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Mastiff puppies and dogs in Lancaster, Pennsylvania

Looking for a Mastiff puppy or dog in Lancaster, Pennsylvania? Adopt a Pet can help you find an adorable Mastiff near you.

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Adopt a Mastiff near you in Lancaster, Pennsylvania

We don't see any Mastiffs available for adoption right now, but new adoptable pets are added every day. Try a different search below!

Or, how about these Mastiffs in cities near Lancaster, Pennsylvania

These Mastiffs are available for adoption close to Lancaster, Pennsylvania.
Photo of Jamaika

Jamaika

Mastiff

Female, 4 yrs 3 mos
Manchester, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with kids, Good with dogs, Good with cats, Spayed or Neutered,
Story
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Photo of Biggie

Biggie

Mastiff

Male, 1 mo
Manchester, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Good with cats, Spayed or Neutered,
Story
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Photo of Smalls

Smalls

Mastiff

Male, 1 yr 1 mo
Manchester, PA
Size
(when grown) Large 61-100 lbs (28-45 kg)
Details
Good with dogs, Good with cats, Spayed or Neutered,
Story
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Photo of Picasso

Picasso

Mastiff

Male, 1 yr
Manchester, PA
Size
(when grown) -
Details
Good with dogs, House-trained,
Story
🎨 Meet Picasso — the happiest little work of art! 👅💙 Picasso is an energetic young boy with a heart of gold and a tongue that has a personality all its own! He came to us with a jaw deformity, which is why his tongue is always sticking out—and honestly, it just makes his adorable face that much more fun. 😍 This sweet boy has a wonderful, kind demeanor and is always ready to enjoy life. He’s still learning all the rules of being a good boy, but he’s eager to learn and doing a great job! 🐾 Picasso is already working on: • Walking nicely on leash • Sit • Come • Down • Learning “okay” as his release word for food • Crate trained Picasso is a mid-to-high-energy boy, so he’d love a family ready to keep him busy, give him plenty of playtime and continue helping him learn. In return, you’ll get a happy, affectionate, goofy boy who is sure to bring plenty of smiles into your life. His tongue may stick out, but so does his personality! 😜 🎨 Picasso is ready to create a masterpiece of a life with his forever family.
Photo of Thalia

Thalia

Mastiff

Female, 2 yrs 4 mos
Manchester, PA
Size
(when grown) -
Details
Spayed or Neutered,
Story
Meet Thalia! Thalia is a sweet, happy girl who always seems to have a wagging tail and is ready to soak up all the attention you have to give. Since settling into her foster home, she has begun to decompress and show more of her personality, gaining confidence and starting to explore the world around her. Thalia does well with calm dogs and prefers to walk in the back of the pack, taking everything in at her own pace. On walks, she has shown very little prey drive. She has encountered squirrels and even a fox without much interest beyond mild curiosity—after all, they seem like pretty strange-looking dogs to her! While Thalia has not yet been cat tested, her calm and curious reactions to wildlife suggest she may do well with cats. As with any new introduction, we would recommend a slow and proper transition. We're still getting to know this lovely girl and will share more about her personality as she continues to settle in and blossom. For now, we can tell you that Thalia is a joyful, affectionate companion who is ready to find a family of her own.
Photo of Athena *Courtesy Post*

