Mastiff Adoption in Mesa, AZ: Mastiff Puppies for Sale in Mesa, AZ

Adopt a Mastiff near you in Mesa, Arizona

These Mastiffs are available in Mesa, Arizona.

MARABELLE

Mastiff

Female, 6 yrs

Mesa, AZ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

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KATO

Mastiff Pit Bull Terrier

Male, 1 yr 7 mos

Mesa, AZ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Available for Adoption! (Courtesy Post — NOT a GTDR dog) Meet Kato, your New Best Friend! Looking for a loyal companion who’s full of love and gentle energy. A sweet soul with a heart of gold! Kato is one of the kindest dogs you’ll ever meet. He rarely barks, has a calm and gentle spirit, and absolutely adores cuddles. Whether you're lounging on the couch or out for a playful walk, Kato just wants to be by your side. He’s great with kids and other dogs, making him the perfect addition to a loving family. Kato is playful, affectionate, and always ready for a good time – but he also knows how to just chill and enjoy the moment. Kato is searching for a forever home where he can be someone’s best friend – a place where he can feel safe, loved, and truly part of the family. If you're looking for a four-legged friend to fill your days with love and joy, Kato is your guy. Let’s find him the home he deserves! Interested in adopting Kato or learning more? Reach out today – his forever family might just be you. Kato is crate trained, potty trained and leash trained, he is neutered, microchipped (chip courtesy of GTDR), Vaccinations UTD. Kato will go home with some transitional food, harness, collar and leash. Private message if interested! ##2221437##

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Or, how about these Mastiffs in cities near Mesa, Arizona

These Mastiffs are available for adoption close to Mesa, Arizona.

MARABELLE

Mastiff

Female, 6 yrs

Mesa, AZ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

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KATO

Mastiff Pit Bull Terrier

Male, 1 yr 7 mos

Mesa, AZ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

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Chewy

Mastiff

Male, 5 yrs 11 mos

Phoenix, AZ

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Story

Hey there I`m Chewy!- I`m a such a dapper older gentleman looking for a place to retire!- Just a big boy with an even bigger heart!- I have lived in a home before so I know how to be an amazing roommate!- I`m a really smart boy and know lots of tricks like sit, shake, and speak!!- I need to be the only animal in the home, but don`t worry, I have so much love to give, I`m the only one you`ll ever need!- I can be a little timid and may do best with children aged middle school and up. - Energy level: Now and Then. I can enjoy a good walk a day with my future family, but I also love playing some tug, and NAPS!*My adoption fee is sponsored by Peerless Plumbing. This means you can take me home for FREE!*I am currently in a foster home. Please contact HWB@aawl.org to schedule a time to meet me!25 N. 40th StPhoenix AZ 85034602-273-6852Adoption Hours:Monday - ClosedTuesday - Friday & Sunday - 11:30am - 6:00pmSaturday - 10:30am - 6:00pm.AAWL requires that all adopted dogs leave with a leash and collar and all cats leave in a carrier.

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Leah

Mastiff Labrador Retriever

Female, Young

Phoenix, AZ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Leah is a stunning 90 lb Mastador (75% English Mastiff / 25% Lab) who perfectly captures the best of both worlds. At her core, she is a world-class lounger. If there is a TV on and a spot on the rug, Leah is happy to be your companion for a movie marathon. But don't let the Mastiff side fool you—the Labrador in her comes out the second she sees a pool! Leah is a rare big girl who loves to swim and play in the water. She is wonderful with children and other dogs, making her a great fit for a busy home. Leah does have a sensitive soul. She thrives on companionship and can get anxious and a bit 'mischievous' if left alone . She’s looking for a family where someone is home more often than not. Because she values her meals highly (food aggressive), she needs a home that understands how to give her a quiet, safe space to eat away from other pets. If you’re looking for a giant sweetheart who will watch your favorite shows with you and join you for a summer swim, Leah is your girl

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Ponzi

Mastiff Labrador Retriever

Male, 2 mos

Phoenix, AZ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, Spayed or Neutered, Shots are up-to-date,

Story

Hi, My name is Ponzi! I was brought to ATR on 2/26/26 with my mom and siblings. Now, we have a safe and loving place to stay until we find our furever home! You can schedule an appointment to meet me on 4/3 I can’t wait to meet you! To meet this pup, schedule an appointment by going to www.adoptapup.as.me and selecting Meet Our Pups! or Meet our Adult Dogs!

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Perjury

Mastiff Labrador Retriever

Female, 2 mos

Phoenix, AZ

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs, Spayed or Neutered, Shots are up-to-date,

Story

Hi, My name is Perjury! I was brought to ATR on 2/26/26 with my mom and siblings. Now, we have a safe and loving place to stay until we find our furever home! You can schedule an appointment to meet me on 4/3 I can’t wait to meet you! To meet this pup, schedule an appointment by going to www.adoptapup.as.me and selecting Meet Our Pups! or Meet our Adult Dogs!

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These pups are in Mesa, Arizona too!

Below are our newest added Mastiffs available for adoption in Mesa, Arizona. To see more adoptable Mastiffs in Mesa, Arizona, use the search tool below to enter specific criteria!

Pancho

St. Bernard

Male, 1 yr

Mesa, AZ

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs, Spayed or Neutered, Shots are up-to-date,

Story

Pancho is a gentle giant with a heart just as big as his paws ❤️ This 119-pound Saint Bernard is equal parts cuddle buddy, loyal companion, and laid-back best friend. Despite his impressive size, Pancho is a total softie who just wants to be close to his people—preferably leaning on you like the oversized teddy bear he is.He’s got that classic Saint Bernard charm: soulful eyes, a sweet disposition, and a calm, easygoing nature that makes everyone fall in love instantly. Whether he’s lounging by your side, going for a slow stroll, or soaking up attention, Pancho is happiest just being part of the family.Pancho was neutered and had a gastropexy performed on 04/09/26, giving him a great head start on a healthy future 💙If you’ve got room in your heart (and on your couch) for a big, lovable boy, Pancho is ready to fill your home with warmth, drool, and unconditional love 🐶💛

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Pancha

St. Bernard

Female, 1 yr

Mesa, AZ

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with dogs, Spayed or Neutered, Shots are up-to-date,

Story

Meet Pancha 🤎🐾 — your future oversized cuddle companion!This beautiful Saint Bernard girl is as sweet as she is stunning. At 106 pounds of pure love, Pancha is basically a living, breathing teddy bear who just wants a cozy spot by your side and a family to adore her.Pancha was recently spayed and had a gastropexy (04/09/26), so she’s all set for a healthy future and ready to focus on the important things in life—like belly rubs, snack time, and perfecting her snuggle skills.With her gentle nature and soulful eyes, Pancha has that classic Saint Bernard charm: calm, affectionate, and incredibly loyal. She’s the kind of dog who will happily lean into you for hugs (and yes… you will feel all 106 pounds of love 💕).If you’ve been dreaming of a big-hearted best friend who will fill your home (and your couch) with warmth, Pancha is your girl.Come meet this gentle giant and fall in love 💫

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Mesa, Arizona.

Mastiff puppies and dogs in Mesa, Arizona

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Adopt a Mastiff near you in Mesa, Arizona

These Mastiffs are available in Mesa, Arizona.

Or, how about these Mastiffs in cities near Mesa, Arizona

These Mastiffs are available for adoption close to Mesa, Arizona.

These pups are in Mesa, Arizona too!

Below are our newest added Mastiffs available for adoption in Mesa, Arizona. To see more adoptable Mastiffs in Mesa, Arizona, use the search tool below to enter specific criteria!

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Mesa, Arizona

Mastiff shelters & rescues in Mesa, Arizona

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Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics

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Mastiff puppies and dogs in Mesa, Arizona

Learn More:

Adopt a Mastiff near you in Mesa, Arizona

These Mastiffs are available in Mesa, Arizona.

Or, how about these Mastiffs in cities near Mesa, Arizona

These Mastiffs are available for adoption close to Mesa, Arizona.

These pups are in Mesa, Arizona too!

Below are our newest added Mastiffs available for adoption in Mesa, Arizona. To see more adoptable Mastiffs in Mesa, Arizona, use the search tool below to enter specific criteria!

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Mesa, Arizona

Mastiff shelters & rescues in Mesa, Arizona

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics