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Mastiff puppies and dogs in Ohio

Looking for a Mastiff puppy or dog in Ohio? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Ohio

Below are our newest added Mastiffs available for adoption in Ohio. To see more adoptable Mastiffs in Ohio, use the search tool below to enter specific criteria!
We'll also keep you updated on Leo's adoption status with email updates.
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Leo

Mastiff/Rhodesian Ridgeback

Male, Young
Columbus, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Needs experienced adopter, House-trained,
Story
Leo is a Mastiff–Ridgeback-Pittbull mix with a heart of gold. Found as a stray and nursed back to health, he’s grown into a loving, intelligent, and loyal companion. He adores other dogs, loves cuddles, and is fully house-trained. Leo is an adventurous soul who thrives in nature, enjoys camping, and has a playful, goofy personality—plus rare double dewclaws that make him extra special. He can be hesitant with new people and has shown reactivity when nervous, so he needs a patient, experienced owner who understands large breeds. Once he trusts you, he becomes the sweetest, most affectionate lap dog you’ll ever meet. Leo would do best on a farm or in a home with plenty of space to explore, play, and feel secure. He’s truly one of a kind and deserves a forever family who will love him as deeply as he loves them.
We'll also keep you updated on MOMO's adoption status with email updates.
Photo of MOMO

MOMO

Mastiff

Female, 4 yrs
Toledo, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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We'll also keep you updated on Holly...Coming Soon's adoption status with email updates.
Photo of Holly...Coming Soon

Holly...Coming Soon

Mastiff

Female, 4 yrs
Xenia, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
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We'll also keep you updated on Zeus's adoption status with email updates.
Photo of Zeus

Zeus

Mastiff

Male, 2 yrs 6 mos
Valley View, OH
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
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Story
***We are not taking inquiries on Zeus at this time***Zeus is on mandatory stray hold until the end of business 12/1/25. If you believe that this is your dog, please give us a call at 216-525-PUPS. See our website, www.cuyahogadogs.com for details about visiting.
We'll also keep you updated on Zoey's adoption status with email updates.
Photo of Zoey

Zoey

Mastiff

Female, Adult
Columbus, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, House-trained,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Zoey (fka Ruckus) came back to MTM after being adopted several years ago and her adopter recently passed away.    She is doing great in her foster home living with a toddler, 2 young kids and dogs of all sizes.   Zoey did take a bit to adjust. She is shy at first meeting, but once she settles in, she seeks attention and thrives off of routine. So if interested in meeting her, please understand, she does not show well, but given some time and patience, she will come around and show great affection.    She has begun to engage the other dogs in play and loves to spend time outside in the yard. She does well being left alone with the other dogs, with no concern of messes or destructive behavior.     She does pull on the leash and will need some help with that, but that too needs to be made part of her routine. Zoey is a low to medium energy dog and is content to just hang out. She will pick a favorite bed and that becomes her spot.    Zoey does well riding in the car, was well behaved at the vets office and doesn't mind a nail trim as long as shes being scratched at the same time.   She is potty trained and will go to the door or even come wake you if she needs to go out.    Zoey has been fully updated on vaccines and received a dental. She is ready for a new family! Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. &#226&#128&#139Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   December 5, 2025, 6:54 pm
We'll also keep you updated on Shetland (Photos 10/28/2025)'s adoption status with email updates.
Photo of Shetland (Photos 10/28/2025)

Shetland (Photos 10/28/2025)

Mastiff

Female, Adult
Marietta, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Shetland is a beautiful 4-year old+ female Mastiff mix old+ who was brought to the HSOV on October 21, 2025 by a Good Samaritan who had found her along State Route 26 in Washington County Ohio. Shetland was not wearing a collar, and she was not microchipped. This lovely girl has a tan short smooth coat with a coarse texture, a long tail, and an adorable face with soulful brown eyes, subtle black/white shading on her large muzzle, and short floppy ears. Shetland weighs 79 lbs and epitomizes the oft-used phrase 'gentle giant' (smile). Shetland walks fairly well on a leash and was ready for an outing with HSOV Volunteer Carla Perry when these photos were taken on October 28, 2025. Shetland is an accomplished 'howler' with a melodious voice which was music to Carla's ears, so naturally she offered to take Shetland for a walk and also to give her extra TLC ... And the paparazzi tagged along when she saw an opportunity to take out-of-kennel pictures of Shetland. We noticed while Shetland was enjoying her adventure that she appears to be hearing- and perhaps vision-impaired. In compliance with the Ohio Revised Code, Shetland was held for the mandatory three-day stray hold so that her family would have an opportunity to reclaim her with proof of ownership. Since she was not reclaimed, Shetland is now available for foster or foster-to-adopt. She will be spayed before an adoption is finalized. Update: Shetland went home with a foster family on November 8th who offered her a temporary home while she awaits her forever home. If you would like to meet Shetland in person, please complete an HSOV foster/adoption application for approval so that we may arrange a meet-and-greet with Shetland. Be prepared to fall in love with this big sweetheart.

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Ohio.

Mastiff puppies and dogs in Ohio cities

Mastiff Puppies near me Mastiff in Ada Mastiff in Akron Mastiff in Alliance Mastiff in Amherst Mastiff in Archbold Mastiff in Ashland Mastiff in Ashtabula Mastiff in Athens Mastiff in Aurora Mastiff in Avon Mastiff in Avon Lake Mastiff in Barberton Mastiff in Bay Village Mastiff in Beachwood Mastiff in Beavercreek Mastiff in Bedford Mastiff in Bedford Heights Mastiff in Bellaire Mastiff in Bellbrook Mastiff in Bellefontaine Mastiff in Bellevue Mastiff in Belpre Mastiff in Berea Mastiff in Bexley Mastiff in Blanchester Mastiff in Blue Ash Mastiff in Bowling Green Mastiff in Brecksville Mastiff in Broadview Heights Mastiff in Brooklyn Mastiff in Brook Park Mastiff in Brookville Mastiff in Brunswick Mastiff in Bryan Mastiff in Bucyrus Mastiff in Cambridge Mastiff in Campbell Mastiff in Canal Fulton Mastiff in Canal Winchester Mastiff in Canfield Mastiff in Canton Mastiff in Carlisle Mastiff in Celina Mastiff in Centerville Mastiff in Chardon Mastiff in Cheviot Mastiff in Chillicothe Mastiff in Cincinnati Mastiff in Circleville Mastiff in Clayton Mastiff in Cleveland Mastiff in Cleveland Heights Mastiff in Clyde Mastiff in Coldwater Mastiff in Columbiana Mastiff in Columbus Mastiff in Conneaut Mastiff in Cortland Mastiff in Coshocton Mastiff in Crestline Mastiff in Cuyahoga Falls Mastiff in Dayton Mastiff in Deer Park Mastiff in Defiance Mastiff in Delaware Mastiff in Delphos Mastiff in Dover Mastiff in Dublin Mastiff in East Cleveland Mastiff in Eastlake Mastiff in East Liverpool Mastiff in East Palestine Mastiff in Eaton Mastiff in Elyria Mastiff in Englewood Mastiff in Euclid Mastiff in Fairborn Mastiff in Fairfield Mastiff in Fairlawn Mastiff in Fairview Park Mastiff in Findlay Mastiff in Fostoria Mastiff in Franklin Mastiff in Fremont Mastiff in Gahanna Mastiff in Galion Mastiff in Garfield Heights Mastiff in Geneva Mastiff in Germantown Mastiff in Girard Mastiff in Grafton Mastiff in Grandview Heights Mastiff in Granville Mastiff in Green Mastiff in Greenfield Mastiff in Greenville Mastiff in Grove City Mastiff in Groveport Mastiff in Hamilton Mastiff in Harrison Mastiff in Heath Mastiff in Highland Heights Mastiff in Hilliard Mastiff in Hillsboro Mastiff in Hubbard Mastiff in Huber Heights Mastiff in Hudson Mastiff in Huron Mastiff in Independence Mastiff in Ironton Mastiff in Jackson Mastiff in Kent Mastiff in Kenton Mastiff in Kettering Mastiff in Kirtland Mastiff in Lakewood Mastiff in Lancaster Mastiff in Lebanon Mastiff in Lima Mastiff in Logan Mastiff in London Mastiff in Lorain Mastiff in Louisville Mastiff in Loveland Mastiff in Lyndhurst Mastiff in Macedonia Mastiff in Madeira Mastiff in Mansfield Mastiff in Maple Heights Mastiff in Marietta Mastiff in Marion Mastiff in Martins Ferry Mastiff in Marysville Mastiff in Mason Mastiff in Massillon Mastiff in Maumee Mastiff in Mayfield Heights Mastiff in Medina Mastiff in Mentor Mastiff in Mentor on the Lake Mastiff in Miamisburg Mastiff in Middleburg Heights Mastiff in Middletown Mastiff in Milford Mastiff in Monroe Mastiff in Montgomery Mastiff in Moraine Mastiff in Mount Healthy Mastiff in Mount Vernon Mastiff in Munroe Falls Mastiff in Napoleon Mastiff in Nelsonville Mastiff in New Albany Mastiff in Newark Mastiff in New Carlisle Mastiff in New Franklin Mastiff in New Lexington Mastiff in New Philadelphia Mastiff in Newton Falls Mastiff in Niles Mastiff in North Canton Mastiff in North College Hill Mastiff in North Olmsted Mastiff in North Ridgeville Mastiff in North Royalton Mastiff in Northwood Mastiff in Norton Mastiff in Norwalk Mastiff in Norwood Mastiff in Oakwood Mastiff in Oberlin Mastiff in Olmsted Falls Mastiff in Ontario Mastiff in Oregon Mastiff in Orrville Mastiff in Ottawa Mastiff in Ottawa Hills Mastiff in Oxford Mastiff in Painesville Mastiff in Parma Mastiff in Parma Heights Mastiff in Pataskala Mastiff in Pepper Pike Mastiff in Perrysburg Mastiff in Pickerington Mastiff in Piqua Mastiff in Port Clinton Mastiff in Portsmouth Mastiff in Powell Mastiff in Ravenna Mastiff in Reading Mastiff in Reynoldsburg Mastiff in Richmond Heights Mastiff in Rittman Mastiff in Riverside Mastiff in Rocky River Mastiff in Rossford Mastiff in Saint Bernard Mastiff in Saint Clairsville Mastiff in Saint Marys Mastiff in Salem Mastiff in Sandusky Mastiff in Sebring Mastiff in Seven Hills Mastiff in Shaker Heights Mastiff in Sharonville Mastiff in Sheffield Lake Mastiff in Shelby Mastiff in Sidney Mastiff in Silverton Mastiff in Solon Mastiff in South Euclid Mastiff in Springboro Mastiff in Springdale Mastiff in Springfield Mastiff in Steubenville Mastiff in Stow Mastiff in Streetsboro Mastiff in Strongsville Mastiff in Struthers Mastiff in Sylvania Mastiff in Tallmadge Mastiff in Tiffin Mastiff in Tipp City Mastiff in Toledo Mastiff in Toronto Mastiff in Trenton Mastiff in Trotwood Mastiff in Troy Mastiff in Twinsburg Mastiff in Uhrichsville Mastiff in Union Mastiff in University Heights Mastiff in Upper Arlington Mastiff in Upper Sandusky Mastiff in Urbana Mastiff in Vandalia Mastiff in Van Wert Mastiff in Vermilion Mastiff in Wadsworth Mastiff in Wapakoneta Mastiff in Warren Mastiff in Warrensville Heights Mastiff in Washington Court House Mastiff in Waterville Mastiff in Wauseon Mastiff in Waverly Mastiff in Wellington Mastiff in Wellston Mastiff in West Carrollton Mastiff in Westerville Mastiff in Westlake Mastiff in West Milton Mastiff in Whitehall Mastiff in Wickliffe Mastiff in Willard Mastiff in Willoughby Mastiff in Willoughby Hills Mastiff in Willowick Mastiff in Wilmington Mastiff in Wooster Mastiff in Worthington Mastiff in Wyoming Mastiff in Xenia Mastiff in Youngstown Mastiff in Zanesville

Mastiff shelters & rescues in Ohio

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Ohio. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Adaline Pets Rescue

Cleveland Ohio , OH 44119

Pet Types: dogs

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Shelter

Cuyahoga County Animal Shelter

9500 Sweet Valley Drive, Valley View , OH 44125

Pet Types: dogs

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Shelter

Humane Society of Summit County

7996 Darrow Road, Suite 30, Twinsburg , OH 44087

Pet Types: cats, dogs, rabbits, small animals

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Rescue

Buckeye's Mission

4866 Center Rd, Brunswick , OH 44212

Pet Types: cats, dogs

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Rescue

R.E.A.L Rottweiler Rescue

Avon , OH 44011

Pet Types: dogs

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Shelter

Summit County Animal Control

250 Opportunity Parkway, Akron , OH 44307

Pet Types: cats, dogs

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Rescue

The Red Barn Goofy Newfy Rescue

Warren , OH 44481

Pet Types: dogs

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Shelter

Animal Welfare League

812 Youngstown Kingsville Rd. SE, Vienna , OH 44473

Pet Types: cats, birds, dogs, farm animals, rabbits, reptiles, small animals

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Rescue

Pitter Pat Junction, OH transport

Burbank transport , OH 44214

Pet Types: dogs

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Rescue

Save A Mom Pregnant Dog Rescue, Inc.

10021 Cleveland Ave SE, Magnolia , OH 44626

Pet Types: dogs

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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