Mastiff Adoption in New York: Mastiff Puppies for Sale in New York

Adopt a Mastiff near you in New York

Below are our newest added Mastiffs available for adoption in New York. To see more adoptable Mastiffs in New York, use the search tool below to enter specific criteria!

Gus (NY-Sarah)

Mastiff

Male, Puppy

Sherburne, NY

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats,

Story

Interested in this dog? Your new pet is fostered in Smyrna, NY - Contact Sarah (call or text) at 908-745-9191 or you can email her at sarah@eastcoastadoptions.com. You can also fill out an application for this dog at http://eastcoastadoptions.com We are a registered 501(c)3 Non Profit Organization - A Dogs In Danger Rescue, Inc. company. Our dogs and puppies are rescued from shelters and rescues in overpopulated areas of the country and are now available for adoption! All are up to date on vaccines, vet checked, health certified and dewormed. Hours: Please only call between the hours of 8:30am-8:30pm to come see our dogs looking for homes. Appointments are 7 days a week and most holidays as long as someone is available to see you. If you get voicemail, please leave a message and we will get back to you as soon as we can! Many of our locations offer crates, playpens and starter kits (leash, collar, food, toys, treats, bowl etc) for a donation. We do same day adoptions. An application is required before coming to visit our adoptable dogs. We are committed to saving dogs and puppies in need, finding them loving homes, and offering support and education to ensure a successful forever solution for both our dogs and the humans who adopt them. You can find additional information and all of our adoptable dogs listed on our website: http://eastcoastadoptions.com - where you can also fill out an application, find out more about us including our fosters or, simply drop us a line for more information! We look forward to hearing from you and completing your family with another family member! Eastcoastadoptions.com June 24, 2026, 12:17 pm

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Grace (NY-Sarah)

Mastiff

Female, Puppy

Sherburne, NY

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats,

Story

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Trojan

Mastiff/Mixed Breed (Large)

Male, 4 yrs 8 mos

Binghamton, NY

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

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Juno

Mastiff

Female, 2 yrs

Amherst, NY

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, House-trained,

Story

Hi there, I’m Juno! My estimated age is 2 years old, yet my foster mom feels I may be younger and still filling out my large paws. I’m currently 70 pounds of wrinkly Mastiff cuteness. I am currently living in a foster home with a female dog and teenage children, and I am doing fantastic with both. I adore humans and other dogs. A home without small children would be ideal for me due to my large size and playful tendencies. I am a gentle dog but still exhibit puppy-like behavior at times. My foster mom is currently working with me on manners, which include crate and potty training. I am learning to accept the crate, despite my preference for being with my humans constantly, and am making great strides in potty training by sticking to a routine. Treats and bones have been excellent incentives, as I’m a very treated motivated girl. As much as I love it here, I’m ready for a forever home of my own. Could that be with you?! If so, apply for me today at www.buffalounderdogs.com ##2763165##

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Hooch

Mastiff/Mixed Breed (Medium)

Male, 2 yrs

Pawling, NY

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Good with cats,

Story

Meet Hooch! This handsome 2-year-old Mastiff mix is 92 pounds of pure love, loyalty, and laid-back charm. While his size may turn heads, it’s his gentle personality that really steals hearts. Hooch is the definition of a good boy—happy to spend his days soaking up attention, enjoying some playtime, and then settling in for a cozy snuggle session with his favorite people. Hooch enjoys leisurely walks where he can take in all the sights and smells at his own pace, and he’s always up for some fun when it’s time to play. Afterward, you’ll usually find him stretched out nearby, content just being part of the family. If you’re looking for a calm, affectionate companion with a giant heart, Hooch may be your perfect match. Ready to give this gentle giant the happy life he deserves? Head over to happylifeanimalrescue.org and register for adoption today! Once you’re registered, you can visit during our open adoption hours or meet Hooch at one of our upcoming adoption events. Big dogs have a special way of filling a home with love, and Hooch is ready to do exactly that!

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Ursula

Mastiff

Female, Young

West Seneca, NY

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Not good with cats, Needs experienced adopter, House-trained,

Story

Ursula is a 2 year old South African Boerbel. She is a very sweet and loving girl. She will do best in a household with men and older children. As well as someone having time to play and exercise with her. She is very energetic. She does not get along with cats or other female dogs.

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Mastiff puppies and dogs in New York

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Below are our newest added Mastiffs available for adoption in New York. To see more adoptable Mastiffs in New York, use the search tool below to enter specific criteria!

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Mastiff shelters & rescues in New York

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Mastiff puppies and dogs in New York

Jump to:

Adopt a Mastiff near you in New York

Below are our newest added Mastiffs available for adoption in New York. To see more adoptable Mastiffs in New York, use the search tool below to enter specific criteria!

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in New York cities

Mastiff shelters & rescues in New York

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog ?

Mastiff information

Mastiff basics