Mastiff Adoption in Ohio: Mastiff Puppies for Sale in Ohio

Adopt a Mastiff near you in Ohio

Below are our newest added Mastiffs available for adoption in Ohio. To see more adoptable Mastiffs in Ohio, use the search tool below to enter specific criteria!

Abby

Mastiff/Mixed Breed (Medium)

Female, 4 yrs

Avon, OH

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, House-trained,

Story

💕 Hi there… I’m Abby! 💕 I’m a 4-year-old sweetheart with a heart as big as my adorable puppy dog eyes 🥹 Life wasn’t always easy for me. I spent a long time fending for myself and dreaming 💭 about what it would be like to have a family of my very own. But those days are behind me now, and I’m ready for my happily ever after 📖🏰 Everyone says I’m the sweetest girl you’ll ever meet, and honestly… I think they might be right 🥰 My favorite thing in the whole world is being close to my people. Whether we’re snuggling on the couch 🛋️ taking a stroll 🐾 or getting cozy at bedtime 💤 I just want to be wherever you are. If you move, I’ll probably follow. If you sit down, I’ll probably join you. It’s called commitment 💕 I’m fully vetted, house trained, and working hard on my leash skills. I have wonderful manners, a gentle soul, and enough love to last a lifetime ❤️ I’d be perfectly happy soaking up all the attention as your one and only princess 👑 or I could share my kingdom with a young, friendly dog who wants to be my buddy 🐾 My rescue friends say I’m grateful for every soft bed, every belly rub, and every kind word. I don’t take love for granted… I treasure it 💝 After spending so much time on my own, all the little things mean so much to me. What I’m really looking for is a family to call my own 🏡 A place where I never have to wonder if I’m safe, loved, or wanted ever again. If you’re looking for a loyal shadow, professional cuddle expert, and best friend who will adore you with her whole heart, I think we might be a perfect match 🥹 Love, Abby 🤍🐾 P.S. I’ve spent long enough wishing for a family. Maybe my forever home is with you? 💕🥹🐾

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Onyx

Mastiff/American Pit Bull Terrier

Male, Young

Columbus, OH

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs, Not good with cats, House-trained,

Story

I'm big boy with a huge heart! My name is onyx and I am a year and a half old. I know all my basic commands and I am potty trained. My shots are up to date. I do really well with kids (live with one currently) and am really smart when it comes to training. Because of my size, I have a hard time with cats, but if time is taken, i know i can get along with them. The reason why I need to be rehomed is because my owners dont have the nessacary time to take care of me properly, and I know for a fact that I would do amazing with someone who has the proper time. I am a very intelligent boy and am very active. I love my toys, my rope, and I love to show affection to anybody despite my size. I feel as if I am good in anybody's home honestly. Hopefully, i can be in your home!

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Oslo

Mastiff/Rottweiler

Male, Adult

Akron, OH

Size

(when grown) X-Large 101 lbs (46 kg) or more

Details

Good with kids, Good with dogs, Good with cats, House-trained,

Story

I’ve had Oslo since he was 3 weeks old. My neighbor had a male Mastiff and female Rottweiler that had puppies. The mom stopped allowing the dogs to feed at 3 weeks old so my neighbor asked me to take Oslo in. I currently have a 1 year old and a newborn. Oslo is too much for me to take care of in this time of postpartum. This rehoming is no fault of his own. He’s just too energetic and taking care of 3 beings is too much for me. He loves being outside, taking walks, and swimming in ponds. He does well with baths (you might have to tell him to get in the tub a couple times but he will eventually). He currently lives with a 10 year old female dog and adores her. They both will play and he takes care of her. At one point his male litter mate lived with us for 8 months and he did fine with him. He also has experience with male puppies. Oslo is currently living with a newborn and 1 year old child and does fine with both. He’s a gentle giant until playing tug of war, then it’s game on

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Maple

Mastiff

Female, 3 mos

Brunswick, OH

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs,

Story

At a tender age of 3 months old, Maple has already endured her share of hardship. Dumped on the side of a rural road along with her siblings, Maple and her siblings were rescued by a good Samaritan. This little family was brought to a foster home where they waited for an opportunity to be transferred to a rescue(s). Sadly, this foster home was overcrowded with strays. Maple witnessed one of her siblings being attacked by a bigger dog and died from his injuries. Except for feeding times, human interaction was scarce. It is no surprise that Maple was shy with people upon arriving at Buckeye’s, but the good news is she is coming out of her shell and seeks human affections now. Maple is so sweet and you can tell she just wants to love and be loved. Maple does well with dogs. Maple is a 3.5-month-old Mastiff mix. She is looking for a home who can devote time to building her confidence and guiding her through life. We know Maple will blossom and get to live the life that she deserves. A family with older children is preferred due to her shyness.

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Einstein

Mastiff

Male, 5 mos

Grafton, OH

Size

(when grown) Large 61-100 lbs (28-45 kg)

Details

Good with kids, Good with dogs,

Story

💪 Mr. Einstein | 5 months old | 50-pound Mastiff mix powerhouse 🦴 Big boy with an even bigger love for bones and chew time 🐶 Friendly with dogs and loves humans of all ages and sizes 🎾 Toys + people = his favorite things in life 🧠 Already mastered “sit” in record time — this guy is smart and ready to learn more 🚶‍♂️ Working on his leash manners (he’s still figuring out how large he actually is) 🏡 Working hard on potty training and making progress every day 📣 Not a fan of the crate and absolutely has opinions about it, working through it with his foster mom ❤️ Sweet, goofy, and sometimes a little timid — but gaining confidence daily ⚡ Puppy energy, giant paws, and always trying his hardest to be the best boy “Big head, big paws, big heart… Einstein is ready to grow into your best friend.” DOB: 12/07/2025 Adoption Fee: $500 MBR holds monthly adoption events on the 2nd Saturday of every month at Tractor Supply in Columbia Station, 24100 Royalton Road from 11 am - 2 pm. Questions can be emailed to rescue@mbrohio.com If you are interested in adopting one of our dogs, the first thing to do is submit an application for approval. All dogs available for adoption are in foster homes. Please do not visit the rescue location as it is a privately run boarding, training and grooming facility. Individual meet and greets are scheduled by appointment only for approved adopters.

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Special Needs

Hershey

Mastiff/Boxer

Female, Young

Englewood, OH

Size

(when grown) Med. 26-60 lbs (12-27 kg)

Details

Good with kids, Good with dogs, Needs special attention, Needs experienced adopter, House-trained,

Story

Hershey is about a year and a half old and has been in foster care a majority of the time. She was taken home by someone and severely mistreated before being returned, so she has trust issues. She’s not a fan right away to men, but once she gets to know you and gets comfortable she is a sweetheart. She has been staying with a family that has a young, special needs child and another dog for a few months. She is going to need someone who has plenty of time and patience to work with her. She is house broken, and crate trained for night and when the family is not home.

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Mastiff puppies and dogs in Ohio

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Below are our newest added Mastiffs available for adoption in Ohio. To see more adoptable Mastiffs in Ohio, use the search tool below to enter specific criteria!

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Mastiff puppies and dogs in Ohio

Jump to:

Adopt a Mastiff near you in Ohio

Below are our newest added Mastiffs available for adoption in Ohio. To see more adoptable Mastiffs in Ohio, use the search tool below to enter specific criteria!

Search for a Mastiff puppy or dog

Mastiff puppies and dogs in Ohio cities

Mastiff shelters & rescues in Ohio

Looking for a specific shelter or rescue?

Want to learn more about adopting a Mastiff puppy or dog ?

Mastiff information

Mastiff basics