Athena *Courtesy Post*

English Mastiff

Female, Adult
Harrisburg, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
Not good with cats, Spayed or Neutered,
Story
You can fill out an adoption application online on our official website. Fill out an Adoption Application Meet Athena! Athena is a 4 year old gorgeous brindle mastiff. She is already spayed and has had gastropexy surgery done. Athena would benefit from training and would do best with someone who is strong enough for her as she is a leash puller. Athena is a big girl who needs assistance getting into vehicles. Athena needs a home with no cats, farm or small animals of any kind as she has a high prey drive.Click here to watch a video of Athena *Courtesy Post*.Visit this organization's web site to see any additional information available about this pet. Application Fees, Adoption Donations and Rescue Policy: Please know that 100% of our fees and donations pay for the costs of rescuing dogs. These include but are not limited to pull fees from shelters, veterinary examinations, vaccinations, medications and care, microchips, neuter/spay surgeries, heartworm treatments, behavior evaluations, and foster care, as needed. Important notes before applying. Approved adopters must have their primary residence in one of the following states: Delaware, Maryland, Michigan, New Jersey, Ohio, Pennsylvania, West Virginia, Virginia, and parts of North Carolina and Kentucky. You must be at least 21 years of age to apply and legally sign our contract for adoption. Applications must be completed by the homeowner.  We do not adopt giant breed dogs to renters. If you are renting, and you are applying to adopt a dog that is not a giant breed, permission to adopt an animal must be obtained from the landlord or property owner. We do not adopt giant breed dogs to homes with children under 6 years of age. Homes with children should have a fenced yard. Applications will be denied if anyone residing in the household has a record indicating drug/alcohol abuse, theft, or violence. Pets currently in the applicant's home must have a history of appropriate veterinary care. Homes with intact dogs will not be approved for adoption.  Proof of any of the following exceptions is required: The intact dog is a working member of a law enforcement, or search and rescue/recovery team. The intact dog is registered under the auspices of the American Kennel Club and is actively being shown. A veterinarian has determined the sterilization procedure would harm the intact dog.  We believe in Force Free Training Methods and do not approve of methods or devices using pain or force to control the dog, or to deter undesirable behavior.  Homes with highly varnished steps must have carpeting, securely fixed stair treads, or a non-skid surface. **We encourage you to remediate potential safety issues while your application is under review, prior to the home visit. ​Any inside steps to which the dog(s) have access, must have carpeting, securely fixed stair treads, or a non-skid surface. Homes with highly varnished floors must have non-slip area rugs or mats wherever your animal walks or rests frequently.  **Puppy Adoption Policy** To ensure proper house training and socialization, puppies will only be adopted to homes where an adult will not be away more than an hour per day, per month of age of the puppy, up to 6 months. Certain large-breed dogs should not be sterilized prior to 12 - 18 months of age.  If you adopt an intact puppy, you will sign an adoption contract agreeing to have the dog sterilized at your expense at the time your veterinarian recommends. Proof of sterilization must be provided to Mastiffs To Mutts Rescue as soon as the procedure is completed.  If the puppy is not sterilized as required, Mastiffs To Mutts Rescue reserves the right to claim legal ownership of the dog.  For additional information please review our FAQs or contact mastiffstomutts@gmail.com **Mastiffs To Mutts Rescue reserves the right to approve or deny any adoption that occurs through this organization without disclosure.  We reserve the right to make exceptions for special circumstances. **PA Kennel License: 05845   August 16, 2026, 9:07 pm

These pups are in Lancaster, Pennsylvania too!

Below are our newest added Mastiffs available for adoption in Lancaster, Pennsylvania. To see more adoptable Mastiffs in Lancaster, Pennsylvania, use the search tool below to enter specific criteria!
Photo of Winston

Winston

St. Bernard

Male, 5 yrs
Lancaster, PA
Size
(when grown) X-Large 101 lbs (46 kg) or more
Details
-
Story
Wowzers, it`s Winston! This big, beautiful St. Bernard was sadly found in an area where dogs are often dumped. He hasn`t let that get him down and is a cheery pup who absolutely loves being around people. He would likely do well living with children of all ages since he is a gentle giant. He is open to possibly living with other animals as well with proper introductions. Winston is a pretty well-mannered dog and just wants companionship and a family of his own. ---If you are interested in adopting, please come prepared --bring a photo ID, proof of address, and everyone in the home including resident dogs with vaccination history. We are open daily 12-6pm.---The Pennsylvania SPCA - Lancaster Center848 S. Prince St. Lancaster PA 17603Kennel #16516717-917-6979lancaster@pspca.org

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Mastiff puppies and dogs in nearby cities

Related breeds in Lancaster, Pennsylvania

Mastiff shelters & rescues in Lancaster, Pennsylvania

There are animal shelters and rescues that focus specifically on finding great homes for Mastiff puppies in Lancaster, Pennsylvania. Browse these Mastiff rescues and shelters below.

Here are a few organizations closest to you:

Rescue

21.4 miles

Koch's Corsos & Rescues

Manchester, PA 17345

Pet Types: dogs

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Rescue

29.8 miles

Mastiffs To Mutts - Central PA

Harrisburg, PA 17109

Pet Types: dogs

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Shelter

31.5 miles

Waiting Under the Willow Foundation - PA Transport

Harrisburg, PA 17112

Pet Types: dogs

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Rescue

35.9 miles

Mastiffs to Mutts - Eastern PA

Exton, PA 19341

Pet Types: dogs

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Want to learn more about adopting a Mastiff puppy or dog?

We've got all the info you need on adopting and caring for a Mastiff puppy. Check out the links below for everything you ever wanted to know about Mastiff puppies and adults.

Mastiff basics

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Where do Mastiffs come from? How many types of Mastiffs are there? From the history of the breed to question about average height, weight and size, brush up on these basic facts about the Mastiff.

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