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Mastiff puppies and dogs in Pennsylvania

Looking for a Mastiff puppy or dog in Pennsylvania? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Pennsylvania

Below are our newest added Mastiffs available for adoption in Pennsylvania. To see more adoptable Mastiffs in Pennsylvania, use the search tool below to enter specific criteria!
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Photo of Lola

Lola

Mastiff/Australian Cattle Dog

Female, 1 yr 3 mos
Bensalem, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Lola is a 1-year-old English Mastiff mix who is looking for someone patient enough to let her show you just how special she is. She can be a little shy at first and needs some time to warm up and learn to trust new people, but once she does, her sweet personality truly shines. Once Lola feels comfortable, she is affectionate, cuddly, playful, and absolutely loves being around her people. She’s also one smart girl! She already knows sit, paw, and down, and she’s eager to keep learning. Lola loves spending time outside, whether she’s sniffing around and taking in all the smells or having fun playing. She’s also open to meeting other pets and kids 14 and older. If you’re looking for a gentle, smart, loving girl and are willing to give her the time she needs to feel safe, Lola may be the dog for you!If you are interested in adopting, please visit Women`s Animal Center to fill out an application in person. We cannot accept any applications online or through email, and we cannot hold any specific animal for a potential adopter.You do not need an appointment to walk through our shelter, so please stop by any time during our adoption hours.You must follow the guidelines for our adoption process listed on our website (https://womensanimalcenter.org/our-animal-shelter/adoption-process-fees) to be able to meet and adopt one of our animals.If the animal you are interested in still has an active photo on our website, they are still at the shelter and available!PA Kennel License #1516
Photo of Kaiser Dowling

Kaiser Dowling

Mastiff

Male, 3 yrs 1 mo
Philadelphia, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
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Photo of Miss Meatball

Miss Meatball

Mastiff

Female, 2 yrs
Millville, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
Meet Miss Meatball! This beautiful brindle girl is Miss Meatball, a 2-year-old Mastiff mix who found herself at ARC after being picked up as a stray. Unfortunately, no one came forward to reclaim her, so now she’s ready to start the next chapter of her life with a family of her very own. Miss Meatball may have a big name and an even bigger head, but there’s a whole lot to love packed into this girl. She’s settling into shelter life while we continue learning more about her personality.When it comes to other dogs, Miss Meatball can be selective about her canine friends, so any potential doggy siblings would need to meet her here at the shelter to make sure everyone is comfortable and it’s a good match. One thing we know for sure? That face is pretty hard to resist. Her life before ARC may be a mystery, but we’re hoping her future includes a couch, plenty of love, and someone who thinks having a Meatball in the family sounds pretty perfect.
Photo of Ella (fka Bermuda)

Ella (fka Bermuda)

Mastiff

Female, 6 yrs 2 mos
Manchester, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Not good with cats, House-trained,
Story
Sweet. Kind, and gentle Ella is an 8-year-old brindle Mastiff. Her soulful eyes will stare you down and capture your heart at the same time. She is a loveable gentle giant ready for her forever family. Ella is super friendly and everyone she meets is her friend. With proper introduction, Ella has done well with both female and male dogs. Smaller dogs and cats are unknown. She’s quiet but still has a lot of life left in her and loves to play! She loves to fetch the ball and tug of war with her toys, going for walks. She especially loves car rides and is a great Co Pilot! Her favorite place is being snuggled and close to her people. She would probably do best in a home with older children because she may knock down the little kiddos because she thinks she’s a small dog. She is fine when left alone but of course cannot wait till her family comes home and will greet you with lots of love. She is house trained, up to date on vaccines, spayed, heartworm negative, and just an all-around healthy girl. Ella’s foster Mom cannot emphasize how great she is and knows that she will make someone the perfect soulmate!
Photo of Melvin

Melvin

Mastiff

Male, Young
McDonald, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Melvin is a young Boerboel mix, estimated to be about 1 year old, who came to us as a stray. We don't know much about his past, but we are excited to help him findthe bright future he deserves. Melvin is a big, goofy boy with an even bigger heart. He absolutely loves other dogs, especially dogs his own size, and nothing makes him happier than a good game of chase or some rough-and-tumble wrestling with a canine friend. Because he's still young, he's full of energy and doesn't always realize just how big he is. One of Melvin's sweetest qualities is how quickly he bonds with his people. He's a true shadow dog who wants to be wherever you are. Whether you're making dinner, watching TV, or working around the house, you will find a big slobbery face following right behind you. He loves being part of the family and is happiest when he's included. Melvin already has a great foundation for his new family. He's house-trained, crate-trained, and walks nicely on a leash, making the transition into his forever home that much easier. He still has plenty to learn, and needs someone who will teach him. He's been around children and has done well, though his size and enthusiastic play style mean he'll do best with a family that can help him continue learning good manners. Melvin is eager to please and will thrive with patient guidance, regular exercise, and lots of opportunities to play. Melvin should not be placed in a home with cats. He simply wants to play with them the same way he plays with big dogs, and because of his size and rough play style, it's just not safe for feline friends. If you're looking for a loyal companion who will stick by your side, make you laugh with his oversized puppy antics, and happily cover you in a little slobber along the way, Melvin may be the perfect fit. He didn't get to choose how his story started, but he's more than ready for a family to help write the rest of it. Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   August 17, 2026, 8:15 am
Photo of Melvin

Melvin

Mastiff

Male, Young
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Good with kids, Good with dogs, Not good with cats,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Melvin is a young Boerboel mix, estimated to be about 1 year old, who came to us as a stray. We don't know much about his past, but we are excited to help him findthe bright future he deserves. Melvin is a big, goofy boy with an even bigger heart. He absolutely loves other dogs, especially dogs his own size, and nothing makes him happier than a good game of chase or some rough-and-tumble wrestling with a canine friend. Because he's still young, he's full of energy and doesn't always realize just how big he is. One of Melvin's sweetest qualities is how quickly he bonds with his people. He's a true shadow dog who wants to be wherever you are. Whether you're making dinner, watching TV, or working around the house, you will find a big slobbery face following right behind you. He loves being part of the family and is happiest when he's included. Melvin already has a great foundation for his new family. He's house-trained, crate-trained, and walks nicely on a leash, making the transition into his forever home that much easier. He still has plenty to learn, and needs someone who will teach him. He's been around children and has done well, though his size and enthusiastic play style mean he'll do best with a family that can help him continue learning good manners. Melvin is eager to please and will thrive with patient guidance, regular exercise, and lots of opportunities to play. Melvin should not be placed in a home with cats. He simply wants to play with them the same way he plays with big dogs, and because of his size and rough play style, it's just not safe for feline friends. If you're looking for a loyal companion who will stick by your side, make you laugh with his oversized puppy antics, and happily cover you in a little slobber along the way, Melvin may be the perfect fit. He didn't get to choose how his story started, but he's more than ready for a family to help write the rest of it. Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   August 17, 2026, 8:15 am

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Use the search tool below to browse adoptable Mastiff puppies and adults Mastiff in Pennsylvania.

Mastiff puppies and dogs in Pennsylvania cities

Mastiff Puppies near me Mastiff in Aliquippa Mastiff in Allentown Mastiff in Altoona Mastiff in Ambler Mastiff in Ambridge Mastiff in Archbald Mastiff in Arnold Mastiff in Avalon Mastiff in Bangor Mastiff in Beaver Mastiff in Beaver Falls Mastiff in Bellefonte Mastiff in Bellevue Mastiff in Berwick Mastiff in Bethel Park Mastiff in Bethlehem Mastiff in Birdsboro Mastiff in Blakely Mastiff in Bloomsburg Mastiff in Braddock Mastiff in Bradford Mastiff in Brentwood Mastiff in Bridgeport Mastiff in Bridgeville Mastiff in Bristol Mastiff in Brookhaven Mastiff in Butler Mastiff in California Mastiff in Camp Hill Mastiff in Canonsburg Mastiff in Carbondale Mastiff in Carlisle Mastiff in Carnegie Mastiff in Castle Shannon Mastiff in Catasauqua Mastiff in Chambersburg Mastiff in Charleroi Mastiff in Chester Mastiff in Clairton Mastiff in Clarion Mastiff in Clarks Summit Mastiff in Clearfield Mastiff in Clifton Heights Mastiff in Coatesville Mastiff in Collegeville Mastiff in Collingdale Mastiff in Columbia Mastiff in Connellsville Mastiff in Conshohocken Mastiff in Coraopolis Mastiff in Corry Mastiff in Crafton Mastiff in Danville Mastiff in Darby Mastiff in Dickson City Mastiff in Donora Mastiff in Downingtown Mastiff in Doylestown Mastiff in Dubois Mastiff in Dunmore Mastiff in Duquesne Mastiff in Duryea Mastiff in Easton Mastiff in East Petersburg Mastiff in East Stroudsburg Mastiff in Edinboro Mastiff in Edwardsville Mastiff in Elizabethtown Mastiff in Ellwood City Mastiff in Emmaus Mastiff in Ephrata Mastiff in Erie Mastiff in Exeter Mastiff in Farrell Mastiff in Folcroft Mastiff in Fountain Hill Mastiff in Franklin Mastiff in Gettysburg Mastiff in Glassport Mastiff in Glenolden Mastiff in Greensburg Mastiff in Greenville Mastiff in Grove City Mastiff in Hanover Mastiff in Harrisburg Mastiff in Hatboro Mastiff in Hazleton Mastiff in Hellertown Mastiff in Hermitage Mastiff in Hollidaysburg Mastiff in Honesdale Mastiff in Hummelstown Mastiff in Huntingdon Mastiff in Indiana Mastiff in Jeannette Mastiff in Jefferson Hills Mastiff in Jenkintown Mastiff in Jersey Shore Mastiff in Jessup Mastiff in Jim Thorpe Mastiff in Johnstown Mastiff in Kennett Square Mastiff in Kingston Mastiff in Kittanning Mastiff in Kutztown Mastiff in Lancaster Mastiff in Lansdale Mastiff in Lansdowne Mastiff in Larksville Mastiff in Latrobe Mastiff in Lebanon Mastiff in Lehighton Mastiff in Lewisburg Mastiff in Lewistown Mastiff in Lititz Mastiff in Lock Haven Mastiff in Lower Burrell Mastiff in Mahanoy City Mastiff in Manheim Mastiff in McKeesport Mastiff in Mc Kees Rocks Mastiff in Meadville Mastiff in Mechanicsburg Mastiff in Media Mastiff in Middletown Mastiff in Millersville Mastiff in Milton Mastiff in Monaca Mastiff in Monessen Mastiff in Monongahela Mastiff in Monroeville Mastiff in Montoursville Mastiff in Moosic Mastiff in Morrisville Mastiff in Mount Carmel Mastiff in Mount Joy Mastiff in Mount Pleasant Mastiff in Munhall Mastiff in Murrysville Mastiff in Nanticoke Mastiff in Nazareth Mastiff in New Brighton Mastiff in New Castle Mastiff in New Cumberland Mastiff in New Holland Mastiff in New Kensington Mastiff in Norristown Mastiff in Northampton Mastiff in Norwood Mastiff in Oakmont Mastiff in Oil City Mastiff in Old Forge Mastiff in Olyphant Mastiff in Oxford Mastiff in Palmerton Mastiff in Palmyra Mastiff in Perkasie Mastiff in Philadelphia Mastiff in Phoenixville Mastiff in Pittsburgh Mastiff in Pittston Mastiff in Pleasant Hills Mastiff in Plum Mastiff in Plymouth Mastiff in Pottstown Mastiff in Pottsville Mastiff in Prospect Park Mastiff in Punxsutawney Mastiff in Quakertown Mastiff in Reading Mastiff in Red Lion Mastiff in Ridley Park Mastiff in Royersford Mastiff in Saint Marys Mastiff in Sayre Mastiff in Schuylkill Haven Mastiff in Scottdale Mastiff in Scranton Mastiff in Selinsgrove Mastiff in Sellersville Mastiff in Shamokin Mastiff in Sharon Mastiff in Sharon Hill Mastiff in Shenandoah Mastiff in Shillington Mastiff in Shippensburg Mastiff in Slatington Mastiff in Somerset Mastiff in Souderton Mastiff in South Williamsport Mastiff in State College Mastiff in Steelton Mastiff in Stroudsburg Mastiff in Sunbury Mastiff in Swarthmore Mastiff in Swissvale Mastiff in Swoyersville Mastiff in Tamaqua Mastiff in Tarentum Mastiff in Taylor Mastiff in Telford Mastiff in Titusville Mastiff in Turtle Creek Mastiff in Tyrone Mastiff in Uniontown Mastiff in Vandergrift Mastiff in Warren Mastiff in Washington Mastiff in Waynesboro Mastiff in West Chester Mastiff in West Mifflin Mastiff in West Pittston Mastiff in West View Mastiff in Whitehall Mastiff in White Oak Mastiff in Wilkes Barre Mastiff in Wilkinsburg Mastiff in Williamsport Mastiff in Wyomissing Mastiff in Yeadon Mastiff in York

Mastiff shelters & rescues in Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Pennsylvania. Browse these Mastiff rescues and shelters below.

Here are a few organizations

Rescue

Rescue Pets Serving Vets

4793 Red Rock Road, Benton , PA 17814

Pet Types: cats, dogs

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Shelter

Animal Resource Center

Millville , PA 17846

Pet Types: cats, dogs

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Shelter

Pike County Humane Society

189 Lee Road, Shohola , PA 18458

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Looking for a specific shelter or rescue?

If you're not seeing what you're looking for, try our shelter and rescue search. We have more than 17,000 organizations in our database with furry pals waiting for a new home!

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Want to learn more about adopting a Mastiff puppy or dog ?

We've got all the info you need on adopting and caring for a Mastiff puppy . Check out the links below for everything you ever wanted to know about Mastiff puppies and adults .

Mastiff information

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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