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Mastiff puppies and dogs in Pennsylvania

Looking for a Mastiff puppy or dog in Pennsylvania? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Pennsylvania

Below are our newest added Mastiffs available for adoption in Pennsylvania. To see more adoptable Mastiffs in Pennsylvania, use the search tool below to enter specific criteria!
We'll also keep you updated on Rufio's adoption status with email updates.
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Rufio

Mastiff

Male, 6 yrs 6 mos
Harrisburg, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Rufio is a gentle soul. He is a little shy and more on the quiet side. He does good with other dogs, even small ones.I just can’t say enough sweet things about this pup. He is good in a car and is learning the leash. It takes a little while for him to trust new people, but once he does, his goofy and sweet personality shines!Rufio is medium energy and would do great with any family with a little patience. Located in Houston, Tx. Transport to most states available for an additional fee of $300.
We'll also keep you updated on Sampson's adoption status with email updates.
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Sampson

Mastiff

Male, 2 yrs
Eighty Four, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Meet `Sampson`Sampson is a 2 year old Mastiff/Pit bull mix weighing 71 pounds of love, goofiness, and gentle charm. While his size and serious look can be intimidating at first, Sampson is actually a shy, soft-hearted boy who just needs time to feel comfortable. Once he warms up, his personality truly shines. Sampson is silly and playful especially when it comes to his favorite beloved stuffies, and balls. He is also know for the sweetest hugs, leaning in close to show you his affection and trust.Sampson would do best with a strong, patient adopter who understands that first impressions aren`t everything and is willing to let him open up at his own pace. Sampson was found as a stray and will benefit from some basic manner and leash training.He will need to meet all humans and canines before adoption, and no children under 15.
We'll also keep you updated on Kodiak's adoption status with email updates.
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Kodiak

Mastiff/Mixed Breed (Large)

Male, Young
Greensburg, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Good with cats,
Story
Meet Kodiak, a gentle giant in the making with a heart as soft as his coat. This almost 6-month-old mastiff mix is tan with striking black markings around his face and the most soulful light brown eyes that stop you in your tracks. Kodiak came to rescue from animal control underweight, but he’s doing wonderfully in his foster home and steadily putting on the weight he needs. What hasn’t needed any help is his personality—he is truly the sweetest boy. He has chosen his foster mom as his person and, if given the chance, will happily lay on top of her about 95% of the time. He thrives on closeness and affection and wants nothing more than to be near his people. He already knows how to sit, learned his name quickly, and is eager to keep learning. Kodiak is very smart and picks things up fast. He is currently working on potty training and understands that outside is where he’s supposed to go, though he still has occasional accidents, mostly from excitement. He does well in a crate and continues to improve every day. Kodiak absolutely loves other dogs and cats and does great with them. He has not yet been around children, and since he’s still growing and sometimes forgets how big he is, a home that can help guide him as he matures would be ideal. As a bonus, he has the softest coat imaginable and a playful side—his favorite toys are anything with stuffing, which he proudly redistributes around the house. Kodiak is the kind of puppy that makes fostering hard, because he’s truly that special. He will make an incredibly loving, loyal companion for a home ready to grow with him and give him the stability and affection he deserves. Adoption application can be found at this link- https://airtable.com/shrAznkHf1ruIqQwq
We'll also keep you updated on Titan's adoption status with email updates.
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Titan

Mastiff

Male, Young
Allentown, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained,
Story
Titan is a 1year old English Mastiff. He loves people and kids and of course a trampoline. He is dominant with other dogs and should be separated when eatting. He will not bite if you pull his food away. Only wants the other dog food. He a big boy who loves food. He is a heavy shedder, and Im allergic. Im in no rush to rehome him. Titan is looking for a loving home who will give him the attention he needs. He needs a home with space no townhomes or apartments. I perfer to introduce him and not hand him right over. I want to make sure you really want him. Im not requiring that he is neutered. First time on this app. Completely your choice
We'll also keep you updated on Snubbull's adoption status with email updates.
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Snubbull

Mastiff/Mixed Breed (Large)

Female, 3 yrs 9 mos
York, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
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Story
Found on Penn St in York City
We'll also keep you updated on June's adoption status with email updates.
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June

English Mastiff

Female, Adult
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, House-trained,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Headliner: Meet June - your soft and fluffy Mastiff who has so much lover to share. She came to us scared and timid but within days she came out of her shell and showed us how wonderful she is and how much she wants her forever family. She is 100% love and affection. In a few short weeks at her foster home she has quickly adapted to her new routine and housemates and has been a joy to have around. Personality: Large, happy, and typical Mastiff. She wants to be with her people and pack.  She is cheerful and full of love and very, very gentle. She has moderate to low drooling which is directly tied to eating, drinking or getting overly excited. She is a gentle giant. She approaches new situations with caution and looks to her people for assurance. She is quick to overcome her hesitations and reacts well to re-direction. She isn’t sketch; just aware and cautious.   Favorite Activities: Being near to her pack, being petted, napping, and going for walks. She likes treats too…she takes them with a very gentle mouth.     Medical: Small lump on her side that is scheduled to be checked otherwise appears in great health.   Best home: Great with kids, adults, and elderly people. She gets along very well with her two house mates - a bossy female Staffordshire terrier and a large and energetic male lab. Click here to watch a video of June.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. &#226&#128&#139Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   December 26, 2025, 8:11 pm

Search for a Mastiff puppy or dog

Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Pennsylvania.

Mastiff puppies and dogs in Pennsylvania cities

Mastiff Puppies near me Mastiff in Aliquippa Mastiff in Allentown Mastiff in Altoona Mastiff in Ambler Mastiff in Ambridge Mastiff in Archbald Mastiff in Arnold Mastiff in Avalon Mastiff in Bangor Mastiff in Beaver Mastiff in Beaver Falls Mastiff in Bellefonte Mastiff in Bellevue Mastiff in Berwick Mastiff in Bethel Park Mastiff in Bethlehem Mastiff in Birdsboro Mastiff in Blakely Mastiff in Bloomsburg Mastiff in Braddock Mastiff in Bradford Mastiff in Brentwood Mastiff in Bridgeport Mastiff in Bridgeville Mastiff in Bristol Mastiff in Brookhaven Mastiff in Butler Mastiff in California Mastiff in Camp Hill Mastiff in Canonsburg Mastiff in Carbondale Mastiff in Carlisle Mastiff in Carnegie Mastiff in Castle Shannon Mastiff in Catasauqua Mastiff in Chambersburg Mastiff in Charleroi Mastiff in Chester Mastiff in Clairton Mastiff in Clarion Mastiff in Clarks Summit Mastiff in Clearfield Mastiff in Clifton Heights Mastiff in Coatesville Mastiff in Collegeville Mastiff in Collingdale Mastiff in Columbia Mastiff in Connellsville Mastiff in Conshohocken Mastiff in Coraopolis Mastiff in Corry Mastiff in Crafton Mastiff in Danville Mastiff in Darby Mastiff in Dickson City Mastiff in Donora Mastiff in Downingtown Mastiff in Doylestown Mastiff in Dubois Mastiff in Dunmore Mastiff in Duquesne Mastiff in Duryea Mastiff in Easton Mastiff in East Petersburg Mastiff in East Stroudsburg Mastiff in Edinboro Mastiff in Edwardsville Mastiff in Elizabethtown Mastiff in Ellwood City Mastiff in Emmaus Mastiff in Ephrata Mastiff in Erie Mastiff in Exeter Mastiff in Farrell Mastiff in Folcroft Mastiff in Fountain Hill Mastiff in Franklin Mastiff in Gettysburg Mastiff in Glassport Mastiff in Glenolden Mastiff in Greensburg Mastiff in Greenville Mastiff in Grove City Mastiff in Hanover Mastiff in Harrisburg Mastiff in Hatboro Mastiff in Hazleton Mastiff in Hellertown Mastiff in Hermitage Mastiff in Hollidaysburg Mastiff in Honesdale Mastiff in Hummelstown Mastiff in Huntingdon Mastiff in Indiana Mastiff in Jeannette Mastiff in Jefferson Hills Mastiff in Jenkintown Mastiff in Jersey Shore Mastiff in Jessup Mastiff in Jim Thorpe Mastiff in Johnstown Mastiff in Kennett Square Mastiff in Kingston Mastiff in Kittanning Mastiff in Kutztown Mastiff in Lancaster Mastiff in Lansdale Mastiff in Lansdowne Mastiff in Larksville Mastiff in Latrobe Mastiff in Lebanon Mastiff in Lehighton Mastiff in Lewisburg Mastiff in Lewistown Mastiff in Lititz Mastiff in Lock Haven Mastiff in Lower Burrell Mastiff in Mahanoy City Mastiff in Manheim Mastiff in McKeesport Mastiff in Mc Kees Rocks Mastiff in Meadville Mastiff in Mechanicsburg Mastiff in Media Mastiff in Middletown Mastiff in Millersville Mastiff in Milton Mastiff in Monaca Mastiff in Monessen Mastiff in Monongahela Mastiff in Monroeville Mastiff in Montoursville Mastiff in Moosic Mastiff in Morrisville Mastiff in Mount Carmel Mastiff in Mount Joy Mastiff in Mount Pleasant Mastiff in Munhall Mastiff in Murrysville Mastiff in Nanticoke Mastiff in Nazareth Mastiff in New Brighton Mastiff in New Castle Mastiff in New Cumberland Mastiff in New Holland Mastiff in New Kensington Mastiff in Norristown Mastiff in Northampton Mastiff in Norwood Mastiff in Oakmont Mastiff in Oil City Mastiff in Old Forge Mastiff in Olyphant Mastiff in Oxford Mastiff in Palmerton Mastiff in Palmyra Mastiff in Perkasie Mastiff in Philadelphia Mastiff in Phoenixville Mastiff in Pittsburgh Mastiff in Pittston Mastiff in Pleasant Hills Mastiff in Plum Mastiff in Plymouth Mastiff in Pottstown Mastiff in Pottsville Mastiff in Prospect Park Mastiff in Punxsutawney Mastiff in Quakertown Mastiff in Reading Mastiff in Red Lion Mastiff in Ridley Park Mastiff in Royersford Mastiff in Saint Marys Mastiff in Sayre Mastiff in Schuylkill Haven Mastiff in Scottdale Mastiff in Scranton Mastiff in Selinsgrove Mastiff in Sellersville Mastiff in Shamokin Mastiff in Sharon Mastiff in Sharon Hill Mastiff in Shenandoah Mastiff in Shillington Mastiff in Shippensburg Mastiff in Slatington Mastiff in Somerset Mastiff in Souderton Mastiff in South Williamsport Mastiff in State College Mastiff in Steelton Mastiff in Stroudsburg Mastiff in Sunbury Mastiff in Swarthmore Mastiff in Swissvale Mastiff in Swoyersville Mastiff in Tamaqua Mastiff in Tarentum Mastiff in Taylor Mastiff in Telford Mastiff in Titusville Mastiff in Turtle Creek Mastiff in Tyrone Mastiff in Uniontown Mastiff in Vandergrift Mastiff in Warren Mastiff in Washington Mastiff in Waynesboro Mastiff in West Chester Mastiff in West Mifflin Mastiff in West Pittston Mastiff in West View Mastiff in Whitehall Mastiff in White Oak Mastiff in Wilkes Barre Mastiff in Wilkinsburg Mastiff in Williamsport Mastiff in Wyomissing Mastiff in Yeadon Mastiff in York

