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Mastiff puppies and dogs in Harrison, Ohio

Looking for a Mastiff puppy or dog in Harrison, Ohio? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Harrison, Ohio

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Harrison, Ohio

These Mastiffs are available for adoption close to Harrison, Ohio.
We'll also keep you updated on Bear's adoption status with email updates.
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Bear

Mastiff

Male, Adult
Hamilton, OH
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, Needs experienced adopter, House-trained, Shots are up-to-date,
Story
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We'll also keep you updated on Ralph BW's adoption status with email updates.
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Ralph BW

Mastiff Mixed Breed (Large)

Male, 1 yr 2 mos
Cincinnati, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
Ralph the Derp! Ralph is a huge friendly, enthusiastic, uncoordinated 4-legged energetic goofball! He was rescued from “death row” at a high kill shelter, as a skinny stray with a treatable skin condition. His fur has almost completely grown in & he is now at a healthy weight. This overgrown mastiff/Cane Corso mix pup has no comprehension of his size, leaning into humans for affection or trying to ooze onto laps for cuddles. He is being trained not to jump and not to paw for attention/affection/play because he currently has 85# of mass behind those “congenial” moves. Ralph plays well with dogs of all sizes, but would do best with med-to-larger dogs due to his size & poorly curbed gusto. He hordes toys, taking them all to his chosen dog bed of the day. He likes to carry a special toy “baby” in his mouth when going out in the yard. He does need to be fed in his crate & will guard his empty food bowl from other dogs, unless he is distracted with a toy & led outdoors after meals. He is great on a leash, makes awesome grunty sounds when cuddled, enjoys baths. Ralph will make a great addition to an active family with older children. He is eager to please, food and affection oriented (although a bit stubborn at times), making him an ideal candidate for success with continuation of his training. Please consider adopting the gorgeous big derp into your home. Attributes: In training to avoid jumping/pawing Active family He is neutered, microchipped, had recent cherry eye repair and up to date on all vaccines and preventions. Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)
We'll also keep you updated on Luke AG's adoption status with email updates.
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Luke AG

Mastiff American Pit Bull Terrier

Male, 4 yrs 2 mos
Cincinnati, OH
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats, Spayed or Neutered,
Story
Hi, I’m Luke, and I’m a big, lovable boy tipping the scales at just over 100 lbs! Don’t let my size fool you—I’m a happy, easygoing pup who just wants to play, explore, and cuddle. I’m all about the good things in life: squeaky toys, water play, long walks, and best of all—snuggle time on the couch. I’m a pro at giving hugs (though I’m working on not jumping up too hard to give them—oops!). I get along great with other dogs and kids, but because of my size and enthusiasm, I’d do best with older children who won’t get accidentally knocked over during playtime. I’m crate trained, housebroken, and walk nicely on a leash—unless there’s a squirrel… then it’s game on! I do have a slight prey drive, so a little guidance goes a long way. If you’re looking for a big-hearted, playful companion to fill your home with love (and maybe take up some space on your couch), I’m your guy. Let’s make forever happen! 🐾 Local adoption fee is $200(in TX) Out of state adoption fee is $450 (includes transport to your area)
We'll also keep you updated on Finn AKA Gage JuM's adoption status with email updates.
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Finn AKA Gage JuM

Mastiff Shepherd (Unknown Type)

Male, 7 yrs 1 mo
Cincinnati, OH
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
Finn may look like a rockstar with his striking Mastiff–Shepherd good looks, but at heart, he’s a big, soft lovebug. Weighing in at about 60 pounds, Finn has grown into a handsome boy with a beautiful gray and tan coat, soulful eyes, and an even bigger personality. Despite his star-quality appearance, Finn is more of a laid-back, easygoing guy—think Eeyore vibes, but with engines revved and ready to love. From the moment he wakes up, he’s prepared to shower his people with affection… and trust us, it’s A LOT of love! Finn does well with other dogs and does need a slow, proper introductions to new friends—both two-legged and four-legged. Once he knows you, he loves you deeply. He’s happiest when he has a buddy (human or canine) to share his world with. Affection is Finn’s specialty. When someone comes to greet him, he lights up, runs over with enthusiasm, and hands out slobbery kisses and big hugs like they’re backstage passes. His joy is genuine, his heart is huge, and he’s always thrilled to see his people. If you’re looking for a big, lovable, slightly goofy rockstar who will adore you endlessly, Finn is ready to take center stage in your heart. Local adoption only $200 (in TX)
We'll also keep you updated on Dexi's adoption status with email updates.
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Dexi

