, dogs, rabbits, small animals

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Shelter

Paws Without Borders

4115 East Lester Street, Tucson , AZ 85712

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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