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Mastiff puppies and dogs in Mechanicsburg, Pennsylvania

Looking for a Mastiff puppy or dog in Mechanicsburg, Pennsylvania? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Mechanicsburg, Pennsylvania

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These Mastiffs are available for adoption close to Mechanicsburg, Pennsylvania.
We'll also keep you updated on Moose's adoption status with email updates.
Photo of Moose

Moose

Mastiff

Male
Harrisburg, PA
Size
(when grown) -
Details
Good with kids, Not good with dogs, Not good with cats, House-trained, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Meet Moose! This beautiful boy is a sweet and lovable friend who wants nothing more than to love and be loved. He’s come a long way since he first came to us. Initially seriously underweight at only 80 pounds with signs of neglect – he was likely locked in a crate with no padding for much of his life. Today he’s 104 pounds of sweet goofiness. He loves to nap, chew on his toys, go for walks, and thump his tail on the ground whenever you enter the room, or speak in a high voice… or say his name.  Likes: Moose is especially fond of people. He’s never met a person he doesn’t instantly love, and the feeling seems to be mutual. He wants to say hi to every neighbor he sees on his walks, and they’re all eager to oblige. Every vet, vet tech, or crew at the day care he occasionally goes to adore him. Moose also loves to chase and pounce on his big indestructible ball and is especially fond of chewing on his Nylabone. He’s also very fond of small backyard creatures – birds, squirrels, rabbits. Great news if you have a pesky groundhog in your yard, but you do need to be aware and on guard while walking him. Dislikes: Moose does not like to be left alone. His history of neglect and being left in a crate has led to separation anxiety. He is showing signs of growing confidence, however. He frequently seeks out his crate during the day to nap and he sleeps in an open crate every night in the bedroom. He is also comfortable going into another room and lying down by himself – he’s less and less of a Velcro dog all the time. Personality: Moose is a love bug. He has a very sweet personality and wants to please. He can be very playful and make one laugh out loud as he twists his big body into all different shapes for belly rubs. He’s pretty chill in the house – he loves to nap and chew on toys and doesn’t get into things or chew things he shouldn’t. Though he does seem to find the random sock! He’s very excited to welcome visitors – giving everyone a big “hello” and is then content to chew on his bone. Energy level: Moose has a few short bursts of playful energy during the day and is content with three short walks a day. His current foster doesn't have a fenced yard, but if they did, he’d likely only need a morning and evening walk, with a little playtime in the yard. Not good with: Given Moose’s interest in small backyard creatures, he’d likely not do well with cats or small dogs. He once lived with his older sister, but it's unclear if he’s had any other experience with dogs and he has not been tested with other dogs. Housetrained: Moose is completely housetrained. In fact, he seems to have an enormous bladder! Crate trained: Moose is re-learning to not fear a crate. Fence: Moose would do well with a fenced yard so he can freely play with his big indestructible ball and have plenty of safe space for sunbathing. Leash walking: Moose loves going for walks and he's been worked with quite a bit to mitigate his high prey drive. He’s learned a lot! He is walking at a heel, sitting whenever we stop walking, and beginning again with the “OK” command. He still needs work to keep from pulling when he sees a squirrel because he is very strong, but he’s getting better every day at staying more focused when he gets distracted. Hot dogs are a big motivator! Medical issues: Moose had a corneal ulcer resulting from an errant eyelash. It has healed completely. He will be checked again in two months to make sure it hasn’t returned. While initially underweight, Moose is now at a good weight of 104. The best home for Moose: Moose would do best in a home where people are home most of the day. He is an excellent work-from-home companion and really likes to be with people as much as possible. He would be great with older kids to snuggle and play with and with dog parents who can patiently continue to work on training. He is such a good boy and wants so much to have a home with people he can love. Moose is a dog with incredible potential and so deserving of a forever home. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Adopters must have their primary residence in one of the following states: Pennsylvania, Ohio, New Jersey, Delaware, Maryland, West Virginia, Virginia, and parts of North Carolina. We will not adopt giant breed dogs to renters. Homes with children under 6 years of age will not be approved for adoption. Homes with children should have a fenced yard. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845Click here to watch a video of Moose.Visit this organization's web site to see any additional information available about this pet.   June 6, 2025, 10:41 am
We'll also keep you updated on Izzabella's adoption status with email updates.
Photo of Izzabella

Izzabella

English Mastiff

Female, Senior
Harrisburg, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application HEADLINER: Izzabella aka Izzy. HISTORY: One owner who did not provide basic medical care so Izzy lived many year with out of control skin issues, ear infections, UTI’s, etc. PERSONALITY: Izzy is a sweet, friendly girl that loves meeting new people and welcoming them into the house. She loves attention and affection and will lean in hard for pets and ear scratches. She tends to spend her days snoozing away but when she gets the zoomies she takes them seriously and this girl can move despite her age.  She lives peacefully with a 60lb male mixed breed but is reactive when seeing dogs out on a walk. Izzy is a bit fearful of fireworks and thunderstorms and will sometimes get spooked by loud noises. Izzy likes things to happen on her own personal timeline and can be stubborn when they don’t. She will test limits by whining and carrying on (dancing around, stomping her feet, wagging her tail furiously while staring at you) to try to get her way. She’s learning that those things don’t work in our house but it’s hard not to laugh at her antics. She’ll do it to the other dog in the house too when he’s laying in a bed that she wants. She usually gets her way with the dog.  FAVORITE ACTIVITIES: Napping, soaking up love and attention, laying in the sun MEDICAL ISSUES: With vet care and a quality diet Izzy’s skin issues and ear infections have cleared up and she is no longer a big itchy mess. She did have a mammary tumor removed while being spayed. She is not currently on any medications. WHAT WOULD BE THE BEST KIND OF HOME: Izzy enjoys hanging out with her people, so a family that spends a lot of time around the house/yard/garden would be great for her. Once integrated with another dog she is very polite and respectful but she definitely needs slow introductions to new dogs. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Adopters must have their primary residence in one of the following states: Pennsylvania, Ohio, New Jersey, Delaware, Maryland, West Virginia, Virginia, and parts of North Carolina. We will not adopt giant breed dogs to renters. Homes with children under 6 years of age will not be approved for adoption. Homes with children should have a fenced yard. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845Visit this organization's web site to see any additional information available about this pet.   November 3, 2024, 10:55 pm
We'll also keep you updated on Konik's adoption status with email updates.
Photo of Konik

