Mastiff Adoption in Ohio: Mastiff Puppies for Sale in Ohio

Adopt a Mastiff near you in Ohio

Below are our newest added Mastiffs available for adoption in Ohio. To see more adoptable Mastiffs in Ohio, use the search tool below to enter specific criteria!

Daisy

Mastiff

Female, 5 mos

Vienna, OH

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

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COURTESY POST: Allie

Mastiff

Female, Adult

Strongsville, OH

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Good with cats, House-trained,

Story

Allie is a 4 to 5 year old girl looking for a new home. She is very shy and timid but is also a Velcro dog. She does great with kids, cats, dogs, and even chickens! Allie just wants to play all the time, so if you’re an active family, this is your girl! Fill out an application on our website at www. Forgetmenotanimalrescue@weebly.comMay 19, 2026, 1:01 pm

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Bruno

Mastiff

Male, 1 yr 6 mos

Cleveland, OH

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

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Scoob

Mastiff/Black Mouth Cur

Male, Young

Grafton, OH

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs,

Story

🐾 Meet Scoob 🐾 🐶 1-year-old Black Mouth Cur × Mastiff mix 😄 Happy-go-lucky personality 🏫 Currently training at a local facility 🐕 Friendly with dogs 👧 Great with kids 🧑 Loves adults too ✅ Knows “sit” & “stay” (as long as you don’t go too far 😄) 🛏️ Crate trained 🚶 Walks well on leash most of the time 👃 Can pull strongly if he catches an exciting scent 💪 Needs a strong, active adopter to continue his leash training 🏠 House training in a home environment still being evaluated 🌟 Eager to learn and thrives with structure and positive guidance 🩺 Health: ✂️ Neutered; 📍 Microchipped; ❤️ Heartworm tested; 💉 Current on all vaccines, including rabies 🐶 Perfect Match: 🏃 Active lifestyle 💪 Physically strong handler ❤️ Someone ready to continue his training and help him shine Age: 1 year Adoption Fee: $300 MBR holds monthly adoption events on the 2nd Saturday of every month at Tractor Supply in Columbia Station, 24100 Royalton Road from 11 am - 2 pm. Questions can be emailed to rescue@mbrohio.com If you are interested in adopting one of our dogs, the first thing to do is submit an application for approval. All dogs available for adoption are in foster homes. Please do not visit the rescue location as it is a privately run boarding, training and grooming facility. Individual meet and greets are scheduled by appointment only for approved adopters.

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Rhonda

Mastiff/German Shepherd Dog

Female, 1 yr

Batavia, OH

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Story

Meet Rhonda: a joyful, high-energy sweetheart with a grin so big you’ll assume she’s either (1) just heard the word “walk,” (2) just found a tennis ball, or (3) plotting harmless chaos. (It’s usually all three.)Rhonda is a big, beautiful girl with an even bigger personality. She LOVES people and other dogs—she’s basically the social coordinator who shows up like, “Hi, I made us plans. We’re best friends now.”She already knows basic commands and is eager to learn more, especially if you pay in snacks. Rhonda is classic puppy energy in a grown-up body: she plays hard, loves hard, and treats every day like it’s her birthday party. “Sitting still” is not her love language—but “let’s go do something fun” absolutely is.And that smile? Her signature full, mouth-wide-open, ear-to-ear grin will brighten your whole week. It’s like her face is permanently set to “THIS IS THE GREATEST MOMENT OF MY LIFE,” even if the moment is just… you opening the fridge.Rhonda will thrive with an active family who can give her plenty of exercise, playtime, and continued training. Give her outlets and structure, and you’ll get a loyal, affectionate adventure buddy who keeps you moving—and keeps you laughing.If your dream dog is part athlete, part goofball, and 100% love, come meet Rhonda.

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Coco

Mastiff

Female, Adult

Marietta, OH

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with cats, House-trained,

Story

Coco is a beautiful 6-year old female Mastiff mix who was surrendered by her owner on May 4, 2026 for a very sad reason. Coco had been a PTSD/therapy dog for her mistress and was very much loved by her owner. Unfortunately, her mistress has experienced health issues recently and can no longer physically take care of her beloved Coco. Coco has a tan short smooth coat with cream-colored highlights on her chest, a short docked tail, and an adorable Mastiff face with dark brown eyes, tan eyebrows, dark brown/black shading on her muzzle, and short floppy ears. This sweet girl has an affectionate, easygoing personality. Coco has no known health issues, and she gets along well with cats and children. We had taken preliminary photos of Coco in her large floor crate, and she didn't seem to have any reaction to dogs who were barking in close proximity to her. These photos of Coco were taken on May 8, 2026 when HSOV Executive Director Amy Rogers accompanied her for outdoor glamour photos. Coco was the perfect lady and stayed close to Amy. It was touching to see Coco 'perk up' when she saw a car being driven into our parking area, and she seemed mesmerized while she watched the individuals getting out of their car and walking into the shelter. Many dogs have this reaction while we have them in the photo area, and it makes us sad to wonder if they think their owner might be coming to take them home. Coco is a full-figured girl who weighs 75 lbs, and she can be fairly energetic on a leash. Coco will be spayed before being adopted by her new family. Naturally we'd love to see her back in a nice home again instead of being in a shelter environment 24/7. Coco is available as a temporary foster or as a foster-to-adopt while she waits her spay procedure. Please complete/submit an HSOV foster/adoption application for approval if you would like to offer Coco either a temporary or a forever home.

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Mastiff puppies and dogs in Ohio

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Below are our newest added Mastiffs available for adoption in Ohio. To see more adoptable Mastiffs in Ohio, use the search tool below to enter specific criteria!

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Mastiff puppies and dogs in Ohio

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Adopt a Mastiff near you in Ohio

Below are our newest added Mastiffs available for adoption in Ohio. To see more adoptable Mastiffs in Ohio, use the search tool below to enter specific criteria!

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in Ohio cities

Mastiff shelters & rescues in Ohio

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog ?

Mastiff information

Mastiff basics