Mastiff Adoption in Franklin, OH: Mastiff Puppies for Sale in Franklin, OH

Adopt a Mastiff near you in Franklin, Ohio

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Franklin, Ohio

These Mastiffs are available for adoption close to Franklin, Ohio.

Dexi

Mastiff

Female, Puppy

Germantown, OH

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with kids, Good with dogs, Spayed or Neutered,

Story

Meet Our Sweet Brindle Girl, Dexi! This adorable 8-month-old brindle mastiff mix puppy with the cutest floppy ears is pure love wrapped in fur! She has the sweetest personality and is happiest when she’s surrounded by people or playing with other dogs. She absolutely loves everyone she meets and gets along wonderfully with other pups, making her a perfect addition to a home with furry siblings. When she’s not making new friends, you’ll find her happily playing with her toys, enjoying a good meal, or snuggling with her foster family. She’s currently living with her two dog foster siblings, and she loves them so much! They’ve helped show her how fun life can be, and she’s ready to bring that same joy to her very own forever family. All of our dogs are spayed or neutered, up to date on age appropriate vaccinations, microchipped and if over 6 months of age, heartworm tested and on heartworm preventative in their foster home. We require an approved application to meet any of our dogs. We do not have a shelter location and will not arrange a meeting without an approved application. We strive to make sure the bios provided for our dogs are complete and accurate; we do understand that mistakes happen, however, so if you absolutely cannot find the answer to your question in the dog's bio, you can contact us for more information. We require a home visit for each dog we adopt out, so we adopt within a 2 hour radius of Dayton, OH. If you are outside of this radius, we encourage you to contact your local rescue or shelter. March 17, 2026, 5:54 pm

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Aizen

Mastiff

Male, Young

Dayton, OH

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Good with cats, House-trained, Shots are up-to-date,

Story

Aizen is one of 12 puppies born a year ago, (19 Jan 2025). We have adopted out some of his brothers and sisters. He is a big ball of fun and has a great personality and is a stocky boy like his dad. We still have his father (sire) living with me and his mother (dam) lives with my son. We still have four (4) others we are adopting as you will see on the website. Aizen is one year old, and he needs a good home soon. He is kennel trained and house trained. We originally tried to sell the puppies to recoup the high Vet bills but now we are just concerned that he gets a great, safe home. All puppy shots and vet visits are up to date with available documentation. The annual rabies shot is due soon. He is actually called, Doge de Bordeaux or French Mastiff. They are ACA registered. Heatly, active, loveable and fun to be around which make a great companion.

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Cassian

Mastiff

Male, 3 yrs

Xenia, OH

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

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Frank

Mastiff

Male, Adult

Cincinnati, OH

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Not good with kids, Good with dogs, Not good with cats, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,

Story

This is a difficult decision made with love. Our dog is a mastiff mix, about 150 lbs, and a wonderful companion, but due to his size and enthusiastic affection, he can unintentionally be unsafe around small children and elderly adults. We are seeking a home better suited to him. He is affectionate, goofy, confident, and happiest lounging near his people. He loves scratches, car rides, playing fetch (at his own pace), and laying in the sun. He is food- and praise-driven, professionally trained, and knows sit, down, stay, break, place, and heel. He mirrors the energy around him, calm environments keep him calm, while excitement can make him overly enthusiastic and mouthy (not aggressive). He enjoys short walks but tires easily and can get excited by other dogs on leash. He does well with large dogs but not small dogs or cats. Ideally, he would be the only pet. A calm home with experienced large-dog owners, a fenced yard, and a consistent routine would be ideal.❤️

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Ralph BW

Mastiff Mixed Breed (Large)

Male, 1 yr 1 mo

Cincinnati, OH

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Good with cats, Spayed or Neutered,

Story

Ralph the Derp! Ralph is a huge friendly, enthusiastic, uncoordinated 4-legged energetic goofball! He was rescued from “death row” at a high kill shelter, as a skinny stray with a treatable skin condition. His fur has almost completely grown in & he is now at a healthy weight. This overgrown mastiff/Cane Corso mix pup has no comprehension of his size, leaning into humans for affection or trying to ooze onto laps for cuddles. He is being trained not to jump and not to paw for attention/affection/play because he currently has 85# of mass behind those “congenial” moves. Ralph plays well with dogs of all sizes, but would do best with med-to-larger dogs due to his size & poorly curbed gusto. He hordes toys, taking them all to his chosen dog bed of the day. He likes to carry a special toy “baby” in his mouth when going out in the yard. He does need to be fed in his crate & will guard his empty food bowl from other dogs, unless he is distracted with a toy & led outdoors after meals. He is great on a leash, makes awesome grunty sounds when cuddled, enjoys baths. Ralph will make a great addition to an active family with older children. He is eager to please, food and affection oriented (although a bit stubborn at times), making him an ideal candidate for success with continuation of his training. Please consider adopting the gorgeous big derp into your home. Attributes: In training to avoid jumping/pawing Active family He is neutered, microchipped, had recent cherry eye repair and up to date on all vaccines and preventions. Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)

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Luke AG

Mastiff American Pit Bull Terrier

Male, 4 yrs 1 mo

Cincinnati, OH

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,

Story

Hi, I’m Luke, and I’m a big, lovable boy tipping the scales at just over 100 lbs! Don’t let my size fool you—I’m a happy, easygoing pup who just wants to play, explore, and cuddle. I’m all about the good things in life: squeaky toys, water play, long walks, and best of all—snuggle time on the couch. I’m a pro at giving hugs (though I’m working on not jumping up too hard to give them—oops!). I get along great with other dogs and kids, but because of my size and enthusiasm, I’d do best with older children who won’t get accidentally knocked over during playtime. I’m crate trained, housebroken, and walk nicely on a leash—unless there’s a squirrel… then it’s game on! I do have a slight prey drive, so a little guidance goes a long way. If you’re looking for a big-hearted, playful companion to fill your home with love (and maybe take up some space on your couch), I’m your guy. Let’s make forever happen! 🐾 Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)

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Mastiff puppies and dogs in Franklin, Ohio

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Adopt a Mastiff near you in Franklin, Ohio

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Franklin, Ohio

These Mastiffs are available for adoption close to Franklin, Ohio.

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in nearby cities

Related breeds in Franklin, Ohio

Mastiff shelters & rescues in Franklin, Ohio

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog?

Mastiff basics

Mastiff basics