Konik

Mastiff Shepherd (Unknown Type)

Male, Puppy
Harrisburg, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Not good with cats, House-trained, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application HEADLINER: Konik earns his name any time he meets a human; he is a licker. He is also a cuddler and a lap dog. He loves all humans and is great with dogs of all sizes. He is being fostered on a farm with four other dogs ranging from 20 to 130 pounds and does fine with them all. His best friend is a Great Dane who he loves to play chase and keep away with. They will play outside then curl up on the couch together for a good, long nap. HISTORY: Konik was found as a stray by three teenagers. Each boy took him home but was told no by the parents. Thankfully the third boy’s grandma took Konik to the local dog shelter who reached out to find a rescue for him. PERSONALITY: Konik has the sweetest personality. Just an absolute cuddle bug. He is young, playful, well-behaved and eager to please. He does not have a prey drive and doesn’t show any aggression. He has met outside cats and is curious; he will chase but in play not to harm. FAVORITE ACTIVITIES: Konik loves toys, especially chew toys. He’ll play keep away and tug of war, but he also plays quietly by himself. He loves to romp and play outside with his Great Dane friend then nap for a few hours on a couch. He also loves to be around people. Going to the kitchen? He’ll tag along. Going to the bathroom? Well obviously, you need company. MEDICAL ISSUES: None. He’s been neutered is UTD on vaccines, is heart worm negative and on preventative WHAT WOULD BE THE BEST KIND OF HOME: Konik just wants to be loved. He’s great with other dogs but is just as happy hanging with the humans and he’s great with kids. He just lights up around children. Konik is young, athletic and needs to know where his family is. He can clear a baby gate or a 5’ fence so needs to be on a leash or watched while he’s learning his new surroundings. He is a smart dog and learns quickly. Once taught he will respect gates and boundaries. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. **Puppy Adoption Policy: To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Adopters will be required to enroll the puppy into training and provide proof to Mastiffs To Mutts Rescue within 6 months of adopting.  Certain large-breed dogs should not be sterilized before 12 - 18 months of age. If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed. If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  Important notes before applying. Adopters must have their primary residence in one of the following states: Pennsylvania, Ohio, New Jersey, Delaware, Maryland, West Virginia, Virginia, and parts of North Carolina. We will not adopt giant breed dogs to renters. Homes with children under 6 years of age will not be approved for adoption. Homes with children should have a fenced yard. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845Click here to watch a video of Konik.Visit this organization's web site to see any additional information available about this pet.   April 17, 2025, 8:27 pm
We'll also keep you updated on Bruno's adoption status with email updates.
Photo of Bruno

Bruno

Mastiff

Male, Young
York transport, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Not good with cats, Spayed or Neutered, Shots are up-to-date,
Story
You can fill out an adoption application online on our official website.Thank you for checking out our wonderful orphans. If you would like to find out more please email or call Diane at...diane@ulpr.org or 870-577-3744.   Please email us at  diane@ulpr.org  and request an application.Visit this organization's web site to see any additional information available about this pet.October 27, 2024, 7:39 pm
We'll also keep you updated on Hagrid's adoption status with email updates.
Photo of Hagrid

Hagrid

Mastiff

Male, 5 yrs 9 mos
York, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with kids, Not good with dogs, Not good with cats, Spayed or Neutered,
Story
Meet Hagrid! This lovable big boy has plenty of affection (and drool!) to share. He’s still working on filling out, but his heart is already full of love. Hagrid would do best with a family that can handle his size and strength and is ready for a loyal companion who’s as sweet as he is sturdy.
We'll also keep you updated on Blondie's adoption status with email updates.
Photo of Blondie

Blondie

Mastiff Husky

Female, 9 mos
York, PA
Size
(when grown) -
Details
Not good with kids, Good with dogs, Not good with cats, Spayed or Neutered,
Story
Meet Blondie! This sweet, shy girl just wants to be loved and maybe curl up in your lap, too! Blondie may be a little nervous at first, but with time, patience, and lots of affection, she’ll blossom into the loving companion she’s meant to be. She’s ready to find her person!

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Mastiff shelters & rescues in Mechanicsburg, Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Mechanicsburg, Pennsylvania. Browse these Mastiff rescues and shelters below.

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Rescue

12.1 miles

Mastiffs To Mutts - Central PA

Harrisburg, PA 17109

Pet Types: dogs

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Rescue

23.9 miles

Pitter Pat Junction, York PA transport

York transport, PA 17403

Pet Types: dogs

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Shelter

25.3 miles

York County SPCA

3159 Susquehanna Trail North, York, PA 17406

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Mastiff basics

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