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Mastiff puppies and dogs in Clayton, Ohio

Looking for a Mastiff puppy or dog in Clayton, Ohio? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Clayton, Ohio

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Clayton, Ohio

These Mastiffs are available for adoption close to Clayton, Ohio.
Photo of Cassian

Cassian

Mastiff

Male, 3 yrs 3 mos
Xenia, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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Photo of Della

Della

Mastiff

Female, 2 yrs 7 mos
Lebanon, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
I`m a girl who wins hearts with one look from my soft, gentle eyes and my permanently adorable face. I love the simple things, long naps curled up somewhere cozy, quietly staying close to my favorite people, and getting far too excited the moment I hear a treat bag crinkle. I`m sweet-natured, affectionate, and always ready to offer calm companionship, whether we`re relaxing together or enjoying a peaceful afternoon. If your idea of perfection includes a loyal cuddle buddy with impeccable nap skills and a talent for making every day feel a little softer, we`ll get along just fine.
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Photo of Smudge

Smudge

Mastiff Mixed Breed (Large)

Female, 2 mos
Cincinnati, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet the "Udge" pups! These pups, named with words rhyming with their Momma Mudge's name, were born in their foster home on April 20th, 2026.  Their mom is a 95 pound Bullmastiff mix, making these guys a perfect mix of Bullmastiff and adorable!  This adorable trio will likely grow up to be large to extra large pups. At 9 weeks old, they are already weighing between 16 and 20 pounds each!  The pups have adorable loose skin and Mastiff - like wrinkles that are sure to make anyone ooh and ahh!  As they were born in their foster home, the Udge pups have had a lot of socialization!  The pups have lived in a home with other dogs, have met cats and have been handled daily by children.  They love to run and play in the yard, chasing their human foster children and then plop down for a good nap infront of the tv.  While they have not started potty training yet, they do show signs of knowing where to go to the bathroom, so their foster family thinks that potty training will come relatively easy to them!   These sweet puppies are ready for their forever families to help them grow into their silly, sweet personalities! If they seem like a fit to you - apply today!  Their adoption fees are $400 each. To adopt this animal, please visit https://www.louieslegacy.org/adopt All of our animals come spayed or neutered, up to date on age appropriate vaccinations, are microchipped, heartworm negative, current on flea/tick and heartworm prevention, dewormed, and treated for any ailments found upon veterinary examination. The adoption fee covers a portion of these services, and makes it possible for us to continue rescuing animals. For more information on the adoption fees and the adoption process, please complete our adoption application here: https://www.louieslegacy.org/adopt - an application allows us to get to know your family better so we can assess whether the animal you are interested in is a good match for your home. An application does not obligate you to adopt. Please understand that due to the volume of applications some animals receive, we are unable to contact all applicants. If your application is considered a good fit for the animal you are interested in, or even a different pet, a volunteer will give you a call as soon as possible. We are a foster based rescue and do not have a shelter location where animals can be seen during the week. Please see our Facebook page at https://www.facebook.com/LouiesLegacy for our weekly adoption album if you are interested in meeting an animal in person. Not all animals attend every adoption event, please check our Facebook page for animal event times and locations before you make a trip to meet a specific animal.
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Photo of Fudge

Fudge

Mastiff Mixed Breed (Large)

Female, 2 mos
Cincinnati, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet the "Udge" pups! These pups, named with words rhyming with their Momma Mudge's name, were born in their foster home on April 20th, 2026.  Their mom is a 95 pound Bullmastiff mix, making these guys a perfect mix of Bullmastiff and adorable!  This adorable trio will likely grow up to be large to extra large pups. At 9 weeks old, they are already weighing between 16 and 20 pounds each!  The pups have adorable loose skin and Mastiff - like wrinkles that are sure to make anyone ooh and ahh!  As they were born in their foster home, the Udge pups have had a lot of socialization!  The pups have lived in a home with other dogs, have met cats and have been handled daily by children.  They love to run and play in the yard, chasing their human foster children and then plop down for a good nap infront of the tv.  While they have not started potty training yet, they do show signs of knowing where to go to the bathroom, so their foster family thinks that potty training will come relatively easy to them!   These sweet puppies are ready for their forever families to help them grow into their silly, sweet personalities! If they seem like a fit to you - apply today!  Their adoption fees are $400 each. To adopt this animal, please visit https://www.louieslegacy.org/adopt All of our animals come spayed or neutered, up to date on age appropriate vaccinations, are microchipped, heartworm negative, current on flea/tick and heartworm prevention, dewormed, and treated for any ailments found upon veterinary examination. The adoption fee covers a portion of these services, and makes it possible for us to continue rescuing animals. For more information on the adoption fees and the adoption process, please complete our adoption application here: https://www.louieslegacy.org/adopt - an application allows us to get to know your family better so we can assess whether the animal you are interested in is a good match for your home. An application does not obligate you to adopt. Please understand that due to the volume of applications some animals receive, we are unable to contact all applicants. If your application is considered a good fit for the animal you are interested in, or even a different pet, a volunteer will give you a call as soon as possible. We are a foster based rescue and do not have a shelter location where animals can be seen during the week. Please see our Facebook page at https://www.facebook.com/LouiesLegacy for our weekly adoption album if you are interested in meeting an animal in person. Not all animals attend every adoption event, please check our Facebook page for animal event times and locations before you make a trip to meet a specific animal.
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Photo of Pudge

Pudge

Mastiff Mixed Breed (Large)

Male, 2 mos
Cincinnati, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Spayed or Neutered,
Story
Meet the "Udge" pups! These pups, named with words rhyming with their Momma Mudge's name, were born in their foster home on April 20th, 2026.  Their mom is a 95 pound Bullmastiff mix, making these guys a perfect mix of Bullmastiff and adorable!  This adorable trio will likely grow up to be large to extra large pups. At 9 weeks old, they are already weighing between 16 and 20 pounds each!  The pups have adorable loose skin and Mastiff - like wrinkles that are sure to make anyone ooh and ahh!  As they were born in their foster home, the Udge pups have had a lot of socialization!  The pups have lived in a home with other dogs, have met cats and have been handled daily by children.  They love to run and play in the yard, chasing their human foster children and then plop down for a good nap infront of the tv.  While they have not started potty training yet, they do show signs of knowing where to go to the bathroom, so their foster family thinks that potty training will come relatively easy to them!   These sweet puppies are ready for their forever families to help them grow into their silly, sweet personalities! If they seem like a fit to you - apply today!  Their adoption fees are $400 each. To adopt this animal, please visit https://www.louieslegacy.org/adopt All of our animals come spayed or neutered, up to date on age appropriate vaccinations, are microchipped, heartworm negative, current on flea/tick and heartworm prevention, dewormed, and treated for any ailments found upon veterinary examination. The adoption fee covers a portion of these services, and makes it possible for us to continue rescuing animals. For more information on the adoption fees and the adoption process, please complete our adoption application here: https://www.louieslegacy.org/adopt - an application allows us to get to know your family better so we can assess whether the animal you are interested in is a good match for your home. An application does not obligate you to adopt. Please understand that due to the volume of applications some animals receive, we are unable to contact all applicants. If your application is considered a good fit for the animal you are interested in, or even a different pet, a volunteer will give you a call as soon as possible. We are a foster based rescue and do not have a shelter location where animals can be seen during the week. Please see our Facebook page at https://www.facebook.com/LouiesLegacy for our weekly adoption album if you are interested in meeting an animal in person. Not all animals attend every adoption event, please check our Facebook page for animal event times and locations before you make a trip to meet a specific animal.
Photo of ATLAS

ATLAS

American Pit Bull Terrier Mastiff

Male, 1 yr 6 mos
Dayton, OH
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
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Related breeds in Clayton, Ohio

Mastiff shelters & rescues in Clayton, Ohio

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Clayton, Ohio. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

22.9 miles

Greene County Animal Care and Control

641 Dayton-Xenia Rd, Xenia, OH 45385

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

28.8 miles

Humane Association of Warren County

230 Cook Rd, Lebanon, OH 45036

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Rescue

46.1 miles

Louie's Legacy Animal Rescue

Cincinnati, OH 45247

Pet Types: cats, dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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