Adopt
Rehome
Menu Hamburger Icon

Mastiff puppies and dogs in Mesa, Arizona

Looking for a Mastiff puppy or dog in Mesa, Arizona? Adopt a Pet can help you find an adorable Mastiff near you.

Picture of Mastiff

Learn More:

Adopt a Mastiff near you Mastiff in cities near Mesa, Arizona Other pups in Mesa, Arizona Search for a Mastiff puppy or dog near you Browse Mastiff puppies and dogs in nearby cities Browse related breeds in Mesa, Arizona Mastiff shelters and rescues in Mesa, Arizona Learn more about adopting a Mastiff puppy or dog

Adopt a Mastiff near you in Mesa, Arizona

These Mastiffs are available in Mesa, Arizona.
Photo of MARABELLE

MARABELLE

Mastiff

Female, 3 yrs 8 mos
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-

Learn More

Small right facing arrow
Photo of LU LU

LU LU

Mastiff

Female, 4 yrs 3 mos
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-

Learn More

Small right facing arrow
Photo of Fern

Fern

English Mastiff Irish Wolfhound

Female, Adult
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Fern is a five-year-old Irish Wolfhound, Great Dane, and Mastiff mix with the sweetest sugary face and a personality to match. This one-of-a-kind girl is the kind of dog who makes everyone she meets smile, effortlessly winning hearts with her gentle nature and loving spirit. Now in the care of Big Hearts for Big Breeds, Fern has shown herself to be an absolute treasure. She is wonderful with other dogs, great with cats, and loves kids, making her the kind of companion who fits beautifully into a variety of family dynamics. Whether she's making new friends or simply enjoying quiet time with her people, Fern brings warmth and joy wherever she goes. With her unique blend of giant breeds comes an equally giant heart. She’s affectionate without being demanding, sweet without trying, and has the kind of calm presence that makes every day a little brighter. Her soulful eyes and sugar-dusted face tell the story of a dog who is simply happy to be loved and to love in return. If you've been searching for a loyal best friend who gets along with everyone and has enough love to fill an entire home, Fern may be exactly the companion you've been waiting for. Big Hearts for Big Breeds can't wait to see this special girl find the forever family she so richly deserves.

Learn More

Small right facing arrow
Photo of Janice

Janice

English Mastiff

Female, Young
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Janice is a female Mastiff mix pup who recently joined the Big Hearts for Big Breeds crew. She's got the kind of sweet face that instantly melts hearts! Janice is another sibling from the beloved “Friends” foster pups, and she’s already showing what a special girl she is. Playful and curious, Janice is settling right into her new foster home and learning the ropes alongside other large dogs. She enjoys playtime, companionship, and is gaining confidence every day as she adapts to her new surroundings. With her loving nature and easygoing personality, Janice is ready to grow into a wonderful companion for a family who will continue guiding her, loving her, and cheering her on as she blossoms.

Learn More

Small right facing arrow
Photo of Maple

Maple

English Mastiff

Female, Young
Mesa, AZ
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Maple is a one-year-old Mastiff mix who may be petite in size, but she’s overflowing with personality, playfulness, and charm. Now in the care of Big Hearts for Big Breeds, this sweet young girl is ready to find a forever family to grow up with. Maple is the sibling of some familiar Big Hearts faces—the beloved “Friends” crew, Rachel, Monica, Phoebe, and Janice—but she’s just beginning her own rescue journey. Like her siblings, she is shy and timid at first, but she truly has a loving heart and is eager to make lasting connections with the people around her. Still very much a puppy, Maple loves to play and brings a fun, energetic spirit wherever she goes. She does well with other dogs and was around cats when she was younger, giving her a solid foundation as she continues to learn and mature. With continued guidance, socialization, and plenty of positive experiences, she’s sure to blossom into an incredible companion. Maple is looking for a family that will embrace her youthful enthusiasm, celebrate her milestones, and give her all the love she deserves. If you’re searching for a playful, affectionate best friend with a bright future ahead, Maple might just be the perfect addition to your home.

Learn More

Small right facing arrow

Or, how about these Mastiffs in cities near Mesa, Arizona

These Mastiffs are available for adoption close to Mesa, Arizona.
Photo of MARABELLE

MARABELLE

Mastiff

Female, 3 yrs 8 mos
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-

Learn More

Small right facing arrow
Photo of LU LU

LU LU

Mastiff

Female, 4 yrs 3 mos
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
-

Learn More

Small right facing arrow
Photo of Fern

Fern

English Mastiff Irish Wolfhound

Female, Adult
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
Fern is a five-year-old Irish Wolfhound, Great Dane, and Mastiff mix with the sweetest sugary face and a personality to match. This one-of-a-kind girl is the kind of dog who makes everyone she meets smile, effortlessly winning hearts with her gentle nature and loving spirit. Now in the care of Big Hearts for Big Breeds, Fern has shown herself to be an absolute treasure. She is wonderful with other dogs, great with cats, and loves kids, making her the kind of companion who fits beautifully into a variety of family dynamics. Whether she's making new friends or simply enjoying quiet time with her people, Fern brings warmth and joy wherever she goes. With her unique blend of giant breeds comes an equally giant heart. She’s affectionate without being demanding, sweet without trying, and has the kind of calm presence that makes every day a little brighter. Her soulful eyes and sugar-dusted face tell the story of a dog who is simply happy to be loved and to love in return. If you've been searching for a loyal best friend who gets along with everyone and has enough love to fill an entire home, Fern may be exactly the companion you've been waiting for. Big Hearts for Big Breeds can't wait to see this special girl find the forever family she so richly deserves.

Learn More

Small right facing arrow
Photo of Janice

Janice

English Mastiff

Female, Young
Mesa, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Janice is a female Mastiff mix pup who recently joined the Big Hearts for Big Breeds crew. She's got the kind of sweet face that instantly melts hearts! Janice is another sibling from the beloved “Friends” foster pups, and she’s already showing what a special girl she is. Playful and curious, Janice is settling right into her new foster home and learning the ropes alongside other large dogs. She enjoys playtime, companionship, and is gaining confidence every day as she adapts to her new surroundings. With her loving nature and easygoing personality, Janice is ready to grow into a wonderful companion for a family who will continue guiding her, loving her, and cheering her on as she blossoms.

Learn More

Small right facing arrow
Photo of Maple

Maple

English Mastiff

Female, Young
Mesa, AZ
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Maple is a one-year-old Mastiff mix who may be petite in size, but she’s overflowing with personality, playfulness, and charm. Now in the care of Big Hearts for Big Breeds, this sweet young girl is ready to find a forever family to grow up with. Maple is the sibling of some familiar Big Hearts faces—the beloved “Friends” crew, Rachel, Monica, Phoebe, and Janice—but she’s just beginning her own rescue journey. Like her siblings, she is shy and timid at first, but she truly has a loving heart and is eager to make lasting connections with the people around her. Still very much a puppy, Maple loves to play and brings a fun, energetic spirit wherever she goes. She does well with other dogs and was around cats when she was younger, giving her a solid foundation as she continues to learn and mature. With continued guidance, socialization, and plenty of positive experiences, she’s sure to blossom into an incredible companion. Maple is looking for a family that will embrace her youthful enthusiasm, celebrate her milestones, and give her all the love she deserves. If you’re searching for a playful, affectionate best friend with a bright future ahead, Maple might just be the perfect addition to your home.

Learn More

Small right facing arrow
Photo of Bruno

Bruno

Mastiff

Male, 2 yrs 2 mos
Gilbert, AZ
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Meet Bruno 🐾 Bruno is a handsome ~2-year-old brindle boy with a gentle soul and a heart that just needs a little time to shine. At first, he can be a bit shy and timid, but once he warms up, you’ll see his sweet and loyal personality come through. He does well with most other dogs and would likely enjoy a home with a calm, friendly companion to help build his confidence. Bruno would thrive in a patient, loving home where he can take things at his own pace and feel safe. He’s the kind of dog that forms a deep bond with his people—quiet, observant, and incredibly loving once he trusts you. With a little reassurance and consistency, Bruno is going to blossom into an amazing companion. If you’re looking for a loyal best friend and are willing to give him the time he deserves, Bruno might just be your perfect match ❤️ Please email ADOPT@VALLEYDOGS.ORG for an adoption application. Thank you!

Learn More

Small right facing arrow

These pups are in Mesa, Arizona too!

Below are our newest added Mastiffs available for adoption in Mesa, Arizona. To see more adoptable Mastiffs in Mesa, Arizona, use the search tool below to enter specific criteria!
Photo of Mud

Mud

St. Bernard

Male, Adult
Mesa, AZ
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Good with cats, House-trained, Spayed or Neutered,
Story
Mud is a two-year-old Saint Bernard with a heart as big as his paws and a personality that wins over everyone he meets. This handsome boy is the definition of a gentle giant, bringing smiles wherever he goes with his playful spirit, sweet nature, and unmistakable Saint Bernard charm. Now in the care of Big Hearts for Big Breeds, Mud has proven to be an exceptional companion. He is wonderful with kids, loves people, gets along great with other dogs, is good with cats, and has even done well around farm animals. If you're looking for a dog who fits right into family life, Mud checks just about every box. Mud is kennel trained, potty trained, and enjoys spending time with his people, whether that's joining in on adventures or simply relaxing at home. He can get a little enthusiastic on leash and may pull at times, but with continued practice and consistency, he'll continue polishing his walking manners. True to his breed, Mud is affectionate, loyal, and always ready to make a new friend. He's the kind of dog who turns ordinary days into better ones just by being there. If you're looking for a fun-loving, family-friendly Saint Bernard with a heart of gold, Mud is ready to fill your home with laughter, slobbery kisses, and unconditional love. Big Hearts for Big Breeds can't wait to help this incredible boy find the forever family he's been waiting for.

