Mastiff Adoption in Millbrae, CA: Mastiff Puppies for Sale in Millbrae, CA

Adopt a Mastiff near you in Millbrae, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Millbrae, California

These Mastiffs are available for adoption close to Millbrae, California.

Leo

Mastiff American Pit Bull Terrier

Male, Adult

San Francisco, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Not good with kids, Good with dogs, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Meet Leo 🐾 — A Loyal, Loving CompanionLeo is a loyal, handsome, 5-year-old, 85 lb Mastiff/Pit Bull/Husky/German Shepherd mix with a huge heart for his people. He’s affectionate, intelligent, eager to please, and bonds deeply with those he trusts.Leo loves fetch, sunshine, outdoor adventures, and spending time with other dogs. He does well with dogs of all sizes, including small dogs. He’s house-trained, non-destructive when home alone, and highly trainable.Leo needs an experienced owner and a calm, predictable, adult-only home. He can react out of fear when startled or overwhelmed. He’s muzzle-trained and has worked with the SF SPCA Behavior Program.We love Leo deeply, but our changing family plans and unpredictable city life have led us to seek a better fit for him. We want him to thrive with patient people who give him time to build trust. We’re happy to share more about his history. A rehoming fee may be waived for the right home.

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PENNY

Mastiff

Female, 2 yrs 7 mos

Alameda, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

• Loves affection• Playful, great to walk• Super splasherPenny arrived to us unsure of the world, but has since decided that after careful consideration, the world is actually pretty great!She is gorgeous, gentle, and sweeter than she probably wants you to know. Once she`s comfortable with you, her whole personality opens up: she`s easy to train, takes fetch extremely seriously, and in what may be the best discovery of her to date - she LOVES water. She`s a big fan of splashing around and throwing her tennis balls in. Penny is ready for a patient, loving home that can keep her playtime up and thriving. If you`re looking for a beautiful, big hearted, playful pup - she`s right here!

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Adam

Mastiff Mixed Breed (Medium)

Male, 2 yrs 6 mos

Oakland, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Spayed or Neutered,

Story

Adam is an 80-pound silly, calm and cuddly boy doing so well with his amazing\ foster who says her favorite qualities are his squishy, loveable face, his soft fur, and his smile. Adam walks well on leash and is eager to "sit" for his dinner. He gets along great with other dogs. He is calm, playful and has good manners and is not overly curious about cats. He is low energy but really enjoys going for walks and being let out to run and explore in a fenced area. Adam is protective of his family and property and, with proper introductions, is the most loyal and gentle guy! He needs an adopter who can guide him with boundaries and offer lots of socialization opportunities. Everyone who meets Adam falls in love with him! He's just waiting for the right one who's ready to provide him a stable and loving home. If that's you, please submit an application and a volunteer will be in touch! (HD)

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Romeo

Mastiff

Male, 7 yrs 6 mos

Palo Alto, CA

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Not good with dogs, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

Romeo is very sweet 6 year old boy but the vets think he may be younger. He would love to be a family dog and definitely wants to find his forever home, but can be protective of his people and his space. That being said once he knows you are part of the family he listens very well and knows many commands, sit, stay, down, shake, wait. He is slow to warm up to new people but once he has been introduced to you he is a gentle giant and big couch potato that loves to cuddle. He also really enjoys going for a ride in the car. It is not recommended to have young kids due to his size. He is good on the leash and knows many commands but needs someone that is not afraid of his size and can properly handle him. Experienced adopter with larger breeds is a must. No other dogs or animals in the household and not a good candidate for crates.

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NERO

Mastiff Mixed Breed (Large)

Male, 4 mos

Pt. Richmond, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs,

Story

Meet Nero! He is a pretty sweet easy-going pup who would love a home where he can continue his socialization and training. He would be a great dog for a family with kids and a home where he can get lots of exercise! If you are looking for a fun loving companion, come on down and meet Nero!

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Adonis

Mastiff

Male, Young

Fremont, CA

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

His birthday is December 22, 2025. He is a Mastiff × Doberman × American Staffordshire Terrier mix. He is a wonderful, loving puppy who is great with people and other dogs, but he does need a lot of attention and has some separation anxiety.He had parvo as a puppy but was treated and fully recovered. He is healthy now, but he does need his parvo booster shot one last time We absolutely love him and this is a very difficult decision. Unfortunately, I’m moving and starting college, and I’m no longer able to give him the time, attention, and care he deserves. We just want to find him a loving home where he will be happy, cared for, and given the attention he needs

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Mastiff puppies and dogs in Millbrae, California

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Adopt a Mastiff near you in Millbrae, California

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Millbrae, California

These Mastiffs are available for adoption close to Millbrae, California.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Millbrae, California

Mastiff shelters & rescues in Millbrae, California

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics