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Mastiff puppies and dogs in Ephrata, Pennsylvania

Looking for a Mastiff puppy or dog in Ephrata, Pennsylvania? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Ephrata, Pennsylvania

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Ephrata, Pennsylvania

These Mastiffs are available for adoption close to Ephrata, Pennsylvania.
Photo of Meatball

Meatball

Mastiff Mixed Breed (Large)

Male, 3 yrs 9 mos
York, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Not good with cats, Spayed or Neutered,
Story
Meatball is a sweet, goofy guy who's ready to find a family to call his own! He came to us as a stray, so we don't know much about his past, but we've loved getting to know him and watching his personality shine. When Meatball first arrived, he had a tail injury that required surgical repair, but he's healing well and showing more of his playful side every day. He may take a little time to warm up to new people, but once he decides you're a friend, you'll meet the total goofball hiding underneath that initial shyness. Meatball came in with another pup, so he may enjoy having a canine companion in his new home. As always, thoughtful management and proper introductions will be important to help set everyone up for success. No cats for him though! If you're looking for a fun-loving buddy who just needs a little patience and a chance to shine, Meatball is ready to meet you! 3159 Susquehanna Trail N York PA 17406 Kennel #3537
Photo of Professor Peepers

Professor Peepers

Mastiff American Pit Bull Terrier

Male, 3 yrs 9 mos
York, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
-
Story
I was found on Old York Rd, Fairview TWP
Photo of Athena *Courtesy Post*

Athena *Courtesy Post*

English Mastiff

Female, Adult
Exton, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with cats, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Meet Athena! Athena is a 4 year old gorgeous brindle mastiff. She is already spayed and has had gastropexy surgery done. Athena would benefit from training and would do best with someone who is strong enough for her as she is a leash puller. Athena is a big girl who needs assistance getting into vehicles. Athena needs a home with no cats, farm or small animals of any kind as she has a high prey drive.Click here to watch a video of Athena *Courtesy Post*.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   August 5, 2026, 3:05 pm
Photo of Jamaika

Jamaika

Mastiff

Female, 4 yrs 2 mos
Manchester, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
-
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Photo of Biggie

Biggie

Mastiff

Male, 1 mo
Manchester, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
-
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Photo of Smalls

Smalls

Mastiff

Male, 1 yr 1 mo
Manchester, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Spayed or Neutered,
Story
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Mastiff shelters & rescues in Ephrata, Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Ephrata, Pennsylvania. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Shelter

25.2 miles

York County SPCA

3159 Susquehanna Trail North, York, PA 17406

Pet Types: cats, birds, dogs, rabbits, reptiles, small animals

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Rescue

29.1 miles

Mastiffs to Mutts - Eastern PA

Exton, PA 19341

Pet Types: dogs

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Rescue

30.4 miles

Koch's Corsos & Rescues

Manchester, PA 17345

Pet Types: dogs

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Rescue

33.6 miles

Angel's Retreat

West Chester, PA 19382

Pet Types: dogs

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Rescue

34.1 miles

Adopt A Stray - PA transport

Harrisburg, PA 17105

Pet Types: dogs

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Rescue

34.2 miles

Mastiffs To Mutts - Central PA

Harrisburg, PA 17109

Pet Types: dogs

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Shelter

35.1 miles

Waiting Under the Willow Foundation - PA Transport

Harrisburg, PA 17112

Pet Types: dogs

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Shelter

35.3 miles

Hillside SPCA

51 SPCA Road, Pottsville, PA 17901

Pet Types: cats, dogs, rabbits, small animals

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Rescue

46.8 miles

Last Chance Ranch Animal Rescue

9 Beck Rd., Quakertown, PA 18951

Pet Types: cats, birds, dogs, farm animals, horses, rabbits, reptiles, small animals

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Shelter

49.4 miles

Peaceable Kingdom Shelter

1049 MacArthur Road, Whitehall, PA 18052

Pet Types: cats, dogs, rabbits, small animals

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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