Mastiff Adoption in New York: Mastiff Puppies for Sale in New York

Adopt a Mastiff near you in New York

Below are our newest added Mastiffs available for adoption in New York. To see more adoptable Mastiffs in New York, use the search tool below to enter specific criteria!

Diego JuM

Mastiff/Mixed Breed (Large)

Male, 2 yrs

Rochester, NY

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with dogs,

Story

I'm Diego, a striking 2-year-old chocolate and blond brindle Mastiff mix, and I've got the heart of an adventurer! 🐕 At 63 pounds of pure energy and loyalty, I'm already neutered and crate trained—ready to be your partner in crime. I thrive with active owners who can match my enthusiasm, and I'm fantastic with other dogs, so playdates are always a go! If you're looking for a friendly, energetic companion who'll stick by your side through thick and thin, come meet me today. 💪❤️ Local adoption fee is $300 (in TX) Out of state adoption fee is $550 (includes transport to your area)

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Nula

Mastiff/Great Dane

Female, Adult

Marcy, NY

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Not good with cats, House-trained,

Story

Very sweet loyal companion to my mother for the last four years. Unable to continue care for Nula as my mother has recently become quite ill.

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Asha (NY-Sarah)

Mastiff

Female, Puppy

Sherburne, NY

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats,

Story

Interested in this dog? Your new pet is fostered in Smyrna, NY - Contact Sarah (call or text) at 908-745-9191 or you can email her at sarah@eastcoastadoptions.com. You can also fill out an application for this dog at http://eastcoastadoptions.com We are a registered 501(c)3 Non Profit Organization - A Dogs In Danger Rescue, Inc. company. Our dogs and puppies are rescued from shelters and rescues in overpopulated areas of the country and are now available for adoption! All are up to date on vaccines, vet checked, health certified and dewormed. Hours: Please only call between the hours of 8:30am-8:30pm to come see our dogs looking for homes. Appointments are 7 days a week and most holidays as long as someone is available to see you. If you get voicemail, please leave a message and we will get back to you as soon as we can! Many of our locations offer crates, playpens and starter kits (leash, collar, food, toys, treats, bowl etc) for a donation. We do same day adoptions. An application is required before coming to visit our adoptable dogs. We are committed to saving dogs and puppies in need, finding them loving homes, and offering support and education to ensure a successful forever solution for both our dogs and the humans who adopt them. You can find additional information and all of our adoptable dogs listed on our website: http://eastcoastadoptions.com - where you can also fill out an application, find out more about us including our fosters or, simply drop us a line for more information! We look forward to hearing from you and completing your family with another family member! Eastcoastadoptions.com August 24, 2026, 1:03 pm

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Lucy ***Courtesy Listing***

Mastiff

Female, 4 yrs 6 mos

Peru, NY

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, House-trained,

Story

Lucy is a Courtesy Listing Dog, she is not located at Elmore SPCA Shelter, if you are interest on her, please contact her owner directly. Owner info: Penny Wood; Email: wpenny297@gmail.com; Phone# (802) 503-7897Lucy is a gentle giant, she is a sweet girl just needs her forever home. Lucy likes to play with water, runs freely in a big outdoor kennel, she does well riding in cars.

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Marsha

Mastiff

Female, Young

North Collins, NY

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Not good with cats, House-trained,

Story

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Peanut

Mastiff

Female, Young

Rochester, NY

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

House-trained,

Story

👀 Looking for a giant-sized companion who will happily never leave your side? 🤔 🥜 Peanut is a cuddly 3-year-old Boerbel mastiff, around 140lbs, who thinks she’s a lap dog and will be your favorite shadow once you earn her trust. While it appears she didn’t have a lot of socialization in the beginning of her life, she has been learning how to live in a house and has become quite comfortable (though she’s still learning that the TV isn’t scary). She suffers from separation anxiety and can be destructive toward items when left alone. She is nervous about new people and sounds/experiences, so it does take her a little while to warm up. However, she is sweet, empathetic, and will capture your heart with her soulful eyes. 💖Peanut will thrive with an owner experienced with large breeds or someone confident guiding a sometimes fearful, sometimes stubborn 140‑lb girl. She absolutely adores being outside in a secure space — a fenced yard or even a cozy porch would be her happy place, as she loves lounging on the porch at her foster home. Most of all, watching her open up is incredibly rewarding; beneath her anxiety is a big, goofy sweetheart just waiting to blossom with the right person. Peanut is agile for her size and gets her energy out with the zoomies, loves playing with her favorite ball, shaking her rope, or chewing bones. 🎾 She is house trained and crate trained ✅ and will use her open crate as her safe space to hang out (though she’s also quite the escape artist and needs a very secure crate). She knows basic commands (“sit,” “down,” “shake,” working on “stay”) 🎓and walks well on a leash, though she’ll go her own pace and needs some coaxing with treats to keep moving sometimes. 🤭 🏡 Peanut would do best in a family as the only dog, and with patient humans who are committed to helping her continue to overcome her fears. She has a history of playing well with other dogs but has shown resource guarding with food and toys. She is good with kids, but due to her size may be better suited to families with middle-aged/older children. If you can look past the drool 🤤 and are ready for giant paws 🐾 asking for your affection, Peanut will make a wonderful addition to the family. She deserves all the love and will always want to be wherever you are.

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Below are our newest added Mastiffs available for adoption in New York. To see more adoptable Mastiffs in New York, use the search tool below to enter specific criteria!

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Mastiff puppies and dogs in New York

Jump to:

Adopt a Mastiff near you in New York

Below are our newest added Mastiffs available for adoption in New York. To see more adoptable Mastiffs in New York, use the search tool below to enter specific criteria!

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in New York cities

Mastiff shelters & rescues in New York

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog ?

Mastiff information

Mastiff basics