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Mastiff puppies and dogs in Mesa, Arizona

Looking for a Mastiff puppy or dog in Mesa, Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you Mastiff in cities near Mesa, Arizona Other pups in Mesa, Arizona Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Mesa, Arizona Mastiff shelters and rescues in Mesa, Arizona Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Mesa, Arizona

These Mastiffs are available in Mesa, Arizona.
We'll also keep you updated on Barkley's adoption status with email updates.
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Barkley

Mastiff Shar Pei

Male, Adult
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered,
Story
Barkley is a great dog. He's a protector, sweet and loyal. He's beautiful. We rescued him 4 years ago, after our previous dog passed away after 13 years. We love him and will keep until a good home is found but he's not a good fit for our family. He needs social attention. He has anxiety and separation issues. He will follow u every where. No aggression. Never bitten anyone. He is great around our kids but when they start playing or get excited he gets to excited with them. Jumping and bumping into them. He's kncoked them down and into objects. This is our main reason for wanting to rehome him. Not good with small children for that reason. He's good with small dogs, as we have another small dog but he is not good with other large dogs. We want to make sure he goes to a very good and loving home where he fits well.

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Or, how about these Mastiffs in cities near Mesa, Arizona

These Mastiffs are available for adoption close to Mesa, Arizona.
We'll also keep you updated on Barkley's adoption status with email updates.
Photo of Barkley

Barkley

Mastiff Shar Pei

Male, Adult
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered,
Story
Barkley is a great dog. He's a protector, sweet and loyal. He's beautiful. We rescued him 4 years ago, after our previous dog passed away after 13 years. We love him and will keep until a good home is found but he's not a good fit for our family. He needs social attention. He has anxiety and separation issues. He will follow u every where. No aggression. Never bitten anyone. He is great around our kids but when they start playing or get excited he gets to excited with them. Jumping and bumping into them. He's kncoked them down and into objects. This is our main reason for wanting to rehome him. Not good with small children for that reason. He's good with small dogs, as we have another small dog but he is not good with other large dogs. We want to make sure he goes to a very good and loving home where he fits well.

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We'll also keep you updated on Hope's adoption status with email updates.
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Hope

Mastiff Cane Corso

Female, 3 yrs 8 mos
Gilbert, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Hope! Hope’s name says it all—she’s the definition of resilience and new beginnings. Likely a Mastiff/Cane Corso mix, she currently weighs about 60 pounds (and still filling out beautifully). When rescued, Hope was heartbreakingly underweight at just 56 pounds, likely abandoned by a breeder and left to survive on her own. But through it all, her gentle, loving spirit never wavered. Now healthy, happy, and about 3–4 years old, Hope is blossoming into the incredible dog she was always meant to be. She’s a perfect mix of cuddle companion and adventure buddy—content to curl up next to you for a movie night or join you on a walk or hike. She’s playful, affectionate, and has that soulful look that melts your heart. Hope walks beautifully on a leash, adores people, and just wants to be close to her humans. She’s ready for a home where she can continue to thrive, surrounded by love, comfort, and a family who sees how special she truly is. * Fully vetted * Sweet, affectionate, and fun-loving * Loves walks, hikes, and being by your side * Ready to give (and receive!) all the love If you think Hope might be your perfect match, please email adopt@valleydogs.org for more information.

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We'll also keep you updated on SABIRA's adoption status with email updates.
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SABIRA

Mastiff

Female, 8 mos
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Why I`d make a great companion: ~Boof! My name is Sabira and I weigh 72 LBS! ~I got my name because I always bring smiles to everyone`s faces! I`m just a sweet pup who loves affection, attention, and a nice, sniffy, moseying walk! ~Don`t be fooled, I may be big already but I`m only gonna get bigger! ~Come and visit with me today, I`m excited to meet you!Type of home I`m looking for: ~I need to meet all dogs who will be living in my new home. ~A home that can match this giants energy! ~My adoption fee is: SPONSORED BY HILL`S PET NUTRITION!