Mastiff

Female, Puppy
Germantown, OH
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with kids, Good with dogs, Spayed or Neutered,
Story
Meet Our Sweet Brindle Girl, Dexi! This adorable 9-month-old brindle mastiff mix puppy with the cutest floppy ears is pure love wrapped in fur! She has the sweetest personality and is happiest when she’s surrounded by people or playing with other dogs. She absolutely loves everyone she meets and gets along wonderfully with other pups, making her a perfect addition to a home with furry siblings. When she’s not making new friends, you’ll find her happily playing with her toys, enjoying a good meal, or snuggling with her foster family. She’s currently living with her two dog foster siblings, and she loves them so much! They’ve helped show her how fun life can be, and she’s ready to bring that same joy to her very own forever family. All of our dogs are spayed or neutered, up to date on age appropriate vaccinations, microchipped and if over 6 months of age, heartworm tested and on heartworm preventative in their foster home. We require an approved application to meet any of our dogs. We do not have a shelter location and will not arrange a meeting without an approved application. We strive to make sure the bios provided for our dogs are complete and accurate; we do understand that mistakes happen, however, so if you absolutely cannot find the answer to your question in the dog's bio, you can contact us for more information. We require a home visit for each dog we adopt out, so we adopt within a 2 hour radius of Dayton, OH. If you are outside of this radius, we encourage you to contact your local rescue or shelter.   April 24, 2026, 7:23 pm
We'll also keep you updated on Cash's adoption status with email updates.
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Cash

Mastiff

Male, 3 yrs 6 mos
Butler, KY
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Spayed or Neutered,
Story
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These pups are in Harrison, Ohio too!

Below are our newest added Mastiffs available for adoption in Harrison, Ohio. To see more adoptable Mastiffs in Harrison, Ohio, use the search tool below to enter specific criteria!
We'll also keep you updated on Remi's adoption status with email updates.
Photo of Remi

Remi

St. Bernard

Female, Young
Harrison, OH
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Needs experienced adopter, House-trained, Spayed or Neutered, Shots are up-to-date,
Story
Remi is 1 year 3 months old, 130 pounds. She has been to puppy training, house trained, and crate trained. She can sit, lay, stay, come when called, heel, and leash trained, Unfortunately Remi has started resource guarding with our other dogs. We have spoke with our Vet and this is common with this age and breed of dog. With additional training she should be able to work through this behavoir. Out of growing concern for our other 2 small dogs we believe it would be best if she was in a only dog home. She has been fine around dogs outside of our home (big or small), she often lays down to greet them. She has never been around small kids but has always been very friendly to anyone she meets. She has a very sweet and funny personality. Couch potato most of the time. She is still young so spurts of puppy energy is to be expected. Best if you have time and room for a XL breed. Continued training would be recommended as she is not done growing. She is up to date on all shots.

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Mastiff shelters & rescues in Harrison, Ohio

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Harrison, Ohio. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

17.1 miles

God's Dogs Rescue of TX in Ohio Transport Stop

Cincinnati, OH 41073

Pet Types: dogs

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Rescue

32.6 miles

Adopt A Pit Rescue

PO Box 137, Germantown, OH 45327

Pet Types: dogs

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Shelter

38.7 miles

Pendleton County Animal Shelter

1314 Byran Griffin Rd, Butler, KY 41006

Pet Types: dogs

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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