Adopt

Mastiff puppies and dogs in Pennsylvania

Looking for a Mastiff puppy or dog in Pennsylvania? Adopt a Pet can help you find an adorable Mastiff near you.

Picture of Mastiff

Adopt a Mastiff near you in Pennsylvania

Below are our newest added Mastiffs available for adoption in Pennsylvania. To see more adoptable Mastiffs in Pennsylvania, use the search tool below to enter specific criteria!
new badge
Photo of Mollie

Mollie

Mastiff/Mixed Breed (Medium)

Female, 1 yr 1 mo
Pittsburgh, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Got a big home and a big heart? Why not add in a big dog as well? At over 70 lbs. Mollie is just that! She came to the shelter as a stray, and recently came back to us due to her size and strength. She's got a larger-than-life personality and is very wiggly and high-energy! She loves toys, and loves to zoom around everywhere, whether it's a yard or while running on a walk! Because of her size, strength, and protective tendencies, she will need an experienced dog owner who is able to handle her and use positive reinforcement to ensure she's the best-behaved version of herself that she possibly can be. She can be a bit selective of her dog friends, and while she has enjoyed playing with certain dogs, she may not particularly enjoy dog parks or daycare. But with Mollie, you won't even want another dog, because she's DEFINETLEY doing to steal the show and be the big, slobbery, center of your universe. Come say hi to her today! Humane Animal Rescue of Pittsburgh East End- 6926 Hamilton Ave Pittsburgh, Pa 15208 Kennel License #: 1043
Photo of Delmar

Delmar

Mastiff

Male, 2 yrs
Philadelphia, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs,
Story
Delmar and Hardey https://youtu.be/me1bVZhIGew?is=TDJt1tW515fWvOM5 https://youtu.be/UvBtMmPWc0M?is=Qnpa4i4W_6fqVKuP https://youtu.be/eV70Dac34rE?is=VyULoWo1j69xgSQ1 Stiff greetings. Able to sniff and be sniffed. Handler oriented ACCT Philly is located at 111 West Hunting Park Ave in Philadelphia. We are open for adoptions 7 days a week. Please visit www.acctphilly.org/adopt for details. If you are a rescue interested in pulling this animal, please email our lifesaving team, or visit here if you are not currently a rescue partner: https://acctphilly.org/acct-philly-love-local-partnership-program/ Confirmed placement is considered a confirmation of an actual rescue pull. Possible placement, interested parties, and other "TBD" statuses are not considered confirmed and do not indicate an animal is no longer urgent. All animals at ACCT Philly are from Philadelphia, as the only open-intake animal shelter in Philadelphia, we are not able to accept animals from outside of Philadelphia. ACCT Philly's Pennsylvania kennel license number is 08313
Photo of Milo

Milo

English Mastiff

Male, Senior
Exton, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Good with cats, House-trained,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Click here to watch a video of Milo.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845  November 12, 2026, 9:55 pm
Photo of Milo

Milo

English Mastiff

Male, Senior
McDonald, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Good with cats, House-trained,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Click here to watch a video of Milo.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845  November 12, 2026, 9:55 pm
Photo of Milo

Milo

English Mastiff

Male, Senior
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with dogs, Good with cats, House-trained,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Click here to watch a video of Milo.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845  November 12, 2026, 9:55 pm
Photo of Queso