Learn More

Small right facing arrow
Photo of Dirt

Dirt

St. Bernard

Male, Young
Mesa, AZ
Size
(when grown) -
Details
Good with kids, Good with dogs, House-trained, Spayed or Neutered,
Story
Dirt is a 12–18-month-old Saint Bernard who is still growing into both his giant paws and his confidence. Now safe with Big Hearts for Big Breeds, this handsome young boy is looking for a patient family that will help him continue learning that the world is a safe place. Like many young Saint Bernards, Dirt has a gentle heart and a thoughtful nature. He does well with children and has shown himself to be non-reactive around other dogs. His compatibility with cats is currently unknown as we continue to learn more about him. Dirt can be shy and nervous around men when first meeting them, but with patience and kindness, he warms up and begins to show his sweet personality. True to his Saint Bernard roots, he also has a protective nature and appreciates slow, respectful introductions to new people entering the home. Once he understands that everyone is a friend, he settles in nicely. As a young giant-breed dog, Dirt will benefit from continued socialization, structure, and positive experiences that help build his confidence. With the right guidance, he has all the makings of a loyal, loving companion who will be deeply devoted to his family. If you're looking for a young Saint Bernard with a heart of gold and are willing to give him the time he needs to blossom, Dirt may be the perfect addition to your family.

Learn More

Small right facing arrow

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Mesa, Arizona.

    an arrow icon
location arrow icon Current location
  • New York, NY
  • Los Angeles, CA
  • Houston, TX
  • Dallas, TX
  • Brooklyn, NY

Sorry, we can’t find that location! Please try again.

    Age
    an arrow icon

Mastiff puppies and dogs in nearby cities

Mastiff Puppies near me Mastiff in Apache Junction, AZ Mastiff in Avondale, AZ Mastiff in Cave Creek, AZ Mastiff in Chandler, AZ Mastiff in El Mirage, AZ Mastiff in Fountain Hills, AZ Mastiff in Gilbert, AZ Mastiff in Glendale, AZ Mastiff in Goodyear, AZ Mastiff in Guadalupe, AZ Mastiff in Litchfield Park, AZ Mastiff in Maricopa, AZ Mastiff in Paradise Valley, AZ Mastiff in Peoria, AZ Mastiff in Phoenix, AZ Mastiff in Queen Creek, AZ Mastiff in Scottsdale, AZ Mastiff in Surprise, AZ Mastiff in Tempe, AZ Mastiff in Tolleson, AZ

Related breeds in Mesa, Arizona

Bullmastiffs in Mesa, Arizona Neapolitan Mastiffs in Mesa, Arizona Saint Bernards in Mesa, Arizona

Mastiff shelters & rescues in Mesa, Arizona

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Mesa, Arizona. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

2.8 miles

Maricopa County Animal Care & Control East Valley Animal Shelter

1920 S Lewis, Mesa, AZ 85210

Pet Types: dogs

More an arrow icon

Rescue

3.6 miles

Big Hearts for Big Breeds

Mesa, AZ 85202

Pet Types: dogs

More an arrow icon

Rescue

8.1 miles

Valley Dogs

P.O. Box 364, Gilbert, AZ 85299

Pet Types: dogs

More an arrow icon

Shelter

10.7 miles

Arizona Animal Welfare League

25 N. 40th Street, Phoenix, AZ 85034

Pet Types: cats, dogs

More an arrow icon

Rescue

12.8 miles

Underdog Rescue of Arizona

P.O. Box 13392, Chandler, AZ 85248

Pet Types: cats, dogs

More an arrow icon

Rescue

14.1 miles

HARTT

Phoenix, AZ 85028

Pet Types: cats, dogs

More an arrow icon

Rescue

14.5 miles

Desert Dog Project

Scottsdale, AZ 85254

Pet Types: dogs

More an arrow icon

Shelter

16.4 miles

Maricopa County Animal Care & Control West Animal Shelter

2500 S. 27th Avenue, Phoenix, AZ 85009

Pet Types: dogs

More an arrow icon

Rescue

24.4 miles

Regal Dane Rescue

4410 W UNION HILLS DR STE 7-187, GLENDALE, AZ 85308

Pet Types: dogs

More an arrow icon

Rescue

26.7 miles

Handover Rover

Scottsdale, AZ 85262

Pet Types: cats, dogs

More an arrow icon

Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

magnifying glass with cat and dog

Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

clipboard with list

Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

Learn More an arrow icon