Mastiff shelters & rescues in Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Pennsylvania. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Shelter

SPCA of Luzerne County

524 East Main Street, Wilkes Barre , PA 18702

Pet Types: cats, birds, dogs, farm animals, rabbits, reptiles, small animals

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Rescue

Mastiffs To Mutts - Central PA

Harrisburg , PA 17109

Pet Types: dogs

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Shelter

Huntingdon County Humane Society LC #2157

11371 School House Hollow Road, Huntingdon , PA 16652

Pet Types: cats, dogs

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Shelter

Peaceable Kingdom Shelter

1049 MacArthur Road, Whitehall , PA 18052

Pet Types: cats, dogs, rabbits, small animals

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Shelter

York County SPCA

3159 Susquehanna Trail North, York , PA 17406

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

Pitter Pat Junction, PA transport

Allentown transport , PA 18101

Pet Types: dogs

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Rescue

Pitter Pat Junction, York PA transport

York transport , PA 17403

Pet Types: dogs

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Shelter

Brandywine Valley SPCA - Lancaster

2195 Lincoln Hwy E, Lancaster , PA 17602

Pet Types: dogs

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Shelter

AWSOM

Godfrey Ridge Drive, Stroudsburg , PA 18360

Pet Types: cats, birds, dogs, rabbits, small animals

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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