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We'll also keep you updated on BROWNIE's adoption status with email updates.
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BROWNIE

Mastiff

Female, 5 yrs
Phoenix, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
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We'll also keep you updated on Chewy's adoption status with email updates.
Photo of Chewy

Chewy

Mastiff

Male, 5 yrs 8 mos
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Hey there I`m Chewy!- I`m a distinguished handsome older gentleman searching for a place I can finally call home.- Sweetest big boy you’ll ever meet — a huge lover with a heart full of loyalty for my humans.- When I love, I love hard, and I’ll happily be right by your side, leaning on you and keeping you company.- Laid-back guy, also known as a couch potato- I’d prefer to be the only dog in the home- If I sound like your perfect guy come meet me and we`ll be a perfect match!*My adoption fee is sponsored by Peerless Plumbing. This means you can take me home for FREE!*No appointment necessary!25 N. 40th StPhoenix AZ 85034602-273-6852Adoption Hours:Monday - ClosedTuesday - Friday & Sunday - 11:30am - 6:00pmSaturday - 10:30am - 6:00pm.AAWL requires that all adopted dogs leave with a leash and collar and all cats leave in a carrier.

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We'll also keep you updated on Moose's adoption status with email updates.
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Moose

Mastiff Great Dane

Male, Young
Phoenix, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
I rescued this sweet boy May 1st 2025 from a neglected home. At this time I had a large house with a backyard, unfortunately now I have moved out and have been traveling the country with him since early October and he has not handled life on the road very well. He needs proper kennel training and also a yard to run around in. He’s not the type for hotel rooms or small Airbnbs. He’s the best dog at dog parks, plays kindly with kids, and has never show any aggression to other animals. He is an extreme cuddle buddy and gentle giant, but it’s the time away where he struggles. He has broken out of every kennel I’ve purchased and can open nearly every door except round doorknobs. Ideal situation for him is something with a yard and even another dog to play with. I am planning on moving to Idaho once I get my condo listed for sale (will be listed on January 7th). It’s not fair for him to relocate to a smaller place where I am gone working for up to 8 hours at a time with no supervision.

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Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Mesa, Arizona.

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Mastiff puppies and dogs in nearby cities

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Related breeds in Mesa, Arizona

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Mastiff shelters & rescues in Mesa, Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Mesa, Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

8.1 miles

Valley Dogs

P.O. Box 364, Gilbert, AZ 85299

Pet Types: dogs

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Shelter

9.5 miles

Arizona Humane Society - Papago Park Campus

5501 E. Van Buren Ave, Phoenix, AZ 85008

Pet Types: cats, dogs, rabbits, small animals

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Shelter

10.7 miles

Arizona Animal Welfare League

25 N. 40th Street, Phoenix, AZ 85034

Pet Types: cats, dogs

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Rescue

11.9 miles

Love Them All Sanctuary + Rescue

Scottsdale, AZ 85259

Pet Types: dogs

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Rescue

14.1 miles

FREEDOM BROTHERS RESCUE

Phoenix, AZ 85028

Pet Types: dogs

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Shelter

16.2 miles

HALO Animal Rescue

3227 E. Bell Rd., Ste D151, Phoenix, AZ 85032

Pet Types: cats, dogs

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Shelter

16.4 miles

Maricopa County Animal Care & Control West Animal Shelter

2500 S. 27th Avenue, Phoenix, AZ 85009

Pet Types: dogs

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Rescue

24.4 miles

Regal Dane Rescue

4410 W UNION HILLS DR STE 7-187, GLENDALE, AZ 85308

Pet Types: dogs

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Rescue

26.7 miles

Handover Rover

Scottsdale, AZ 85262

Pet Types: cats, dogs

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Rescue

31.4 miles

AZ Mastiff Rescue- English Mastiff and Other Mastiff and Giant breeds

Goodyear, AZ 85338

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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