Queso

Mastiff

Female, 1 yr
Philadelphia, PA
Size
(when grown) Med. 26-60 lbs (12-27 kg)
Details
Good with dogs,
Story
Meet Queso (ACCT-A-266544)! Queso is a wonderful companion who can be a bit shy and scared at first, but she warms up easily and loves to show off her sweet, playful, and cuddly side. When she's out and about, she is known for being low-key and happy to sit in the sun soaking up gentle pets. She is easy to guide on a leash and will make a fantastic, loyal friend for someone ready to welcome her home! 📽️Videos📽️: Queso is cheesin for the camera https://youtube.com/shorts/3Du9SFwdZCY?is=ZpAqlOBDx2NI8qHw Slick & Queso https://youtu.be/4r8dPepXmGY playgroup 11/7 https://www.youtube.com/playlist?list=PLWKxXXUz1mA8 ⭐Behavioral Notes⭐: 11/09/2026: Good greetings at the fence, loose body. Face to face pulled strongly, loose body, good greetings, then play bows and spins, sniffed and was sniffed then moved away on her own. 11/07/2026: Playgroup 11/7: Mildly steerable with spray bottle (2/5) and shake can (2/5). Gate greetings: stiff mid- to high-tail, meandering around sniffing. Appropriate greets once inside the yard. Shifted into push/pull play & shuffling around, spin moves with Iso and Cadler. As time went on, increasingly tended to (over)correct for space. Repeatedly corrected Cadler for vertical, up-close play with barks and bared teeth, but didn't push into his space and stopped when he backed off. Later briefly corrected Kolli & Tyrone in the same manner. Strongly corrected either Kilo or Iso for attempting to mount. Removed shortly afterward. 11/07/2026: Per Volunteer 11/7: Queso is very sweet and low key. Easy to guide on the leash. Happy to sit in the sun and get pets. 11/07/2026: Kennel Presentation: ACA did not feel comfortable getting out of the crate for playgroup. reported she was hard barking and lunging at the front. When I approached she was hard barking with ears to the side and mid tail slowly wagging. Leash Skills: Easy to leash and came right out of the kennel. Pulls mildly on the leash and pulled harder once outside. Sociability: Tolerant of the gentle pets however did not solicit pets from me. Play: n/a Dog Interaction: In playgroup 11.7 Return to Kennel: Clip the leash out an abundance of caution. Went right into kennel and slipped the leash off. Color Level: Blue ACCT Philly is located at 111 West Hunting Park Ave in Philadelphia. We are open for adoptions 7 days a week. Please visit www.acctphilly.org/adopt for details. If you are a rescue interested in pulling this animal, please email our lifesaving team, or visit here if you are not currently a rescue partner: https://acctphilly.org/acct-philly-love-local-partnership-program/ Confirmed placement is considered a confirmation of an actual rescue pull. Possible placement, interested parties, and other "TBD" statuses are not considered confirmed and do not indicate an animal is no longer urgent. All animals at ACCT Philly are from Philadelphia, as the only open-intake animal shelter in Philadelphia, we are not able to accept animals from outside of Philadelphia. ACCT Philly's Pennsylvania kennel license number is 08313

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Pennsylvania.

Mastiff puppies and dogs in Pennsylvania cities

Mastiff Puppies near me Mastiff in Aliquippa Mastiff in Allentown Mastiff in Altoona Mastiff in Ambler Mastiff in Ambridge Mastiff in Archbald Mastiff in Arnold Mastiff in Avalon Mastiff in Bangor Mastiff in Beaver Mastiff in Beaver Falls Mastiff in Bellefonte Mastiff in Bellevue Mastiff in Berwick Mastiff in Bethel Park Mastiff in Bethlehem Mastiff in Birdsboro Mastiff in Blakely Mastiff in Bloomsburg Mastiff in Braddock Mastiff in Bradford Mastiff in Brentwood Mastiff in Bridgeport Mastiff in Bridgeville Mastiff in Bristol Mastiff in Brookhaven Mastiff in Butler Mastiff in California Mastiff in Camp Hill Mastiff in Canonsburg Mastiff in Carbondale Mastiff in Carlisle Mastiff in Carnegie Mastiff in Castle Shannon Mastiff in Catasauqua Mastiff in Chambersburg Mastiff in Charleroi Mastiff in Chester Mastiff in Clairton Mastiff in Clarion Mastiff in Clarks Summit Mastiff in Clearfield Mastiff in Clifton Heights Mastiff in Coatesville Mastiff in Collegeville Mastiff in Collingdale Mastiff in Columbia Mastiff in Connellsville Mastiff in Conshohocken Mastiff in Coraopolis Mastiff in Corry Mastiff in Crafton Mastiff in Danville Mastiff in Darby Mastiff in Dickson City Mastiff in Donora Mastiff in Downingtown Mastiff in Doylestown Mastiff in Dubois Mastiff in Dunmore Mastiff in Duquesne Mastiff in Duryea Mastiff in Easton Mastiff in East Petersburg Mastiff in East Stroudsburg Mastiff in Edinboro Mastiff in Edwardsville Mastiff in Elizabethtown Mastiff in Ellwood City Mastiff in Emmaus Mastiff in Ephrata Mastiff in Erie Mastiff in Exeter Mastiff in Farrell Mastiff in Folcroft Mastiff in Fountain Hill Mastiff in Franklin Mastiff in Gettysburg Mastiff in Glassport Mastiff in Glenolden Mastiff in Greensburg Mastiff in Greenville Mastiff in Grove City Mastiff in Hanover Mastiff in Harrisburg Mastiff in Hatboro Mastiff in Hazleton Mastiff in Hellertown Mastiff in Hermitage Mastiff in Hollidaysburg Mastiff in Honesdale Mastiff in Hummelstown Mastiff in Huntingdon Mastiff in Indiana Mastiff in Jeannette Mastiff in Jefferson Hills Mastiff in Jenkintown Mastiff in Jersey Shore Mastiff in Jessup Mastiff in Jim Thorpe Mastiff in Johnstown Mastiff in Kennett Square Mastiff in Kingston Mastiff in Kittanning Mastiff in Kutztown Mastiff in Lancaster Mastiff in Lansdale Mastiff in Lansdowne Mastiff in Larksville Mastiff in Latrobe Mastiff in Lebanon Mastiff in Lehighton Mastiff in Lewisburg Mastiff in Lewistown Mastiff in Lititz Mastiff in Lock Haven Mastiff in Lower Burrell Mastiff in Mahanoy City Mastiff in Manheim Mastiff in McKeesport Mastiff in Mc Kees Rocks Mastiff in Meadville Mastiff in Mechanicsburg Mastiff in Media Mastiff in Middletown Mastiff in Millersville Mastiff in Milton Mastiff in Monaca Mastiff in Monessen Mastiff in Monongahela Mastiff in Monroeville Mastiff in Montoursville Mastiff in Moosic Mastiff in Morrisville Mastiff in Mount Carmel Mastiff in Mount Joy Mastiff in Mount Pleasant Mastiff in Munhall Mastiff in Murrysville Mastiff in Nanticoke Mastiff in Nazareth Mastiff in New Brighton Mastiff in New Castle Mastiff in New Cumberland Mastiff in New Holland Mastiff in New Kensington Mastiff in Norristown Mastiff in Northampton Mastiff in Norwood Mastiff in Oakmont Mastiff in Oil City Mastiff in Old Forge Mastiff in Olyphant Mastiff in Oxford Mastiff in Palmerton Mastiff in Palmyra Mastiff in Perkasie Mastiff in Philadelphia Mastiff in Phoenixville Mastiff in Pittsburgh Mastiff in Pittston Mastiff in Pleasant Hills Mastiff in Plum Mastiff in Plymouth Mastiff in Pottstown Mastiff in Pottsville Mastiff in Prospect Park Mastiff in Punxsutawney Mastiff in Quakertown Mastiff in Reading Mastiff in Red Lion Mastiff in Ridley Park Mastiff in Royersford Mastiff in Saint Marys Mastiff in Sayre Mastiff in Schuylkill Haven Mastiff in Scottdale Mastiff in Scranton Mastiff in Selinsgrove Mastiff in Sellersville Mastiff in Shamokin Mastiff in Sharon Mastiff in Sharon Hill Mastiff in Shenandoah Mastiff in Shillington Mastiff in Shippensburg Mastiff in Slatington Mastiff in Somerset Mastiff in Souderton Mastiff in South Williamsport Mastiff in State College Mastiff in Steelton Mastiff in Stroudsburg Mastiff in Sunbury Mastiff in Swarthmore Mastiff in Swissvale Mastiff in Swoyersville Mastiff in Tamaqua Mastiff in Tarentum Mastiff in Taylor Mastiff in Telford Mastiff in Titusville Mastiff in Turtle Creek Mastiff in Tyrone Mastiff in Uniontown Mastiff in Vandergrift Mastiff in Warren Mastiff in Washington Mastiff in Waynesboro Mastiff in West Chester Mastiff in West Mifflin Mastiff in West Pittston Mastiff in West View Mastiff in Whitehall Mastiff in White Oak Mastiff in Wilkes Barre Mastiff in Wilkinsburg Mastiff in Williamsport Mastiff in Wyomissing Mastiff in Yeadon Mastiff in York

Mastiff shelters & rescues in Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Pennsylvania. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Shelter

Lycoming County SPCA

2805 Reach Road, Williamsport , PA 17701

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

More an arrow icon

Shelter

Humane Animal Rescue - East

6926 Hamilton Ave., Pittsburgh , PA 15208

Pet Types: cats, birds, dogs, farm animals, rabbits, reptiles, small animals

More an arrow icon

Shelter

Sable Kennel

1681 5th Ave, McKeesport , PA 15132

Pet Types: dogs

More an arrow icon

Rescue

God's Dogs Rescue of TX in PA Transport Stop

Pittsburgh , PA 15106

Pet Types: dogs

More an arrow icon

Rescue

Mastiffs To Mutts - Central PA

Harrisburg , PA 17109

Pet Types: dogs

More an arrow icon

Shelter

Animal Resource Center

Millville , PA 17846

Pet Types: cats, dogs

More an arrow icon

Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

magnifying glass with cat and dog

Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

clipboard with list

Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

Learn More an arrow icon